Repositorio Institucional FLENI: Recent submissions

  • Task Force Consensus on Nosology and Cut-Off Values for Axial Postural Abnormalities in Parkinsonism 
    Tinazzi, Michele; Geroin, Christian; Bhidayasiri, Roongroj; Bloem, Bastiaan R.; Capato, Tamine; Djaldetti, Ruth; Doherty, Karen; Fasano, Alfonso; Tibar, Houyam; Lopiano, Leonardo; Margraf, Nils G.; Merello, Marcelo; Moreau, Caroline; Ugawa, Yoshikazu; Artusi, Carlo Alberto; International Parkinson and Movement Disorders Society Task Force on Postural Abnormalities (Wiley, 2022-05-09)
    Background:There is no consensus with regard to the nosology and cut-off values for posturalabnormalities in parkinsonism.ObjectiveObjective:To reach a consensus regarding the nosology and cut-off values.MethodsMethods:Using ...
  • Predicting Outcome in Guillain-Barré Syndrome: International Validation of the Modified Erasmus GBS Outcome Score 
    Doets, Alex Y.; Lingsma, Hester F.; Walgaard, Christa; Islam, Badrul; Papri, Nowshin; Davidson, Amy; Yamagishi, Yuko; Kusunoki, Susumu; Dimachkie, Mazen M.; Waheed, Waqar; Kolb, Noah; Islam, Zhahirul; Deen Mohammad, Quazi; Harbo, Thomas; Sindrup, Soren H.; Chavada, Govindsinh; Willison, Hugh J.; Casasnovas, Carlos; Barroso, Fabio Adrián; IGOS consortium (Lippincott Williams & Wilkins, 2021-12-22)
    Background and objectives: The clinical course and outcome of the Guillain-Barré syndrome (GBS) are diverse and vary among regions. The modified Erasmus GBS Outcome Score (mEGOS), developed with data from Dutch patients, ...
  • A quadratic linear-parabolic model-based EEG classification to detect epileptic seizures 
    Quintero Rincón, Antonio; D'Giano, Carlos; Batatia, Hadj (Editorial Department of the Journals of Nanjing Medical University, 2019-08-28)
    The two-point central difference is a common algorithm in biological signal processing and is particularly useful in analyzing physiological signals. In this paper, we develop a model-based classification method to detect ...
  • Clinical and demographic characteristics of male MS patients included in the national registry-RelevarEM. Does sex or phenotype make the difference in the association with poor prognosis? 
    Luetic, Geraldine G.; Menichini, María Laura; Vrech, Carlos; Pappolla, Agustín; Patrucco, Liliana; Cristiano, Edgardo; Marrodán, Mariano; Ysrraelit, María Célica; Fiol, Marcela Paula; Correale, Jorge; Cohen, Leila; Alonso, Ricardo; Silva, Berenice Anabel; Casas, Magdalena; Garcea, Orlando; Deri, Norma; Burgos, Marcos; Liwacki, Susana; Tkachuk, Verónica A.; Barboza, Andrés G. (Elsevier, 2021-11-17)
    Background In multiple sclerosis demographics there is a well-known female prevalence and male patients have been less specifically evaluated in clinical studies, though some clinical differences have been reported between ...
  • Guía de práctica clínica: tratamiento sintomático de esclerosis múltiple. Grupo de Trabajo de Enfermedades Desmielinizantes. Sociedad Neurológica Argentina 
    Barboza, Andrés G.; Sinay, Vladimiro; Zanga, Gisela; Alonso, Ricardo; Silva, Berenice Anabel; Saladino, María Laura; Cohen, Leila; Luetic, Geraldine G.; Camerlingo, S.; Ysrraelit, María Célica; Tenembaum, S. N.; Tarulla, Adriana; Carnero Contentti, Edgar; López, Pablo Adrián; Pita, Cecilia; Tavolini, Darío; Steinberg, Judith; Menichini, María Laura; Rojas, Juan Ignacio; Tizio, Santiago (Elsevier, 2022-06-18)
    Introducción El tratamiento sintomático en la esclerosis múltiple (EM) representa uno de los pilares del abordaje global de esta patología. El tratamiento específico de los síntomas tiene como objetivo reducir o eliminar ...
  • Magnetothermal Neurostimulation: A Minimally Invasive and "Wireless" Alternative for Deep Brain Stimulation in Movement Disorders? 
