Repositorio Institucional FLENI: Recent submissions

  • Human MAIT Cell Response Shows Subset Diversity in Multiple Sclerosis (P2.2-089) 
    Correale, Jorge; Carnero Contentti, Edgar; Farez, Mauricio Franco (AAN, 2019-04-16)
    Objective: To investigate cytotoxic activity heterogeneity in MAIT cell populations from MS patients Background: MAIT cells are a subset of innate T lymphocytes characterized by expression of an invariant TCR α-chain ...
  • Predictors of Recurrent Ischemic Stroke in Patients with Embolic Strokes of Undetermined Source and Effects of Rivaroxaban Versus Aspirin According to Risk Status: The NAVIGATE ESUS Trial 
    Hart, Robert G.; Veltkamp, Roland C.; Sheridan, Patrick; Sharma, Mukul; Kasner, Scott E.; Bangdiwala, Shrikant I.; Ntaios, George; Shoamanesh, Ashkan; Ameriso, Sebastián Francisco; Toni, Danilo; Czlonkowska, Anna; Lindgren, Arne; Hankey, Graeme J.; Perera, Kanjana S.; Shuaib, Ashfaq; Coutts, Shelagh B.; Gagliardi, Rubens J.; Berkowitz, Scott D.; Mundl, Hardi; NAVIGATE ESUS Investigators (Elsevier, 2019-05-31)
    Background: Embolic stroke of undetermined source (ESUS) identifies patients with cryptogenic ischemic stroke presumed due to embolism from several unidentified sources. Among patients with recent ESUS, we sought to determine ...
  • Vasculitic Peripheral Neuropathy, differences between Systemic and Non-Systemic etiologies. (P2.4-008) 
    Castiglione, Juan Ignacio; Marrodán, Mariano; Taratuto, Ana Lía; Alessandro, Lucas; Brand, Patricio; Barroso, Fabio Adrián (AAN, 2019-04-16)
    Objective: The objective of this study is to differentiate the clinical presentation, complementary studies and evolution between the Systemic Vasculitis (SV) vs Non-Systemic Vasculitic Neuropathy (NSVN) attended in our ...
  • Long‐term mortality, disability and stroke recurrence in patients with basilar artery occlusion 
    Hawkes, Maximiliano Alberto; Blaginykh, Elena; Ruff, Michael W.; Burrus, Tamika; Wijdicks, Eelco F.M.; Rabinstein, Alejandro A. (Wiley, 2020-03-00)
    Background and purpose: The long-term outcomes and stroke recurrence after basilar artery occlusion (BAO) are largely unknown. We aimed to assess these variables in a comparatively large series of consecutive patients. Methods: ...
  • Comment on: The Geographic Diversity of Spinocerebellar Ataxias (SCAs) in the Americas 
    Guarnaschelli, Marlen; Rossi, Malco Damián; Zajd, Ana; Igarreta, Pilar (Wiley, 2020-01-25)
    Resumen no disponible
  • Glioma del nervio óptico en paciente adulto con presentación hemorrágica tratado mediante abordaje endoscópico transesfenoidal extendido 
    Rabadán, Alejandra T.; Hernández, Diego; Varela, Analía; Diez, Blanca; Rubianes, Javier (Asociación Argentina de Neurocirugía, 2020)
    The optic nerve glioma is a very uncommon entity in adult patients, with little information about its natural history and therapeutical management. We report the case of a 27-year-old patient with acute involvement of the ...
  • A novel mutation in PSEN1 (p.Arg41Ser) in an Argentinian woman with early onset Parkinsonism 
    Gatto, Emilia M.; Rojas, Galeno J.; Nemirovsky, Sergio I.; Da Prat, Gustavo; Persi, Gabriel; Cesarini, Martin; Etcheverry, Jose L.; Gonzalez Rojas, Natalia; Parisi, Virginia; Cordoba, Marta; Sevlever, Gustavo Emilio; Allegri, Ricardo Francisco; Turjanski, Adrian G. (Elsevier, 2020-08)
    Introduction: Mutations in presenilin-1 (PSEN1) account for the majority of cases of familial autosomal dominant early-onset Alzheimer's disease (AD) as well as in sporadic forms. Atypical presentations are reported including ...
