Repositorio Institucional FLENI: Recent submissions

  • Perez Lloret, Santiago; Van de Warrenburg, Bart; Rossi, Malco Damián; Rodríguez Blázquez, Carmen; Zesiewicz, Theresa; Saute, Jonas A M; Durr, Alexandra; Nishizawa, Masatoyo; Martínez Martín, Pablo; Stebbins, Glenn T.; Schrag, Anette; Skorvanek, Matej; MDS Rating Scales Review Committee (Wiley-Liss, 2020-10-06)
    Background: We assessed the clinimetric properties of ataxia rating scales and functional tests, and made recommendations regarding their use. Methods: A systematic literature search was conducted to identify the ...
  • Packer, Milton; Anker, Stefan D.; Butler, Javed; Filippatos, Gerasimos; Pocock, Stuart J.; Carson, Peter; Januzzi, James L.; Verma, Subodh; Tsutsui, Hiroyuki; Brueckmann, Martina; Jamal, Waheed; Kimura, Karen; Schnee, Janet; Zeller, Cordula; Cotton, Daniel; Bocchi, Edimar; Böhm, Michael; Choi, Dong-Ju; Perrone, Sergio Víctor; EMPEROR-Reduced Trial Investigators (Massachusetts Medical Society, 2020-10-08)
    Background: Sodium-glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of hospitalization for heart failure in patients regardless of the presence or absence of diabetes. More evidence is needed regarding the effects ...
  • Ortiz Wilczyñski, Juan Manuel; Olexen, Cinthia M.; Errasti, Andrea E.; Schattner, Mirta; Rothlin, Carla V.; Correale, Jorge; Carrera Silva, Eugenio Antonio (Public Library of Science, 2020-11-21)
    Multiple sclerosis (MS) is a highly disabling neurodegenerative autoimmune condition in which an unbalanced immune response plays a critical role. Although the mechanisms remain poorly defined, helminth infections are known ...
  • Negrotto, Laura; Marrodán, Mariano; Fiol, Marcela Paula; Gaitán, María Inés; Ysrraelit, María Célica; Vrech, Carlos; Pappolla, Agustín; Miguez, Jimena; Patrucco, Liliana; Cristiano, Edgardo; Rojas, Juan Ignacio; Carrá, Adriana; Chertcoff, Aníbal; Steinberg, Judith; Martinez, Alejandra D.; Curbelo, María Celeste; Cohen, Leila; Alonso, Ricardo; Garcea, Orlando; Correale, Jorge (Elsevier, 2020-11)
    Background: Like MS prevalence, oligoclonal bands (OCB) frequency seems to follow a latitudinal gradient. Argentina is extensive, latitude-wise, and previous studies have not found an MS prevalence latitudinal gradient. ...
  • Moro, Lucía Natalia; Viale, Diego Luis; Bastón, Juan Ignacio; Arnold, Victoria; Suva, Mariana; Wiedenmann, Elisabet; Olguín, Martín; Miriuka, Santiago Gabriel; Vichera, Gabriel (Nature Publishing Group, 2020-08-24)
    The application of new technologies for gene editing in horses may allow the generation of improved sportive individuals. Here, we aimed to knock out the myostatin gene (MSTN), a negative regulator of muscle mass development, ...
  • Mormandi, Rubén; Ruella, Mauro; Villamil, Facundo; Cervio, Andrés Eduardo; Condomí Alcorta, Santiago G.; Salvat, Jorge M. (Asociación Argentina de Neurocirugía (AANC), 2020-11-17)
    Introducción: la fístula dural arteriovenosa espinal (FDAVE) es una enfermedad vascular rara, de etiología desconocida y frecuentemente subdiagnosticada. El tratamiento puede ser microquirúrgico o endovascular Material ...
  • Moreno, Gerardo A.; Hernández Madrid, Antonio; Doxastakis Florida, Griselda B.; Moro Serrano, Concepción; Pedroso, Williams R.; Abello, Mauricio S. (Federación Argentina de Cardiología, 2020-09-21)
    La Fibrilación Auricular (FA), es la arritmia más frecuente en pacientes con Miocardiopatía Hipertrófica (MCH), sin embargo, existe poca información sobre otras arritmias auriculares en este grupo de pacientes. El objetivo ...
  • Montal, Victor; Vilaplana, Eduard; Pegueroles, Jordi; Bejanin, Alexandre; Alcolea, Daniel; Carmona-Iragui, María; Clarimón, Jordi; Levin, Johannes; Cruchaga, Carlos; Graff-Radford, Neill R.; Noble, James M.; Lee, Jae-Hong; Allegri, Ricardo Francisco; Karch, Celeste M.; Laske, Christoph; Schofield, Peter R.; Salloway, Stephen; Ances, Beau M.; Benzinger, Tammie L.S.; McDade, Eric; Bateman, Randall J.; Blesa, Rafael; Sánchez-Valle, Raquel; Lleó, Alberto; Fortea, Juan; Dominantly Inherited Alzheimer Network (John Wiley & Sons, 2020-11-16)
    Methods: In this study we tested this model fitting linear versus quadratic trajectories and computed the timing of the inflection points vertexwise of cortical thickness and cortical diffusivity-a novel marker of cortical ...
