Repositorio Institucional FLENI: Recent submissions

  • Combination therapy of apo-transferrin and thyroid hormones enhances remyelination 
    Rosato-Siri, María Victoria; Marziali, Leandro Nazareno; Mattera, Vanesa S.; Correale, Jorge; Pasquini, Juana María (Wiley-Liss, 2020-08-20)
    The current study presents two different approaches with a view to elucidating the interaction between thyroid hormones (TH) and apo-transferrin (aTf) and their role in myelination and remyelination. First, in vitro assays ...
  • Utilidad de la identificación de anticuerpos en neuropatías periféricas, neuronopatías y ganglionopatías: revisión 
    Reisin, Ricardo C.; Salutto, Valeria L.; Aguirre, Florencia; Álvarez, Valeria; Barroso, Fabio Adrián; Bendersky, Mariana; Berardo, Andrés; Bettini, Mariela; Borrelli, Mariano M.; Chaves, Marcelo; Cisneros, Elisa M.; Conti, Eugenia; Crespo, José Manuel; di Egidio, Mariana; Figueredo, María Alejandra; Gargiulo, Gisella; Jáuregui, Agustín; Landriscina, Paula; Cejas, Luciana León; Tillard, Belén; Grupo de Trabajo de Enfermedades Neuromusculares de la Sociedad Neurológica Argentina (Sociedad Argentina de Neurología, 2020-04-04)
    Introducción En los últimos años la identificación de anticuerpos y gammapatías monoclonales ha permitido comprender la fisiopatología y favorecer el diagnóstico y tratamiento de una multiplicidad de neuropatías ...
  • Thalamic tumors in children: case series from our institution and literature review 
    Renedo, Daniela; Ferraro, Florencia; Ruiz Johnson, Agustín; Argañaraz, Romina; Giovannini, Sebastián Juan María; Pérez Zabala, Joaquín; Zemma, Elena; Mantese, Beatriz (Springer International, 2020-07-25)
    Purpose: To describe a case series of children with thalamic tumors treated at our institution in a 5-year period. Method: A retrospective and observational study was performed. The records of 15 patients between 2013 ...
  • Efecto de la pandemia COVID-19 y la cuarentena en el número de consultas, subtipos y tratamiento del accidente cerebrovascular en un centro neurológico de Argentina. 
    Rosales, Julieta Soledad; Rodriguez Pérez, María Soledad; Ameriso, Sebastián Francisco (Fundación Revista Medicina (Buenos Aires), 2020-11-05)
    La pandemia por COVID-19 y el aislamiento social preventivo y obligatorio (ASPO) han generado cambios en la organización y utilización del sistema de salud en todo el mundo. Analizamos el impacto de la situación sanitaria ...
  • Fall in the Proportion of Atherothrombotic Strokes During the Last Decade 
    Rosales, Julieta Soledad; Alet, Matías Javier; Pujol Lereis, Virginia Andrea; Ameriso, Sebastián Francisco (Saunders, 2020-12)
    Objective: To determine the proportion of subtypes of ischemic strokes, vascular risk factors and treatment prior to stroke between 1997 and 2018 in a single institution in Argentina. Methods: Demographics, risk factors, ...
  • Predictors of favorable response to implanted of ventriculoperitoneal shunt in patients with idiopathic normal pressure hydrocephalus 
    Ricciardi, Mario Emiliano; Calandri, Ismael Luis; Alessandro, Lucas; Farez, Mauricio Franco; Villalonga, Juan Francisco; Fausti, Martín; Herrmann, Frida; Allegri, Ricardo Francisco (Universidad de la Costa, 2020-12-09)
    Introduction: The indication of a ventriculoperitoneal shunt (VPS) is discussed in patients with idiopathic normal pressure hydrocephalus (iNPH), due to the heterogeneity of the response to treatment and the risks involved ...
  • Accelerometry signals’ recording protocol and database for the quantitative diagnosis of Parkinson’s disease 
    Reinaldo, Camila Belén; Bianchi, Gianfranco; Wilken, Miguel; Andrés, Daniela S. (Sociedad Argentina de Bioingeniería, 2020-12-30)
    Quantitative diagnosis of Parkinon’s disease is based on the precise measurement of specific aspects of the varied symptoms of the disease, using accelerometry signals. This work introduces a recording protocol for ...