  • Priorities to reduce the burden of stroke in Latin American countries 
    Ouriques Martins, Sheila C.; Sacks, Claudio; Hacke, Werner; Brainin, Michael; de Assis Figueiredo, Francisco; Marques Pontes-Neto, Octávio; Lavados, Pablo M.; Marinho, Maria F.; Hoppe Wiegering, Arnold; Vaca McGhie, Diana; Cruz-Flores, Salvador; Ameriso, Sebastián Francisco; Camargo Villareal, Walter M.; Durán, Juan Carlos; Fogolin Passos, José E.; Gomes Nogueira, Raul; Freitas de Carvalho, João J.; Sampaio Silva, Gisele; Cabral Moro, Carla H.; Oliveira-Filho, Jamary (Lancet Pub. Group, 2019-04-24)
    The large and increasing burden of stroke in Latin American countries, and the need to meet the UN and WHO requirements for reducing the burden from non-communicable disorders (including stroke), brought together stroke ...
  • Seizures as an early symptom of autosomal dominant Alzheimer's disease 
    Vöglein, Jonathan; Noachtar, Soheyl; McDade, Eric; Quaid, Kimberly A.; Salloway, Stephen; Ghetti, Bernardino; Noble, James M.; Berman, Sarah B.; Chhatwal, Jasmeer P.; Mori, Hiroshi; Fox, Nick C.; Allegri, Ricardo Francisco; Masters, Colin L.; Buckles, Virginia; Ringman, John M.; Rossor, Martin N.; Schofield, Peter R.; Sperling, Reisa; Jucker, Mathias; Dominantly Inherited Alzheimer Network (Elsevier, 2018-12-05)
    Our objective was to assess the reported history of seizures in cognitively asymptomatic mutation carriers for autosomal dominant Alzheimer's disease (ADAD) and the predictive value of seizures for mutation carrier status ...
  • Branch atheromatous disease diagnosed as embolic stroke of undetermined source: A sub-analysis of NAVIGATE ESUS 
    Uchiyama, Shinichiro; Toyoda, Kazunori; Kitagawa, Kazuo; Okada, Yasushi; Ameriso, Sebastián Francisco; Mundl, Hardi; Berkowitz, Scott D.; Yamada, Takashi; Liu, Yan Yun; Hart, Robert G.; NAVIGATE ESUS Investigators (Sage, 2019-05-17)
    Background: Branch atheromatous disease (BAD) is distinctive from large and small arterial diseases, which is single subcortical infarction larger than lacunar stroke in the territories of deep perforators without relevant ...
  • SWAN-Venule: An Optimized MRI Technique to Detect the Central Vein Sign in MS Plaques 
    Gaitán, María Inés; Yáñez, Paulina; Paday Formenti, María Emilia; Calandri, Ismael Luis; Figueiredo, E.; Sati, P.; Correale, Jorge (Williams & Wilkins, 2020-03)
    Background and purpose: Multiple sclerosis lesions develop around small veins that are radiologically described as the so-called central vein sign. With 7T MR imaging and magnetic susceptibility-based sequences, the central ...
  • Management of Advanced Therapies in Parkinson’s Disease Patients in Times of Humanitarian Crisis: The COVID-19 Experience 
    Fasano, Alfonso; Antonini, Angelo; Katzenschlager, Regina; Krack, Paul; Odin, Per; Evans, Andrew H.; Foltynie, Thomas; Volkmann, Jens; Merello, Marcelo (Wiley, 2020-05-04)
    Background: Although the COVID-19 pandemic is affecting a relatively small proportion of the global population, its effects have already reached everyone. The pandemic has the potential to differentially disadvantage ...
  • Consenso sobre el uso de anticuerpos monoclonales en la migraña en Argentina 
    Doctorovich, Eduardo D.; Martín-Bertuzzi, Fiorella; Goicochea, María Teresa; Miranda, Silvina; Figuerola, María L.; Schubaroff, Pablo A.; Buonanotte, Federico; Rocchi, Viviana; Rua, Isabel; Bruera, Osvaldo; Giglio, Jorge; De Paz, José J.; Pelli-Noble, Raúl; Arago, Laura; Burgos, Marcos; Ayala, Leonardo S.; Davidow, Laura; Bonamico, Lucas (Viguera Editores S.L.U., 2020-02-16)
    Introducción. La migraña es un trastorno muy prevalente que se estima que afecta a alrededor del 15% de los sujetos adultos. Durante los últimos años, se ha evaluado la eficacia y la seguridad de los anticuerpos monoclonales ...
