Repositorio Institucional FLENI: Recent submissions

  • Espectroscopía in vivo por resonancia magnética : Capacidad de un resonador clínico de 1.5 Teslas de estimar grado de malignidad de tumores por espectroscopía 
    Calvar, Jorge Andrés (2000)
  • Identificación de biomarcadores del estrés usando correlaciones espaciales y temporales de las actividades cerebral y periférica del sistema nervioso humano 
    Álvarez Mercé, Rocío (2017)
    Los equipos de resonancia magnética nuclear de uso clínico permiten registrar imágenes de la actividad cerebral ante estímulos o tareas pautadas. Muchas veces, dado el alto grado de subjetividad del proceso mental a estudiar, ...
  • Remyelinating effect driven by transferrin-loaded extracellular vesicles 
    Mattera, Vanesa S.; Occhiuzzi, Federico; Correale, Jorge; Pasquini, Juana María (Wiley, 2023-10-20)
    Extracellular vesicles (EVs) are involved in diverse cellular functions, playing a significant role in cell-to-cell communication in both physiological conditions and pathological scenarios. Therefore, EVs represent a ...
  • Hipofisitis primaria: diagnóstico y tratamiento. Estudio multicéntrico 
    Tkatch, Julieta; Szuman, Gabriela; Agüero, Mónica; Alfieri, Analía; Ballarino, María Carolina; Bamberger, Elizabeth; Battistone, María Florencia; Boero, Laura; Danilowicz, Karina; Donoso, Marina; Fainstein Day, Patricia; Furioso, Alejandra; Glerean, Mariela; González Pernas, Mariana Soledad; Guitelman, Mirtha; Katz, Débora Adela; Loto, Mónica; Pignatta, Analía; Slavinsky, Patricia; Sosa, Soledad (Fundación Revista Medicina, 2023-06-06)
    Introducción: La hipofisitis es una enfermedad infrecuente que plantea un desafío en el diagnóstico y tratamiento. El objetivo de este estudio multicéntrico y retrospectivo fue describir: a) características de pacientes ...
  • Ataxias espinocerebelosas de herencia autosómica dominante: nueva clasificación clínica y desarrollo de una herramienta informática para la orientación y predicción diagnóstica 
    Rossi, Malco Damián (2016)
    Introducción: Las ataxias espinocerebelosas (SCA) son un grupo de trastornos neurodegenerativos y heterogéneos desde el punto de vista clínico y genético que se caracterizan por la presencia de ataxia progresiva como ...
  • Mortality of neuromyelitis optica spectrum disorder patients in an Argentinean population: A study from the RelevarEM registry 
    Carnero Contentti, Edgar; López, Pablo Adrián; Pettinicchi, Juan Pablo; Criniti, Juan; Pappolla, Agustín; Miguez, Jimena; Cristiano, Edgardo; Patrucco, Liliana; Liwacki, Susana; Tkachuk, Verónica A.; Balbuena Aguirre, María Eugenia; Vrech, Carlos; Deri, Norma; Correale, Jorge; Marrodán, Mariano; Ysrraelit, María Célica; Leguizamon, Felisa; Luetic, Geraldine G.; Menichini, María Laura; Tavolini, Darío (Sage, 2023-10-17)
    We aimed to evaluate mortality and causes of death among Argentinean neuromyelitis optica spectrum disorder (NMOSD) patients and identify predictors of death. Retrospective study included 158 NMOSD patients and 11 (7%) ...
  • Longitudinal clinical, cognitive and biomarker profiles in dominantly inherited versus sporadic early-onset Alzheimer's disease 
    Llibre Guerra, Jorge J.; Iaccarino, Leonardo; Coble, Dean; Edwards, Lauren; Li, Yan; McDade, Eric; Strom, Amelia; Gordon, Brian A.; Mundada, Nidhi; Schindler, Suzanne E.; Tsoy, Elena; Ma, Yinjiao; Lu, Ruijin; Fagan, Anne M.; Benzinger, Tammie L.S.; Soleimani Meigooni, David; Aschenbrenner, Andrew J.; Allegri, Ricardo Francisco; Patricio Alexis, Chrem Méndez; Surace, Ezequiel Ignacio (Oxford University Press, 2023-10-18)
    Approximately 5% of Alzheimer's disease cases have an early age at onset (<65 years), with 5-10% of these cases attributed to dominantly inherited mutations and the remainder considered as sporadic. The extent to which ...
  • Risk factors for respiratory failure among hospitalized patients with Guillain-Barré syndrome 
    Maskin, Luis Patricio; Wilken, Miguel; Rodríguez Lucci, Federico; Wisnivesky, J. P.; Barroso, Fabio Adrián; Wainsztein, Néstor Adrián (Elsevier España, 2024-02)
    Background: Guillain-Barré syndrome (GBS) is an acute inflammatory polyneuropathy that can lead to respiratory failure. In this study, we evaluate early clinical risk factors for respiratory failure at the time of hospital ...
