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Clinical correlates of fear of falling in progressive supranuclear palsy and multiple system atrophy

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dc.contributor.author Martínez Villota, Viviana Alexandra
dc.contributor.author Terroba Chambi, Cinthia
dc.contributor.author Castillo Torres, Sergio Andrés
dc.contributor.author Rossi, Malco Damián
dc.contributor.author Merello, Marcelo
dc.date.accessioned 2024-02-15T12:58:56Z
dc.date.available 2024-02-15T12:58:56Z
dc.date.issued 2023-05-14
dc.identifier.citation Martínez -Villota VA, Terroba Chambi C, Castillo Torres SA, Rossi MD, Merello M. Clinical correlates of fear of falling in progressive supranuclear palsy and multiple system atrophy. Eur J Neurol. agosto de 2023;30(8):2261-6. es_ES
dc.identifier.uri https://doi.org/10.1111/ene.15864
dc.identifier.uri https://repositorio.fleni.org.ar/xmlui/handle/123456789/982
dc.description.abstract Background and purpose: Clinical correlates of fear of falling (FoF) are scarcely studied in patients with progressive supranuclear palsy (PSP) and multiple system atrophy (MSA). This study was undertaken to evaluate the clinical correlates of FoF in PSP and MSA. Methods: This cross-sectional study features motor, cognitive, and psychiatric assessment and longitudinal evaluation of falls and FoF at 6-month follow-up. Results: Twenty-one patients with PSP-parkinsonism, 22 patients with MSA (13 parkinsonian type and nine cerebellar type), and 22 healthy controls were evaluated; 76.2% of patients with PSP and 86.4% of patients with MSA had FoF regardless of falls. Berg Balance Scale (p < 0.001), Tinetti Mobility Test (p < 0.01), Beck Anxiety Inventory (p = 0.001), and Beck Depression Inventory-II (p = 0.01) correlated with FoF in patients with PSP and MSA, whereas Timed Up and Go test (p = 0.01) and Starkstein Apathy Scale correlated only in MSA (p = 0.04). Conclusions: Mobility, balance, and gait performance as well as anxiety and depression in PSP and MSA, and apathy in MSA, were determinants of FoF. These findings underline the importance of a multidisciplinary approach to FoF in neurodegenerative atypical parkinsonism. es_ES
dc.language.iso eng es_ES
dc.publisher Wiley es_ES
dc.subject Fear es_ES
dc.subject Miedo es_ES
dc.subject Multiple System Atrophy es_ES
dc.subject Atrofia de Múltiples Sistemas es_ES
dc.subject Parkinsonian Disorders es_ES
dc.subject Trastornos Parkinsonianos es_ES
dc.subject Postural Balance es_ES
dc.subject Equilibrio Postural es_ES
dc.subject Supranuclear Palsy, Progressive es_ES
dc.subject Parálisis Supranuclear Progresiva es_ES
dc.title Clinical correlates of fear of falling in progressive supranuclear palsy and multiple system atrophy es_ES
dc.type info:eu-repo/semantics/article es_ES
dc.description.fil Fil: Martínez Villota, Viviana Alexandra. Fleni. Departamento de Neurología. Servicio de Movimientos Anormales; Argentina.
dc.description.fil Fil: Terroba Chambi, Cinthia. Fleni. Departamento de Neurología. Servicio de Movimientos Anormales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.
dc.description.fil Fil: Castillo Torres, Sergio Andrés. Fleni. Departamento de Neurología. Servicio de Movimientos Anormales; Argentina.
dc.description.fil Fil: Rossi, Malco Damián. Fleni. Departamento de Neurología. Servicio de Movimientos Anormales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.
dc.description.fil Fil: Merello, Marcelo. Fleni. Departamento de Neurología. Servicio de Movimientos Anormales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Pontificia Universidad Católica Argentina; Argentina.
dc.relation.ispartofVOLUME 30
dc.relation.ispartofNUMBER 8
dc.relation.ispartofPAGINATION 2261-2266
dc.relation.ispartofCOUNTRY Reino Unido
dc.relation.ispartofCITY Oxford
dc.relation.ispartofTITLE European journal of neurology
dc.relation.ispartofISSN 1468-1331
dc.type.snrd info:ar-repo/semantics/artículo es_ES


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