  • Miranda, Marcelo; Harmuth, Florian; Bustamante, M Leonor; Rossi, Malco Damián; Sturm, Marc; Magnusson, Ólafur Th.; Bauer, Peter; Klockgether, Thomas; Ramirez, Alfredo (Elsevier Science, 2020-12)
  • Millar Vernetti, Patricio; Rossi, Malco Damián; Merello, Marcelo (Ubiquity Press, 2020-08-13)
    Background: Parkin mutations are suspected in early-onset Parkinson's disease with early motor complications, and in pedigrees showing an autosomal recessive pattern. Some compound heterozygous mutations can present with ...
  • Gaitán, María Inés; Marrodán, Mariano; Negrotto, Laura; Ysrraelit, María Célica; Miguez, Jimena; Alonso Serena, Marina; Pappolla, Agustín; Patrucco, Liliana; Cristiano, Edgardo; Vrech, Carlos; Rojas, Juan Ignacio; Grupo de Trabajo Relevar EM (Fundación Revista Medicina (Buenos Aires), 2020)
    El objetivo del estudio fue evaluar los aspectos clínicos y demográficos de los pacientes con esclerosis múltiple (EM) secundaria progresiva (EMSP) en los pacientes incluidos en el Registro Argentino de EM (RelevarEM, ...
  • Merello, Marcelo; Bhatia, Kailash P.; Obeso, José A. (Lancet, 2020-11-27)
  • Marrodán, Mariano; Hernández, Micaela Anahí; Kohler, Alejandro Alfredo; Correale, Jorge (Elsevier, 2020-11)
    Introduction: Establishing differential diagnosis between different inflammatory causes of acute transverse myelitis (ATM) can be difficult. The objective of this study was to see which clinical, imaging or laboratory ...
  • Marrodán, Mariano; Farez, Mauricio Franco; Balbuena Aguirre, María Eugenia; Correale, Jorge (Wiley Periodicals, 2021-02)
    Objective: To investigate the effects of leptin on different T-cell populations, in order to gain more insight into the link between leptin and obesity. Methods: Three hundred and nine RRMS patients and 322 controls ...
  • Marcó Del Pont, Francisco; Villamil, Facundo; Lorefice, Emiliano; Caffaratti, Guido; Ries Centeno, Tomás; Ruella, Mauro; Mormandi, Rubén (Masson, 2020-10-12)
  • Marcó Del Pont, Francisco; Giovannini, Sebastián Juan María; Ries Centeno, Tomás; Caffaratti, Guido; Lorefice, Emiliano; Cervio, Andrés Eduardo (Elsevier España, 2020-11-17)
    Objetivo: La laminoplastía «open door» es una técnica ampliamente utilizada para el tratamiento de la mielopatía cervical multinivel. A pesar de presentar resultados funcionales y radiológicos satisfactorios a largo plazo, ...
  • Llibre Guerra, Jorge J.; Li, Yan; Allegri, Ricardo Francisco; Chrem Méndez, Patricio Alexis; Surace, Ezequiel Ignacio; Llibre Rodríguez, Juan J.; Sosa, Ana Luisa; Aláez-Verson, Carmen; Longoria, Erika-Mariana; Tellez, Alberto; Carrillo Sánchez, Karol; Flores Lagunes, Luis Leonardo; Sánchez, Victor; Tadao Takada, Leonel; Nitrini, Ricardo; Ferreira Frota, Norberto Anizio; Benevides Lima, Joyce; Lopera, Francisco; Ramírez, Laura; Jiménez Velázquez, Ivonne (John Wiley & Sons, 2021-04)
    Introduction: A growing number of dominantly inherited Alzheimer's disease (DIAD) cases have become known in Latin American (LatAm) in recent years. However, questions regarding mutation distribution and frequency by country ...
  • Lorefice, Emiliano; Ries Centeno, Tomás; Giovannini, Sebastián Juan María; Marcó Del Pont, Francisco; Mormandi, Rubén; Cervio, Andrés Eduardo (Asociación Argentina de Neurocirugía (AANC), 2020-03-12)
    Introducción: El hemiespasmo facial primario (HFP) se produce por la hiperexcitabilidad del nervio facial y sus núcleos de origen como consecuencia de la compresión vascular. La cirugía de descompresión neurovascular se ...
  • Kivipelto, Miia; Mangialasche, Francesca; Snyder, Heather M.; Allegri, Ricardo Francisco; Andrieu, Sandrine; Arai, Hidenori; Baker, Laura; Belleville, Sylvie; Brodaty, Henry; Brucki, Sonia M.; Calandri, Ismael Luis; Caramelli, Paulo; Chen, Christopher; Chertkow, Howard; Chew, Effie; Choi, Seong H.; Chowdhary, Neerja; Crivelli, Lucía; De La Torre, Rafael; Du, Yifeng; Sevlever, Gustavo Emilio (John Wiley & Sons, 2020-07)
    Reducing the risk of dementia can halt the worldwide increase of affected people. The multifactorial and heterogeneous nature of late-onset dementia, including Alzheimer's disease (AD), indicates a potential impact of ...
  • Johnston, S Claiborne; Amarenco, Pierre; Denison, Hans; Evans, Scott R; Himmelmann, Anders; James, Stefan; Knutsson, Mikael; Ladenvall, Per; Molina, Carlos A.; Wang, Yongjun; THALES Investigators; Ameriso, Sebastián Francisco (Massachusetts Medical Society, 2020-07-16)
    Background: Trials have evaluated the use of clopidogrel and aspirin to prevent stroke after an ischemic stroke or transient ischemic attack (TIA). In a previous trial, ticagrelor was not better than aspirin in preventing ...

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