  • Persistence of Basal Ganglia Oscillatory Activity During Tremor Attenuation by Movement in Parkinson's Disease Patients 
    Wilken, Miguel; Andrés, Daniela S.; Bianchi, Gianfranco; Hallett, Mark; Merello, Marcelo (Wiley, 2024-02-28)
    Background: One of the characteristics of parkinsonian tremor is that its amplitude decreases with movement. Current models suggest an interaction between basal ganglia (BG) and cerebello-thalamo-cortical circuits in ...
  • Transoperative Magnetic Resonance Imaging in awake glioma surgery: Experience in a Latin American tertiary-level center 
    Ruella, Mauro; Caffaratti, Guido; Chaves, Hernán; Yañez, Paulina; Cervio, Andrés Eduardo (Elsevier, 2024-02-28)
    Objective: Analyze the usefulness, efficacy, and safety of transoperative Magnetic Resonance Imaging in glioma surgery in awake patients. Materials and methods: Retrospective, single-center, analytical study of a cohort ...
  • Evaluation and treatment approaches for neurological post-acute sequelae of COVID-19: A consensus statement and scoping review from the global COVID-19 neuro research coalition 
    Frontera, Jennifer; Guekht, Alla; Allegri, Ricardo Francisco; Ashraf, Mariam; Baykan, Betül; Crivelli, Lucía; Easton, Ava; Garcia-Azorin, David; Helbok, Raimund; Joshi, Jatin; Koehn, Julia; Koralnik, Igor; Netravathi, M.; Benedict, Michael; Nilo, Annacarmen; Özge, Aynur; Padda, Karanbir; Pellitteri, Gaia; Prasad, Kameshwar; Romozzi, Marina (Elsevier, 2023-11-15)
    Post-acute neurological sequelae of COVID-19 affect millions of people worldwide, yet little data is available to guide treatment strategies for the most common symptoms. We conducted a scoping review of PubMed/Medline ...
  • Establishing an online resource to facilitate global collaboration and inclusion of underrepresented populations: Experience from the MJFF Global Genetic Parkinson's Disease Project 
    Vollstedt, Eva-Juliane; Madoev, Harutyun; Aasly, Anna; Ahmad-Annuar, Azlina; Al-Mubarak, Bashayer; Alcalay, Roy N.; Alvarez, Victoria; Amorin, Ignacio; Annesi, Grazia; Arkadir, David; Bardien, Soraya; Barker, Roger A.; Barkhuizen, Melinda; Basak, A. Nazli; Bonifati, Vincenzo; Boon, Agnita; Brighina, Laura; Brockmann, Kathrin; Belin, Andrea Carmine; Merello, Marcelo (Public Library of Science, 2023-10-03)
    Parkinson's disease (PD) is the fastest-growing neurodegenerative disorder, currently affecting ~7 million people worldwide. PD is clinically and genetically heterogeneous, with at least 10% of all cases explained by a ...
  • Predictors and Pathophysiology of Axial Postural Abnormalities in Parkinsonism: A Scoping Review 
    Artusi, Carlo Alberto; Geroin, Christian; Nonnekes, Jorik; Aquino, Camila; Garg, Divyani; Dale, Marian L.; Schlosser, Darbe; Lai, Yijie; Al-Wardat, Mohammad; Salari, Mehri; Wolke, Robin; Tsinda Labou, Valery; Imbalzano, Gabriele; Camozzi, Serena; Merello, Marcelo; Bloem, Bastiaan R.; Capato, Tamine; Djaldetti, Ruth; Doherty, Karen; International Parkinson and Movement Disorders Society Task Force on Postural Abnormalities (Wiley, 2023-09-06)
    Background: Postural abnormalities involving the trunk are referred to as axial postural abnormalities and can be observed in over 20% of patients with Parkinson's disease (PD) and in atypical parkinsonism. These symptoms ...
  • PluriBAC: A Versatile Baculovirus-Based Modular System to Express Heterologous Genes in Different Biotechnological Platforms 
    Amorós Morales, Leslie C.; Marchesini, Abril; Gómez Bergna, Santiago M.; García Fallit, Matías; Tongiani, Silvana E.; Vásquez, Larisa; Ferrelli, María Leticia; Videla Richardson, Guillermo Agustín; Candolfi, Marianela; Romanowski, Víctor; Pidre, Matías L. (MDPI, 2023-09-23)
    Baculoviruses are insect-specific pathogens widely used in biotechnology. In particular, the Autographa californica nucleopolyhedrovirus (AcMNPV) has been exploited as a platform for bio-inputs production. This is why the ...
