Browsing INEU by Subject "Glioma"

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Evaluation of Baculoviruses as Gene Therapy Vectors for Brain Cancer

Garcia Fallit, Matías; Pidre, Matías L.; Asad, Antonela S.; Peña Agudelo, Jorge A.; Vera, Mariana Belén; Nicola Candia, Alejandro J.; Sagripanti, Sofia B.; Pérez Kuper, Melanie; Amorós Morales, Leslie C.; Marchesini, Abril; Gonzalez, Nazareno; Caruso, Carla M.; Romanowski, Víctor; Seilicovich, Adriana; Videla Richardson, Guillermo Agustín; Zanetti, Flavia A.; Candolfi, Marianela (MDPI, 2023-02-22)

We aimed to assess the potential of baculoviral vectors (BV) for brain cancer gene therapy. We compared them with adenoviral vectors (AdV), which are used in neuro-oncology, but for which there is pre-existing immunity. ...
Noxa and Mcl-1 expression influence the sensitivity to BH3-mimetics that target Bcl-xL in patient-derived glioma stem cells

Vera, Mariana Belén; Morris-Hanon, Olivia; Nogueiras, Germán Ignacio; Ripari, Luisina Belén; Esquivel, Myrian Inés; Perez-Castro, Carolina; Romorini, Leonardo; Sevlever, Gustavo Emilio; Scassa, María Élida; Videla Richardson, Guillermo Agustín (Nature Publishing Group, 2022-10-22)

The recurrence of Glioblastoma is partly attributed to the highly resistant subpopulation of glioma stem cells. A novel therapeutic approach focuses on restoring apoptotic programs in these cancer stem cells, as they are ...

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