INEU: Recent submissions

  • Neural and subjective effects of inhaled N,N-dimethyltryptamine in natural settings 
    Pallavicini, Carla; Cavanna, Federico; Zamberlan, Federico; de la Fuente, Laura A.; Ilksoy, Yayla; Perl, Yonatan Sanz; Arias, Mauricio; Romero, Celeste; Carhart-Harris, Robin; Timmermann, Christopher; Tagliazucchi, Enzo (Sage, 2021-02-10)
    Background: N,N-dimethyltryptamine is a short-acting psychedelic tryptamine found naturally in many plants and animals. Few studies to date have addressed the neural and psychological effects of N,N-dimethyltryptamine ...
  • Structural brain abnormalities in schizophrenia in adverse environments: examining the effect of poverty and violence in six Latin American cities 
    Crossley, Nicolas; Zugman, Andre; Reyes-Madrigal, Francisco; Czepielewski, Leticia; Castro, Mariana Nair; Diaz-Zuluaga, Ana María; Pineda-Zapata, Julián; Reckziegel, Ramiro; Gadelha, Ary; Jackowski, Andrea; Noto, Cristiano; Alliende Serra, Luz Maria; Iruretagoyena, Bárbara; Ossandon, Tomas; Ramirez-Mahaluf, Juan Pablo; Castañeda, Carmen Paz; Gonzalez-Valderrama, Alfonso; Nachar, Rubén; Guinjoan, Salvador Martín; ANDES Network (Cambridge University Press, 2020-08-18)
    Background Social and environmental factors such as poverty or violence modulate the risk and course of schizophrenia. However, how they affect the brain in patients with psychosis remains unclear. Aims We studied how ...
  • Automatic and unbiased segmentation and quantification of myofibers in skeletal muscle 
    Waisman, Ariel; Norris, Alessandra; Costa, Martín Elías; Kopinke, Daniel (Nature Publishing Group, 2021-01-22)
    Skeletal muscle has the remarkable ability to regenerate. However, with age and disease muscle strength and function decline. Myofiber size, which is affected by injury and disease, is a critical measurement to assess ...
  • HLA-G gene editing: a novel therapeutic alternative in cancer immunotherapy 
    Palma, María Belén; Tronik-Le Roux, Diana; Amín, Guadalupe; Castañeda, Sheila; Möbbs, Alan Miqueas; Scarafía, María Agustina; La Greca, Alejandro; Daouya, Marina; Poras, Isabelle; Inda, Ana María; Moro, Lucía Natalia; Carosella, Edgardo D.; García, Marcela N.; Miriuka, Santiago Gabriel (bioRxiv, 2021-01-22)
    Cancer immunotherapies based mainly on the blockade of immune-checkpoint (IC) molecules by anti-IC antibodies offer new alternatives for treatment in oncological diseases. However, a considerable proportion of patients ...
  • miR-302 family, miR-145 and miR-296 temporal expression profile along the cell cycle of human pluripotent stem cells 
    Rodríguez Varela, María Soledad; Mucci, Sofía; Videla Richardson, Guillermo Agustín; Isaja, Luciana; Sevlever, Gustavo Emilio; Scassa, María Élida; Romorini, Leonardo (Elsevier, 2021-01-21)
    Human pluripotent stem cells (hPSCs), like embryonic (hESCs) and induced pluripotent stem cells (hiPSCs), exhibit an unusual cell cycle structure characterized by a short G1 phase and cells being most of time in S phase. ...
  • Downregulation of E-cadherin in pluripotent stem cells triggers partial EMT 
    Aban, Cyntia; Lombardi, Antonella; Neiman, Gabriel; Biani, María Celeste; La Greca, Alejandro; Waisman, Ariel; Moro, Lucía Natalia; Sevlever, Gustavo Emilio; Miriuka, Santiago Gabriel; Luzzani, Carlos Daniel (Nature Publishing Group, 2021-01-21)
    Epithelial to mesenchymal transition (EMT) is a critical cellular process that has been well characterized during embryonic development and cancer metastasis and it also is implicated in several physiological and pathological ...
  • Myostatin gene editing by CRISPR/Cas9 technology of Brangus fetal fibroblasts to produce edited embryos by cloning 
    Bastón, Juan Ignacio; Viale, Diego Luis; Olguín, Martín; Wiedenmann, Elisabet; Arnold, Victoria; Suva, Mariana; Luzzani, Carlos Daniel; Miriuka, Santiago Gabriel; Moro, Lucía Natalia; Vichera, Gabriel (Csiro Publishing, 2021-01-08)
    Some European cattle breeds, such as Charolais and Maine Anjou, have natural mutations in the myostatin gene (MSTN) that inhibit its expression and result in an increase in muscle mass and protein content. An innovative ...
