Repositorio Institucional FLENI: Envíos recientes

  • Pathogenesis of Alzheimer's disease: Involvement of the choroid plexus 
    Čarna, Maria; Onyango, Isaac G.; Katina, Stanislav; Holub, Dušan; Novotny, Jan Sebastian; Nezvedova, Marketa; Jha, Durga; Nedelska, Zuzana; Lacovich, Valentina; Vande Vyvere, Thijs; Houbrechts, Ruben; Garcia-Mansfield, Krystine; Sharma, Ritin; David-Dirgo, Victoria; Vyhnalek, Martin; Texlova, Kateřina; Chaves, Hernán; Bakkar, Nadine; Pertierra, Lucía; Sevlever, Gustavo Emilio (Wiley, 2023-02-24)
    The choroid plexus (ChP) produces and is bathed in the cerebrospinal fluid (CSF), which in aging and Alzheimer's disease (AD) shows extensive proteomic alterations including evidence of inflammation. Considering inflammation ...
  • Abstract WP14: A Patient-level Data Euclidean-matched Analysis Of Reperfusion Therapies In Acute Ischemic Stroke From The Latin American Stroke Registry (lase) 
    Barboza, Miguel A.; Torrealba-Acosta, Gabriel; Valdez, Hector; Arauz-Gongora, Antonio; Abanto Argomedo, Carlos; Amaya, Pablo; Ameriso, Sebastián Francisco; Bonardo, Pablo; Cano, Vanessa; Diaz-Escobar, Luis; Ecos, Rosa Lizbeth; Fernández Morales, Huberth; Gómez Schneider, Maia Macarena; Gongora Rivera, Fernando F.; Huamani, Charles; Lavados, Pablo M.; Marquez Romero, Juan Manuel; Martins, Sheila C.; Navia, Víctor Hugo; Pujol Lereis, Virginia Andrea (Lippincott Williams & Wilkins, 2023-02-02)
    Introduction: As acute stroke therapies expand to less well-resourced regions, it is imperative to study real-world data to assess outcomes and the quality of stroke care. The present study analyzes clinical, and imaging ...
  • Cross-sectional and longitudinal comparisons of biomarkers and cognition among asymptomatic middle-aged individuals with a parental history of either autosomal dominant or late-onset Alzheimer's disease 
    Xiong, Chengjie; McCue, Lena M.; Buckles, Virginia; Grant, Elizabeth; Agboola, Folasade; Coble, Dean; Bateman, Randall J.; Fagan, Anne M.; Benzinger, Tammie L.S.; Hassenstab, Jason; Schindler, Suzanne E.; McDade, Eric; Moulder, Krista L.; Gordon, Brian A.; Cruchaga, Carlos; Day, Gregory S.; Ikeuchi, Takeshi; Suzuki, Kazushi; Allegri, Ricardo Francisco; Dominantly Inherited Alzheimer Network (Wiley, 2023-01-14)
    Background: Comparisons of late-onset Alzheimer's disease (LOAD) and autosomal dominant AD (ADAD) are confounded by age. Methods: We compared biomarkers from cerebrospinal fluid (CSF), magnetic resonance imaging, and ...
  • Embracing Monogenic Parkinson's Disease: The MJFF Global Genetic PD Cohort 
    Vollstedt, Eva-Juliane; Schaake, Susen; Lohmann, Katja; Padmanabhan, Shalini; Brice, Alexis; Lesage, Suzanne; Tesson, Christelle; Vidailhet, Marie; Wurster, Isabel; Hentati, Faycel; Mirelman, Anat; Giladi, Nir; Marder, Karen S.; Waters, Cheryl; Fahn, Stanley; Kasten, Meike; Brüggemann, Norbert; Rossi, Malco Damián; Merello, Marcelo; MJFF Global Genetic Parkinson's Disease Study Group (Wiley, 2023-01-24)
    Background: As gene-targeted therapies are increasingly being developed for Parkinson's disease (PD), identifying and characterizing carriers of specific genetic pathogenic variants is imperative. Only a small fraction of ...
  • Emerging concepts in heart failure management and treatment: circulatory support with extracorporeal membrane oxygenation (ECMO) 
    Swedzky, Federico; Barbagelata, Alejandro; Perrone, Sergio Víctor; Kaplinsky, Edgardo; Ducharme, Anique (Bioexcel Publishing Ltd., 2023-01-04)
    Circulatory support with extracorporeal membrane oxygenation (ECMO) is being increasingly used in several critical situations but evidence of its impact on outcomes is inconsistent. Understanding of the specific indications ...
