• Ideas erróneas sobre daño cerebral adquirido en población de la Ciudad Autónoma de Buenos Aires 

  Tabernero, María Eugenia; Leonardelli, Eduardo; Gallo, María Fernanda; Cores, Evangelina Valeria; Deschle, Florencia (Elsevier, 2024-10-10)

  Introducción Diversas investigaciones han demostrado la existencia de ideas erróneas sobre daño cerebral adquirido (ieDCA) y sus consecuencias en diferentes poblaciones. Objetivo Describir la presencia de ieDCA en ...
• CSF proteomics identifies early changes in autosomal dominant Alzheimer's disease 

  Shen, Yuanyuan; Timsina, Jigyasha; Heo, Gyujin; Beric, Aleksandra; Ali, Muhammad; Wang, Ciyang; Yang, Chengran; Wang, Yueyao; Western, Daniel; Liu, Menghan; Gorijala, Priyanka; Budde, John; Do, Anh; Liu, Haiyan; Gordon, Brian; Llibre Guerra, Jorge J.; Surace, Ezequiel Ignacio; Allegri, Ricardo Francisco; Dominantly Inherited Alzheimer Network (Cell Press, 2024-09-26)

  In this high-throughput proteomic study of autosomal dominant Alzheimer's disease (ADAD), we sought to identify early biomarkers in cerebrospinal fluid (CSF) for disease monitoring and treatment strategies. We examined CSF ...
• Nuevos criterios diagnósticos clínico y neuropatológicos de la encefalopatía traumática crónica: una revisión narrativa 

  Russo, María Julieta; Salvat, Fernando; Allegri, Ricardo Francisco; Sevlever, Gustavo Emilio (Polemos, 2024-10-20)

  La encefalopatía traumática crónica es una enfermedad neurodegenerativa resultante de la acumulación de numerosos traumatismos craneoencefálicos, para la cual no existe un diagnóstico en vida definitivo ni un tratamiento ...
• Comparative accuracy of Mini-Linguistic State Examination, Addenbrooke's Cognitive Examination, and Depistage Cognitif de Quebec for the diagnosis of primary progressive aphasia 

  Fernández Romero, Lucía; Morello García, Florentina; Laforce Jr, Robert; Delgado Alonso, Cristina; Delgado Álvarez, Alfonso; Gil Moreno, María José; Lavoie, Monica; Cuetos, Fernando; Matias Guiu, Jordi A.; Matias Guiu, Jorge (SAGE, 2024-10-17)

  Background: Clinical diagnosis in primary progressive aphasia (PPA) is challenging. Recently, emphasis has been placed on the importance of screening evaluation. Three different screening tests that use different strategies ...
• Country-level gender inequality is associated with structural differences in the brains of women and men 

  Zugman, Andre; Alliende, Luz María; Medel, Vicente; A I Bethlehem, Richard; Seidlitz, Jakob; Ringlein, Grace; Arango, Celso; Arnatkevičiūtė, Aurina; Asmal, Laila; Bellgrove, Mark; Benegal, Vivek; Bernardo, Miquel; Billeke, Pablo; Bosch-Bayard, Jorge; Bressan, Rodrigo; Busatto, Geraldo F.; Castro, Mariana Nair; Chaim-Avancini, Tiffany; Compte, Albert; Villarreal, Mirta Fabiana (National Academy of Sciences, 2023-05-16)

  Gender inequality across the world has been associated with a higher risk to mental health problems and lower academic achievement in women compared to men. We also know that the brain is shaped by nurturing and adverse ...
• EFFECTS OF BACTERIAL LIPOPOLYSACCHARIDE AND SHIGA TOXIN ON INDUCED PLURIPOTENT STEM CELL-DERIVED MESENCHYMAL STEM CELLS 

  Martire-Greco, Daiana; La Greca, Alejandro; Castillo Montañez, Luis; Biani, María Celeste; Lombardi, Antonella; Birnberg-Weiss, Federico; Norris, Alessandra; Sacerdoti, Flavia; Amaral, María Marta; Rodrigues-Rodriguez, Nahuel; Pittaluga, Jose Ramón; Furmento, Verónica Alejandra; Landoni, Verónica Inés; Miriuka, Santiago Gabriel; Luzzani, Carlos Daniel; Fernández, Gabriela Cristina (Lippincott Williams & Wilkins, 2023-04-11)

  Background : Mesenchymal stem cells (MSCs) can be activated by different bacterial toxins. Lipopolysaccharides and Shiga Toxin (Stx) are the main toxins necessary for hemolytic uremic syndrome development. The main etiological ...
• Peritumoral adipose tissue promotes lipolysis and white adipocytes browning by paracrine action 

  Pagnotta, Priscila; Gantov, Mariana; Fletcher, Sabrina; Lombardi, Antonella; Crosbie, María Lujan; Santiso, Natalia; Ursino, Anabela; Frascarolli, Celeste; Amato, Alicia; Dreszman, Rubén; Calvo, Juan Carlos; Toneatto, Judith (Frontiers Research Foundation, 2023-04-26)

  Background: Stromal adipocytes and tumor breast epithelial cells undergo a mutual metabolic adaptation within tumor microenvironment. Therefore, browning and lipolysis occur in cancer associated adipocytes (CAA). However, ...
• Childhood adversity modulates structural brain changes in borderline personality but not in major depression disorder. 

