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Listar INEU.artículos por autor "Fagan, Anne M."

Listar INEU.artículos por autor "Fagan, Anne M."

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  • Autosomal dominant and sporadic late onset Alzheimer's disease share a common in vivo pathophysiology 
    Morris, John C.; Weiner, Michael W.; Xiong, Chengjie; Beckett, Laurel A.; Coble, Dean; Saito, Naomi; Aisen, Paul S.; Allegri, Ricardo Francisco; Benzinger, Tammie L.S.; Berman, Sarah B.; Cairns, Nigel; Carrillo, María C.; Chui, Helena C.; Chhatwal, Jasmeer P.; Cruchaga, Carlos; Fagan, Anne M.; Farlow, Martin R.; Fox, Nick C.; Ghetti, Bernardino; Goate, Alison M. (Oxford University Press, 2022-10-21)
    The extent to which the pathophysiology of autosomal dominant Alzheimer's disease corresponds to the pathophysiology of 'sporadic' late onset Alzheimer's disease is unknown, thus limiting the extrapolation of study findings ...
  • Change in Cerebrospinal Fluid Tau Microtubule Binding Region Detects Symptom Onset, Cognitive Decline, Tangles, and Atrophy in Dominantly Inherited Alzheimer's Disease 
    Horie, Kanta; Li, Yan; Barthélemy, Nicolas R.; Gordon, Brian A.; Hassenstab, Jason; Benzinger, Tammie L.S.; Fagan, Anne M.; Morris, John C.; Karch, Celeste M.; Xiong, Chengjie; Allegri, Ricardo Francisco; Chrem Méndez, Patricio Alexis; Ikeuchi, Takeshi; Kasuga, Kensaku; Noble, James M.; Farlow, Martin R.; Chhatwal, Jasmeer P.; Day, Gregory S.; Schofield, Peter R.; Dominantly Inherited Alzheimer Network (Wiley, 2023-03-16)
    Objective: Identifying cerebrospinal fluid measures of the microtubule binding region of tau (MTBR-tau) species that reflect tau aggregation could provide fluid biomarkers that track Alzheimer's disease related neurofibrillary ...
  • Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study 
    Boerwinkle, Anna H.; Gordon, Brian A.; Wisch, Julie K.; Flores, Shaney; Henson, Rachel L.; Butt, Omar H.; McKay, Nicole S.; Chen, Charles D.; Benzinger, Tammie L.S.; Fagan, Anne M.; Handen, Benjamin L.; Christian, Bradley T.; Head, Elizabeth; Mapstone, Mark; Rafii, Michael S.; Alzheimer's Biomarker Consortium-Down Syndrome; Dominantly Inherited Alzheimer Network; Allegri, Ricardo Francisco; Chrem Méndez, Patricio Alexis; Egido, Noelia (Elsevier, 2022-12-12)
    Background: Important insights into the early pathogenesis of Alzheimer's disease can be provided by studies of autosomal dominant Alzheimer's disease and Down syndrome. However, it is unclear whether the timing and spatial ...
  • Cross-sectional and longitudinal comparisons of biomarkers and cognition among asymptomatic middle-aged individuals with a parental history of either autosomal dominant or late-onset Alzheimer's disease 
    Xiong, Chengjie; McCue, Lena M.; Buckles, Virginia; Grant, Elizabeth; Agboola, Folasade; Coble, Dean; Bateman, Randall J.; Fagan, Anne M.; Benzinger, Tammie L.S.; Hassenstab, Jason; Schindler, Suzanne E.; McDade, Eric; Moulder, Krista L.; Gordon, Brian A.; Cruchaga, Carlos; Day, Gregory S.; Ikeuchi, Takeshi; Suzuki, Kazushi; Allegri, Ricardo Francisco; Dominantly Inherited Alzheimer Network (Wiley, 2023-01-14)
    Background: Comparisons of late-onset Alzheimer's disease (LOAD) and autosomal dominant AD (ADAD) are confounded by age. Methods: We compared biomarkers from cerebrospinal fluid (CSF), magnetic resonance imaging, and ...
  • Longitudinal clinical, cognitive and biomarker profiles in dominantly inherited versus sporadic early-onset Alzheimer's disease 
    Llibre Guerra, Jorge J.; Iaccarino, Leonardo; Coble, Dean; Edwards, Lauren; Li, Yan; McDade, Eric; Strom, Amelia; Gordon, Brian A.; Mundada, Nidhi; Schindler, Suzanne E.; Tsoy, Elena; Ma, Yinjiao; Lu, Ruijin; Fagan, Anne M.; Benzinger, Tammie L.S.; Soleimani Meigooni, David; Aschenbrenner, Andrew J.; Allegri, Ricardo Francisco; Patricio Alexis, Chrem Méndez; Surace, Ezequiel Ignacio (Oxford University Press, 2023-10-18)
    Approximately 5% of Alzheimer's disease cases have an early age at onset (<65 years), with 5-10% of these cases attributed to dominantly inherited mutations and the remainder considered as sporadic. The extent to which ...
  • Multimodal brain age estimates relate to Alzheimer disease biomarkers and cognition in early stages: a cross-sectional observational study 
    Millar, Peter R.; Gordon, Brian A.; Luckett, Patrick H.; Benzinger, Tammie L.S.; Cruchaga, Carlos; Fagan, Anne M.; Hassenstab, Jason; Perrin, Richard J.; Schindler, Suzanne E.; Allegri, Ricardo Francisco; Day, Gregory S.; Farlow, Martin R.; Mori, Hiroshi; Nübling, Georg; Dominantly Inherited Alzheimer Network; Bateman, Randall J.; Morris, John C.; Ances, Beau M. (eLife Sciences Publications, 2023-01-06)
    Background: Estimates of 'brain-predicted age' quantify apparent brain age compared to normative trajectories of neuroimaging features. The brain age gap (BAG) between predicted and chronological age is elevated in symptomatic ...

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