  • Apoplejía pituitaria e infección por SARS-CoV-2 (COVID-19) 
    Ruella, Mauro; Caffaratti, Guido; Katz, Débora Adela; Marengo, Ricardo; Cervio, Andrés Eduardo (Fundación Revista Medicina, 2023-01)
    La infección por coronavirus (SARS-CoV-2/COVID-19) es responsable de un diverso rango de manifestaciones extrapulmonares entre las cuales se destaca el compromiso neurológico directo o indirecto. La apoplejía hipofisaria ...
  • Emerging concepts in heart failure management and treatment: focus on point-of-care ultrasound in cardiogenic shock 
    Ruben, Mariela; Molinas, María Sol; Paladini, Hugo; Khalife, Wissam; Barbagelata, Alejandro; Perrone, Sergio Víctor; Kaplinsky, Edgardo (Bioexcel Publishing Ltd, 2023-01-04)
    Point-of-care ultrasound (POCUS) plays a strategic role in the diagnostic and therapeutic evaluation of critically ill patients and, especially, in those who are haemodynamically unstable. In this context, POCUS allows a ...
  • Glial Cell Metabolic Profile Upon Iron Deficiency: Oligodendroglial and Astroglial Casualties of Bioenergetic Adjustments 
    Rosato-Siri, María Victoria; Martino Adami, Pamela V.; Guitart, María Eugenia; Verstraeten, Sandra V.; Morelli, Laura; Correale, Jorge; Pasquini, Juana María (Humana Press, 2023-01-03)
    Iron deficiency (ID) represents one of the most prevalent nutritional deficits, affecting almost two billion people worldwide. Gestational iron deprivation induces hypomyelination due to oligodendroglial maturation ...
  • Clinical Applicability of the Sellar Barrier Concept in Patients with Pituitary Apoplexy: Is It Possible? 
    Pailler, José Ignacio; Villalonga, Juan Francisco; Ries Centeno, Tomás; Saenz, Amparo; Baldoncini, Matías; Pipolo, Derek Orlando; Cárdenas Ruiz-Valdepeñas, Eugenio; Kaen, Ariel; Hirtler, Lena; Roytowski, David; Solari, Domenico; Cervio, Andrés Eduardo; Campero, Álvaro (MDPI AG, 2023-01-05)
    There is evidence of association between sellar barrier thickness and intraoperative cerebrospinal fluid (CSF) leakage, impacting the postoperative prognosis of the patients. The aim of this study is to analyze the clinical ...
  • LatAm Fingers Initiative: Bringing Diversity Upfront 
    Crivelli, Lucía (The Alzheimer's Association, 2022-12)
  • Life events and the onset of motor symptoms in Parkinson's disease 
    Páez Maggio, Mauricio; Rossi, Malco Damián; Martinez, V.; Wainberg, Florencia N.; Merello, Marcelo (Elsevier, 2023-01-11)
    Background: Whether there may be any relationship between stressful or traumatic life events (LE) and the subsequent motor symptoms onset in Parkinson's disease (PD) is still controversial. Objectives: To explore whether ...
  • Multimodal brain age estimates relate to Alzheimer disease biomarkers and cognition in early stages: a cross-sectional observational study 
    Millar, Peter R.; Gordon, Brian A.; Luckett, Patrick H.; Benzinger, Tammie L.S.; Cruchaga, Carlos; Fagan, Anne M.; Hassenstab, Jason; Perrin, Richard J.; Schindler, Suzanne E.; Allegri, Ricardo Francisco; Day, Gregory S.; Farlow, Martin R.; Mori, Hiroshi; Nübling, Georg; Dominantly Inherited Alzheimer Network; Bateman, Randall J.; Morris, John C.; Ances, Beau M. (eLife Sciences Publications, 2023-01-06)
    Background: Estimates of 'brain-predicted age' quantify apparent brain age compared to normative trajectories of neuroimaging features. The brain age gap (BAG) between predicted and chronological age is elevated in symptomatic ...
