DSpace Repository

Browsing INEU by Author "Surace, Ezequiel Ignacio"

Browsing INEU by Author "Surace, Ezequiel Ignacio"

Sort by: Order: Results:

  • A neurodegenerative disease landscape of rare mutations in Colombia due to founder effects 
    Acosta Uribe, Juliana; Aguillón, David; Cochran, J. Nicholas; Giraldo, Margarita; Madrigal, Lucía; Killingsworth, Bradley W.; Singhal, Rijul; Labib, Sarah; Alzate, Diana; Velilla, Lina M.; Moreno, Sonia; García, Gloria P.; Saldarriaga, Amanda; Piedrahita, Francisco; Hincapié, Liliana; López, Hugo E.; Perumal, Nithesh; Surace, Ezequiel Ignacio; Itzcovich, Tatiana; Allegri, Ricardo Francisco (BioMed Central, 2022-03-08)
    Background: The Colombian population, as well as those in other Latin American regions, arose from a recent tri-continental admixture among Native Americans, Spanish invaders, and enslaved Africans, all of whom passed ...
  • Advancing biobanking in Latin America: success stories and challenges ahead 
    Sevlever, Gustavo Emilio; Crivelli, Lucía; Kimie Suemoto, Claudia; Surace, Ezequiel Ignacio; Taratuto, Ana Lía (Elsevier, 2025-03-03)
    Resumen no disponible
  • Alzheimer's polygenic risk scores are associated with cognitive phenotypes in Down syndrome 
    Gorijala, Priyanka; Aslam, M. Muaaz; Dang, Lam-Ha T.; Xicota, L.; Fernández, María V.; Sung, Yun Ju; Fan, Kang-Hsien; Feingold, Eleanor; Surace, Ezequiel Ignacio; Chhatwal, Jasmeer P.; Hom, Christy L.; Dominantly Inherited Alzheimer Network; NIA-LOAD family study, for the Alzheimer's Biomarkers Consortium-Down Syndrome (ABC-DS) Investigators; Hartley, Sigan L.; Hassenstab, Jason; Perrin, Richard J.; Mapstone, Mark; Zaman, Shahid H.; Ances, Beau M.; Kamboh, M. Ilyas; Lee, Joseph H.; Cruchaga, Carlos (John Wiley & Sons, 2023-10-19)
    Introduction: This study aimed to investigate the influence of the overall Alzheimer's disease (AD) genetic architecture on Down syndrome (DS) status, cognitive measures, and cerebrospinal fluid (CSF) biomarkers. Methods: ...
  • Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer's disease 
    Johnson, Erik C. B.; Bian, Shijia; Haque, Rafi U.; Carter, E. Kathleen; Watson, Caroline M.; Gordon, Brian A.; Ping, Lingyan; Duong, Duc M.; Epstein, Michael P.; McDade, Eric; Barthélemy, Nicolas R.; Karch, Celeste M.; Xiong, Chengjie; Cruchaga, Carlos; Perrin, Richard J.; Wingo, Aliza P.; Dominantly Inherited Alzheimer Network (Nature Publishing Company, 2023-08-07)
    Alzheimer's disease (AD) pathology develops many years before the onset of cognitive symptoms. Two pathological processes-aggregation of the amyloid-β (Aβ) peptide into plaques and the microtubule protein tau into ...
  • CSF proteomics identifies early changes in autosomal dominant Alzheimer's disease 
    Shen, Yuanyuan; Timsina, Jigyasha; Heo, Gyujin; Beric, Aleksandra; Ali, Muhammad; Wang, Ciyang; Yang, Chengran; Wang, Yueyao; Western, Daniel; Liu, Menghan; Gorijala, Priyanka; Budde, John P.; Do, Anh; Liu, Haiyan; Gordon, Brian A.; Llibre Guerra, Jorge J.; Surace, Ezequiel Ignacio; Allegri, Ricardo Francisco; Dominantly Inherited Alzheimer Network (Cell Press, 2024-09-26)
    In this high-throughput proteomic study of autosomal dominant Alzheimer's disease (ADAD), we sought to identify early biomarkers in cerebrospinal fluid (CSF) for disease monitoring and treatment strategies. We examined CSF ...
