Repositorio Institucional FLENI: Envíos recientes

  • Generation of a human induced pluripotent stem cell line from a familial Alzheimer's disease PSEN1 T119I patient 
    Isaja, Luciana; Rodríguez Varela, María Soledad; Marazita, Mariela Claudia; Mucci, Sofía; Itzcovich, Tatiana; Chrem Méndez, Patricio Alexis; Niikado, Matías; Ferriol Laffouillere, Sofía Luján; Allegri, Ricardo Francisco; Martinetto, Horacio; Sevlever, Gustavo Emilio; Scassa, María Élida; Surace, Ezequiel Ignacio; Romorini, Leonardo (Elsevier, 2021-04-05)
    Human induced pluripotent stem cells (hiPSC) line FLENIi001-A was reprogrammed from dermal fibroblasts using the lentiviral-hSTEMCCA-loxP vector. Fibroblasts were obtained from a skin biopsy of a 72-year-old Caucasian male ...
  • Global Impact of COVID-19 on Stroke Care and Intravenous Thrombolysis 
    Nogueira, Raul G.; Qureshi, Muhammad M.; Abdalkader, Mohamad; Ouriques Martins, Sheila C.; Yamagami, Hiroshi; Qiu, Zhongming; Yassin Mansour, Ossama; Sathya, Anvitha; Czlonkowska, Anna; Tsivgoulis, Georgios; Aguiar de Sousa, Diana; Demeestere, Jelle; Mikulik, Robert; Vanacker, Peter; Siegler, James E.; Kõrv, Janika; Biller, Jose; Liang, Conrad W.; Sangha, Navdeep S.; Pujol Lereis, Virginia Andrea (AAN, 2021-03-25)
    Objective: The objectives of this study were to measure the global impact of the pandemic on the volumes for intravenous thrombolysis (IVT), IVT transfers, and stroke hospitalizations over 4 months at the height of the ...
  • Correlation between 99mTc-TRODAT-1 SPECT and 18F-FDOPA PET in patients with Parkinson’s disease: a pilot study 
    Arena, Julieta E.; Urrutia, Leandro; Falasco, Germán; Ponce de León, Magdalena; Vázquez, Silvia; Rossi, Malco Damián; Merello, Marcelo (Colégio Brasileiro de Radiologia e Diagnóstico por Imagem, 2021-03-05)
    Objective: To determine whether technetium-99m-labeled tropane derivative single-photon emission computed tomography (99mTcTRODAT-1 SPECT) provides results comparable to those of the less widely available, less accessible ...
  • Abstract P80: Control of Vascular Risk Factors and Response to Stroke Symptoms During the Most Restrictive Period of the Covid-19 Quarantine. A Survey of Population Behavior in Argentina 
    Rodriguez Pérez, María Soledad; Rosales, Julieta Soledad; Dossi, Daiana Elizabeth; Ameriso, Sebastián Francisco (Lippincott Williams & Wilkins, 2021-03-11)
    Background and objectives: In preparation for the influx of Covid-19 patients and as a contagion prevention strategy, healthcare systems reduced or discontinued provision of ‘‘non-urgent’’ care. This policy could potentially ...
  • Abstract P84: Covid-19 and Stroke in the Latin American Stroke Registry (LASE) 
    Pujol Lereis, Virginia Andrea; Flores, Alan; Arauz-Gongora, Antonio; Abanto Argomedo, Carlos; Amaya, Pablo; Bayona, Hernán; Bonardo, Pablo; Diaz Escobar, Luis; Gomez Schneider, Maia Macarena; Góngora Rivera, Fernando; Lavados, Pablo M.; León, Carolina; Luraschi, Adriana; Márquez Romero, Juan Manuel; Martins, Sheila C.; Navia, Víctor Hugo; Ruiz Franco, Angélica; Vences, Miguel Ángel; Ameriso, Sebastián Francisco; LASE/COVID-19 Collaborators (Lippincott Williams & Wilkins, 2021-03-11)
    Background: Ischemic stroke has been reported to occur in approximately 5% of COVID-19 patients, although some reports are contradictory. Proposed mechanisms of this association are hypercoagulable state, vasculitis and ...
