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Performance on the Latin American version of the Face-Name Associative Memory Exam (LAS-FNAME) distinguishes individuals with Mild Cognitive Impairment from age-matched controls in a sample from Argentina.

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dc.contributor.author Keller, Greta
dc.contributor.author Corvalán, Nicolás
dc.contributor.author Carello, María Agostina
dc.contributor.author Arruabarrena, Micaela María
dc.contributor.author Martínez Canyazo, Carlos
dc.contributor.author De Los Santos, Loana
dc.contributor.author Spehrs, Julieta
dc.contributor.author Vila-Castelar, Clara
dc.contributor.author Allegri, Ricardo Francisco
dc.contributor.author Quiroz, Yakeel T.
dc.contributor.author Crivelli, Lucía
dc.date.accessioned 2024-04-16T11:38:00Z
dc.date.available 2024-04-16T11:38:00Z
dc.date.issued 2024-03-06
dc.identifier.citation Keller G, Corvalan N, Carello MA, Arruabarrena MM, Martínez-Canyazo C, De Los Santos L, Spehrs J, Vila-Castelar C, Allegri RF, Quiroz YT, Crivelli L. Performance on the Latin American version of the Face-Name Associative Memory Exam (LAS-FNAME) distinguishes individuals with Mild Cognitive Impairment from age-matched controls in a sample from Argentina. Appl Neuropsychol Adult. 2024 Mar 6:1-9. doi: 10.1080/23279095.2024.2323627. Epub ahead of print. es_ES
dc.identifier.uri https://doi.org/10.1080/23279095.2024.2323627
dc.identifier.uri https://repositorio.fleni.org.ar/xmlui/handle/123456789/1075
dc.description.abstract Introduction: The Latin American Spanish version of the Face-Name Associative Memory Exam (LAS-FNAME) has shown promise in identifying cognitive changes in those at risk for Alzheimer's disease (AD). However, its applicability for Mild Cognitive Impairment (MCI) detection in the Latin American population remains unexplored. This study aims to analyze the psychometric properties in terms of validity and reliability and diagnostic performance of the LAS-FNAME for the detection of memory disorders in patients with amnestic MCI (aMCI). Materials and methods: The study included 31 participants with aMCI, diagnosed by a neurologist according to Petersen's criteria, and 19 healthy controls. Inclusion criteria for the aMCI group were to be 60 years of age or older, report cognitive complaints, have a memory test score (Craft Story 21) below a -1.5 z-score and have preserved functioning in activities of daily living. Participants completed LAS-FNAME and a comprehensive neuropsychological assessment. Results: LAS-FNAME showed the ability to discriminate against healthy controls from patients with aMCI (AUC= 75) in comparison with a gold-standard memory test (AUC = 69.1). LAS-FNAME also showed evidence of concurrent and divergent validity with a standard memory test (RAVLT) (r = 0.58, p < .001) and with an attention task (Digit Span) (r = -0.37, p = .06). Finally, the reliability index was very high (α = 0.88). Discussion: LAS-FNAME effectively distinguished aMCI patients from healthy controls, suggesting its potential for detecting early cognitive changes in Alzheimer's prodromal stages among Spanish speakers. es_ES
dc.language.iso eng es_ES
dc.publisher Taylor & Francis es_ES
dc.subject Disfunción Cognitiva es_ES
dc.subject Cognitive Dysfunction es_ES
dc.subject Alzheimer Disease es_ES
dc.subject Enfermedad de Alzheimer es_ES
dc.title Performance on the Latin American version of the Face-Name Associative Memory Exam (LAS-FNAME) distinguishes individuals with Mild Cognitive Impairment from age-matched controls in a sample from Argentina. es_ES
dc.type info:eu-repo/semantics/article es_ES
dc.description.fil Fil: Keller, Greta. Fleni. Departamento de Neurología. Servicio de Neurología Cognitiva, Neuropsicología y Neuropsiquiatría; Argentina.
dc.description.fil Fil: Corvalán, Nicolás. Fleni. Departamento de Neurología. Servicio de Neurología Cognitiva, Neuropsicología y Neuropsiquiatría; Argentina.
dc.description.fil Fil: Carello, María Agostina. Fleni. Departamento de Neurología. Servicio de Neurología Cognitiva, Neuropsicología y Neuropsiquiatría; Argentina.
dc.description.fil Fil: Arruabarrena, Micaela María. Fleni. Departamento de Neurología. Servicio de Neurología Cognitiva, Neuropsicología y Neuropsiquiatría; Argentina.
dc.description.fil Fil: Martínez Canyazo, Carlos. Fleni. Departamento de Neurología. Servicio de Neurología Cognitiva, Neuropsicología y Neuropsiquiatría; Argentina.
dc.description.fil Fil: De Los Santos, Loana. Fleni. Departamento de Neurología. Servicio de Neurología Cognitiva, Neuropsicología y Neuropsiquiatría; Argentina.
dc.description.fil Fil: Spehrs, Julieta. Fleni. Departamento de Neurología. Servicio de Neurología Cognitiva, Neuropsicología y Neuropsiquiatría; Argentina.
dc.description.fil Fil: Allegri, Ricardo Francisco. Fleni. Departamento de Neurología. Servicio de Neurología Cognitiva, Neuropsicología y Neuropsiquiatría; Argentina. Fleni. Instituto de Neurociencias FLENI-CONICET; Argentina.
dc.description.fil Fil: Crivelli, Lucía. Fleni. Departamento de Neurología. Servicio de Neurología Cognitiva, Neuropsicología y Neuropsiquiatría; Argentina. Fleni. Instituto de Neurociencias FLENI-CONICET; Argentina.
dc.description.fil Fil: Vila-Castelar, Clara. Harvard Medical School; Estados Unidos.
dc.relation.ispartofCOUNTRY Estados Unidos
dc.relation.ispartofCITY Filadelfia
dc.relation.ispartofISSN 2327-9109
dc.type.snrd info:ar-repo/semantics/artículo es_ES


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