  • Migraine in older adults 
    Hugger, Sarah Sonja; Do, Thien Phu; Ashina, Håkan; Goicochea, María Teresa; Jenkins, Bronwyn; Sacco, Simona; Lee, Mi Ji; Brennan, K. C.; Amin, Faisal Mohammad; Steiner, Timothy J.; Ashina, Messoud (Elsevier, 2023-09-20)
    Migraine is an evolving, and sometimes lifelong disorder. The prevalence of episodic migraine peaks among individuals aged in their late 30s, implying a tendency for the disorder to remit with increasing age thereafter, ...
  • Role of hydroxymethylglutharyl-coenzyme A reductase in the induction of stem-like states in breast cancer 
    Marks, María Paula; Giménez, Carla Alejandra; Isaja, Luciana; Vera, Mariana Belén; Borzone, Francisco Raúl; Pereyra-Bonnet, Federico; Romorini, Leonardo; Videla Richardson, Guillermo Agustín; Chasseing, Norma Alejandra; Calvo, Juan Carlos; Vellón, Luciano (Springer-Verlag, 2024-02-28)
    Purpose: De novo synthesis of cholesterol and its rate-limiting enzyme, 3-hydroxy-3-methylglutharyl-coenzyme A reductase (HMGCR), is deregulated in tumors and critical for tumor cell survival and proliferation. However, ...
  • Presenilin-1 mutation position influences amyloidosis, small vessel disease, and dementia with disease stage 
    Joseph-Mathurin, Nelly; Feldman, Rebecca L.; Lu, Ruijin; Shirzadi, Zahra; Toomer, Carmen; Saint Clair, Junie R.; Ma, Yinjiao; McKay, Nicole S.; Strain, Jeremy F.; Kilgore, Collin; Friedrichsen, Karl A.; Chen, Charles D.; Gordon, Brian A.; Chen, Gengsheng; Hornbeck, Russ C.; Massoumzadeh, Parinaz; McCullough, Austin; Wang, Qing; Li, Yan; Allegri, Ricardo Francisco; Dominantly Inherited Alzheimer Network (John Wiley & Sons, 2024-02-21)
    Introduction: Amyloidosis, including cerebral amyloid angiopathy, and markers of small vessel disease (SVD) vary across dominantly inherited Alzheimer's disease (DIAD) presenilin-1 (PSEN1) mutation carriers. We investigated ...
  • Therapeutic Potential in Wound Healing of Allogeneic Use of Equine Umbilical Cord Mesenchymal Stem Cells 
    Iribarne, Ailén; Palma, María Belén; Andrini, Laura B.; Riccillo, Fernando; Rodríguez, Delfina; Casella, Martín; Garay, Felipe; Spoto Zabala, Julieta; Mazza, Leandro; Muro, Adriana; Buero, Guillermo; Miriuka, Santiago Gabriel; Carosella, Edgardo D.; García, Marcela Nilda (MDPI, 2024-02-16)
    Wound healing after skin injury is a complex process, particularly in equines where leg wounds are prevalent and their repair is complicated due to the anatomical characteristics. Conventional treatments are not effective ...
  • Alzheimer's polygenic risk scores are associated with cognitive phenotypes in Down syndrome 
    Gorijala, Priyanka; Aslam, M. Muaaz; Dang, Lam-Ha T.; Xicota, L.; Fernández, María V.; Sung, Yun Ju; Fan, Kang-Hsien; Feingold, Eleanor; Surace, Ezequiel Ignacio; Chhatwal, Jasmeer P.; Hom, Christy L.; Dominantly Inherited Alzheimer Network; NIA-LOAD family study, for the Alzheimer's Biomarkers Consortium-Down Syndrome (ABC-DS) Investigators; Hartley, Sigan L.; Hassenstab, Jason; Perrin, Richard J.; Mapstone, Mark; Zaman, Shahid H.; Ances, Beau M.; Kamboh, M. Ilyas; Lee, Joseph H.; Cruchaga, Carlos (John Wiley & Sons, 2023-10-19)
    Introduction: This study aimed to investigate the influence of the overall Alzheimer's disease (AD) genetic architecture on Down syndrome (DS) status, cognitive measures, and cerebrospinal fluid (CSF) biomarkers. Methods: ...
  • The clinical and biochemical spectrum of ectopic acromegaly 
    Fainstein Day, Patricia; Ullmann, Tamara Estefanía; Dalurzo, Mercedes Corina Liliana; Sevlever, Gustavo Emilio; Smith, David Eduardo (Elsevier, 2024-02-14)
    Ectopic acromegaly is a rare condition caused by extrapituitary central or peripheral neuroendocrine tumours (NET) that hypersecrete GH or, more commonly, GHRH. It affects less than 1% of acromegaly patients and a misdiagnosis ...

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