INEU.artículos: Recent submissions

  • Comparing cortical signatures of atrophy between late-onset and autosomal dominant Alzheimer disease 
    Allegri, Ricardo Francisco; Dincer, Aylin; Gordon, Brian A.; Hari-Raj, Amrita; Keefe, Sarah J.; Flores, Shaney; McKay, Nicole S.; Paulick, Angela M.; Shady Lewis, Kristine E.; Feldman, Rebecca L.; Hornbeck, Russ C.; Ances, Beau M.; Berman, Sarah B.; Brickman, Adam M.; Brooks, William S.; Cash, David M.; Chhatwal, Jasmeer P.; Farlow, Martin R.; La Fougère, Christian; Fox, Nick C.; Fulham, Michael J.; Jack Jr, Clifford R.; Joseph-Mathurin, Nelly; Karch, Celeste M.; Lee, Athene; Levin, Johannes; Masters, Colin L.; McDade, Eric; Oh, Hwamee; Perrin, Richard J.; Raji, Cyrus; Salloway, Stephen; Schofield, Peter R.; Su, Yi; Villemagne, Victor L.; Wang, Qing; Weiner, Michael W.; Xiong, Chengjie; Yakushev, Igor; Morris, John C.; Bateman, Randall J.; Benzinger, Tammie L.S.; Dominantly Inherited Alzheimer Network (Elsevier, 2020-11-05)
    Defining a signature of cortical regions of interest preferentially affected by Alzheimer disease (AD) pathology may offer improved sensitivity to early AD compared to hippocampal volume or mesial temporal lobe alone. Since ...
  • Impact of Social Isolation on People with Dementia and Their Family Caregivers 
    Dos Santos Azevedo, Lílian Viana; Calandri, Ismael Luis; Slachevsky, Andrea; Graviotto, Héctor Gastón; Santos Vieira, Maria Carolina; Bezerra de Andrade, Caíssa; Peredo Rossetti, Adriana; Barroso Generoso, Alana; Carvalho Carmona, Karoline; Aparecida Cardoso Pinto, Ludmilla; Sorbara, Marcos; Pinto, Alejandra; Guajardo, Tania; Olavarría, Loreto; Thumala, Daniela; Crivelli, Lucía; Vivas, Ludmila; Allegri, Ricardo Francisco; Tonidandel Barbosa, Maira; Serrano, Cecilia M. (IOS, 2021-03-30)
    Background: People with dementia and their family caregivers may face a great burden through social isolation due to the COVID-19 pandemic, which can be manifested as various behavioral and clinical symptoms. Objective: ...
  • Living with dementia: increased level of caregiver stress in times of COVID-19 
    Cohen, Gabriela; Russo, María Julieta; Campos, Jorge; Allegri, Ricardo Francisco (Cambridge University Press, 2020-11)
    COVID-19 pandemic in Argentina has affected the care of older adults with dementia deeply. Our objective was to study how the obligatory social isolation affected stress caregiver and burden of care of family members of ...
  • Utility of a Spanish version of Three Words-Three Shapes Test to detect memory impairment in primary progressive aphasia 
    Calandri, Ismael Luis; Crivelli, Lucía; Morello García, Florentina; Allegri, Ricardo Francisco (Taylor & Frances, 2021-04-09)
    Introduction: Three Words-Three Shapes (3W3S) is a bedside test that assesses verbal and non-verbal memory and has proven useful in staging memory decline in amnestic disorders and primary progressive aphasia. Given its ...
  • Generation of a human induced pluripotent stem cell line from a familial Alzheimer's disease PSEN1 T119I patient 
    Isaja, Luciana; Rodríguez Varela, María Soledad; Marazita, Mariela Claudia; Mucci, Sofía; Itzcovich, Tatiana; Chrem Méndez, Patricio Alexis; Niikado, Matías; Ferriol Laffouillere, Sofía Luján; Allegri, Ricardo Francisco; Martinetto, Horacio; Sevlever, Gustavo Emilio; Scassa, María Élida; Surace, Ezequiel Ignacio; Romorini, Leonardo (Elsevier, 2021-04-05)
    Human induced pluripotent stem cells (hiPSC) line FLENIi001-A was reprogrammed from dermal fibroblasts using the lentiviral-hSTEMCCA-loxP vector. Fibroblasts were obtained from a skin biopsy of a 72-year-old Caucasian male ...
  • Diagnostic accuracy of the UDS 3.0 neuropsychological battery in a cohort with Alzheimer's disease in Colombia 
    Porto, Maria F.; Benitez Agudelo, Juan Camilo; Aguirre Acevedo, Daniel Camilo; Barceló Martínez, Ernesto; Allegri, Ricardo Francisco (Taylor & Francis, 2021-03-24)
    Background: Alzheimer's disease (AD) is a neurodegenerative disease that causes a gradual loss of cognitive functions and limits daily activities performance. Early diagnosis of AD is essential to start timely treatment. ...
  • Brain volumes quantification from MRI in healthy controls: Assessing correlation, agreement and robustness of a convolutional neural network-based software against FreeSurfer, CAT12 and FSL 
    Chaves, Hernán; Dorr, Francisco; Costa, Martín Elías; Serra, María Mercedes; Fernández Slezak, Diego; Farez, Mauricio Franco; Sevlever, Gustavo Emilio; Yáñez, Paulina; Cejas, Claudia Patricia (Masson, 2020-10-01)
    Background and purpose: There are instances in which an estimate of the brain volume should be obtained from MRI in clinical practice. Our objective is to calculate cross-sectional robustness of a convolutional neural ...
  • Distinct Neural Processing of Acute Stress in Major Depression and Borderline Personality Disorder 
    Villarreal, Mirta Fabiana; Wainsztein, Agustina Edith; Álvarez Mercé, Rocío; Goldberg, Ximena; Castro, Mariana Nair; Brusco, Luis Ignacio; Ladrón de Guevara, Soledad; Bodurka, Jerzy; Paulus, Martin; Menchón, José Manuel; Soriano-Mas, Carles; Guinjoan, Salvador Martín (Elsevier, 2021-02-26)
    Background: Major depressive disorder (MDD) and borderline personality disorder (BPD) are highly prevalent and often comorbid psychiatric conditions, with abnormal processing of negative affect resulting from psychological ...
  • Environmental factors between normal and superagers in an Argentine cohort 
    Calandri, Ismael Luis; Crivelli, Lucía; Martin, María Eugenia; Egido, Noelia; Magrath Guimet, Nahuel (Associação Neurologia Cognitiva e do Comportamento, 2020-12-14)
    Normal aging usually brings age-related cognitive decline. However, there is a group of aged individuals who have exceptional memory performance: the superagers. Objective: Our aim was to identify the environmental ...
  • The impact of an early strict nationwide lockdown on the pattern of consultation for neurological diseases 
    Calandri, Ismael Luis; Hawkes, Maximiliano Alberto; Marrodán, Mariano; Ameriso, Sebastián Francisco; Allegri, Ricardo Francisco (Elsevier, 2020-10-15)
  • Extraction-free protocol combining proteinase K and heat inactivation for detection of SARS-CoV-2 by RT-qPCR 
    Genoud, Valeria; Stortz, Martin; Waisman, Ariel; Berardino, Bruno G.; Verneri, Paula; Dansey, Virginia; Salvatori, Melina; Remes Lenicov, Federico; Levi, Valeria (PLoS One, 2021-02-26)
    Real-time reverse transcription PCR (RT-qPCR) is the gold-standard technique for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection in nasopharyngeal swabs specimens. The analysis by RT-qPCR usually ...
  • Towards the Journal of Applied Cognitive Neuroscience 
    Allegri, Ricardo Francisco; Roman, Fabián; Barceló Martínez, Ernesto (Universidad de la Costa, 2020-12-07)
    In his book The Structure of Science Evolution, Thomas Khum defines a paradigmas “a set of beliefs, values and accepted techniques that define the exercise of a scientific discipline”. A new paradigm is a change of vision, ...
  • Moving from neurodegenerative dementias, to cognitive proteinopathies, replacing "where" by "what"… 
    Allegri, Ricardo Francisco (Associação Neurologia Cognitiva e do Comportamento, 2020-07)
    Neurodegenerative dementias have been described based on their phenotype, in relation to selective degeneration occurring in a particular neuroanatomical system. More recently however, the term proteinopathy has been ...
