Repositorio Institucional FLENI: Recent submissions

  • Neural and subjective effects of inhaled N,N-dimethyltryptamine in natural settings 
    Pallavicini, Carla; Cavanna, Federico; Zamberlan, Federico; de la Fuente, Laura A.; Ilksoy, Yayla; Perl, Yonatan Sanz; Arias, Mauricio; Romero, Celeste; Carhart-Harris, Robin; Timmermann, Christopher; Tagliazucchi, Enzo (Sage, 2021-02-10)
    Background: N,N-dimethyltryptamine is a short-acting psychedelic tryptamine found naturally in many plants and animals. Few studies to date have addressed the neural and psychological effects of N,N-dimethyltryptamine ...
  • Immunosuppressive Amino-Acid Catabolizing Enzymes in Multiple Sclerosis 
    Correale, Jorge (Frontiers Research Foundation, 2021-01-20)
    Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease that affects the central nervous system. Although the pathogenesis of MS is not yet fully elucidated, several evidences suggest that autoimmune processes ...
  • Limitations of the Unified Multiple System Atrophy Rating Scale as outcome measure for clinical trials and a roadmap for improvement 
    Palma, José Alberto; Millar Vernetti, Patricio; Perez, Miguel A.; Krismer, Florian; Seppi, Klaus; Fanciulli, Alessandra; Singer, Wolfgang; Low, Phillip; Biaggioni, Italo; Norcliffe-Kaufmann, Lucy; Pellecchia, Maria Teresa; Martí, Maria José; Kim, Han-Joon; Merello, Marcelo; Stankovic, Iva; Poewe, Werner; Betensky, Rebecca; Wenning, Gregor; Kaufmann, Horacio (Springer, 2021-02-07)
    Purpose The unified multiple system atrophy (MSA) rating scale (UMSARS) was developed almost 20 years ago as a clinical rating scale to capture multiple aspects of the disease. With its widespread use, the shortcomings ...
  • Bloqueo nervioso corticoideo-bupivacaína: ¿La mejoría post-procedimiento inmediato predice el éxito terapéutico a mediano plazo? 
    Cobeñas, Ricardo; Flórez, Juan; Chiaradia , Pablo; Ruiz Salgado, Kelly; De Vedia, María; Paba, Mariángela; Hernández Pinzón, Jairo (Thieme, 2021-02-04)
    Objetivo Establecer la relación entre la reducción inmediata de los síntomas post bloqueo nervioso lumbar guiado por tomografía computada (TC) y la mejoría tras un lapso de tiempo de un mes. Materiales y métodos Se ...
  • Structural brain abnormalities in schizophrenia in adverse environments: examining the effect of poverty and violence in six Latin American cities 
    Crossley, Nicolas; Zugman, Andre; Reyes-Madrigal, Francisco; Czepielewski, Leticia; Castro, Mariana Nair; Diaz-Zuluaga, Ana María; Pineda-Zapata, Julián; Reckziegel, Ramiro; Gadelha, Ary; Jackowski, Andrea; Noto, Cristiano; Alliende Serra, Luz Maria; Iruretagoyena, Bárbara; Ossandon, Tomas; Ramirez-Mahaluf, Juan Pablo; Castañeda, Carmen Paz; Gonzalez-Valderrama, Alfonso; Nachar, Rubén; Guinjoan, Salvador Martín; ANDES Network (Cambridge University Press, 2020-08-18)
    Background Social and environmental factors such as poverty or violence modulate the risk and course of schizophrenia. However, how they affect the brain in patients with psychosis remains unclear. Aims We studied how ...
  • Automatic and unbiased segmentation and quantification of myofibers in skeletal muscle 
    Waisman, Ariel; Norris, Alessandra; Costa, Martín Elías; Kopinke, Daniel (Nature Publishing Group, 2021-01-22)
    Skeletal muscle has the remarkable ability to regenerate. However, with age and disease muscle strength and function decline. Myofiber size, which is affected by injury and disease, is a critical measurement to assess ...
