Repositorio Institucional FLENI: Envíos recientes

  • Petroclival Meningiomas: Experience in Argentinian Center 
    Cervio, Andrés Eduardo; Ruella, Mauro; Domecq, Lucila; Fraire, Jazmín Azul; Marengo, Ricardo; Mormandi, Rubén (Thieme, 2025-02-07)
    Introduction: Petroclival meningiomas are challenging tumors located in a critical region at the skull base. These tumors often present with specific clinical manifestations due to their proximity to vital structures such ...
  • “Skull Base Chondrosarcoma” Analyzing a Rare Pathology 
    Cervio, Andrés Eduardo; Ruella, Mauro; Fraire, Jazmín Azul; Domecq, Lucila; Mormandi, Rubén; Marcó del Pont, Francisco; Marengo, Ricardo (Thieme, 2025-02-07)
    Introduction: Chondrosarcomas are malignant tumors that develop from cells derived from chondrocytes. They constitute ~20% of cancers of the skeletal system and affect people between 40 and 70 years old. Only 2% are located ...
  • Frailty and Implications for Multiple Sclerosis Management 
    Correale, Jorge (American Medical Association, 2025-03-03)
    This Viewpoint discusses the unique needs of patients with multiple sclerosis and frailty and describes the gaps that should be addressed in frailty measurement and clinical management.
  • Next generation brain health: transforming global research and public health to promote prevention of dementia and reduce its risk in young adult populations 
    Farina, Francesca R.; Bridgeman, Katie; Gregory, Sarah; Crivelli, Lucía; Foote, Isabelle F.; Jutila, Otto-Emil I.; Kucikova, Ludmila; Mariano, Luciano I.; Nguyen, Kim-Huong; Thayanandan, Tony; Akindejoye, Funmi; Butler, Joe; Calandri, Ismael Luis; Čepukaitytė, Giedrė; Chiesa, Scott T.; Dawson, Walter D.; Deckers, Kay; De la Cruz-Góngora, Vanessa; Dounavi, Maria-Eleni; Govia, Ishtar (Elsevier, 2024-12-20)
    fforts to prevent dementia can benefit from precision interventions delivered to the right population at the right time; that is, when the potential to reduce risk is the highest. Young adults (aged 18-39 years) are a ...
  • Emerging immune tolerance therapies for neuromyelitis optica spectrum disorder 
    Carnero Contentti, Edgar; Correale, Jorge (Taylor & Francis, 2025-02-23)
    Resumen no disponible
  • Quality of care delivery in patients with acute heart failure: insights from the international REPORT-HF registry 
    Tay, Wan Ting; Katherine, Teng Tiew-Hwa; Ouwerkerk, Wouter; Angermann, Christiane E.; Dickstein, Kenneth; Cleland, John G. F.; Dahlstrom, Ulf; Ertl, Georg; Hassanein, Mahmoud; Perrone, Sergio Víctor; Ghadanfar, Mathieu; Schweizer, Anja; Obergfell, Achim; Collins, Sean P.; Filippatos, Gerasimos; Lam, Carolyn S. P.; Tromp, Jasper (Elsevier, 2025-01-10)
    Background: Heart Failure (HF) quality of care (QoC) is associated with clinical outcomes. Therefore, we investigated differences in HF QoC across worldwide regions (with differing national income) and the association of ...
  • National Multicenter Study on the Prevalence of Carbapenemase-Producing Enterobacteriaceae in the Post-COVID-19 Era in Argentina: The RECAPT-AR Study 
    Genero, Fabiana; Gaudenzi, Florencia; Echegorry, Mariano; Marchetti, Paulina; Sanchez, Cristian; Olivieri, Laura; Faccone, Diego; Martino, Florencia; Sarkis Badola, Tomas; Ceriana, Paola; Rapoport, Melina; Lucero, Celeste; Albornoz, Ezequiel; Recapt-Ar Group; Corso, Alejandra; Pastera, Fernando (MDPI, 2024-11-27)
    The COVID-19 pandemic has exacerbated the global antimicrobial resistance (AMR) crisis. Consequently, it is more urgent than ever to prioritize AMR containment and support countries in improving the detection, characterization, ...
