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Life events and the onset of motor symptoms in Parkinson's disease

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dc.contributor.author Páez Maggio, Mauricio
dc.contributor.author Rossi, Malco Damián
dc.contributor.author Martinez, V.
dc.contributor.author Wainberg, Florencia N.
dc.contributor.author Merello, Marcelo
dc.date.accessioned 2023-08-30T17:37:55Z
dc.date.available 2023-08-30T17:37:55Z
dc.date.issued 2023-01-11
dc.identifier.citation Páez Maggio, M., Rossi, MD.., Martinez, V., Wainberg, F., Merello, M., 2023. Life events and the onset of motor symptoms in Parkinson’s disease. Parkinsonism Relat Disord 107, 105283. https://doi.org/10.1016/j.parkreldis.2023.105283 es_ES
dc.identifier.uri https://doi.org/10.1016/j.parkreldis.2023.105283
dc.identifier.uri https://repositorio.fleni.org.ar/xmlui/handle/123456789/818
dc.description.abstract Background: Whether there may be any relationship between stressful or traumatic life events (LE) and the subsequent motor symptoms onset in Parkinson's disease (PD) is still controversial. Objectives: To explore whether a subjectively perceived as stressful or traumatic LE were more frequently present in a group of recent motor onset parkinsonian patients (Recent Onset Parkinsonism - ROP) compared with healthy controls (HC) and a group of patients already diagnosed as PD. Methods: A consecutive series of 139 ROP patients, 138 matched PD patients and 138 HC were pooled through a validated LE exposure questionnaire evaluating the number of patients affected by LE and the amount of LE per group occurred in the last year, segregating by subjective severity in total and severe LE. Results: There was no significant difference in the percentage of patients affected by total (p = 0.134) nor by severe (p = 0.133) LE within the 3 groups. No significant difference was observed in the number of total LE between ROP and HC (p = 0.063), ROP and PD (p = 0.688), nor in severe LE (ROP vs. HC, p = 0.637. ROP vs. PD, p = 0.500). Conclusions: During the year of parkinsonian motor symptoms onset, the number of ROP patients exposed to total or severe LE or the amount of total or severe LE suffered by ROP were not significantly different to the group of PD patients or HC. A casual relationship between LE and the onset of motor symptoms in parkinsonian patients may be suggested. es_ES
dc.language.iso eng es_ES
dc.publisher Elsevier es_ES
dc.subject Parkinson Disease es_ES
dc.subject Enfermedad de Parkinson es_ES
dc.subject Psychological Trauma es_ES
dc.subject Trauma Psicológico es_ES
dc.title Life events and the onset of motor symptoms in Parkinson's disease es_ES
dc.type info:eu-repo/semantics/article es_ES
dc.description.fil Fil: Paez Maggio, Mauricio. Fleni. Departamento de Neurología. Servicio de Movimientos Anormales; Argentina.
dc.description.fil Fil: Rossi, Malco Damián. Fleni. Departamento de Neurología. Servicio de Movimientos Anormales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.
dc.description.fil Fil: Martinez, V. Fleni. Departamento de Neurología. Servicio de Movimientos Anormales; Argentina.
dc.description.fil Fil: Wainberg, Florencia N. Fleni. Departamento de Neurología. Servicio de Movimientos Anormales; Argentina.
dc.description.fil Fil: Merello, Marcelo. Fleni. Departamento de Neurología. Servicio de Movimientos Anormales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.
dc.relation.ispartofVOLUME 107
dc.relation.ispartofCOUNTRY Reino Unido
dc.relation.ispartofCITY Oxford
dc.relation.ispartofTITLE Parkinsonism & related disorders
dc.relation.ispartofISSN 1873-5126
dc.type.snrd info:ar-repo/semantics/artículo es_ES


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