  • HLA-G gene editing: a novel therapeutic alternative in cancer immunotherapy 
    Palma, María Belén; Tronik-Le Roux, Diana; Amín, Guadalupe; Castañeda, Sheila; Möbbs, Alan Miqueas; Scarafía, María Agustina; La Greca, Alejandro; Daouya, Marina; Poras, Isabelle; Inda, Ana María; Moro, Lucía Natalia; Carosella, Edgardo D.; García, Marcela Nilda; Miriuka, Santiago Gabriel (bioRxiv, 2021-01-22)
    Cancer immunotherapies based mainly on the blockade of immune-checkpoint (IC) molecules by anti-IC antibodies offer new alternatives for treatment in oncological diseases. However, a considerable proportion of patients ...
  • Endocan, VEGF, FGF2 and PDGF Expression in Pituitary Tumors. A Precise Angiogenic Marker Relationship in the Context of Tumor Invasiveness 
    Tao, Pengyou; Perrone, Sofía; Demarchi, Gianina; Chimento, Agustina; Cervio, Andrés Eduardo; Sevlever, Gustavo Emilio; Berner, Silvia Inés; Becu-Villalobos, Damasia; Basso, Armando; Ge, Chen; Ling, Feng; Zhang, Qiuhang; Cristina, Carolina (Research Square, 2021-01-20)
    Background: Pituitary adenomas can become invasive and aggressive, and in turn produce tumor recurrence. Endocan or endothelial cell specific molecule-1 (ESM1) has been associated with angiogenesis and tumor growth in ...
  • Recomendaciones actualizadas para la profilaxis de la enfermedad tromboembólica venosa en Argentina 
    Vázquez, Fernando J.; Korin, Jorge; Baldessari, Enrique M.; Capparelli, Federico Javier; Gutierrez, Paula; Pale, Carlos; Bocanegra, Florencia; Grand, Beatriz; Vilaseca, Alicia; Penchasky, Diana; González Alcántara, María Mónica; Prémoli, María Sol; Tabares, Aldo; Wainsztein, Néstor Adrián; Odetto, Diego; Vaccaro, Carlos; Martínez Aquino, Eleno; Cumpian, Olga; Falabella, Verónica; García, Santiago Antuel; Saadi, José; Siccardi, Mariana; Gandara, Esteban (Fundación Revista Medicina (Buenos Aires), 2020-01)
    La enfermedad tromboembólica venosa (ETV) en adultos hospitalizados posee elevada morbimortalidad, es origen de complicaciones crónicas y determina incrementos de costos para el sistema de salud. Desde la publicación de ...
  • The prevalence of migraine in Argentina: A reappraisal 
    Lisicki, Marco; Figuerola, María L.; Bonamico, Lucas; Lew, Daniel; Goicochea, María Teresa (Sage, 2021-02-21)
    Background: Argentina has one of the largest territories in the world, which spreads over a lengthy latitudinal span. Its population is mainly composed of a mixture of South American natives and the descendants of numerous ...
  • Chronic abdominal aortic dissection, endovascular treatment using a new Stent-graft for in situ Fenestration 
    Bertoni, Hernán Gabriel; Girela, German A.; Barone, Hector D.; de Caso, Federico; de La Vega, Alejandro; Bui, Bao T.; Maldonado, Thomas (Springer, 2021-01-29)
    Background: Although endovascular treatment of the thoracic aorta (TEVAR) has become an elective procedure for treatment of complicated type B aortic dissection, its role in treating post dissection thoraco-abdominal aortic ...
  • Prediction of Balance After Inpatient Rehabilitation in Stroke Subjects with Severe Balance Alterations at the Admission 
    Gath, Christian Federico; Gianella, Matías Gabriel; Bonamico, Lucas; Olmos, Lisandro Emilio; Russo, María Julieta (Elsevier, 2021-01-25)
    Background: Patients with severe motor alterations would be those on who the prediction of the expected motor response after inpatient rehabilitation programs is most required. Objectives: To analyze if the balance ...
  • miR-302 family, miR-145 and miR-296 temporal expression profile along the cell cycle of human pluripotent stem cells 
    Rodríguez Varela, María Soledad; Mucci, Sofía; Videla Richardson, Guillermo Agustín; Isaja, Luciana; Sevlever, Gustavo Emilio; Scassa, María Élida; Romorini, Leonardo (Elsevier, 2021-01-21)
    Human pluripotent stem cells (hPSCs), like embryonic (hESCs) and induced pluripotent stem cells (hiPSCs), exhibit an unusual cell cycle structure characterized by a short G1 phase and cells being most of time in S phase. ...
