Neurología Cognitiva: Envíos recientes

  • A harmonized framework for studying exceptional cognitive aging in Latin America 
    Crivelli, Lucía; Fernández, Rodrigo Sebastián; Corvalán, Nicolás; Sosa, Ana Luisa; Acosta, Daisy; Agnoletti, Giulia; Surace, Ezequiel Ignacio; Acosta, Issac; Caramelli, Paulo; Aguillón, David; Leniz Martelli, Javiera; Duque Peñailillo, Lissette; Custodio, Nilton; Charamelo Baieti, Ana; Damian, Andrés; Llibre Rodríguez, Juan J.; Allegri, Ricardo Francisco; Prina, Mathew; Rogalski, Emily; Ibañez, Laura (John Wiley & Sons, 2026-04-14)
    Introduction: Biological, genetic, and sociocultural factors underlying cognitive resilience and resistance to pathology remain unexplored in Latin America. The Life-Course Epidemiology of Aging, Resilience, and Neurodegeneration ...
  • Primer Consenso Argentino en Esquizofrenia : tercera parte. Lineamientos para el abordaje integral del tratamiento 
    Corrales, Alejo; Abadi, Andrea; Bartoli, Gastón; Benavente Pinto, Carlos; Cabrera, Adrián; Camino, Sebastián; Corral, Ricardo; Delmonte, Guillermo; García Bonetto, Gerardo; Garay, Cristian Javier; Gargoloff, Damián; Gargoloff, Pedro; Goldchuk, Aníbal; Iveli, María Florencia; Jufe, Gabriela; Lamaison, Fabián; Leiderman, Eduardo; López Mato, Andrea; Marengo, Eliana; Waisman Campos, Marcela (Polemos, 2026-04-10)
    Este documento corresponde a la tercera parte del Primer Consenso Argentino sobre el manejo de la esquizofrenia y tiene como objetivo sintetizar la evidencia científica actualizada sobre los abordajes terapéuticos en ...
  • Primer Consenso Argentino para el Manejo de la Esquizofrenia : Segunda Parte. Consideraciones clínicas y diagnósticas 
    Corrales, Alejo; Abadi, Andrea; Bartoli, Gastón; Benavente Pinto, Carlos; Cabrera, Adrián; Camino, Sebastián; Corral, Ricardo; Delmonte, Guillermo; García Bonetto, Gerardo; Garay, Cristian Javier; Gargoloff, Damián; Gargoloff, Pedro; Goldchuk, Aníbal; Iveli, María Florencia; Jufe, Gabriela; Lamaison, Fabián; Leiderman, Eduardo; López Mato, Andrea; Marengo, Eliana; Waisman Campos, Marcela (Polemos, 2026-01-10)
    Este documento constituye la segunda parte del Primer Consenso Argentino sobre el Manejo de la Esquizofrenia y presenta una síntesis actualizada de la evidencia disponible sobre los aspectos clínicos y diagnósticos del ...
  • Longitudinal subcortical volume changes and their correlations with multiple PET and fluid biomarkers in dominantly inherited Alzheimer's disease 
    Choo, Il Han; Park, Hoyoung; Gordon, Brian A.; Bateman, Randall J.; Dominantly Inherited Alzheimer Network; Daniels, Alisha; Courtney, Laura; Ziegemeier, Angela; Skrbec, Karina; Hellm, Cortaiga; Martin, Mariana; Ziegemeier, Ellen; Bartzel, Jamie; McDade, Eric; Libre-Guerra, Jorge J.; Supnet Bell, Charlene; Xiong, Chengie; Chrem Méndez, Patricio Alexis; Surace, Ezequiel Ignacio; Vázquez, Silvia; Allegri, Ricardo Francisco (Elsevier, 2026-04)
    Background: Alzheimer's disease postmortem studies demonstrate that amyloid plaques and neurofibrillary tangles are present in subcortical regions. Objective: To investigate longitudinal subcortical structural changes in ...
