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Chapter 3 - Effect of infections on multiple sclerosis

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dc.contributor.author Correale, Jorge
dc.contributor.author Marrodán, Mariano
dc.date.accessioned 2024-10-22T16:36:29Z
dc.date.available 2024-10-22T16:36:29Z
dc.date.issued 2024
dc.identifier.citation Correale J, Marrodan M. Chapter 3 - Effect of infections on multiple sclerosis. En: Quintana FJ, editor. Mechanisms of Disease Pathogenesis in Multiple Sclerosis Academic Press; 2024: 87-124. doi.org/10.1016/C2020-0-00411-1. es_ES
dc.identifier.uri https://doi.org/10.1016/B978-0-12-823848-6.00003-8
dc.identifier.uri https://repositorio.fleni.org.ar/xmlui/handle/123456789/1221
dc.description.abstract Evidence from both epidemiological and experimental studies, implicate infections present during childhood and young adulthood to the development and/or exacerbation of MS. Possible infectious agents include Epstein–Barr virus, human Herpesvirus-6, human endogenous retrovirus families, and coronavirus. In addition, common upper respiratory tract, gastrointestinal and urogenital tract bacterial infections have also been associated with MS exacerbations. In contrast, helminth infections appear to attenuate the course of MS, with effects extending beyond simple response to an infectious agent. Although the cause of MS in humans remains inconclusive, an infectious etiology is one possibility, as microbial agents may modulate the immune system in genetically susceptible individuals. Decoding the complex interaction between central nervous system cells, infections caused by various pathogens, and the immune response to those infections may improve our understanding of pathogenic mechanisms present in MS, and help develop new treatment strategies and/or prevent relapses. es_ES
dc.language.iso eng es_ES
dc.publisher Elsevier es_ES
dc.subject Multiple Sclerosis es_ES
dc.subject Esclerosis Múltiple es_ES
dc.subject Infecciones es_ES
dc.subject Infections es_ES
dc.title Chapter 3 - Effect of infections on multiple sclerosis es_ES
dc.type info:eu-repo/semantics/bookPart es_ES
dc.description.fil Fil: Correale, Jorge. Fleni. Departamento de Neurología. Servicio de Neuroinmunología y Enfermedades Desmielinizantes; Argentina
dc.description.fil Fil: Marrodán, Mariano. Fleni. Departamento de Neurología. Servicio de Neuroinmunología y Enfermedades Desmielinizantes; Argentina
dc.relation.ispartofPAGINATION 87-124
dc.relation.ispartofTITLE Mechanisms of Disease Pathogenesis in Multiple Sclerosis
dc.type.snrd info:ar-repo/semantics/parte de libro es_ES


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