  • Dominantly inherited Alzheimer's disease in Latin America: Genetic heterogeneity and clinical phenotypes 
    Llibre Guerra, Jorge J.; Li, Yan; Allegri, Ricardo Francisco; Chrem Méndez, Patricio Alexis; Surace, Ezequiel Ignacio; Llibre Rodríguez, Juan J.; Sosa, Ana Luisa; Aláez-Verson, Carmen; Longoria, Erika-Mariana; Tellez, Alberto; Carrillo Sánchez, Karol; Flores Lagunes, Luis Leonardo; Sánchez, Victor; Tadao Takada, Leonel; Nitrini, Ricardo; Ferreira Frota, Norberto Anizio; Benevides Lima, Joyce; Lopera, Francisco; Ramírez, Laura; Jiménez Velázquez, Ivonne (John Wiley & Sons, 2021-04)
    Introduction: A growing number of dominantly inherited Alzheimer's disease (DIAD) cases have become known in Latin American (LatAm) in recent years. However, questions regarding mutation distribution and frequency by country ...
  • Generation of a human induced pluripotent stem cell line (INEUi001-A) from an amyotrophic lateral sclerosis/frontotemporal dementia patient with a C9ORF72 G4C2 genotype of <2 (GGGGCCG) and 10 repeats 
    Nievas, Micaela; Romorini, Leonardo; Isaja, Luciana; Clas, Giulia Solange; Rodríguez Varela, María Soledad; Mucci, Sofía; Itzcovich, Tatiana; de Ambrosi, Bruno; Scassa, María Élida; Sevlever, Gustavo Emilio; Surace, Ezequiel Ignacio; Marazita, Mariela Claudia (Elsevier, 2023-03-22)
    Human induced pluripotent stem cell (hiPSC) line INEUi001-A was reprogrammed from peripheral blood mononuclear cells (PBMC) using the lentiviral-hSTEMCCA-loxP vector. PBMCs were obtained from a 75- year-old female ALS/FTD ...
  • Generation of a human induced pluripotent stem cell line from a familial Alzheimer's disease PSEN1 T119I patient 
    Isaja, Luciana; Rodríguez Varela, María Soledad; Marazita, Mariela Claudia; Mucci, Sofía; Itzcovich, Tatiana; Chrem Méndez, Patricio Alexis; Niikado, Matías; Ferriol Laffouillere, Sofía Luján; Allegri, Ricardo Francisco; Martinetto, Horacio; Sevlever, Gustavo Emilio; Scassa, María Élida; Surace, Ezequiel Ignacio; Romorini, Leonardo (Elsevier, 2021-04-05)
    Human induced pluripotent stem cells (hiPSC) line FLENIi001-A was reprogrammed from dermal fibroblasts using the lentiviral-hSTEMCCA-loxP vector. Fibroblasts were obtained from a skin biopsy of a 72-year-old Caucasian male ...
  • Generation of human induced pluripotent stem cell lines from two down syndrome patients, including a down syndrome/Alzheimer's disease case (FLENIi002-A) and a beta-amyloid-resistant case (FLENIi003-A) 
    Clas, Giulia Solange; Marazita, Mariela Claudia; Pertierra, Lucía; Vázquez, Silvia; Isaja, Luciana; Rodríguez Varela, María Soledad; Mucci, Sofía; Helou, María Belén; Tapajóz Pereira de Sampaio, Fernanda; Magrath Guimet, Nahuel; Bérgamo, Yanina; Allegri, Ricardo Francisco; Sevlever, Gustavo Emilio; Scassa, María Élida; Surace, Ezequiel Ignacio; Romorini, Leonardo (Elsevier, 2025-05-01)
    Two human induced pluripotent stem cell (hiPSC) lines, FLENIi002-A and FLENIi003-A, were generated from peripheral blood mononuclear cells (PBMCs) using the lentiviral-hSTEMCCA-loxP vector. FLENIi002-A was derived from a ...
  • Latin American Initiative for Lifestyle Intervention to Prevent Cognitive Decline (LatAm-FINGERS): Study design and harmonization 
