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Multinodular and Vacuolating Neuronal Tumor of the Cerebrum (MVNT): A case series and review of the literature

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dc.contributor.author Buffa, Geraldine Belén
dc.contributor.author Chaves, Hernán
dc.contributor.author Serra, María Mercedes
dc.contributor.author Stefanoff, Nadia Ivanna
dc.contributor.author Gagliardo Cadena, Allan Salvatore
dc.contributor.author Yáñez, Paulina
dc.date.accessioned 2019-10-29T18:37:24Z
dc.date.available 2019-10-29T18:37:24Z
dc.date.issued 2020-05-01
dc.identifier.citation Buffa, G.B., Chaves, H., Serra, M.M., Stefanoff, N.I., Gagliardo, A.S., Yañez, P., 2020. Multinodular and Vacuolating Neuronal Tumor of the Cerebrum (MVNT): A case series and review of the literature. J Neuroradiol 47, 216–220. https://doi.org/10.1016/j.neurad.2019.05.010 en_US
dc.identifier.uri https://doi.org/10.1016/j.neurad.2019.05.010
dc.identifier.uri https://repositorio.fleni.org.ar/handle/123456789/88
dc.description.abstract BACKGROUND AND PURPOSE: Multinodular and Vacuolating Neuronal Tumor of the cerebrum (MVNT) is a benign -seizure associated- lesion affecting mostly adults. This new entity has been included in the 2016 World Health Organization classification of tumors of the central nervous system. Its pathologic hallmark consist of a subcortical cluster of nodular lesions located on the subcortical white matter. We aim to report a series of cases of presumed MVNT observed in our institution and review the literature. MATERIALS AND METHODS: In this retrospective study, a search was performed on our hospital information system. Sixteen cases were included. Demographic, clinical and radiological features were detailed in a table. All patients had an MRI acquired either on a 1.5 or a 3 Tesla scanner. Sequences performed included T1, T2, GRE/SWI, T2 FLAIR and DWI. Gadolinium enhanced T1-WI wer available in 11 patients and follow-up MRI were available in 7 patients. RESULTS: Patient ages ranged from 16 to 77 years (mean 42 years). Seizure and non-focal headache were by far the most common neurological complaints for which MRI was requested. All lesions consisted of clusters of multiple, discrete, round or ovoid, intra-axial, FLAIR and T2-WI hyperintense nodules. Follow-up MRI scans showed no changes between studies. CONCLUSIONS: MVNT is a benign, stable lesion that exhibits a typical radiological pattern that most of the times sufficed to arrive to a diagnosis, without the need of pathological confirmation. We confirm that our demographic, clinical and radiological findings are in accordance with those published in international literature. en_US
dc.language.iso eng en_US
dc.publisher Masson en_US
dc.rights info:eu-repo/semantics/openAccess
dc.rights.uri https://creativecommons.org/licenses/by/2.5/ar/
dc.subject Epilepsy en_US
dc.subject Epilepsia en_US
dc.subject Magnetic Resonance Imaging en_US
dc.subject Imagen por Resonancia Magnética en_US
dc.subject Seizures en_US
dc.subject Convulsiones en_US
dc.subject Neoplasms en_US
dc.subject Neoplasias en_US
dc.title Multinodular and Vacuolating Neuronal Tumor of the Cerebrum (MVNT): A case series and review of the literature en_US
dc.type info:eu-repo/semantics/publishedVersion
dc.type info:eu-repo/semantics/article en_US
dc.description.fil Fil: Buffa, Geraldine Belén. Fleni. Departamento de Diagnóstico por Imágenes; Argentina.
dc.description.fil Fil: Chaves, Hernán. Fleni. Departamento de Diagnóstico por Imágenes; Argentina.
dc.description.fil Fil: Serra, María Mercedes. Fleni. Departamento de Diagnóstico por Imágenes; Argentina.
dc.description.fil Fil: Stefanoff, Nadia Ivanna. Fleni. Departamento de Diagnóstico por Imágenes; Argentina.
dc.description.fil Fil: Gagliardo Cadena, Allan Salvatore. Fleni. Departamento de Diagnóstico por Imágenes; Argentina.
dc.description.fil Fil: Yañez, Paulina. Fleni. Departamento de Diagnóstico por Imágenes; Argentina.
dc.relation.ispartofVOLUME 47
dc.relation.ispartofNUMBER 3
dc.relation.ispartofPAGINATION 16-220.
dc.relation.ispartofCOUNTRY Francia
dc.relation.ispartofCITY Paris
dc.relation.ispartofTITLE Journal of neuroradiology
dc.relation.ispartofISSN 0150-9861
dc.type.snrd info:ar-repo/semantics/artículo es_ES


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