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Mortality of neuromyelitis optica spectrum disorder patients in an Argentinean population: A study from the RelevarEM registry

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dc.contributor.author Carnero Contentti, Edgar
dc.contributor.author López, Pablo Adrián
dc.contributor.author Pettinicchi, Juan Pablo
dc.contributor.author Criniti, Juan
dc.contributor.author Pappolla, Agustín
dc.contributor.author Miguez, Jimena
dc.contributor.author Cristiano, Edgardo
dc.contributor.author Patrucco, Liliana
dc.contributor.author Liwacki, Susana
dc.contributor.author Tkachuk, Verónica A.
dc.contributor.author Balbuena Aguirre, María Eugenia
dc.contributor.author Vrech, Carlos
dc.contributor.author Deri, Norma
dc.contributor.author Correale, Jorge
dc.contributor.author Marrodán, Mariano
dc.contributor.author Ysrraelit, María Célica
dc.contributor.author Leguizamon, Felisa
dc.contributor.author Luetic, Geraldine G.
dc.contributor.author Menichini, María Laura
dc.contributor.author Tavolini, Darío
dc.date.accessioned 2024-03-15T15:38:19Z
dc.date.available 2024-03-15T15:38:19Z
dc.date.issued 2023-10-17
dc.identifier.citation Carnero Contentti E, Lopez PA, Pettinicchi JP, Criniti J, Pappolla A, Miguez J, et al. Mortality of neuromyelitis optica spectrum disorder patients in an Argentinean population: A study from the RelevarEM registry. Mult Scler J Exp Transl Clin. 2023;9(4):20552173231205444. es_ES
dc.identifier.issn 2055-2173
dc.identifier.uri https://repositorio.fleni.org.ar/xmlui/handle/123456789/1043
dc.identifier.uri https://doi.org/10.1177/20552173231205444
dc.description.abstract We aimed to evaluate mortality and causes of death among Argentinean neuromyelitis optica spectrum disorder (NMOSD) patients and identify predictors of death. Retrospective study included 158 NMOSD patients and 11 (7%) patients died after 11 years of follow-up for a total exposure time of 53,345 days with an overall incidence density of 2.06 × 10.000 patients/day (95% CI 1.75-2.68). Extensive cervical myelitis with respiratory failure (45%) was the most frequent cause of death. Older age (HR = 2.05, p = 0.002) and higher disability score (HR = 2.30, p < 0.001) at disease onset were independent predictors of death. We found an 11-year mortality rate of 7% in Argentinean NMOSD patients. es_ES
dc.language.iso eng es_ES
dc.publisher Sage es_ES
dc.rights info:eu-repo/semantics/openAccess
dc.subject Latin America es_ES
dc.subject América Latina es_ES
dc.subject Neuromyelitis Optica es_ES
dc.subject Neuromielitis Óptica es_ES
dc.title Mortality of neuromyelitis optica spectrum disorder patients in an Argentinean population: A study from the RelevarEM registry es_ES
dc.type info:eu-repo/semantics/article es_ES
dc.type info:eu-repo/semantics/publishedVersion
dc.description.fil Fil: Correale, Jorge. Fleni. Departamento de Neurología. Servicio de Neuroinmunología y Enfermedades Desmielinizantes; Argentina.
dc.description.fil Fil: Marrodán, Mariano. Fleni. Departamento de Neurología. Servicio de Neuroinmunología y Enfermedades Desmielinizantes; Argentina.
dc.description.fil Fil: Ysrraelit, María Célica. Fleni. Departamento de Neurología. Servicio de Neuroinmunología y Enfermedades Desmielinizantes; Argentina.
dc.relation.ispartofVOLUME 9
dc.relation.ispartofNUMBER 4
dc.relation.ispartofCOUNTRY Estados Unidos
dc.relation.ispartofCITY Thousand Oaks
dc.relation.ispartofTITLE Multiple sclerosis journal - experimental, translational and clinical
dc.relation.ispartofISSN 2055-2173
dc.type.snrd info:ar-repo/semantics/artículo es_ES


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