INEU: Recent submissions

  • Change in Cerebrospinal Fluid Tau Microtubule Binding Region Detects Symptom Onset, Cognitive Decline, Tangles, and Atrophy in Dominantly Inherited Alzheimer's Disease 
    Horie, Kanta; Li, Yan; Barthélemy, Nicolas R.; Gordon, Brian A.; Hassenstab, Jason; Benzinger, Tammie L.S.; Fagan, Anne M.; Morris, John C.; Karch, Celeste M.; Xiong, Chengjie; Allegri, Ricardo Francisco; Chrem Méndez, Patricio Alexis; Ikeuchi, Takeshi; Kasuga, Kensaku; Noble, James M.; Farlow, Martin R.; Chhatwal, Jasmeer P.; Day, Gregory S.; Schofield, Peter R.; Dominantly Inherited Alzheimer Network (Wiley, 2023-03-16)
    Objective: Identifying cerebrospinal fluid measures of the microtubule binding region of tau (MTBR-tau) species that reflect tau aggregation could provide fluid biomarkers that track Alzheimer's disease related neurofibrillary ...
  • Evaluation of Baculoviruses as Gene Therapy Vectors for Brain Cancer 
    García Fallit, Matías; Pidre, Matías L.; Asad, Antonela S.; Peña Agudelo, Jorge A.; Vera, Mariana Belén; Nicola Candia, Alejandro J.; Sagripanti, Sofia B.; Pérez Küper, Melanie; Amorós Morales, Leslie C.; Marchesini, Abril; Gonzalez, Nazareno; Caruso, Carla M.; Romanowski, Víctor; Seilicovich, Adriana; Videla Richardson, Guillermo Agustín; Zanetti, Flavia A.; Candolfi, Marianela (MDPI, 2023-02-22)
    We aimed to assess the potential of baculoviral vectors (BV) for brain cancer gene therapy. We compared them with adenoviral vectors (AdV), which are used in neuro-oncology, but for which there is pre-existing immunity. ...
  • Abnormal brain network community structure related to psychological stress in schizophrenia 
    Castro, Mariana Nair; Bocaccio, Hernán; De Pino, Gabriela; Sánchez, Stella Maris; Wainsztein, Agustina Edith; Drucaroff, Lucas Javier; Costanzo, Elsa; Crossley, Nicolas; Mirta Fabiana, Villarreal; Guinjoan, Salvador Martín (Elsevier, 2023-02-15)
    Recent functional imaging studies in schizophrenia consistently report a disruption of brain connectivity. However, most of these studies analyze the brain connectivity during resting state. Since psychological stress is ...
  • Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study 
    Boerwinkle, Anna H.; Gordon, Brian A.; Wisch, Julie K.; Flores, Shaney; Henson, Rachel L.; Butt, Omar H.; McKay, Nicole S.; Chen, Charles D.; Benzinger, Tammie L.S.; Fagan, Anne M.; Handen, Benjamin L.; Christian, Bradley T.; Head, Elizabeth; Mapstone, Mark; Rafii, Michael S.; Alzheimer's Biomarker Consortium-Down Syndrome; Dominantly Inherited Alzheimer Network; Allegri, Ricardo Francisco; Chrem Méndez, Patricio Alexis; Egido, Noelia (Elsevier, 2022-12-12)
    Background: Important insights into the early pathogenesis of Alzheimer's disease can be provided by studies of autosomal dominant Alzheimer's disease and Down syndrome. However, it is unclear whether the timing and spatial ...
  • Autosomal dominant and sporadic late onset Alzheimer's disease share a common in vivo pathophysiology 
    Morris, John C.; Weiner, Michael W.; Xiong, Chengjie; Beckett, Laurel A.; Coble, Dean; Saito, Naomi; Aisen, Paul S.; Allegri, Ricardo Francisco; Benzinger, Tammie L.S.; Berman, Sarah B.; Cairns, Nigel; Carrillo, María C.; Chui, Helena C.; Chhatwal, Jasmeer P.; Cruchaga, Carlos; Fagan, Anne M.; Farlow, Martin R.; Fox, Nick C.; Ghetti, Bernardino; Goate, Alison M. (Oxford University Press, 2022-10-21)
    The extent to which the pathophysiology of autosomal dominant Alzheimer's disease corresponds to the pathophysiology of 'sporadic' late onset Alzheimer's disease is unknown, thus limiting the extrapolation of study findings ...
