Neurología: Recent submissions

  • Change in Cerebrospinal Fluid Tau Microtubule Binding Region Detects Symptom Onset, Cognitive Decline, Tangles, and Atrophy in Dominantly Inherited Alzheimer's Disease 
    Horie, Kanta; Li, Yan; Barthélemy, Nicolas R.; Gordon, Brian A.; Hassenstab, Jason; Benzinger, Tammie L.S.; Fagan, Anne M.; Morris, John C.; Karch, Celeste M.; Xiong, Chengjie; Allegri, Ricardo Francisco; Chrem Méndez, Patricio Alexis; Ikeuchi, Takeshi; Kasuga, Kensaku; Noble, James M.; Farlow, Martin R.; Chhatwal, Jasmeer P.; Day, Gregory S.; Schofield, Peter R.; Dominantly Inherited Alzheimer Network (Wiley, 2023-03-16)
    Objective: Identifying cerebrospinal fluid measures of the microtubule binding region of tau (MTBR-tau) species that reflect tau aggregation could provide fluid biomarkers that track Alzheimer's disease related neurofibrillary ...
  • Incidence of COVID-19 after vaccination in people with multiple sclerosis in Argentina: Data from the nationwide registry RelevarEM 
    Rojas, Juan Ignacio; Luetic, Geraldine G.; Vrech, Carlos; Pappolla, Agustín; Patrucco, Liliana; Cristiano, Edgardo; Marrodán, Mariano; Ysrraelit, María Célica; Fiol, Marcela Paula; Correale, Jorge; Cohen, Leila; Alonso, Ricardo; Silva, Berenice Anabel; Casas, Magdalena; Garcea, Orlando; Deri, Norma; Burgos, Marcos; Liwacki, Susana; Tkachuk, Verónica A.; Barboza, Andrés G. (Elsevier B. V., 2022-12)
    The objective of the study was to evaluate the incidence of COVID-19 after complete vaccination in people with multiple sclerosis (PwMS) included in the Argentinean MS and NMOSD registry (RelevarEM, NCT03375177). Methods: ...
  • Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study 
    Boerwinkle, Anna H.; Gordon, Brian A.; Wisch, Julie K.; Flores, Shaney; Henson, Rachel L.; Butt, Omar H.; McKay, Nicole S.; Chen, Charles D.; Benzinger, Tammie L.S.; Fagan, Anne M.; Handen, Benjamin L.; Christian, Bradley T.; Head, Elizabeth; Mapstone, Mark; Rafii, Michael S.; Alzheimer's Biomarker Consortium-Down Syndrome; Dominantly Inherited Alzheimer Network; Allegri, Ricardo Francisco; Chrem Méndez, Patricio Alexis; Egido, Noelia (Elsevier, 2022-12-12)
    Background: Important insights into the early pathogenesis of Alzheimer's disease can be provided by studies of autosomal dominant Alzheimer's disease and Down syndrome. However, it is unclear whether the timing and spatial ...
  • Control of Vascular Risk Factors and Response to Stroke Symptoms in Argentina During the COVID-19 Quarantine. The SIFHON-COVID Population Survey 
    Rodríguez Pérez, María Soledad; Rosales, Julieta Soledad; Dossi, Daiana Elizabeth; Ameriso, Sebastián Francisco (Frontiers Research Foundation, 2022-04-11)
    Background and objectives: In preparation for the suspected influx of COVID-19 patients, many healthcare systems reduced or discontinued provision of "non-urgent" care. This decision had potential impact on stroke prevention ...
  • Autosomal dominant and sporadic late onset Alzheimer's disease share a common in vivo pathophysiology 
    Morris, John C.; Weiner, Michael W.; Xiong, Chengjie; Beckett, Laurel A.; Coble, Dean; Saito, Naomi; Aisen, Paul S.; Allegri, Ricardo Francisco; Benzinger, Tammie L.S.; Berman, Sarah B.; Cairns, Nigel; Carrillo, María C.; Chui, Helena C.; Chhatwal, Jasmeer P.; Cruchaga, Carlos; Fagan, Anne M.; Farlow, Martin R.; Fox, Nick C.; Ghetti, Bernardino; Goate, Alison M. (Oxford University Press, 2022-10-21)
    The extent to which the pathophysiology of autosomal dominant Alzheimer's disease corresponds to the pathophysiology of 'sporadic' late onset Alzheimer's disease is unknown, thus limiting the extrapolation of study findings ...