  • Brief Cognitive Screening Tools for Dementia in Low-Educated Population from South America : A Systematic Review 
    Chambergo Michilot, Diego; Custodio, Nilton; Montesinos, Rosa; Custodio, Belen; Cahuapaza Gutierrez, Nelson Luis; Caramelli, Paulo; Calandri, Ismael Luis; Dozzi Brucki, Sonia María; Suemoto, Claudia Kimie; Allegri, Ricardo Francisco; Slachevsky, Andrea; Parodi, Jose F. (Karger, 2025-09-29)
    Introduction: Despite less education being common in Latin America, there is no systematic review on the use of brief cognitive screening (BCS) tools in illiterate and low-educated adults in the region. We systematically ...
  • Consenso Argentino para el diagnóstico de las demencias. Primera parte : introducción, metodología de trabajo, escenario actual y algoritmos diagnósticos 
    Bagnati, Pablo M.; Allegri, Ricardo Francisco; Demey, Ignacio; Bártoli, Gastón; Bérgamo, Yanina; Campos, Jorge; Castro, Diego M.; Chrem Méndez, Patricio Alexis; Cristalli, Diana Olga; Fernández, María Cecilia; Fernández, María Laura; García Lombardi, Juan Pablo; Kremer, Janus; Magrath Guimet, Nahuel; Ollari, Juan; Osa Sanz, Emilia; Russo, María Julieta; Surace, Ezequiel Ignacio; Vázquez, Silvia; Waisman Campos, Marcela (Vertex, 2026-01-10)
    El Consenso Argentino para el diagnóstico de las demencias es una iniciativa de la Asociación Argentina de Psiquiatría Biológica (AAPB). Este documento tuvo como objetivo principal elaborar un instrumento eficiente para ...
  • International consensus for the assessment of social cognition in neurocognitive disorders: framework definition and clinical recommendations of the SIGNATURE initiative 
    Alessandra, Dodich; Andrea, Panzavolta; Giulia, Funghi; Claudia, Meli; Cristina, Festari; Thanos, Chatzikostopoulos; Christian, Chicherio; Clarens, María Florencia; Fabricio, Ferreira de Oliveira; Marco, Filardi; Agustin, Ibanez; Laura, Invernizzi; Thibaud, Lebouvier; Giancarlo, Logroscino; Sarah E., MacPherson; Riccardo, Manca; Camillo, Marra; Jordi A., Matias-Guiu; SIGNATURE Consortium (BioMed Central Ltd., 2025-12-06)
    Background: Socio-cognitive assessment in neurocognitive disorders (NCDs) is rare in clinical practice and no consensus exists as to a uniform operationalization of socio-cognitive measures for NCDs in memory clinics. The ...
  • Gait Speed is Associated with Executive Function in Latin American Older Adults from LatAmFINGERS 
    Gutiérrez, Myriam; Marroig, Alejandra; Delgado, Carolina; Slachevsky, Andrea; Charamelo, Ana; Aguillon Niño, David Fernando; Crivelli, Lucía (Oxford, 2025-12)
    Dementia prevalence is increasing with aging worldwide, a leading cause of disability in Latin American Countries (LAC). Interestingly, physical performance has been reported as a predictor of cognitive decline, and gait ...
  • Functional validation of the PSEN1 R358P and PSEN1 T119I variants in Alzheimer's Disease: an in vitro study 
    García Chialva, Diego; Cifarelli, Diego; Isaja, Luciana; Apecetche, Manuela; Martínes Ojeda, Laura; Itzcovich, Tatiana; Chrem Méndez, Patricio Alexis; Sevlever, Gustavo Emilio; Scassa, Maria; Surace, Ezequiel Ignacio; Romorini, Leonardo (Wiley, 2025-12-23)
    Background Alzheimer's disease (AD) is a neurodegenerative disorder and the leading cause of dementia worldwide. It is characterized by progressive neuronal degeneration and the accumulation of beta‐amyloid plaques (Aβ) ...
  • Cortical asymmetry in autosomal dominant Alzheimer's disease progression 
    Pérez-Millan, Agnès; Falgàs, Neus; Bosch, Beatriz; Borrego-Écija, Sergi; Antonell, Anna; Fernández-Villullas, Guadalupe; Esteller-Gauxax, Diana; Tort-Merino, Adrià; Bargalló, Núria; Balasa, Mircea; Lladó, Albert; Aguillon, David; Chrem Méndez, Patricio Alexis; Day, Gregory S.; Devenney, Emma; Huey, Edward D.; Ikeuchi, Takeshi; Jucker, Mathias; Kasuga, Kensaku; Dominantly Inherited Alzheimer Network (DIAN) (Oxford University Press, 2025-12-19)
    The cortical asymmetry index evaluates the cortical thickness asymmetry between hemispheres. We investigated cortical asymmetry index in asymptomatic and symptomatic mutation carriers of autosomal dominant Alzheimer's ...