    Castillo Torres, Sergio Andrés; Páez Maggio, Mauricio (Wiley, 2022-03-01)
  • Clinical and genetic profile of patients enrolled in the Transthyretin Amyloidosis Outcomes Survey (THAOS): 14-year update 
    Dispenzieri, Angela; Coelho, Teresa; Conceição, Isabel; Waddington Cruz, Marcia; Wixner, Jonas; Kristen, Arnt V.; Rapezzi, Claudio; Planté-Bordeneuve, Violaine; Gonzalez-Moreno, Juan; Maurer, Mathew S.; Grogan, Martha; Chapman, Doug; Amass, Leslie; Barroso, Fabio Adrián; THAOS investigators (BioMed Central, 2022-06-18)
    Background: Transthyretin amyloidosis (ATTR amyloidosis) is a rare, life-threatening disease caused by the accumulation of variant or wild-type (ATTRwt amyloidosis) transthyretin amyloid fibrils in the heart, peripheral ...
  • Predicting brain age from functional connectivity in symptomatic and preclinical Alzheimer disease 
    Millar, Peter R.; Luckett, Patrick H.; Gordon, Brian A.; Benzinger, Tammie L.S.; Schindler, Suzanne E.; Fagan, Anne M.; Cruchaga, Carlos; Bateman, Randall J.; Allegri, Ricardo Francisco; Jucker, Mathias; Lee, Jae-Hong; Mori, Hiroshi; Salloway, Stephen; Igor, Yakushev; Morris, John C.; Ances, Beau M.; Dominantly Inherited Alzheimer Network (Academic Press, 2022-08-01)
    "Brain-predicted age" quantifies apparent brain age compared to normative neuroimaging trajectories. Advanced brain-predicted age has been well established in symptomatic Alzheimer disease (AD), but is underexplored in ...
  • Métodos de cuantificación cerebral con ROI´s a partir de imágenes de Resonancia Magnética y 18F-FDG en sujetos con distribución normal 
    Castellano, Fernando Ariel (2020-08)
    La evaluación del metabolismo cerebral en los estudios de Tomografía por Emisión de Positrones (PET, por sus siglas en inglés) con 18F-FDG se realiza tradicionalmente de manera cualitativa a partir de una inspección visual ...
  • Unifying turbulent dynamics framework distinguishes different brain states 
    Escrichs, Anira; Sanz Perl, Yonatan; Uribe, Carme; Camara, Estela; Türker, Basak; Pyatigorskaya, Nadya; López-González, Ane; Pallavicini, Carla; Panda, Rajanikant; Annen, Jitka; Gosseries, Olivia; Laureys, Steven; Naccache, Lionel; Sitt, Jacobo D.; Laufs, Helmut; Tagliazucchi, Enzo; Kringelbach, Morten; Deco, Gustavo (Nature Publishing Group UK, 2022-05-29)
    Significant advances have been made by identifying the levels of synchrony of the underlying dynamics of a given brain state. This research has demonstrated that non-conscious dynamics tend to be more synchronous than in ...
  • Accuracy of Central Neuro-Imaging Review of DIPG Compared with Histopathology in the International DIPG Registry 
    Lazow, Margot A.; Fuller, Christine; DeWire-Schottmiller, Mariko; Lane, Adam; Bandopadhayay, Pratiti; Bartels, Ute; Bouffet, Eric; Cheng, Sylvia; Cohen, Kenneth J.; Cooney, Tabitha M.; Coven, Scott L.; Dholaria, Hetal; Diez, Blanca; Dorris, Kathleen; El-Ayadi, Moatasem; El-Sheikh, Ayman; Fisher, Paul G.; Fonseca, Adriana; Garcia Lombardi, Mercedes; Sevlever, Gustavo Emilio (Oxford, 2021-10-20)
    Background Diffuse intrinsic pontine glioma (DIPG) remains a clinico-radiologic diagnosis without routine tissue acquisition. Reliable imaging distinction between DIPG and other pontine tumors with potentially more favorable ...
  • Childhood adversity modulation of central autonomic network components during cognitive regulation of emotion in major depressive disorder and borderline personality disorder 
    Wainsztein, Agustina Edith; Castro, Mariana Nair; Goldberg, Ximena; Camacho Téllez, Vicente; Vulcano, Mercedes; Abulafia, Carolina; Ladrón de Guevara, Soledad; Cardoner, Narcís; Nemeroff, Charles B.; Menchón, José Manuel; Soriano-Mas, Carles; Villarreal, Mirta Fabiana; Guinjoan, Salvador Martín (Elsevier, 2021-10-10)
    Adverse childhood experiences (ACEs) have lifelong effects on emotional behavior and are frequent in Borderline Personality Disorder (BPD) and Major Depressive Disorder (MDD). The Central Autonomic Network (CAN), which ...