  • White matter fiber density abnormalities in cognitively normal adults at risk for late-onset Alzheimer's disease 
    Sánchez, Stella Maris; Duarte-Abritta, Bárbara; Abulafia, Carolina; De Pino, Gabriela; Bocaccio, Hernán; Castro, Mariana Nair; Sevlever, Gustavo Emilio; Fonzo, Greg A.; Nemeroff, Charles B.; Gustafson, Deborah R.; Guinjoan, Salvador Martín; Villarreal, Mirta Fabiana (Elsevier, 2020-02)
    Tau accumulation affecting white matter tracts is an early neuropathological feature of late-onset Alzheimer's disease (LOAD). There is a need to ascertain methods for the detection of early LOAD features to help with ...
  • Meditation Increases the Entropy of Brain Oscillatory Activity 
    Martínez Vivot, Rocío; Pallavicini, Carla; Zamberlan, Federico; Vigo, Daniel Eduardo; Tagliazucchi, Enzo (Elsevier, 2020-04-01)
    We address the hypothesis that the entropy of neural dynamics indexes the intensity and quality of conscious content. Previous work established that serotonergic psychedelics can have a dysregulating effect on brain activity, ...
  • PIWI-interacting RNAs are differentially expressed during cardiac differentiation of human pluripotent stem cells 
    La Greca, Alejandro; Scarafía, María Agustina; Hernández Cañás, María Clara; Pérez, Nelba; Castañeda, Sheila; Colli, Carolina; Miqueas Möbbs, Alan; Santín Velazque, Natalia Lucía; Neiman, Gabriel; Garate, Ximena; Aban, Cyntia; Waisman, Ariel; Moro, Lucía Natalia; Sevlever, Gustavo Emilio; Luzzani, Carlos Daniel; Miriuka, Santiago Gabriel (Public Library of Science, 2020-05-05)
    PIWI-interacting RNAs (piRNAs) are a class of non-coding RNAs initially thought to be restricted exclusively to germline cells. In recent years, accumulating evidence has demonstrated that piRNAs are actually expressed in ...
  • Comment on: The Geographic Diversity of Spinocerebellar Ataxias (SCAs) in the Americas 
    Guarnaschelli, Marlen; Rossi, Malco Damián; Zajd, Ana; Igarreta, Pilar (Wiley, 2020-01-25)
    Resumen no disponible
  • A novel mutation in PSEN1 (p.Arg41Ser) in an Argentinian woman with early onset Parkinsonism 
    Gatto, Emilia M.; Rojas, Galeno J.; Nemirovsky, Sergio I.; Da Prat, Gustavo; Persi, Gabriel; Cesarini, Martin; Etcheverry, Jose L.; Gonzalez Rojas, Natalia; Parisi, Virginia; Cordoba, Marta; Sevlever, Gustavo Emilio; Allegri, Ricardo Francisco; Turjanski, Adrian G. (Elsevier, 2020-08)
    Introduction: Mutations in presenilin-1 (PSEN1) account for the majority of cases of familial autosomal dominant early-onset Alzheimer's disease (AD) as well as in sporadic forms. Atypical presentations are reported including ...
  • Disrupted functional connectivity of the locus coeruleus in healthy adults with parental history of Alzheimer's disease 
    Del Cerro, Inés; Villarreal, Mirta Fabiana; Abulafia, Carolina; Duarte-Abritta, Bárbara; Sánchez, Stella Maris; Castro, Mariana Nair; Bocaccio, Hernán; Ferrer, Isidre; Menchón, José Manuel; Sevlever, Gustavo Emilio; Nemeroff, Charles B.; Soriano-Mas, Carles; Guinjoan, Salvador Martín (Pergamon Press, 2020-04)
    Prevention and early treatment strategies for Alzheimer's disease (AD) are hampered by the lack of research biomarkers. Neuropathological changes in the Locus Coeruleus (LC) are detected early in AD, and noradrenaline plays ...