  • Executive Functions in Latin American Older Adults: Exploring the Concept Shifting Test and Its Relationship with the APOE Gene in a Cross‐Sectional Sample from the LatAm‐FINGERS Study 
    Melillo Cardoso, Davi; Vasconcelos Friedlander, Clarisse; Sanches Yassuda, Monica; Cruz de Souza, Leonardo; Crivelli, Lucía; Kimie Suemoto, Claudia; Martin, Maria Eugenia; Calandri, Ismael Luis; Acosta‐Baena, Natalia; Surace, Ezequiel Ignacio; Damian, Andrés; Da Graça Morais Martin, Maria; Vigil‐Martinez, Ana; Henrique Cançado, Gustavo; Salinas‐Contreras, Rosa Maria; Custodio, Belen; Cusicanqui, María Isabel; Delgado, Carolina; Sevlever, Gustavo Emilio; Allegri, Ricardo Francisco (Wiley, 2025-12-26)
    Background Latin America (LA) faces high vulnerability to dementia risk factors. Early detection of cognitive decline, particularly in executive functions (EF), is crucial. The Trail Making Test (TMT) has limitations, ...
  • Cognitive and neuroimaging trajectories in the behavioral variant of Alzheimer's disease 
    Calandri, Ismael Luis; Phillips, Jeffrey S.; Tideman, Pontus; Singleton, Ellen Hanna; La Joie, Renaud; van der Flier, Wiesje M.; Jonkman, Laura E.; Hansson, Oskar; Rabinovici, Gil D.; Pijnenburg, Yolande A. L.; Ossenkoppele, Rik; Mastenbroek, Sophie E. (Wiley, 2025-12-26)
    Background The behavioral variant of Alzheimer's disease (bvAD) is a rare atypical presentationcharacterized by early and prominent behavioral changes, clinically akin to the behavioral variant of fronto‐temporal dementia ...
  • CADASIL Argentine Registry: Study Design and Preliminary Data 
    Ardohain Cristalli, Carolina Agata; Rosales, Julieta Soledad; Gonzalez, Fabio; Selvaggi, Valentin; Alonso, Julián Martín; López, Juan Ignacio; Aguilar, Martín Santiago; Kauffman, Marcelo; Saks, Danit G.; Allegri, Ricardo Francisco; Sevlever, Gustavo Emilio; Chaves, Hernán; Cristalli, Diana Olga; Calandri, Ismael Luis (Wiley, 2024)
    Background: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), the most common hereditary small vessel disease, leads to early-onset stroke and vascular cognitive ...
  • Clinical Validation of the SECONDs Tool for Evaluating Disorders of Consciousness in Argentina 
    Russo, María Julieta; Sampayo, María de la Paz; Arias, Paula; García, Vanina; Gambero, Yanina; Maiarú, Mariano; Deschle, Florencia; Pavón, Hernán (MDPI, 2025-10-07)
    Background: The Coma Recovery Scale-Revised (CRS-R) is the gold standard for diagnosing chronic disorders of consciousness (DoC); however, its clinical utility is limited by lengthy administration and the need for specialized ...
  • Associations of lifestyle factors with amyloid pathology in persons without dementia 
    Oomens, Julie E.; Vos, Stephanie Jb; Maserejian, Nancy N.; Boada, Mercè; Didic, Mira; Engelborghs, Sebastiaan; Fladby, Tormod; van der Flier, Wiesje M.; Frisoni, Giovanni B.; Fröhlich, Lutz; Gill, Kiran Dip; Grimmer, Timo; Hort, Jakub; Allegri, Ricardo Francisco; Alzheimer's Disease Neuroimaging Initiative (ADNI); A4 Study group; Dominantly Inherited Alzheimer Network (DIAN); European Prevention of Alzheimer's Dementia (EPAD) consortium, Fundació ACE Healthy Brain Initiative (FACEHBI); Japan Alzheimer's Disease Neuroimaging Initiative (J-ADNI), Korean Brain Aging Study for the Early Diagnosis and Prediction of Alzheimer's Disease (KBASE); Presymptomatic Evaluation of Experimental or Novel Treatments for Alzheimer's Disease (PREVENT-AD) research group (Sage, 2025-11-13)
    BackgroundThe association between lifestyle factors and Alzheimer's disease (AD) pathophysiology remains incompletely understood.ObjectiveThe aim of this study was to assess the association of alcohol consumption, smoking ...