  • Abstract P385: Stroke-Related Hospital Admissions During Covid-19 Pandemic in the Latin American Stroke Registry (LASE) 
    Pujol Lereis, Virginia Andrea; Flores, Alan; Arauz-Gongora, Antonio; Abanto Argomedo, Carlos; Amaya, Pablo; Bayona, Hernán; Bonardo, Pablo; Diaz-Escobar, Luis; Gomez Schneider, Maia Macarena; Góngora Rivera, Fernando; Lavados, Pablo M.; León, Carolina; Luraschi, Adriana; Márquez Romero, Juan Manuel; Martins, Sheila C.; Navia, Víctor Hugo; Ruiz Franco, Angélica; Vences, Miguel Ángel; Ameriso, Sebastián Francisco; LASE/COVID-19 Collaborators (Lippincott Williams & Wilkins, 2021-03-11)
    Background: COVID-19 pandemic has forced important changes in health care worldwide. Stroke care networks have been affected, especially acute admissions and ancillary tests availability. We assessed the impact of the ...
  • COVID-19 Epidemic in Argentina: Worsening of Behavioral Symptoms in Elderly Subjects With Dementia Living in the Community 
    Cohen, Gabriela; Russo, María Julieta; Campos, Jorge; Allegri, Ricardo Francisco (Frontiers Research Foundation, 2020-08-28)
    In Argentina, the quality of care that elderly subjects with dementia living in the community received has been deeply affected by COVID-19 epidemic. Our objective was to study to what extend mandatory quarantine imposed ...
  • Utility of a Screening Test (MoCa) to Predict Amyloid Physiopathology in Mild Cognitive Impairment 
    Clarens, María Florencia; Calandri, Ismael Luis; Helou, María Belén; Martín, María Eugenia; Chrem Méndez, Patricio Alexis; Crivelli, Lucía (Universidad de la Costa, 2020-11-09)
    Introduction: The MoCa (Montreal Cognitive Assessment) Screening test has become relevant in recent years in the screening of patients with Mild Cognitive Impairment (MCI). It is important to seek and study simple and ...
  • Diagnostic accuracy of the UDS 3.0 neuropsychological battery in a cohort with Alzheimer's disease in Colombia 
    Porto, Maria F.; Benitez Agudelo, Juan Camilo; Aguirre Acevedo, Daniel Camilo; Barceló Martínez, Ernesto; Allegri, Ricardo Francisco (Taylor & Francis, 2021-03-24)
    Background: Alzheimer's disease (AD) is a neurodegenerative disease that causes a gradual loss of cognitive functions and limits daily activities performance. Early diagnosis of AD is essential to start timely treatment. ...
  • COVID-19 in multiple sclerosis and neuromyelitis optica spectrum disorder patients in Latin America: COVID-19 in MS and NMOSD patients in LATAM 
    Alonso, Ricardo; Silva, Berenice Anabel; Garcea, Orlando; Correa Díaz, Edgar Patricio; Rodrigues Dos Passos, Giordani; Ramirez Navarro, Deyanira A.; Garcia Valle, Luis A.; Rodriguez Salinas, Luis C.; Negrotto, Laura; Luetic, Geraldine G.; Tkachuk, Verónica A.; Míguez, Jimena S.; Hamuy, Fernando; Goiry, Lorna Galleguillos; Ramírez Sánchez, Nicia E.; Burgos, Marcos; Steinberg, Judith; Balbuena Aguirre, María Eugenia; Monterrey Alvarez, Priscilla; Ysrraelit, María Célica (Elsevier, 2021-03-07)
    Background: There is no data regarding COVID-19 in Multiple Sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) patients in Latin America. Objective: The objective of this study was to describe the clinical ...
  • Iron Metabolism in Oligodendrocytes and Astrocytes, Implications for Myelination and Remyelination 
    Cheli, Veronica Teresita; Correale, Jorge; Paez, Pablo M.; Pasquini, Juana María (Sage, 2020-01)
    Iron is a key nutrient for normal central nervous system (CNS) development and function; thus, iron deficiency as well as iron excess may result in harmful effects in the CNS. Oligodendrocytes and astrocytes are crucial ...
  • A look back into a typical patient with memory complains 
    Chrem Méndez, Patricio Alexis; Vázquez, Silvia (Universidad de la Costa, 2020-12-07)
    The purpose of these images is to extol the biological perspective from the clinical setting perspective of a typical AD case. This participant was profoundly studied and also followed-up for five years in the study ADNI- ...