  • Emerging concepts in heart failure management and treatment: focus on current guideline-directed medical therapy for heart failure with reduced ejection fraction 
    Ospina González, Oscar Eduardo; Llanos Mejía, Diana Catalina; Kaplinsky, Edgardo; Barbagelata, Alejandro; Perrone, Sergio Víctor (Bioexcel Publishing, 2023-01-04)
    ne of the most relevant and differentiating aspects provided by the 2021 European Society of Cardiology guidelines for the diagnosis and treatment of acute and chronic heart failure is the retraction of the historical ...
  • LatAm Fingers Initiative: Challenges and opportunities of launching amulticultural trial in pandemic times 
    Calandri, Ismael Luis; Crivelli, Lucía; Caramelli, Paulo; Lopera, Francisco; Nitrini, Ricardo; Sosa, Ana Luisa; Salinas Contreras, Rosa María; Suemoto, Claudia Kimie; Velilla, Lina M.; Sanches Yassuda, Mónica; Sevlever, Gustavo Emilio; Allegri, Ricardo Francisco; LatAm FINGERS (The Alzheimer's Association, 2022-12-20)
  • LatAm FINGERS:Overcoming Barriers for a Dementia Prevention Trial Startup 
    Calandri, Ismael Luis; Crivelli, Lucía; Caramelli, Paulo; Lopera, Francisco; Nitrini, Ricardo; Sosa, Ana Luisa; Salinas Contreras, Rosa María; Suemoto, Claudia Kimie; Velilla, Lina M.; Sanches Yassuda, Mónica; Sevlever, Gustavo Emilio; Allegri, Ricardo Francisco; LatAm FINGERS (The Alzheimer's Association, 2022)
  • Comparison of amyloid accumulation between Down syndrome and autosomal-dominant Alzheimer disease 
    Boerwinkle, Anna H.; Gordon, Brian A.; Wisch, Julie K.; Flores, Shaney; Henson, Rachel L.; Butt, Omar H.; Chen, Charles D.; Benzinger, Tammie L.S.; Fagan, Anne M.; Handen, Benjamin L.; Christian, Bradley T.; Head, Elizabeth; Mapstone, Mark; Klunk, William E.; Rafii, Michael S.; O’Bryant, Sid E.; Price, Julie C.; Schupf, Nicole; Allegri, Ricardo Francisco; Alzheimer's Biomarker Consortium-Down Syndrome; Dominantly Inherited Alzheimer Network (The Alzheimer’s Association, 2022)
  • Shared decision making in the treatment of multiple sclerosis: A consensus based on Delphi methodology 
    Alonso, Ricardo; Carnero Contentti, Edgar; Graña, Marcos; Linares, Ramiro; López, Pablo Adrián; Mainella, Carolina; Marrodán, Mariano; Miguez, Jimena; Pagani Cassará, Fátima; Tavolini, Darío; Batagelj, Sebastián (Elsevier, 2022-12-09)
    Shared decision making is a way of incorporating patients' preferences and values into the decisions regarding the treatment and follow-up plan for the condition that affects them. It is currently applied mainly in the ...
  • Influenza and pneumococcal vaccine prescription for adults during COVID-19 first wave in three regions of Argentina 
    Matta, María Gabriela; Pulido, Laura; Herrera Paz, Juan José; Picco, José Miguel; Wolff, Sebastian; Tse, Gary; Garcia-Zamora, Sebastián (Elsevier, 2023-02-24)
    Immunizations for influenza and pneumococcus are effective interventions in reducing morbidity and mortality. The objective of this study was to describe the vaccination rates in volunteers from three regions of Argentina ...
  • Teleneuropsychological assessment in South America: A perspective from patients and neuropsychologists 
    Arruabarrena, Micaela María; Martin, María Eugenia; Calandri, Ismael Luis; Corvalán, Nicolás; Helou, María Belén; Martínez Canyazo, Carlos; Crivelli, Lucía (Universidad de la Costa, 2022-12-23)
    Teleneuropsychology (teleNP) in Argentina was promoted by the COVID-19 pandemic. This investigation aimed to evaluate patients’ and neuropsychologists’ satisfaction with teleNP and to identify the advantages and disadvantages ...
  • Emerging concepts in heart failure management and treatment: focus on vericiguat 
    Kaplinsky, Edgardo; Perrone, Sergio Víctor; Barbagelata, Alejandro (Bioexcel Publishing, 2023-01-04)
    The nitric oxide (NO)-soluble guanylate cyclase (sGC)-cyclic guanosine monophosphate (cGMP) pathway is dysregulated in patients with heart failure (HF) resulting in myocardial and vascular dysfunction that contributes to ...