  Camacho Téllez, Vicente; Castro, Mariana Nair; Wainsztein, Agustina Edith; Goldberg, Ximena; De Pino, Gabriela; Costanzo, Elsa; Cardoner, Narcís; Menchón, José Manuel; Soriano-Mas, Carles; Guinjoan, Salvador Martín; Villarreal, Mirta Fabiana (Elsevier, 2024-03-01)

  Adverse childhood experiences (ACEs) negatively affect the function and structure of emotion brain circuits, increasing the risk of various psychiatric disorders. It is unclear if ACEs show disorder specificity with respect ...
• A miR-137-Related Biological Pathway of Risk for Schizophrenia Is Associated With Human Brain Emotion Processing 

  Pergola, Giulio; Rampino, Antonio; Sportelli, Leonardo; Borcuk, Christopher James; Passiatore, Roberta; Di Carlo, Pasquale; Marakhovskaia, Aleksandra; Fazio, Leonardo; Amoroso, Nicola; Castro, Mariana Nair; Domenici, Enrico; Gennarelli, Massimo; Khlghatyan, Jivan; Christos Kikidis, Gianluca; Lella, Annalisa; Magri, Chiara; Monaco, Alfonso; Papalino, Marco; Parihar, Madhur; Popolizio, Teresa (Elsevier, 2023-11-22)

  Background: miR-137 is a microRNA involved in brain development, regulating neurogenesis and neuronal maturation. Genome-wide association studies have implicated miR-137 in schizophrenia risk but do not explain its involvement ...
• Longitudinal clinical, cognitive and biomarker profiles in dominantly inherited versus sporadic early-onset Alzheimer's disease 

  Llibre Guerra, Jorge J.; Iaccarino, Leonardo; Coble, Dean; Edwards, Lauren; Li, Yan; McDade, Eric; Strom, Amelia; Gordon, Brian A.; Mundada, Nidhi; Schindler, Suzanne E.; Tsoy, Elena; Ma, Yinjiao; Lu, Ruijin; Fagan, Anne M.; Benzinger, Tammie L.S.; Soleimani Meigooni, David; Aschenbrenner, Andrew J.; Allegri, Ricardo Francisco; Patricio Alexis, Chrem Méndez; Surace, Ezequiel Ignacio (Oxford University Press, 2023-10-18)

  Approximately 5% of Alzheimer's disease cases have an early age at onset (<65 years), with 5-10% of these cases attributed to dominantly inherited mutations and the remainder considered as sporadic. The extent to which ...
• PluriBAC: A Versatile Baculovirus-Based Modular System to Express Heterologous Genes in Different Biotechnological Platforms 

  Amorós Morales, Leslie C.; Marchesini, Abril; Gómez Bergna, Santiago M.; García Fallit, Matías; Tongiani, Silvana E.; Vásquez, Larisa; Ferrelli, María Leticia; Videla Richardson, Guillermo Agustín; Candolfi, Marianela; Romanowski, Víctor; Pidre, Matías L. (MDPI, 2023-09-23)

  Baculoviruses are insect-specific pathogens widely used in biotechnology. In particular, the Autographa californica nucleopolyhedrovirus (AcMNPV) has been exploited as a platform for bio-inputs production. This is why the ...
• Role of hydroxymethylglutharyl-coenzyme A reductase in the induction of stem-like states in breast cancer 

  Marks, María Paula; Giménez, Carla Alejandra; Isaja, Luciana; Vera, Mariana Belén; Borzone, Francisco Raúl; Pereyra-Bonnet, Federico; Romorini, Leonardo; Videla Richardson, Guillermo Agustín; Chasseing, Norma Alejandra; Calvo, Juan Carlos; Vellón, Luciano (Springer-Verlag, 2024-02-28)

  Purpose: De novo synthesis of cholesterol and its rate-limiting enzyme, 3-hydroxy-3-methylglutharyl-coenzyme A reductase (HMGCR), is deregulated in tumors and critical for tumor cell survival and proliferation. However, ...
• Therapeutic Potential in Wound Healing of Allogeneic Use of Equine Umbilical Cord Mesenchymal Stem Cells 

  Iribarne, Ailén; Palma, María Belén; Andrini, Laura B.; Riccillo, Fernando; Rodríguez, Delfina; Casella, Martín; Garay, Felipe; Spoto Zabala, Julieta; Mazza, Leandro; Muro, Adriana; Buero, Guillermo; Miriuka, Santiago Gabriel; Carosella, Edgardo D.; García, Marcela N. (MDPI, 2024-02-16)

  Wound healing after skin injury is a complex process, particularly in equines where leg wounds are prevalent and their repair is complicated due to the anatomical characteristics. Conventional treatments are not effective ...
• Alzheimer's polygenic risk scores are associated with cognitive phenotypes in Down syndrome 