  • A critical pathway in human development: C19MC micrornas regulates FGF2 response in a model of human pluripotent stem cells cardiac differentiation 
    Möbbs, Alan Miqueas; Garate, Ximena; Scarafía, María Agustina; Colli, Carolina; Moro, Lucía Natalia; Luzzani, Carlos Daniel; Waisman, Ariel; La Greca, Alejandro; Miriuka, Santiago Gabriel (Fundación Revista Medicina, 2021-11)
  • Addressing the disparities in dementia risk, early detection and care in Latino populations: Highlights from the second Latinos & Alzheimer's Symposium 
    Quiroz, Yakeel T.; Solis, Michele; Aranda, María P.; Arbaje, Alicia I.; Arroyo-Miranda, Mirna; Cabrera, Laura Y.; Carrasquillo, Minerva Maria; Corrada, Maria M.; Crivelli, Lucía; Diminich, Erica D.; Dorsman, Karen A.; Gonzales, Mitzi; González, Héctor M.; Gonzalez-Seda, Ana L.; Grinberg, Lea T.; Guerrero, Lourdes R.; Hill, Carl V.; Jiménez Velázquez, Ivonne; Llibre Guerra, Jorge J.; Lopera, Francisco (John Wiley & Sons, 2022-09)
    The Alzheimer's Association hosted the second Latinos & Alzheimer's Symposium in May 2021. Due to the COVID-19 pandemic, the meeting was held online over 2 days, with virtual presentations, discussions, mentoring sessions, ...
  • First presentation with neuropsychiatric symptoms in autosomal dominant Alzheimer's disease: the Dominantly Inherited Alzheimer's Network Study 
    O'Connor, Antoinette; Rice, Helen; Barnes, Josephine; Ryan, Natalie S.; Liu, Kathy Y.; Allegri, Ricardo Francisco; Berman, Sarah B.; Ringman, John M.; Cruchaga, Carlos; Farlow, Martin R.; Hassenstab, Jason; Lee, Jae-Hong; Perrin, Richard J.; Xiong, Chengjie; Gordon, Brian A.; Levey, Allan I.; Goate, Alison M.; Graff-Radford, Neill R.; Levin, Johannes; Dominantly Inherited Alzheimer Network (BMJ Publishing Group, 2022-12-15)
  • Simple Microcontact Printing Technique to Obtain Cell Patterns by Lithography Using Grayscale, Photopolymer Flexographic Mold, and PDMS 
    Gimenez, Rocio; Pérez-Sosa, Camilo; Bourguignon, Natalia; Miriuka, Santiago Gabriel; Bhansali, Shekhar; Arroyo, Carlos R.; Debut, Alexis; Lerner, Betiana; Pérez, Maximiliano S. (MDPI AG, 2022-10-08)
    Microcontact printing using PDMS embossing tools and its variations have aroused the interest of a wide spectrum of research fields, hence the feasibility of defining micro and nanoscale patterns. In this work, we have ...
  • Improvement of episodic memory retention by a memory reactivation intervention across the lifespan: from younger adults to amnesic patients 
    Fernández, Rodrigo Sebastián; Picco, Soledad; Beron, Juan Cruz; Bavassi, Luz; Campos, Jorge; Allegri, Ricardo Francisco; Pedreira, María Eugenia (Nature Pub. Group, 2022-04-05)
    Spontaneous reactivation of recently acquired memories is a fundamental mechanism of memory stabilization. Re-exposure to specific learned cues during sleep or awake states, namely targeted memory reactivation, has been ...
  • Oculomotor Abnormalities during Reading in the Offspring of Late-Onset Alzheimer's Disease 
    Fernández, Gerardo; González, Ana Paula; Abulafia, Carolina; Fiorentini, Leticia; Agamennoni, Osvaldo; Guinjoan, Salvador Martín (Bentham Science Publishers, 2022)
    Introduction: Eye movement patterns during reading are well defined and documented. Each eye movement ends up in a fixation point, which allows the brain to process the incoming information and program the following saccade. ...
  • Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid 
    Drieu, Antoine; Du, Siling; Storck, Steffen E.; Rustenhoven, Justin; Papadopoulos, Zachary; Dykstra, Taitea; Zhong, Fenghe; Kim, Kyungdeok; Blackburn, Susan; Mamuladze, Tornike; Harari, Oscar; Karch, Celeste M.; Bateman, Randall J.; Perrin, Richard J.; Farlow, Martin R.; Chhatwal, Jasmeer P.; Dominantly Inherited Alzheimer Network; Hu, Song; Randolph, Gwendalyn J.; Allegri, Ricardo Francisco (Nature Publishing Group, 2022-11)
    Macrophages are important players in the maintenance of tissue homeostasis1. Perivascular and leptomeningeal macrophages reside near the central nervous system (CNS) parenchyma2, and their role in CNS physiology has not ...