  • Tubular resection of a deep-seated motor cortex lesion: an illustrative clinical case 
    Revuelta Barbero, Juan M.; Yanez-Siller, Juan C.; Villalonga, Juan Francisco; Prevedello, Daniel M. (Minerva Medica, 2018-03-26)
    Resumen no disponible
  • Spike-and-wave epileptiform discharge pattern detection based on Kendall's Tau-b coefficient 
    Quintero Rincón, Antonio; Carenzo, Catalina; Ems, Joaquín; Hirschson, Lourdes; Muro, Valeria L.; D'Giano, Carlos ("Iuliu Haţieganu" Publishing House, 2019-03-30)
    Epilepsy is an important public health issue. An appropriate epileptiform discharge pattern detection of this neurological disease is a typical problem in biomedical engineering. In this paper, a new method is proposed for ...
  • A worldwide perspective of sepsis epidemiology and survival according to age: Observational data from the ICON audit 
    Kotfis, Katarzyna; Wittebole, Xavier; Jaschinski, Ulrich; Solé-Violán, Jordi; Kashyap, Rahul; Leone, Marc; Nanchal, Rahul; Fontes, Luis E.; Sakr, Yasser; Vincent, Jean-Louis; ICON Investigators (Elsevier, 2019-02-13)
    Purpose: To investigate age-related differences in outcomes of critically ill patients with sepsis around the world. Methods: We performed a secondary analysis of data from the prospective ICON audit, in which all adult ...
  • The role of infections in multiple sclerosis 
    Marrodán, Mariano; Alessandro, Lucas; Farez, Mauricio Franco; Correale, Jorge (Sage, 2019-01-14)
    Several lines of evidence suggest that multiple sclerosis (MS), like other autoimmune diseases, may be triggered by microbial infections. Pathogens associated with development or exacerbation of MS include bacteria, such ...
  • Estudio epidemiológico de sepsis grave pediátrica en la República Argentina 
    Jabornisky, Roberto; Sáenz, Silvia S.; Capocasa, Patricia; Jaen, Roxana; Moreno, Rodolfo P.; Landry, Luis; Rufach, Daniel; Santos, Silvia N.; Berrueta, Mabel; Carcillo, Joseph; Vassallo, Juan Carlos; Grupo de Investigación Clínica y Epidemiológica en Terapia Intensiva Pediátrica de la Sociedad Argentina de Pediatría (Sociedad Argentina de Pediatría, 2019-06)
    Introduction: Severe sepsis (SS) is one of the leading causes of pediatric mortality in Argentina. The objective was to describe the epidemiological characteristics and to analyze risk factors associated with mortality ...
  • Stroke Epidemiology in Argentina. Design of a Population-Based Study in General Villegas (EstEPA) 
    Pujol Lereis, Virginia Andrea; Melcon, Mario O.; Hawkes, Maximiliano Alberto; Gómez Schneider, Maia Macarena; Dossi, Daiana Elizabeth; Alet, Matías Javier; Povedano, Guillermo Pablo; Gonzalez, Claudio D.; Ameriso, Sebastián Francisco (Elsevier, 2018-10-04)
    Background: Epidemiological data on stroke is scarce in Latin America. Estudio Epidemiológico Poblacional sobre Accidente Cerebrovascular (EstEPA) is a population-based program planned to assess prevalence, incidence, ...
  • Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease 
    Preische, Oliver; Schultz, Stephanie A.; Apel, Anja; Kuhle, Jens; Kaeser, Stephan A.; Barro, Christian; Gräber, Susanne; Kuder-Buletta, Elke; LaFougere, Christian; Laske, Christoph; Vöglein, Jonathan; Levin, Johannes; Masters, Colin L.; Martins, Ralph N.; Schofield, Peter R.; Rossor, Martin N.; Dominantly Inherited Alzheimer Network (Nature Publishing Group, 2019-01-21)
    Neurofilament light chain (NfL) is a promising fluid biomarker of disease progression for various cerebral proteopathies. Here we leverage the unique characteristics of the Dominantly Inherited Alzheimer Network and ...

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