  • Data augmentation based on dynamical systems for the classification of brain states 
    Sanz Perl, Yonatan; Pallavicini, Carla; Perez Ipiña, Ignacio; Kringelbach, Morten; Deco, Gustavo; Laufs, Helmut; Tagliazucchi, Enzo (Elsevier, 2020-07-10)
    The application of machine learning algorithms to neuroimaging data shows great promise for the classification of physiological and pathological brain states. However, classifiers trained on high dimensional data are prone ...
  • CoViD-19: perspectivas y vulnerabilidad 
    Perrone, Sergio Víctor; Bevacqua, Raúl J. (Comité de Insuficiencia Cardíaca de la Federación Argentina de Cardiología, 2020-03-24)
    La enfermedad del coronavirus 2019 (CoViD-19: Coronavirus Disease 2019) es causada por el síndrome respiratorio agudo severo coronavirus-2 (SARS-CoV-2: severe acute respiratory syndrome coronavirus 2) y se ha extendido ...
  • Statistical Model-Based Classification to Detect Patient-Specific Spike-and-Wave in EEG Signals 
    Quintero Rincón, Antonio; Muro, Valeria L.; D'Giano, Carlos; Prendes, Jorge; Batatia, Hadj (MDPI, 2020-10-29)
    Spike-and-wave discharge (SWD) pattern detection in electroencephalography (EEG) is a crucial signal processing problem in epilepsy applications. It is particularly important for overcoming time-consuming, difficult, and ...
  • Assessment of Ataxia Rating Scales and Cerebellar Functional Tests: Critique and Recommendations 
    Perez Lloret, Santiago; Van de Warrenburg, Bart; Rossi, Malco Damián; Rodríguez Blázquez, Carmen; Zesiewicz, Theresa; Saute, Jonas A M; Durr, Alexandra; Nishizawa, Masatoyo; Martínez Martín, Pablo; Stebbins, Glenn T.; Schrag, Anette; Skorvanek, Matej; MDS Rating Scales Review Committee (Wiley-Liss, 2020-10-06)
    Background: We assessed the clinimetric properties of ataxia rating scales and functional tests, and made recommendations regarding their use. Methods: A systematic literature search was conducted to identify the ...
  • Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure 
    Packer, Milton; Anker, Stefan D.; Butler, Javed; Filippatos, Gerasimos; Pocock, Stuart J.; Carson, Peter; Januzzi, James L.; Verma, Subodh; Tsutsui, Hiroyuki; Brueckmann, Martina; Jamal, Waheed; Kimura, Karen; Schnee, Janet; Zeller, Cordula; Cotton, Daniel; Bocchi, Edimar; Böhm, Michael; Choi, Dong-Ju; Perrone, Sergio Víctor; EMPEROR-Reduced Trial Investigators (Massachusetts Medical Society, 2020-10-08)
    Background: Sodium-glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of hospitalization for heart failure in patients regardless of the presence or absence of diabetes. More evidence is needed regarding the effects ...
  • GAS6 signaling tempers Th17 development in patients with multiple sclerosis and helminth infection 
    Ortiz Wilczyñski, Juan M.; Olexen, Cinthia M.; Errasti, Andrea E.; Schattner, Mirta; Rothlin, Carla V.; Correale, Jorge; Carrera Silva, Eugenio A. (Public Library of Science, 2020-11-21)
    Multiple sclerosis (MS) is a highly disabling neurodegenerative autoimmune condition in which an unbalanced immune response plays a critical role. Although the mechanisms remain poorly defined, helminth infections are known ...
  • Absence of latitudinal gradient in oligoclonal bands prevalence in Argentina 
    Negrotto, Laura; Marrodán, Mariano; Fiol, Marcela Paula; Gaitán, María Inés; Ysrraelit, María Célica; Vrech, Carlos; Pappolla, Agustín; Miguez, Jimena; Patrucco, Liliana; Cristiano, Edgardo; Rojas, Juan Ignacio; Carrá, Adriana; Chertcoff, Aníbal; Steinberg, Judith; Martinez, Alejandra D.; Curbelo, María Celeste; Cohen, Leila; Alonso, Ricardo; Garcea, Orlando; Correale, Jorge (Elsevier, 2020-11)
    Background: Like MS prevalence, oligoclonal bands (OCB) frequency seems to follow a latitudinal gradient. Argentina is extensive, latitude-wise, and previous studies have not found an MS prevalence latitudinal gradient. ...