  • Prior Heart Failure Hospitalization, Clinical Outcomes, and Response to Sacubitril/Valsartan Compared With Valsartan in HFpEF 
    Vaduganathan, Muthiah; Claggett, Brian L.; Desai, Akshay S.; Anker, Stefan D.; Perrone, Sergio Víctor; Janssens, Stefan; Milicic, Davor; Arango, Juan L.; Packer, Milton; Shi, Victor C.; Lefkowitz, Martin P.; McMurray, John J.V.; Solomon, Scott D. (Elsevier, 2020-01-28)
    Background: The period shortly after hospitalization for heart failure (HF) represents a high-risk window for recurrent clinical events, including rehospitalization or death. Objectives: This study sought to determine ...
  • Developmental and epileptic encephalopathy due to SZT2 genomic variants: Emerging features of a syndromic condition 
    Trivisano, Marina; Rivera, Manuel; Terracciano, Alessandra; Ciolfi, Andrea; Napolitano, Antonio; Pepi, Chiara; Calabrese, Costanza; Digilio, Maria Cristina; Tartaglia, Marco; Curatolo, Paolo; Vigevano, Federico; Specchio, Nicola (Academic Press, 2020-07)
    Seizure threshold 2 (SZT2) gene mutations have been associated with developmental and epileptic encephalopathies (DEEs). Following a literature review, we collected 22 patients and identified the main clinical features ...
  • Impaired brain glucose metabolism and presynaptic dopaminergic functioning in a mouse model of schizophrenia 
    Tomasella, Eugenia; Falasco, Germán; Urrutia, Leandro; Bechelli, Lucila; Padilla, Lucia; Gelman, Diego M. (Springer, 2020-03-17)
    Background: Schizophrenia is a disease diagnosed by visible signs and symptoms from late adolescence to early adulthood. The etiology of this disease remains unknown. An objective diagnostic approach is required. Here, we ...
  • Heart rate variability and falls in Huntington's disease 
    Terroba Chambi, Cinthia; Bruno, Verónica; Vigo, Daniel Eduardo; Merello, Marcelo (Rapid Communications of Oxford, 2020-02-06)
    Purpose: Persons with Huntington's disease (HD) have a high incidence of falls. Autonomic nervous system dysfunction has been reported even in early stages of this disease. To date, there has been no analysis of the ...
  • Longitudinal Accumulation of Cerebral Microhemorrhages in Dominantly Inherited Alzheimer Disease 
    Joseph-Mathurin, Nelly; Wang, Guoqiao; Kantarci, Kejal; Jack Jr, Clifford R.; McDade, Eric; Hassenstab, Jason; Blazey, Tyler M.; Gordon, Brian A.; Su, Yi; Chen, Gengsheng; Massoumzadeh, Parinaz; Hornbeck, Russ C.; Allegri, Ricardo Francisco; Ances, Beau M.; Berman, Sarah B.; Brickman, Adam M.; Brooks, William S.; Cash, David M.; Chhatwal, Jasmeer P.; Dominantly Inherited Alzheimer Network (AAN, 2021-01-25)
    Objective: To investigate the inherent clinical risks associated with the presence of cerebral microhemorrhages (CMHs) or cerebral microbleeds (CMBs) and characterize individuals at high risk for developing hemorrhagic ...
  • Movement Disorders in the World of COVID-19 
    Stoessl, A Jon; Bhatia, Kailash P.; Merello, Marcelo (Wiley, 2020-04-16)
    Resumen no disponible
  • Prevalence of C9orf72 hexanucleotide repeat expansion in Greek patients with sporadic ALS 
    Sokratous, Maria; Schottlaender, Lucía V.; Bourinaris, Thomas; Marogianni, Chrysoula; Arnaoutoglou, Marianthi; Patrikiou, Eleni; Ralli, Styliani; Markou, Aikaterini; Dardiotis, Efthimios; Houlden, Henry; Hadjigeorgiou, Georgios M.; Xiromerisiou, Georgia (Taylor & Francis, 2020-07)
    A total of 178 consecutive patients with definite sALS without frontotemporal dementia (FTD) were enrolled in this study, after complete clinical evaluation. A Repeat-Primed Polymerase Chain Reaction (RP-PCR) protocol was ...

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