  • Structural brain abnormalities in schizophrenia in adverse environments: examining the effect of poverty and violence in six latin american cities 
    Crossley, Nicolas; Zugman, Andre; Reyes-Madrigal, Francisco; Czepielewski, Leticia; Castro, Mariana Nair; Diaz-Zuluaga, Ana María; Pineda-Zapata, Julián; Reckziegel, Ramiro; Gadelha, Ary; Jackowski, Andrea; Noto, Cristiano; Alliende Serra, Luz Maria; Iruretagoyena, Bárbara; Ossandon, Tomas; Ramirez-Mahaluf, Juan Pablo; Castañeda, Carmen Paz; Gonzalez-Valderrama, Alfonso; Nachar, Rubén; León-Ortiz, Pablo; Undurraga, Juan; Lopez-Jaramillo, Carlos; Guinjoan, Salvador Martín; Gama, Clarissa; De la Fuente-Sandoval, Camilo; Bressan, Rodrigo (Oxford University Press, 2020-04)
    Background Social and environmental factors such as poverty or violence, modulate the risk and course of schizophrenia, but how they affect the brain in patients with psychosis remains unclear. We here studied how they ...
  • Neuropsychological profile of Alzheimer’s disease based on amyloid biomarker findings results from a South American cohort. Appl Neuropsychol Adult 1–6. 
    Clarens, María Florencia; Crivelli, Lucía; Calandri, Ismael Luis; Chrem Méndez, Patricio Alexis; Martín, María Eugenia; Russo, María Julieta; Campos, Jorge; Surace, Ezequiel Ignacio; Vázquez, Silvia; Sevlever, Gustavo Emilio; Allegri, Ricardo Francisco (Taylor & Francis Group, 2020-04-30)
    Objective: Increased life expectancy and exponential growth of adults suffering from Alzheimer's disease (AD) worldwide, has led to biomarkers incorporation for diagnosis in early stages. Use of neuropsychological testing ...
  • Prognostic value of ATN Alzheimer biomarkers: 60-month follow-up results from the Argentine Alzheimer’s Disease Neuroimaging Initiative. 
    Allegri, Ricardo Francisco; Chrem Méndez, Patricio Alexis; Calandri, Ismael Luis; Cohen, Gabriela; Martín, María Eugenia; Russo, María Julieta; Crivelli, Lucía; Pertierra, Lucía; Tapajóz Pereira de Sampaio, Fernanda; Clarens, María Florencia; Campos, Jorge; Nahas, Federico Ezequiel; Vázquez, Silvia; Surace, Ezequiel Ignacio; Sevlever, Gustavo Emilio (Elsevier, 2020)
    Purpose: To describe results of the Amyloid, Tau, Neurodegeneration (ATN) research framework classification in the Argentine-Alzheimer’s Disease Neuroimaging Initiative (arg-ADNI) cohort. Methods: Twenty-three patients ...
  • Acute amnestic syndromes 
    Alessandro, Lucas; Ricciardi, Mario Emiliano; Chaves, Hernán; Allegri, Ricardo Francisco (Elsevier, 2020-03-18)
    Acute amnestic syndromes are usually rare clinical events occurring in emergency situations. Etiological diagnosis can be challenging and underlying causes diverse. They can be transient and totally reversible, or accompanied ...
  • Disease activity impacts disability progression in primary progressive multiple sclerosis 
    Marrodán, Mariano; Bensi, Catalina; Pappolla, Agustín; Rojas, Juan Ignacio; Gaitán, María Inés; Ysrraelit, María Célica; Negrotto, Laura; Fiol, Marcela Paula; Patrucco, Liliana; Cristiano, Edgardo; Farez, Mauricio Franco; Correale, Jorge (Elsevier, 2019-12-14)
    Background Although solid information on the natural history of primary progressive multiple sclerosis (PPMS) is available, evidence regarding impact of disease activity on PPMS progression remains controversial. Objective To ...
  • A novel mutation in PSEN1 (p.T119I) in an Argentine family with early- and late-onset Alzheimer's disease 
    Itzcovich, Tatiana; Chrem Méndez, Patricio Alexis; Vázquez, Silvia; Barbieri-Kennedy, Micaela; Niikado, Matías; Martinetto, Horacio; Allegri, Ricardo Francisco; Sevlever, Gustavo Emilio; Surace, Ezequiel Ignacio (Elsevier, 2020-01)
    Mutations inPSEN1are the most common cause of early-onset Alzheimer’s disease (AD). In this article,we present an Argentine family with autosomal dominant early- and late-onset AD. The proband and 6family members were ...
  • Nosology and Phenomenology of Psychosis in Movement Disorders 
    Rossi, Malco Damián; Farcy, Nicole; Starkstein, Sergio E.; Merello, Marcelo (Wiley, 2020-01-07)
    Background Psychotic symptoms such as delusions and hallucinations are part of the clinical picture of several conditions presenting movement disorders. Phenomenology and epidemiology of psychosis in Parkinson's disease ...

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