  • Nicotinamide Adenine Dinucleotide Supplementation in Parkinson's Disease: A Potential Disease-Modifying Agent Targeting Multiple Pathways 
    Martínez Villota, Viviana Alexandra; Rossi, Malco Damián; Castillo Torres, Sergio Andrés (Wiley, 2022-06-25)
  • Nomenclature of Genetic Movement Disorders: Recommendations of the International Parkinson and Movement Disorder Society Task Force - An Update 
    Lange, Lara M.; Gonzalez-Latapi, Paulina; Rajalingam, Rajasumi; Tijssen, Marina A.J.; Ebrahimi-Fakhari, Darius; Gabbert, Carolin; Ganos, Christos; Ghosh, Rhia; Kumar, Kishore R.; Lang, Anthony E.; Rossi, Malco Damián; Van der Veen, Sterre; Van de Warrenburg, Bart; Warner, Tom; Lohmann, Katja; Klein, Christine; Marras, Connie; Task Force on Genetic Nomenclature in Movement Disorders (Wiley-Liss, 2022-05)
    In 2016, the Movement Disorder Society Task Force for the Nomenclature of Genetic Movement Disorders presented a new system for naming genetically determined movement disorders and provided a criterion-based list of confirmed ...
  • Neurocognitive Assessment in Addictions 
    Waisman Campos, Marcela; Cerviño, Cecilia Verónica; Bagnati, Pablo M.; Navarro, Rodrigo Eduardo; Barrios Coronel, Iván; González-Urbieta, Israel; García Franco, Oscar; O’Higgins, Marcelo Gerardo; Castaldelli-Maia, João Mauricio; Ventriglio, Antonio; Almirón-Santacruz, José; Torales, Julio César (EFACIM. Editorial de la Facultad de Ciencias Médicas de la Universidad Nacional de Asunción, 2022-04)
    Introduction: This paper aims to provide a brief review of recent evidence considering addictionrelated cognitive factors. Clinical observations, conventional wisdom, and well-reasoned theoretical mechanisms suggest that ...
  • Addressing the disparities in dementia risk, early detection and care in Latino populations: Highlights from the second Latinos & Alzheimer's Symposium 
    Quiroz, Yakeel T.; Solis, Michele; Aranda, María P.; Arbaje, Alicia I.; Arroyo-Miranda, Mirna; Cabrera, Laura Y.; Carrasquillo, Minerva Maria; Corrada, Maria M.; Crivelli, Lucía; Diminich, Erica D.; Dorsman, Karen A.; Gonzales, Mitzi; González, Héctor M.; Gonzalez-Seda, Ana L.; Grinberg, Lea T.; Guerrero, Lourdes R.; Hill, Carl V.; Jiménez Velázquez, Ivonne; Llibre Guerra, Jorge J.; Lopera, Francisco (John Wiley & Sons, 2022-09)
    The Alzheimer's Association hosted the second Latinos & Alzheimer's Symposium in May 2021. Due to the COVID-19 pandemic, the meeting was held online over 2 days, with virtual presentations, discussions, mentoring sessions, ...
  • Evaluating Rates of Recurrent Ischemic Stroke Among Young Adults With Embolic Stroke of Undetermined Source: The Young ESUS Longitudinal Cohort Study 
    Perera, Kanjana S.; De Sa Boasquevisque, Danielle; Rao-Melacini, Purnima; Taylor, Amanda; Cheng, Anna; Hankey, Graeme J.; Lee, Sarah; Marti Fabregas, Joan; Ameriso, Sebastián Francisco; Field, Thalia S.; Arauz-Gongora, Antonio; Coutts, Shelagh B.; Arnold, Marcel; Mikulik, Robert; Toni, Danilo; Mandzia, Jennifer; Veltkamp, Roland C.; Meseguer, Elena; Haeusler, Karl Georg; Young ESUS Investigators (American Medical Association, 2022-05-01)
    Importance: Cryptogenic strokes constitute approximately 40% of ischemic strokes in young adults, and most meet criteria for the embolic stroke of undetermined source (ESUS). Two randomized clinical trials, NAVIGATE ESUS ...
  • First presentation with neuropsychiatric symptoms in autosomal dominant Alzheimer's disease: the Dominantly Inherited Alzheimer's Network Study 
    O'Connor, Antoinette; Rice, Helen; Barnes, Josephine; Ryan, Natalie S.; Liu, Kathy Y.; Allegri, Ricardo Francisco; Berman, Sarah B.; Ringman, John M.; Cruchaga, Carlos; Farlow, Martin R.; Hassenstab, Jason; Lee, Jae-Hong; Perrin, Richard J.; Xiong, Chengjie; Gordon, Brian A.; Levey, Allan I.; Goate, Alison M.; Graff-Radford, Neill R.; Levin, Johannes; Dominantly Inherited Alzheimer Network (BMJ Publishing Group, 2022-12-15)
  • Genetic Diagnosis in Movement Disorders. Use of Whole-Exome Sequencing in Clinical Practice 
    Millar Vernetti, Patricio; Ruiz Yanzi, María Agustina; Rossi, Malco Damián; Merello, Marcelo (Ubiquity Press, 2022-04)
  • Susac syndrome: challenges in the diagnosis and treatment 
    Marrodán, Mariano; Fiol, Marcela Paula; Correale, Jorge (Oxford University Press, 2022-04-29)
    Susac syndrome is a disorder thought to be mediated by an autoimmune response towards endothelial cells, leading to a characteristic clinical triad of encephalopathy, visual disturbances due to branch arterial occlusions ...