  • Generation of myostatin edited horse embryos using CRISPR/Cas9 technology and somatic cell nuclear transfer 
    Moro, Lucía Natalia; Viale, Diego Luis; Bastón, Juan Ignacio; Arnold, Victoria; Suva, Mariana; Wiedenmann, Elisabet; Olguín, Martín; Miriuka, Santiago Gabriel; Vichera, Gabriel (Nature Publishing Group, 2020-08-24)
    The application of new technologies for gene editing in horses may allow the generation of improved sportive individuals. Here, we aimed to knock out the myostatin gene (MSTN), a negative regulator of muscle mass development, ...
  • Microcirugía de las fístulas durales arteriovenosas espinales, más un repaso de la anatomía vascular vertebromedular 
    Mormandi, Rubén; Ruella, Mauro; Villamil, Facundo; Cervio, Andrés Eduardo; Condomí Alcorta, Santiago G.; Salvat, Jorge M. (Asociación Argentina de Neurocirugía (AANC), 2020-11-17)
    Introducción: la fístula dural arteriovenosa espinal (FDAVE) es una enfermedad vascular rara, de etiología desconocida y frecuentemente subdiagnosticada. El tratamiento puede ser microquirúrgico o endovascular Material ...
  • Arritmias auriculares distintas a fibrilación auricular en pacientes con miocardiopatía hipertrófica 
    Moreno, Gerardo A.; Hernández Madrid, Antonio; Doxastakis Florida, Griselda B.; Moro Serrano, Concepción; Pedroso, Williams R.; Abello, Mauricio S. (Federación Argentina de Cardiología, 2020-09-21)
    La Fibrilación Auricular (FA), es la arritmia más frecuente en pacientes con Miocardiopatía Hipertrófica (MCH), sin embargo, existe poca información sobre otras arritmias auriculares en este grupo de pacientes. El objetivo ...
  • Biphasic cortical macro- and microstructural changes in autosomal dominant Alzheimer's disease 
    Montal, Victor; Vilaplana, Eduard; Pegueroles, Jordi; Bejanin, Alexandre; Alcolea, Daniel; Carmona-Iragui, María; Clarimón, Jordi; Levin, Johannes; Cruchaga, Carlos; Graff-Radford, Neill R.; Noble, James M.; Lee, Jae-Hong; Allegri, Ricardo Francisco; Karch, Celeste M.; Laske, Christoph; Schofield, Peter R.; Salloway, Stephen; Ances, Beau M.; Benzinger, Tammie L.S.; McDade, Eric; Bateman, Randall J.; Blesa, Rafael; Sánchez-Valle, Raquel; Lleó, Alberto; Fortea, Juan; Dominantly Inherited Alzheimer Network (John Wiley & Sons, 2020-11-16)
    Methods: In this study we tested this model fitting linear versus quadratic trajectories and computed the timing of the inflection points vertexwise of cortical thickness and cortical diffusivity-a novel marker of cortical ...
  • Intermediate phenotype of ATP13A2 mutation in two Chilean siblings: Towards a continuum between parkinsonism and hereditary spastic paraplegia 
    Miranda, Marcelo; Harmuth, Florian; Bustamante, M Leonor; Rossi, Malco Damián; Sturm, Marc; Magnusson, Ólafur Th.; Bauer, Peter; Klockgether, Thomas; Ramirez, Alfredo (Elsevier Science, 2020-12)
  • Parkin Pleiotropy: Extremely Atypical Phenotypes in Patients With Compound Heterozygous Mutations 
    Millar Vernetti, Patricio; Rossi, Malco Damián; Merello, Marcelo (Ubiquity Press, 2020-08-13)
    Background: Parkin mutations are suspected in early-onset Parkinson's disease with early motor complications, and in pedigrees showing an autosomal recessive pattern. Some compound heterozygous mutations can present with ...

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