  Gorijala, Priyanka; Aslam, M. Muaaz; Dang, Lam-Ha T.; Xicota, L.; Fernández, María V.; Sung, Yun Ju; Fan, Kang-Hsien; Feingold, Eleanor; Surace, Ezequiel Ignacio; Chhatwal, Jasmeer P.; Hom, Christy L.; Dominantly Inherited Alzheimer Network; NIA-LOAD family study, for the Alzheimer's Biomarkers Consortium-Down Syndrome (ABC-DS) Investigators; Hartley, Sigan L.; Hassenstab, Jason; Perrin, Richard J.; Mapstone, Mark; Zaman, Shahid H.; Ances, Beau M.; Kamboh, M. Ilyas; Lee, Joseph H.; Cruchaga, Carlos (John Wiley & Sons, 2023-10-19)

  Introduction: This study aimed to investigate the influence of the overall Alzheimer's disease (AD) genetic architecture on Down syndrome (DS) status, cognitive measures, and cerebrospinal fluid (CSF) biomarkers. Methods: ...
• Broad-Spectrum Antiviral Effect of Cannabidiol Against Enveloped and Nonenveloped Viruses 

  Marquez, Agostina B.; Vicente, Josefina; Castro, Eliana; Vota, Daiana; Rodríguez Varela, María Soledad; Lanza Castronuovo, Priscila A.; Fuentes, Giselle M.; Parise, Alejandro R.; Romorini, Leonardo; Alvarez, Diego E.; Bueno, Carlos A.; Ramirez, Cristina L.; Alaimo, Agustina; García, Cybele C. (Mary Ann Liebert, 2023-09-08)

  Introduction: Cannabidiol (CBD), the main non-psychoactive cannabinoid of the Cannabis sativa plant, is a powerful antioxidant compound that in recent years has increased interest due to causes effects in a wide range of ...
• Teaching NeuroImage: Shrimp Sign in Ataxic Cerebellar Progressive Multifocal Leukoencephalopathy 

  Varela, Francisco José; Chaves, Hernán; Rossi, Malco Damián (Lippincott Williams & Wilkins, 2023-08-31)

  Resumen no disponible
• Mitochondrial Peptide Humanin Facilitates Chemoresistance in Glioblastoma Cells 

  Peña Agudelo, Jorge A.; Pidre, Matías L.; García Fallit, Matías; Pérez Küper, Melanie; Zuccato, Camila; Nicola Candia, Alejandro J.; Marchesini, Abril; Vera, Mariana Belén; De Simone, Emilio; Giampaoli, Carla; Amorós Morales, Leslie C.; Gonzalez, Nazareno; Romanowski, Víctor; Videla Richardson, Guillermo Agustín; Seilicovich, Adriana; Candolfi, Marianela (MDPI, 2023-08-11)

  Humanin (HN) is a mitochondrial-derived peptide with robust cytoprotective effects in many cell types. Although the administration of HN analogs has been proposed to treat degenerative diseases, its role in the pathogenesis ...
• Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer's disease 

  Johnson, Erik C. B.; Bian, Shijia; Haque, Rafi U.; Carter, E. Kathleen; Watson, Caroline M.; Gordon, Brian A.; Ping, Lingyan; Duong, Duc M.; Epstein, Michael P.; McDade, Eric; Barthélemy, Nicolas R.; Karch, Celeste M.; Xiong, Chengjie; Cruchaga, Carlos; Perrin, Richard J.; Wingo, Aliza P.; Dominantly Inherited Alzheimer Network (Nature Publishing Company, 2023-08-07)

  Alzheimer's disease (AD) pathology develops many years before the onset of cognitive symptoms. Two pathological processes-aggregation of the amyloid-β (Aβ) peptide into plaques and the microtubule protein tau into ...
• Effectiveness of cognitive rehabilitation on mild cognitive impairment using teleneuropsychology 

  Martínez Canyazo, Carlos; Keller, Greta; Helou, María Belén; Arruabarrena, Micaela María; Corvalán, Nicolás; Carello, María Agostina; Harris, Paula; Feldman, Mónica; Fernández, Rodrigo Sebastián; Calandri, Ismael Luis; Martin, María Eugenia; Allegri, Ricardo Francisco; Crivelli, Lucía (Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento, 2023-07-24)

  The COVID-19 pandemic has affected the continuity of cognitive rehabilitation worldwide. However, the use of teleneuropsychology to provide cognitive rehabilitation has contributed significantly to the continuity of the ...
• Clinical correlates of fear of falling in progressive supranuclear palsy and multiple system atrophy 

  Martínez Villota, Viviana Alexandra; Terroba Chambi, Cinthia; Castillo Torres, Sergio Andrés; Rossi, Malco Damián; Merello, Marcelo (Wiley, 2023-05-14)

  Background and purpose: Clinical correlates of fear of falling (FoF) are scarcely studied in patients with progressive supranuclear palsy (PSP) and multiple system atrophy (MSA). This study was undertaken to evaluate the ...

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