  • Conocimiento sobre demencia en la población general, familiares, estudiantes y trabajadores de la salud en la Ciudad Autónoma de Buenos Aires 
    Gallo, María Fernanda; Tabernero, María Eugenia; Berrios, Waleska; Cores, Evangelina Valeria; Deschle, Florencia (Sociedad Neurológica Argentina, 2022-04)
    Resumen Conocer la presencia de ideas erróneas con relación a las demencias en distintas poblaciones permite llevar a cabo intervenciones tendientes a mejorar el acceso al conocimiento. Objetivo Evaluar el conocimiento ...
  • The central vein sign is present in most infratentorial multiple sclerosis plaques 
    Gaitán, María Inés; Paday Formenti, María Emilia; Calandri, Ismael Luis; Ysrraelit, María Célica; Yañez, Paulina; Correale, Jorge (Elsevier, 2022-02)
    Background and purpose: There is growing evidence supporting the presence of the central vein sign (CVS) in the supratentorial brain as an imaging biomarker for multiple sclerosis (MS) diagnosis. Recently, using optimized ...
  • Iron metabolism in oligodendrocytes and astrocytes: friend or foe? 
    Pasquini, Juana María; Rosato-Siri, María Victoria; Martino Adami, Pamela V.; Guitart, María Eugenia; Marcora, María Silvina; Morelli, Laura; Correale, Jorge (Reunión de Sociedades de Biociencias, 2021-11)
    Recent reports show that astrocytes (AST) are able to create a permissive environment for remyelination through their action on oligodendrocyte (OLG) precursor migration, proliferation, and differentiation. When ...
  • Improvement of episodic memory retention by a memory reactivation intervention across the lifespan: from younger adults to amnesic patients 
    Fernández, Rodrigo Sebastián; Picco, Soledad; Beron, Juan Cruz; Bavassi, Luz; Campos, Jorge; Allegri, Ricardo Francisco; Pedreira, María Eugenia (Nature Pub. Group, 2022-04-05)
    Spontaneous reactivation of recently acquired memories is a fundamental mechanism of memory stabilization. Re-exposure to specific learned cues during sleep or awake states, namely targeted memory reactivation, has been ...
  • Characteristics of children ≤36 months of age with DIPG: A report from the international DIPG registry 
    Bartlett, Allison L.; Lane, Adam; Chaney, Brooklyn; Yanez Escorza, Nancy; Black, Katie; Cochrane, Anne; Minturn, Jane; Bartels, Ute; Warren, Kathy; Hansford, Jordan; Ziegler, David; Diez, Blanca; Goldman, Stewart; Packer, Roger; Kieran, Mark; DeWire-Schottmiller, Mariko; Erker, Craig; Monje-Deisseroth, Michelle; Wagner, Lars; Koschmann, Carl (Oxford University Press, 2022-12-01)
    Background: Children ≤36 months with diffuse intrinsic pontine glioma (DIPG) have increased long-term survival (LTS, overall survival (OS) ≥24 months). Understanding distinguishing characteristics in this population is ...
  • Oculomotor Abnormalities during Reading in the Offspring of Late-Onset Alzheimer's Disease 
    Fernández, Gerardo; González, Ana Paula; Abulafia, Carolina; Fiorentini, Leticia; Agamennoni, Osvaldo; Guinjoan, Salvador Martín (Bentham Science Publishers, 2022)
    Introduction: Eye movement patterns during reading are well defined and documented. Each eye movement ends up in a fixation point, which allows the brain to process the incoming information and program the following saccade. ...
  • Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid 
    Drieu, Antoine; Du, Siling; Storck, Steffen E.; Rustenhoven, Justin; Papadopoulos, Zachary; Dykstra, Taitea; Zhong, Fenghe; Kim, Kyungdeok; Blackburn, Susan; Mamuladze, Tornike; Harari, Oscar; Karch, Celeste M.; Bateman, Randall J.; Perrin, Richard J.; Farlow, Martin R.; Chhatwal, Jasmeer P.; Dominantly Inherited Alzheimer Network; Hu, Song; Randolph, Gwendalyn J.; Allegri, Ricardo Francisco (Nature Publishing Group, 2022-11)
    Macrophages are important players in the maintenance of tissue homeostasis1. Perivascular and leptomeningeal macrophages reside near the central nervous system (CNS) parenchyma2, and their role in CNS physiology has not ...

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