  • Embryoid Bodies-Based Multilineage Differentiation of Human Embryonic Stem Cells Grown on Feeder-Free Conditions 
    Isaja, Luciana; Ferriol Laffouillere, Sofía Luján; Mucci, Sofía; Rodríguez Varela, María Soledad; Romorini, Leonardo (Springer, 2021-10-06)
    Human embryonic stem cells (hESCs) can differentiate into any cell lineage (pluripotency potential) derived from the three germ layers: ectoderm, mesoderm, and endoderm. Pluripotency is usually demonstrated in vitro by ...
  • Effect of Embryo Aggregation on In Vitro Development of Adipose-Derived Mesenchymal Stem Cell-Derived Bovine Clones 
    Savy, Virginia; Alberio, Virgilia; Vans Landschoot, Geraldina; Moro, Lucía Natalia; Olea, Fernanda Daniela; Rodríguez-Álvarez, Lleretny; Salamone, Daniel Felipe (Mary Ann Liebert, 2021-10-12)
    Somatic cell nuclear transfer (SCNT) is a method with unique ability to reprogram the epigenome of a fully differentiated cell. However, its efficiency remains extremely low. In this work, we assessed and combined two ...
  • Trastornos respiratorios durante el sueño en pacientes con accidente cerebrovascular isquémico 
    Folgueira, Agustín Leandro; Valiensi, Stella Maris; de Francesco, Laura; Berrozpe, Elda Cecilia; Quiroga Narváez, Julieta; Martínez, Oscar Adolfo; Bonardo, Pablo (Universidad Nacional de Córdoba, 2021-08-24)
    Introducción: Los trastornos respiratorios durante el sueño (TRDS), sobre todo el síndrome de apneas hipopneas obstructivas (SAHOS) en pacientes con accidente cerebrovascular o ACV, son frecuentes y pueden complicar su ...
  • The Immune Response in Multiple Sclerosis 
    Rodríguez Murúa, Sofía; Farez, Mauricio Franco; Quintana, Francisco J. (Annual Reviews, 2021-10-04)
    Multiple sclerosis (MS) is a chronic autoimmune, inflammatory, and neurodegenerative disease that affects the central nervous system (CNS). MS is characterized by immune dysregulation, which results in the infiltration of ...
  • Acting centrally or peripherally: A renewed interest in the central nervous system penetration of disease-modifying drugs in multiple sclerosis 
    Correale, Jorge; Halfon, Mario Javier; Jack, Dominic; Rubstein, Adrián; Villa, Andrés (Elsevier, 2021-09-14)
    With the recent approval of cladribine tablets, siponimod and ozanimod, there has been a renewed interest into the extent to which these current generation disease-modifying therapies (DMTs) are able to cross into the ...
  • Neuromyelitis optica spectrum disorders: from pathophysiology to therapeutic strategies 
    Carnero Contentti, Edgar; Correale, Jorge (BioMed Central, 2021-09-16)
    Neuromyelitis optica (NMO) is a chronic inflammatory autoimmune disease of the central nervous system (CNS) characterized by acute optic neuritis (ON) and transverse myelitis (TM). NMO is caused by a pathogenic serum IgG ...
  • Frequency and Patterns of Brain Infarction in Patients With Embolic Stroke of Undetermined Source: NAVIGATE ESUS Trial 
    Sharma, Mukul; Smith, Eric E.; Pearce, Lesly A.; Shoamanesh, Ashkan; Perera, Kanjana S.; Coutts, Shelagh B.; Damgaard, Dorte; Ameriso, Sebastián Francisco; Rha, Joung-Ho; Modrau, Boris; Yoon, Byung-Woo; Romano, Marina; Messé, Steven R.; Barlinn, Jessica; Lambeck, Johann; Saad, Feryal; Berkowitz, Scott D.; Mundl, Hardi; Connolly, Stuart J.; NAVIGATE ESUS MIND MRI Substudy Investigators (Lippincott Williams & Wilkins, 2021-09-20)
    Background and purpose: The spectrum of brain infarction in patients with embolic stroke of undetermined source (ESUS) has not been well characterized. Our objective was to define the frequency and pattern of brain infarcts ...
  • Changes in the Care of Neurological Diseases During the First Wave of the COVID-19 Pandemic: A Single Private Center Study in Argentina 
    Calandri, Ismael Luis; Hawkes, Maximiliano Alberto; Marrodán, Mariano; Ameriso, Sebastián Francisco; Correale, Jorge; Allegri, Ricardo Francisco (Frontiers Research Foundation, 2021-09-03)
    Introduction: Healthcare systems are struggling to cope with the rapid evolution of the COVID-19 pandemic. In Argentina, the pandemic is advancing despite prolonged lockdown measures. We aim to analyze the impact of the ...

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