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Survey among experts on the future role of tau-PET in clinical practice and trials

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dc.contributor.author Vermeiren, Marie R.
dc.contributor.author Calandri, Ismael Luis
dc.contributor.author van der Flier, Wiesje M.
dc.contributor.author van de Giessen, Elsmarieke
dc.contributor.author Ossenkoppele, Rik
dc.date.accessioned 2024-12-10T15:45:06Z
dc.date.available 2024-12-10T15:45:06Z
dc.date.issued 2024
dc.identifier.citation Vermeiren MR, Calandri IL, van der Flier WM, van de Giessen E, Ossenkoppele R. Survey among experts on the future role of tau-PET in clinical practice and trials. Alzheimers Dement (Amst). 2024 Nov 22;16(4):e70033. doi: 10.1002/dad2.70033. es_ES
dc.identifier.uri https://doi.org/10.1002/dad2.70033
dc.identifier.uri https://repositorio.fleni.org.ar/xmlui/handle/123456789/1300
dc.description.abstract Background: Recent advancements in Alzheimer's disease (AD) biomarker research and clinical trials prompt reflection on the value and consequently appropriate use of tau positron emission tomography (tau-PET) in the future. Methods: We conducted an online survey among dementia and PET experts worldwide to investigate the anticipated future role of tau-PET in clinical practice and trials. Results: Two hundred sixty-eight dementia experts, comprising 143 clinicians and 121 researchers, covering six continents participated. The vast majority (90%) fostered a positive attitude toward the added value of tau-PET in clinical practice, particularly for staging, diagnosing, monitoring, and prognostication in a cognitively impaired memory clinic population. Experts anticipated an important role for tau-PET for participant selection (76%-100%) and measuring endpoints (75%-97%), in both anti-amyloid and anti-tau drug trials. Discussion: Our global survey study shows that dementia experts envision an important role for tau-PET in the future, both in clinical practice and in drug trials, beyond current guidelines and practices. Highlights: Dementia experts envision an important role for tau-PET in the future.Experts indicate that a tau-PET scan could influence patient management.Experts anticipate the utility of tau-PET for participant selection and endpoints in drug trials.There is a gap between the anticipated usefulness of tau-PET and current clinical practices. es_ES
dc.language.iso eng es_ES
dc.publisher Wiley on behalf of the Alzheimer's Association es_ES
dc.rights info:eu-repo/semantics/openAccess
dc.subject Proteínas tau es_ES
dc.subject tau Proteins es_ES
dc.subject Tomografía de Emisión de Positrones es_ES
dc.subject Positron-Emission Tomography es_ES
dc.subject Alzheimer Disease es_ES
dc.subject Enfermedad de Alzheimer es_ES
dc.title Survey among experts on the future role of tau-PET in clinical practice and trials es_ES
dc.type info:eu-repo/semantics/article es_ES
dc.type info:eu-repo/semantics/publishedVersion
dc.description.fil Fil: Calandri, Ismael Luis. Fleni. Departamento de Neurología. Servicio de Neurología Cognitiva, Neuropsicología y Neuropsiquiatría; Argentina.
dc.relation.ispartofVOLUME 16
dc.relation.ispartofNUMBER 4
dc.relation.ispartofPAGINATION e70033
dc.relation.ispartofCOUNTRY Estados Unidos
dc.relation.ispartofCITY Hoboken, NJ
dc.relation.ispartofTITLE Alzheimer's & dementia : diagnosis, assessment & disease monitoring.
dc.relation.ispartofISSN 2352-8729
dc.type.snrd info:ar-repo/semantics/artículo es_ES


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