    Crivelli, Lucía; Calandri, Ismael Luis; Kimie Suemoto, Claudia; Salinas Contreras, Rosa María; Velilla, Lina M.; Sanches Yassuda, Mónica; Caramelli, Paulo; Lopera, Francisco; Nitrini, Ricardo; Sevlever, Gustavo Emilio; Sosa, Ana Luisa; Acosta, Daisy; Bérgamo, Yanina; Clarens, María Florencia; Demey, Ignacio; Helou, María Belén; Martin, María Eugenia; Querzé, Diego; Surace, Ezequiel Ignacio; Allegri, Ricardo Francisco (Wiley, 2023-05-19)
    Introduction: Latin American Initiative for Lifestyle Intervention to Prevent Cognitive Decline (LatAm-FINGERS) is the first non-pharmacological multicenter randomized clinical trial (RCT) to prevent cognitive impairment ...
  • Longitudinal clinical, cognitive and biomarker profiles in dominantly inherited versus sporadic early-onset Alzheimer's disease 
    Llibre Guerra, Jorge J.; Iaccarino, Leonardo; Coble, Dean; Edwards, Lauren; Li, Yan; McDade, Eric; Strom, Amelia; Gordon, Brian A.; Mundada, Nidhi; Schindler, Suzanne E.; Tsoy, Elena; Ma, Yinjiao; Lu, Ruijin; Fagan, Anne M.; Benzinger, Tammie L.S.; Soleimani Meigooni, David; Aschenbrenner, Andrew J.; Allegri, Ricardo Francisco; Patricio Alexis, Chrem Méndez; Surace, Ezequiel Ignacio (Oxford University Press, 2023-10-18)
    Approximately 5% of Alzheimer's disease cases have an early age at onset (<65 years), with 5-10% of these cases attributed to dominantly inherited mutations and the remainder considered as sporadic. The extent to which ...
  • Neuropsychological profile of Alzheimer’s disease based on amyloid biomarker findings results from a South American cohort. Appl Neuropsychol Adult 1–6. 
    Clarens, María Florencia; Crivelli, Lucía; Calandri, Ismael Luis; Chrem Méndez, Patricio Alexis; Martín, María Eugenia; Russo, María Julieta; Campos, Jorge; Surace, Ezequiel Ignacio; Vázquez, Silvia; Sevlever, Gustavo Emilio; Allegri, Ricardo Francisco (Taylor & Francis Group, 2020-04-30)
    Objective: Increased life expectancy and exponential growth of adults suffering from Alzheimer's disease (AD) worldwide, has led to biomarkers incorporation for diagnosis in early stages. Use of neuropsychological testing ...
  • A novel mutation in PSEN1 (p.T119I) in an Argentine family with early- and late-onset Alzheimer's disease 
    Itzcovich, Tatiana; Chrem Méndez, Patricio Alexis; Vázquez, Silvia; Barbieri-Kennedy, Micaela; Niikado, Matías; Martinetto, Horacio; Allegri, Ricardo Francisco; Sevlever, Gustavo Emilio; Surace, Ezequiel Ignacio (Elsevier, 2020-01)
    Mutations inPSEN1are the most common cause of early-onset Alzheimer’s disease (AD). In this article,we present an Argentine family with autosomal dominant early- and late-onset AD. The proband and 6family members were ...
  • Prognostic value of ATN Alzheimer biomarkers: 60-month follow-up results from the Argentine Alzheimer’s Disease Neuroimaging Initiative. 
    Allegri, Ricardo Francisco; Chrem Méndez, Patricio Alexis; Calandri, Ismael Luis; Cohen, Gabriela; Martín, María Eugenia; Russo, María Julieta; Crivelli, Lucía; Pertierra, Lucía; Tapajóz Pereira de Sampaio, Fernanda; Clarens, María Florencia; Campos, Jorge; Nahas, Federico Ezequiel; Vázquez, Silvia; Surace, Ezequiel Ignacio; Sevlever, Gustavo Emilio (Elsevier, 2020)
    Purpose: To describe results of the Amyloid, Tau, Neurodegeneration (ATN) research framework classification in the Argentine-Alzheimer’s Disease Neuroimaging Initiative (arg-ADNI) cohort. Methods: Twenty-three patients ...

Search DSpace


Browse

My Account