  • Segregation of functional networks is associated with cognitive resilience in Alzheimer's disease 
    Ewers, Michael; Luan, Ying; Frontzkowski, Lukas; Neitzel, Julia; Rubinski, Anna; Dichgans, Martin; Hassenstab, Jason; Gordon, Brian A.; Chhatwal, Jasmeer P.; Levin, Johannes; Schofield, Peter R.; Benzinger, Tammie L.S.; Morris, John C.; Goate, Alison M.; Karch, Celeste M.; Fagan, Anne M.; McDade, Eric; Allegri, Ricardo Francisco; Berman, Sarah B.; Chui, Helena C. (Oxford, 2021-03-16)
    Cognitive resilience is an important modulating factor of cognitive decline in Alzheimer's disease, but the functional brain mechanisms that support cognitive resilience remain elusive. Given previous findings in normal ...
  • Brain volumes quantification from MRI in healthy controls: Assessing correlation, agreement and robustness of a convolutional neural network-based software against FreeSurfer, CAT12 and FSL 
    Chaves, Hernán; Dorr, Francisco; Costa, Martín Elías; Serra, María Mercedes; Fernández Slezak, Diego; Farez, Mauricio Franco; Sevlever, Gustavo Emilio; Yáñez, Paulina; Cejas, Claudia Patricia (Masson, 2020-10-01)
    Background and purpose: There are instances in which an estimate of the brain volume should be obtained from MRI in clinical practice. Our objective is to calculate cross-sectional robustness of a convolutional neural ...
  • Tratamiento quirúrgico de los cavernomas de tronco cerebral 
    Cervio, Andrés Eduardo; Giovannini, Sebastián Juan María; Nuñez, Maximiliano; Caffaratti, Guido; Grijalba Romero, Miguel; Villamil, Facundo; Mormandi, Rubén (2020)
    Introducción Los cavernomas del tronco cerebral (CTC) son malformaciones vasculares de bajo flujo que pueden detactarse incidentalmente o presentarse con sangrado y déficit neurológico. La resección quirúrgica continúa ...
  • The sellar barrier and intraoperative CSF leak in elderly patients 
    Ries Centeno, Tomás; Villalonga, Juan Francisco; Saenz, Amparo; Marcó Del Pont, Francisco; Cervio, Andrés Eduardo; Campero, Álvaro (Churchill Livingstone (Elsevier), 2020-03)
    Cerebral spinal fluid (CSF) leak is a significant complication in pituitary surgery, increasing both patient morbidity and mortality. In a recent publication, Campero et al. observed worse postoperative prognosis and ...
  • Cytotoxic lesion of the corpus callosum in a patient with aphasic status epilepticus 
    Castiglione, Juan Ignacio; Ricciardi, Mario Emiliano; Bensi, Catalina (Universidad de la Costa, 2020-12-07)
    A 47-year-old man with a history of aphasic seizures presented to the emergency room with a 12-hour global aphasia. Upon admission, brain MRI did not reveal acute lesions, and EEG showed sharp waves in the left frontal-temporal ...
  • Spinal cord and brain MRI should be routinely performed during follow-up in patients with NMOSD - Yes 
    Carnero Contentti, Edgar; Correale, Jorge (Sage, 2021-01)
  • Latin American consensus recommendations for management and treatment of neuromyelitis optica spectrum disorders in clinical practice 
    Carnero Contentti, Edgar; Rojas, Juan Ignacio; Cristiano, Edgardo; Daccach Marques, Vanessa; Flores, José; Lana Peixoto, Marco A.; Navas, Carlos; Papais Alvarenga, Regina; Sato, Douglas K.; Soto de Castillo, Ibis; Correale, Jorge (Elsevier, 2020-10)
    Background: During the last two decades, neuromyelitis optica spectrum disorder (NMOSD) has undergone important changes, with new diagnostic markers and criteria, better recognition of clinical phenotypes, better disease ...
  • Distinct Neural Processing of Acute Stress in Major Depression and Borderline Personality Disorder 
    Villarreal, Mirta Fabiana; Wainsztein, Agustina Edith; Álvarez Mercé, Rocío; Goldberg, Ximena; Castro, Mariana Nair; Brusco, Luis Ignacio; Ladrón de Guevara, María Soledad; Bodurka, Jerzy; Paulus, Martin; Menchón, José Manuel; Soriano-Mas, Carles; Guinjoan, Salvador Martín (Elsevier, 2021-02-26)
    Background: Major depressive disorder (MDD) and borderline personality disorder (BPD) are highly prevalent and often comorbid psychiatric conditions, with abnormal processing of negative affect resulting from psychological ...