  • Persistent neurological sequelae in children and adolescents after SARS-CoV-2: a scoping review 
    Zouari Mallouli, Salma; Munblit, Daniel; Iakovleva, Ekaterina; Winkler, Andrea Sylvia; Fornari, Arianna; Helbok, Raimund; Struhal, Walter; Beretta, Simone; De Groote, Wouter; Curatoli, Chiara; Lanza, Martina; Ericka, Fink; Crivelli, Lucía; Giussani, Giorgia; Wasay, Mohammad; Walha, Olfa Chakroun; Safi, Faiza; Leonardi, Matilde; Allegri, Ricardo Francisco; Guekht, Alla (Springer, 2025-10-31)
    Objectives: For the past five years, COVID-19 has not only been a priority for health planning but also a hotspot for clinical research. Yet, the weight of the worldwide COVID-19 pandemic arises from the critical phase ...
  • Comparative diagnostic performance of artificial intelligence models in structural MRI for schizophrenia: A systematic review and meta-analysis 
    Kotochinsky, Martin; Oliveira Fonseca, Pandora Eloa; Ramirez Lopera, Veronica; Mora, Laura; Wellgner Fernandes Oliveira, Amador; Cesar Teixeira Sirena, Eduardo; Bandeira de Melo Guimarães, Felipe; Lahitou Herlyn, Delfina; Norbu Sherpa, Nima; Gonzalez Lezana, Andrea; Pardini Fagundes, Thales (Elsevier, 2025-11-04)
    Introduction: Timely diagnosis of schizophrenia is essential to ensure prompt treatment initiation and adherence. Structural magnetic resonance imaging (sMRI), when combined with artificial intelligence (AI), offers a ...
  • Clinical and functional evidence supporting the pathogenicity of the novel PSEN1 p.R358P variant in early-onset Alzheimer's disease 
    García Chialva, Diego; Itzcovich, Tatiana; Cifarelli, Diego; Apecetche, Manuela; Chrem Méndez, Patricio; Magrath Guimet, Nahuel; Vázquez, Silvia; Bérgamo, Yanina; Allegri, Ricardo Francisco; Marazita, Mariela; Sevlever, Gustavo Emilio; Isaja, Luciana; Surace, Ezequiel Ignacio; Romorini, Leonardo (Sage, 2025-11-06)
    BackgroundPathogenic variants in PSEN1, PSEN2, or AβPP cause early-onset Alzheimer's disease (EOAD). Several novel variants remain of uncertain significance (VUS) due to limited evidence. The PSEN1 p.R358P variant has not ...
  • Síntomas de ansiedad y depresión en adultos con queja cognitiva subjetiva: impacto de la Pandemia COVID-19 
    Berrios, Waleska; Deschle, Florencia; Caporale, Sofía; Di Fonzo, Guido; Moreno, María Cecilia; Saglio, María Laura; Cervino, Cecilia Verónica; Povedano, Guillermo (Polemos, 2025-10-10)
    Introducción: La queja cognitiva subjetiva (QCS) se refiere a la percepción de alteraciones cognitivas en individuos con rendimiento normal en pruebas neuropsicológicas. Las QCS están asociadas con un mayor riesgo de ...
  • The potential for dementia prevention in Brazil: a population attributable fraction calculation for 14 modifiable risk factors 
    Suemoto, Claudia K.; Borelli, Wyllians V.; Calandri, Ismael Luis; Bertola, Laiss; Castilhos, Raphael M.; Caramelli, Paulo; Nitrini, Ricardo; Brucki, Sonia M. D.; Laks, Jerson; Mukadam, Naaheed; Livingston, Gill; Ferri, Cleusa P. (Elsevier, 2025-08-07)
    Background: The Lancet Commission on dementia prevention, intervention, and care 2024 updated the list of modifiable risk factors to include 14 factors. The potential for dementia prevention seems to be greater in low- and ...

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