  • Changes in cognitive functioning after COVID-19: A systematic review and meta-analysis 
    Crivelli, Lucía; Palmer, Katie; Calandri, Ismael Luis; Guekht, Alla; Beghi, Ettore; Carroll, William; Frontera, Jennifer; García-Azorín, David; Westenberg, Érica; Winkler, Andrea Sylvia; Mangialasche, Francesca; Allegri, Ricardo Francisco; Kivipelto, Miia (2022-05)
    Introduction: We conducted a systematic review and meta-analysis of the cognitive effects of coronavirus disease 2019 (COVID-19) in adults with no prior history of cognitive impairment. Methods: Searches in Medline/Web ...
  • Religiosity/Spirituality and Mental Health in Older Adults: A Systematic Review and Meta-Analysis of Observational Studies 
    Coelho-Júnior, Hélio José; Calvani, Riccardo; Panza, Francesco; Allegri, Ricardo Francisco; Picca, Anna; Marzetti, Emanuele; Alves, Vicente Paulo (Frontiers Media S.A., 2022-05)
    Objectives: The present study investigated the association between religious and spiritual (RS) practices with the prevalence, severity, and incidence of mental health problems in older adults. Methods: We conducted a ...
  • Towards imaging criteria that best differentiate MS from NMOSD and MOGAD: Large multi-ethnic population and different clinical scenarios 
    Carnero Contentti, Edgar; Rojas, Juan Ignacio; Criniti, Juan; López, Pablo Adrián; Daccach Marques, Vanessa; Soto de Castillo, Ibis; Tkachuk, Verónica A.; Marrodán, Mariano; Correale, Jorge; Farez, Mauricio Franco; Jin Kim, Ho; Hyun, Jae-Won; Messina, Silvia; Mariano, Romina; Rocca, Maria A.; Cacciaguerra, Laura; Filippi, Massimo; Palace, Jacqueline; Juryńczyk, Maciej (Elsevier B. V., 2022-05)
    Background: The "1/3″ brain magnetic resonance imaging (MRI) criteria including 1) a lesion adjacent to the lateral ventricle and in the inferior temporal lobe, or 2) a juxtacortical lesion, or 3) a Dawson finger-type ...
  • A neurodegenerative disease landscape of rare mutations in Colombia due to founder effects 
    Acosta-Uribe, Juliana; Aguillón, David; Cochran, J. Nicholas; Giraldo, Margarita; Madrigal, Lucía; Killingsworth, Bradley W.; Singhal, Rijul; Labib, Sarah; Alzate, Diana; Velilla, Lina M.; Moreno, Sonia; García, Gloria P.; Saldarriaga, Amanda; Piedrahita, Francisco; Hincapié, Liliana; López, Hugo E.; Perumal, Nithesh; Surace, Ezequiel Ignacio; Itzcovich, Tatiana; Allegri, Ricardo Francisco (BioMed Central, 2022-03-08)
    Background: The Colombian population, as well as those in other Latin American regions, arose from a recent tri-continental admixture among Native Americans, Spanish invaders, and enslaved Africans, all of whom passed ...
  • Neurosciences and Neuro post-COVID-19 
    Allegri, Ricardo Francisco; Román, Fabián; Barceló Martínez, Ernesto (Universidad de la Costa, 2021-03-23)
    Editorial
  • Transient Global Amnesia Recurrence: Prevalence and Risk Factor Meta-analysis 
    Hernández, Micaela Anahí; Arena, Julieta E.; Alessandro, Lucas; Allegri, Ricardo Francisco; Calandri, Ismael Luis (Lippincott Williams & Wilkins, 2022-08)
    Background and objectives: Transient global amnesia (TGA) is an acute amnestic disorder with unclear pathophysiology. Although considered a benign phenomenon, the possibility of a recurrence is a major concern for the ...
  • Latin America has been under-represented in dementia clinical trials, we must turn the corner 
    Allegri, Ricardo Francisco; Román, Fabián; Barceló Martínez, Ernesto (Universidad de la Costa, 2022-06-11)
    The world’s population is aging, life expectancy is increasing in the past century as result of the improvements in healthcare and the people arrive to live longer and healthier. However, this has also resulted in increase ...
  • Consecuencias Neurológicas y Psiquiátricas a largo plazo (6 meses) en pacientes con COVID leve de la comunidad 
    Allegri, Ricardo Francisco; Calandri, Ismael Luis; Caride, Alejandro; Román, Fabián; Llera, J.; Palma, A.; Bartoloni, L.; Carozzela, A.; González Sanz, P.; Mouchet, E.; Fernández Díaz, Paula C.; Morasso, C.; Tarulla, Adriana (Universidad de la Costa, 2022-06-08)
    Las complicaciones neurológicas a largo plazo de la infección por coronavirus han sido descriptas en los pacientes hospitalizados en el episodio agudo. De ellos el 63% presentaron fatiga y debilidad muscular, el 26% ...

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