  • Cost evaluation of acute ischemic stroke in Latin America: a multicentric study 
    Dittrich, Luiza Borba; da Silva Etges, Ana Paula Beck; Siqueira de Souza, Joana; Zago Marcolino, Miriam Allein; Rocha, Eva; Amaya, Pablo; Barboza, Miguel A.; Saavedra, Andrés Gaye; Pérez Hornos, Gonzalo; Abanto, Carlos; Castillo-Soto, Ana Lucía; Llanos-Leyton, Natalia; Pujol Lereis, Virginia Andrea; Rodriguez Pérez, María Soledad; Alet, Matías Javier; Navia, Victor; Lopez, Solange; Arauz, Antonio; Serrano, Fabiola; Chwal, Bruna; Carbonera, Leonardo Augusto; Gomes Nogueira, Raul; Saposnik, Gustavo; Polanczyk, Carisi Anne; Ouriques Martins, Sheila Cristina; de Souza, Ana Cláudia (Elsevier, 2024-12-06)
    Background: Current literature highlights a gap in precise stroke cost data for Latin America. This study measures the real costs associated with acute ischemic stroke care in Latin America using Time-Driven Activity-Based ...
  • Risk factors and baseline cognition. Preliminary results from the LatAm-FINGERS cohort 
    Corvalán, Nicolás; Keller, Greta; Surace, Ezequiel Ignacio; Calandri, Ismael Luis; Dozzi Brucki, Sonia María; Salinas Contreras, Rosa María; Suemoto, Claudia Kimie; Velilla, Lina M.; Sanches Yassuda, Monica; Allegri, Ricardo Francisco; Caramelli, Paulo; Lopera, Francisco; Nitrini, Ricardo; Sosa, Ana Luisa; Sevlever, Gustavo Emilio; Crivelli, Lucía; LatAm-FINGERS Consortium (Wiley, 2024)
    Background LatAm-FINGERS - the first non-pharmacological multicenter randomized clinical trial in Latin America - is a valuable opportunity to study lifestyle in a heterogeneous and multiethnic population exposed to a ...
  • Live-attenuated vaccines for multiple sclerosis patients living in regions with endemic infections: A complex decision 
    Correale, Jorge; Marrodan, Mariano (Sage, 2024-12-18)
    Live-attenuated vaccines provide robust immunity against diseases like tuberculosis, measles, mumps, rubella, polio, yellow fever, dengue, typhoid fever, and varicella, with just one or a few doses. However, concerns arise ...
  • Chapter 10 - Autoimmune Astrocytopathy 
    Correale, Jorge (Springer Nature, 2024)
    Astrocytes constitute the most abundant type of glial cells in the central nervous system (CNS) and display significant heterogeneity. Astrocytes actively engage in various metabolic processes and are active contributors ...
  • Case report: A 50 year-old Down syndrome man exhibiting noAlzheimer’s disease biomarker profile nor cognitiveimpairment. Experience from the Argentine Initiative for theStudy of Down syndrome and Alzheimer’s 
    Clas, Giulia Solange; Pertierr, Lucía; Helou, María Belén; Tapajóz Pereira de Sampaio, Fernanda, Fernanda; Magrath Guimet, Nahuel; Allegri, Ricardo Francisco; Marazita, Mariela; Romorini, Leonardo; Surace, Ezequiel Ignacio (Wiley, 2024)
    Background: Down Syndrome (DS) is the most common genetic form of intellectualdisability. In recent years, there has been a significant increase in the life expectancyof individuals with DS, currently reaching the age of ...
  • Additional Cladribine tablets treatment courses in multiple sclerosis patients. A retrospective observational study in Latin American countries 
    Silva, Berenice Anabel; Ysrraelit, María Célica; Zanga, Gisela; Segamarchi, María Constanza; Cragnolini, Carolina; Galleguillos, Lorna; Halfon, Mario Javier; Miguez, Jimena; Parada Marcilla, Marcela; Pereyra, Adriana; Silva, Emanuel; Vrech, Carlos; D'Eramo, Mariana; Negrotto, Laura (Elsevier, 2025-01-14)
    The use of additional cladribine tablets treatment courses is becoming an option in patients with multiple sclerosis (MS) showing disease activity after treatment initiation. Despite the availability over the past year of ...
  • Classification and Genotype-Phenotype Relationships of GBA1 Variants: MDSGene Systematic Review 
    Rossi, Malco Damián; Schaake, Susen; Usnich, Tatiana; Boehm, Josephine; Steffen, Nina; Schell, Nathalie; Krüger, Clara; Gül-Demirkale, Tuğçe; Bahr, Natascha; Kleinz, Teresa; Madoev, Harutyun; Laabs, Björn-Hergen; Gan-Or, Ziv; Alcalay, Roy N.; Lohmann, Katja; Klein, Christine (Wiley, 2025-02-10)
    Depending on zygosity and the specific change, different variants in the GBA1 gene can cause Parkinson's disease (PD, PARK-GBA1) with reduced penetrance, act as genetic risk factors for PD or parkinsonism, and/or lead to ...
