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Now showing items 59-78 of 125

First presentation with neuropsychiatric symptoms in autosomal dominant Alzheimer's disease: the Dominantly Inherited Alzheimer's Network Study

O'Connor, Antoinette; Rice, Helen; Barnes, Josephine; Ryan, Natalie S.; Liu, Kathy Y.; Allegri, Ricardo Francisco; Berman, Sarah B.; