INEU.artículos: Recent submissions

  • Myostatin gene editing by CRISPR/Cas9 technology of Brangus fetal fibroblasts to produce edited embryos by cloning 
    Bastón, Juan Ignacio; Viale, Diego Luis; Olguín, Martín; Wiedenmann, Elisabet; Arnold, Victoria; Suva, Mariana; Luzzani, Carlos Daniel; Miriuka, Santiago Gabriel; Moro, Lucía Natalia; Vichera, Gabriel (Csiro Publishing, 2021-01-08)
    Some European cattle breeds, such as Charolais and Maine Anjou, have natural mutations in the myostatin gene (MSTN) that inhibit its expression and result in an increase in muscle mass and protein content. An innovative ...
  • White matter fiber density abnormalities in cognitively normal adults at risk for late-onset Alzheimer's disease 
    Sánchez, Stella Maris; Duarte-Abritta, Bárbara; Abulafia, Carolina; De Pino, Gabriela; Bocaccio, Hernán; Castro, Mariana Nair; Sevlever, Gustavo Emilio; Fonzo, Greg A.; Nemeroff, Charles B.; Gustafson, Deborah R.; Guinjoan, Salvador Martín; Villarreal, Mirta Fabiana (Elsevier, 2020-02)
    Tau accumulation affecting white matter tracts is an early neuropathological feature of late-onset Alzheimer's disease (LOAD). There is a need to ascertain methods for the detection of early LOAD features to help with ...
  • Meditation Increases the Entropy of Brain Oscillatory Activity 
    Martínez Vivot, Rocío; Pallavicini, Carla; Zamberlan, Federico; Vigo, Daniel Eduardo; Tagliazucchi, Enzo (Elsevier, 2020-04-01)
    We address the hypothesis that the entropy of neural dynamics indexes the intensity and quality of conscious content. Previous work established that serotonergic psychedelics can have a dysregulating effect on brain activity, ...
  • PIWI-interacting RNAs are differentially expressed during cardiac differentiation of human pluripotent stem cells 
    La Greca, Alejandro; Scarafía, María Agustina; Hernández Cañás, María Clara; Pérez, Nelba; Castañeda, Sheila; Colli, Carolina; Miqueas Möbbs, Alan; Santín Velazque, Natalia Lucía; Neiman, Gabriel; Garate, Ximena; Aban, Cyntia; Waisman, Ariel; Moro, Lucía Natalia; Sevlever, Gustavo Emilio; Luzzani, Carlos Daniel; Miriuka, Santiago Gabriel (Public Library of Science, 2020-05-05)
    PIWI-interacting RNAs (piRNAs) are a class of non-coding RNAs initially thought to be restricted exclusively to germline cells. In recent years, accumulating evidence has demonstrated that piRNAs are actually expressed in ...
  • Comment on: The Geographic Diversity of Spinocerebellar Ataxias (SCAs) in the Americas 
    Guarnaschelli, Marlen; Rossi, Malco Damián; Zajd, Ana; Igarreta, Pilar (Wiley, 2020-01-25)
    Resumen no disponible
  • A novel mutation in PSEN1 (p.Arg41Ser) in an Argentinian woman with early onset Parkinsonism 
    Gatto, Emilia M.; Rojas, Galeno J.; Nemirovsky, Sergio I.; Da Prat, Gustavo; Persi, Gabriel; Cesarini, Martin; Etcheverry, Jose L.; Gonzalez Rojas, Natalia; Parisi, Virginia; Cordoba, Marta; Sevlever, Gustavo Emilio; Allegri, Ricardo Francisco; Turjanski, Adrian G. (Elsevier, 2020-08)
    Introduction: Mutations in presenilin-1 (PSEN1) account for the majority of cases of familial autosomal dominant early-onset Alzheimer's disease (AD) as well as in sporadic forms. Atypical presentations are reported including ...
  • Disrupted functional connectivity of the locus coeruleus in healthy adults with parental history of Alzheimer's disease 
    Del Cerro, Inés; Villarreal, Mirta Fabiana; Abulafia, Carolina; Duarte-Abritta, Bárbara; Sánchez, Stella Maris; Castro, Mariana Nair; Bocaccio, Hernán; Ferrer, Isidre; Menchón, José Manuel; Sevlever, Gustavo Emilio; Nemeroff, Charles B.; Soriano-Mas, Carles; Guinjoan, Salvador Martín (Pergamon Press, 2020-04)
    Prevention and early treatment strategies for Alzheimer's disease (AD) are hampered by the lack of research biomarkers. Neuropathological changes in the Locus Coeruleus (LC) are detected early in AD, and noradrenaline plays ...
  • Structural brain abnormalities in schizophrenia in adverse environments: examining the effect of poverty and violence in six latin american cities 
    Crossley, Nicolas; Zugman, Andre; Reyes-Madrigal, Francisco; Czepielewski, Leticia; Castro, Mariana Nair; Diaz-Zuluaga, Ana María; Pineda-Zapata, Julián; Reckziegel, Ramiro; Gadelha, Ary; Jackowski, Andrea; Noto, Cristiano; Alliende Serra, Luz Maria; Iruretagoyena, Bárbara; Ossandon, Tomas; Ramirez-Mahaluf, Juan Pablo; Castañeda, Carmen Paz; Gonzalez-Valderrama, Alfonso; Nachar, Rubén; León-Ortiz, Pablo; Undurraga, Juan; Lopez-Jaramillo, Carlos; Guinjoan, Salvador Martín; Gama, Clarissa; De la Fuente-Sandoval, Camilo; Bressan, Rodrigo (Oxford University Press, 2020-04)
    Background Social and environmental factors such as poverty or violence, modulate the risk and course of schizophrenia, but how they affect the brain in patients with psychosis remains unclear. We here studied how they ...
  • Neuropsychological profile of Alzheimer’s disease based on amyloid biomarker findings results from a South American cohort. Appl Neuropsychol Adult 1–6. 
    Clarens, María Florencia; Crivelli, Lucía; Calandri, Ismael Luis; Chrem Méndez, Patricio Alexis; Martín, María Eugenia; Russo, María Julieta; Campos, Jorge; Surace, Ezequiel Ignacio; Vázquez, Silvia; Sevlever, Gustavo Emilio; Allegri, Ricardo Francisco (Taylor & Francis Group, 2020-04-30)
    Objective: Increased life expectancy and exponential growth of adults suffering from Alzheimer's disease (AD) worldwide, has led to biomarkers incorporation for diagnosis in early stages. Use of neuropsychological testing ...
  • Prognostic value of ATN Alzheimer biomarkers: 60-month follow-up results from the Argentine Alzheimer’s Disease Neuroimaging Initiative. 
    Allegri, Ricardo Francisco; Chrem Méndez, Patricio Alexis; Calandri, Ismael Luis; Cohen, Gabriela; Martín, María Eugenia; Russo, María Julieta; Crivelli, Lucía; Pertierra, Lucía; Tapajóz Pereira de Sampaio, Fernanda; Clarens, María Florencia; Campos, Jorge; Nahas, Federico Ezequiel; Vázquez, Silvia; Surace, Ezequiel Ignacio; Sevlever, Gustavo Emilio (Elsevier, 2020)
    Purpose: To describe results of the Amyloid, Tau, Neurodegeneration (ATN) research framework classification in the Argentine-Alzheimer’s Disease Neuroimaging Initiative (arg-ADNI) cohort. Methods: Twenty-three patients ...
  • Acute amnestic syndromes 
    Alessandro, Lucas; Ricciardi, Mario Emiliano; Chaves, Hernán; Allegri, Ricardo Francisco (Elsevier, 2020-03-18)
    Acute amnestic syndromes are usually rare clinical events occurring in emergency situations. Etiological diagnosis can be challenging and underlying causes diverse. They can be transient and totally reversible, or accompanied ...
  • Disease activity impacts disability progression in primary progressive multiple sclerosis 
    Marrodán, Mariano; Bensi, Catalina; Pappolla, Agustín; Rojas, Juan Ignacio; Gaitán, María Inés; Ysrraelit, María Célica; Negrotto, Laura; Fiol, Marcela Paula; Patrucco, Liliana; Cristiano, Edgardo; Farez, Mauricio Franco; Correale, Jorge (Elsevier, 2019-12-14)
    Background Although solid information on the natural history of primary progressive multiple sclerosis (PPMS) is available, evidence regarding impact of disease activity on PPMS progression remains controversial. Objective To ...
  • A novel mutation in PSEN1 (p.T119I) in an Argentine family with early- and late-onset Alzheimer's disease 
    Itzcovich, Tatiana; Chrem Méndez, Patricio Alexis; Vázquez, Silvia; Barbieri-Kennedy, Micaela; Niikado, Matías; Martinetto, Horacio; Allegri, Ricardo Francisco; Sevlever, Gustavo Emilio; Surace, Ezequiel Ignacio (Elsevier, 2020-01)
    Mutations inPSEN1are the most common cause of early-onset Alzheimer’s disease (AD). In this article,we present an Argentine family with autosomal dominant early- and late-onset AD. The proband and 6family members were ...
  • Nosology and Phenomenology of Psychosis in Movement Disorders 
    Rossi, Malco Damián; Farcy, Nicole; Starkstein, Sergio E.; Merello, Marcelo (Wiley, 2020-01-07)
    Background Psychotic symptoms such as delusions and hallucinations are part of the clinical picture of several conditions presenting movement disorders. Phenomenology and epidemiology of psychosis in Parkinson's disease ...
  • Driving and Alzheimer’s disease: A neuropsychological screening battery for the elderly 
    Crivelli, Lucía; Russo, María Julieta; Farez, Mauricio Franco; Bonetto, Mariana; Prado, Cecilia; Calandri, Ismael Luis; Campos, Jorge; Cohen, Gabriela; Chrem Méndez, Patricio Alexis; Sabe, Liliana Raquel; Allegri, Ricardo Francisco (Associação Neurologia Cognitiva e do Comportamento, 2019-07-01)
    As life expectancy increases, there is a marked increase in the elderly population eager to continue driving. A large proportion of these elderly drive safely, however, patients with mild dementia are high-risk drivers. ...
  • Diagnosis of Rapidly Progressive Dementia in a Referral Center in Argentina 
    Acosta, Julián Nicolás; Ricciardi, Mario Emiliano; Alessandro, Lucas; Carnevale, Martín Diego; Farez, Mauricio Franco; Nagel, Vanesa; Allegri, Ricardo Francisco; Varela, Francisco José (Lippincott Williams & Wilkins, 2020-01-01)
    INTRODUCTION: Rapidly progressive dementia (RPD) is a broadly defined clinical syndrome. Our aim was to describe clinical and ancillary study findings in patients with RPD and evaluate their diagnostic performance for the ...

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