Repositorio Dspace

ListarNeurociencias por tema "Apoptosis"

ListarNeurociencias por tema "Apoptosis"

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  • Acute severe hypoxia induces apoptosis of human pluripotent stem cells by a HIF-1α and P53 independent mechanism 
    Mucci, Sofía; Isaja, Luciana; Rodríguez Varela, María Soledad; Ferriol Laffouillere, Sofía Luján; Marazita, Mariela Claudia; Videla Richardson, Guillermo Agustín; Sevlever, Gustavo Emilio; Scassa, María Élida; Romorini, Leonardo (Nature Publishing Group, 2022-10-05)
    Human embryonic and induced pluripotent stem cells are self-renewing pluripotent stem cells (hPSCs) that can differentiate into a wide range of specialized cells. Although moderate hypoxia (5% O2) improves hPSC self-renewal, ...
  • Chemical hypoxia induces apoptosis of human pluripotent stem cells by a NOXA-mediated HIF-1α and HIF-2α independent mechanism 
    Isaja, Luciana; Mucci, Sofía; Vera, Jonathan; Rodríguez Varela, María Soledad; Marazita, Mariela Claudia; Morris-Hanon, Olivia; Videla Richardson, Guillermo Agustín; Sevlever, Gustavo Emilio; Scassa, María Élida; Romorini, Leonardo (Nature Publishing Group, 2020-10-26)
    Human embryonic and induced pluripotent stem cells (hESCs and hiPSCs) are self-renewing human pluripotent stem cells (hPSCs) that can differentiate to a wide range of specialized cells. Notably, hPSCs enhance their ...
  • GEMA—An Automatic Segmentation Method for Real-Time Analysis of Mammalian Cell Growth in Microfluidic Devices 
    Isa-Jara, Ramiro; Pérez-Sosa, Camilo; Macote-Yparraguirre, Erick; Revollo, Natalia; Lerner, Betiana; Miriuka, Santiago Gabriel; Delrieux, Claudio; Pérez, Maximiliano S.; Mertelsmann, Roland (MDPI, 2022-10-14)
    Nowadays, image analysis has a relevant role in most scientific and research areas. This process is used to extract and understand information from images to obtain a model, knowledge, and rules in the decision process. ...
  • Human embryonic stem cells display a pronounced sensitivity to the cyclin dependent kinase inhibitor Roscovitine 
    Videla Richardson, Guillermo Agustín; Furmento, Verónica Alejandra; García, Carolina Paola; Morris-Hanon, Olivia; Sevlever, Gustavo Emilio; Romorini, Leonardo; Scassa, María Élida (Biomed Central, 2019-08-28)
    BACKGROUND: The essentially unlimited expansion potential and the pluripotency of human embryonic stem cells (hESCs) make them attractive for cell-based therapeutic purposes. Although hESCs can indefinitely proliferate ...
  • Non-β-Blocking Carvedilol Analog, VK-II-86, Prevents Ouabain-Induced Cardiotoxicity 
    Gonano, Luis A.; Sepúlveda, Marisa; Morell, Malena; Toteff, Tamara; Racioppi, María Florencia; Lascano, Elena; Negroni, Jorge; Fernández Ruocco, María Julieta; Medei, Emiliano H.; Neiman, Gabriel; Miriuka, Santiago Gabriel; Back, Thomas G.; Wayne Chen, S.R.; Mattiazzi, Alicia; Vila Petroff, Martin (Japanese Circulation Society, 2018-12-25)
    Background: It has been shown that carvedilol and its non β-blocking analog, VK-II-86, inhibit spontaneous Ca2+ release from the sarcoplasmic reticulum (SR). The aim of this study is to determine whether carvedilol and ...

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