  • La investigación y los investigadores clínicos continúan huérfanos en el sistema nacional de ciencia y técnica… 
    Allegri, Ricardo Francisco (Fundación Revista Medicina (Buenos Aires), 2020-07)
  • Neural and subjective effects of inhaled N,N-dimethyltryptamine in natural settings 
    Pallavicini, Carla; Cavanna, Federico; Zamberlan, Federico; de la Fuente, Laura A.; Ilksoy, Yayla; Perl, Yonatan Sanz; Arias, Mauricio; Romero, Celeste; Carhart-Harris, Robin; Timmermann, Christopher; Tagliazucchi, Enzo (Sage, 2021-02-10)
    Background: N,N-dimethyltryptamine is a short-acting psychedelic tryptamine found naturally in many plants and animals. Few studies to date have addressed the neural and psychological effects of N,N-dimethyltryptamine ...
  • Structural brain abnormalities in schizophrenia in adverse environments: examining the effect of poverty and violence in six Latin American cities 
    Crossley, Nicolas; Zugman, Andre; Reyes-Madrigal, Francisco; Czepielewski, Leticia; Castro, Mariana Nair; Diaz-Zuluaga, Ana María; Pineda-Zapata, Julián; Reckziegel, Ramiro; Gadelha, Ary; Jackowski, Andrea; Noto, Cristiano; Alliende Serra, Luz Maria; Iruretagoyena, Bárbara; Ossandon, Tomas; Ramirez-Mahaluf, Juan Pablo; Castañeda, Carmen Paz; Gonzalez-Valderrama, Alfonso; Nachar, Rubén; Guinjoan, Salvador Martín; ANDES Network (Cambridge University Press, 2020-08-18)
    Background Social and environmental factors such as poverty or violence modulate the risk and course of schizophrenia. However, how they affect the brain in patients with psychosis remains unclear. Aims We studied how ...
  • Automatic and unbiased segmentation and quantification of myofibers in skeletal muscle 
    Waisman, Ariel; Norris, Alessandra; Costa, Martín Elías; Kopinke, Daniel (Nature Publishing Group, 2021-01-22)
    Skeletal muscle has the remarkable ability to regenerate. However, with age and disease muscle strength and function decline. Myofiber size, which is affected by injury and disease, is a critical measurement to assess ...
  • HLA-G gene editing: a novel therapeutic alternative in cancer immunotherapy 
    Palma, María Belén; Tronik-Le Roux, Diana; Amín, Guadalupe; Castañeda, Sheila; Möbbs, Alan Miqueas; Scarafía, María Agustina; La Greca, Alejandro; Daouya, Marina; Poras, Isabelle; Inda, Ana María; Moro, Lucía Natalia; Carosella, Edgardo D.; García, Marcela N.; Miriuka, Santiago Gabriel (bioRxiv, 2021-01-22)
    Cancer immunotherapies based mainly on the blockade of immune-checkpoint (IC) molecules by anti-IC antibodies offer new alternatives for treatment in oncological diseases. However, a considerable proportion of patients ...
  • miR-302 family, miR-145 and miR-296 temporal expression profile along the cell cycle of human pluripotent stem cells 
    Rodríguez Varela, María Soledad; Mucci, Sofía; Videla Richardson, Guillermo Agustín; Isaja, Luciana; Sevlever, Gustavo Emilio; Scassa, María Élida; Romorini, Leonardo (Elsevier, 2021-01-21)
    Human pluripotent stem cells (hPSCs), like embryonic (hESCs) and induced pluripotent stem cells (hiPSCs), exhibit an unusual cell cycle structure characterized by a short G1 phase and cells being most of time in S phase. ...
  • Downregulation of E-cadherin in pluripotent stem cells triggers partial EMT 
    Aban, Cyntia; Lombardi, Antonella; Neiman, Gabriel; Biani, María Celeste; La Greca, Alejandro; Waisman, Ariel; Moro, Lucía Natalia; Sevlever, Gustavo Emilio; Miriuka, Santiago Gabriel; Luzzani, Carlos Daniel (Nature Publishing Group, 2021-01-21)
    Epithelial to mesenchymal transition (EMT) is a critical cellular process that has been well characterized during embryonic development and cancer metastasis and it also is implicated in several physiological and pathological ...

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