  • Association between the balance recovery and the independence after a severe stroke 
    Gath, Christian Federico; Lado, Vanina; Gianella, Matías Gabriel; Bonamico, Lucas; Russo, María Julieta (Taylor & Francis, 2025-02-27)
    Objectives: Research is lacking on the recovery of subjects who have suffered a stroke and have severely impaired balance in the subacute stage. This study aims to analyze the association between balance recovery during ...
  • Vertical Video-based Gait Analysis for Assessment of Transverse Plane Motion: Reliability and Validity in a Neuromuscular Population 
    Olleac, Ramiro; Centeno, Bernardo; Duffy, Clara; Nuñez, Marcos; Marcos José, Crespo; Barrios, Lucas M.; Davids, Jon R.; Kulkarni, Vedant A. (Lippincott Williams & Wilkins, 2025-02-14)
    Background: In the absence of 3-dimensional gait analysis (3DGA), assessment of transverse plane motion of the lower extremity from sagittal and coronal video has a high degree of error. We propose a standardized method ...
  • Performance of treatment response scoring systems among patients with multiple sclerosis treated with high-efficacy therapies 
    Marrodán, Mariano; Sao Avilés, Augusto; Río, Jordi; Cobo-Calvo, Álvaro; Fernández, Victoria; Pappolla, Agustin; Castilló, Joaquín; Vidal-Jordana, Ángela; Arrambide, Georgina; Tur, Carmen; Rodríguez-Acevedo, Breogán; Zabalza, Ana; Mongay-Ochoa, Neus; Vilaseca, Andreu; Rodriguez, Marta; Galán, Ingrid; Comabella, Manuel; Sastre-Garriga, Jaume; Tintoré, Mar; Auger, Cristina (Sage, 2025-02-10)
    Background: Predicting treatment response and disease progression in multiple sclerosis (MS) is challenging. Treatment Response Scoring Systems (TRSS) are potentially useful, but their utility in patients receiving ...
  • The landscape of autosomal-dominant Alzheimer's disease: global distribution and age of onset. 
    Liu, Haiyan; Marsh, Thomas W.; Shi, Xinyu; Renton, Alan E.; Bowling, Kevin M.; Ziegemeier, Ellen; Wang, Guoqiao; Cao, Yuchen; Aristel, Alisha; Li, Jessie; Dickson, Alexa; Perrin, Richard J.; Goate, Alison M.; Fernández, Victoria; Day, Gregory S.; Doering, Michelle; Daniels, Alisha; Supnet-Bell, Charlene; Allegri, Ricardo Francisco; Chrem Méndez, Patricio Alexis (Oxford University Press, 2025-02-04)
    We present a comprehensive global analysis of genetic variants associated with autosomal-dominant Alzheimer's disease (ADAD). A total of 550 variants in the APP, PSEN1, and PSEN2 genes were identified, of which 279 were ...
  • Safety and efficacy of purely endoscopic microvascular decompression for trigeminal neuralgia: systematic review and single arm meta-analysis 
    Gago, Guilherme; Ruella, Mauro; Strangio, Antonio; de Lima Gibbon, Frederico; Cotrim Gomes, Fernando; Lindner, Rafaela J.; Gomes Paz, Matheus; Champagne, Pierre-Olivier (Springer, 2025-02-07)
    Microscopic microvascular decompression(M-MVD) is considered the gold standard treatment for primary trigeminal neuralgia and presents excellent long-term pain control rates. Despite the effectiveness of M-MVD, the use of ...
  • Exosomal mRNA Signatures as Predictive Biomarkers for Risk and Age of Onset in Alzheimer's Disease 
    Bolívar, Daniel A.; Mosquera Heredia, María I.; Vidal, Oscar M.; Barceló, Ernesto; Allegri, Ricardo Francisco; Morales, Luis C.; Silvera Redondo, Carlos; Arcos Burgos, Mauricio; Garavito Galofre, Pilar; Vélez, Jorge I. (MDPI, 2024-11-15)
    Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive cognitive decline and memory loss. While the precise causes of AD remain unclear, emerging evidence suggests that messenger RNA (mRNA) ...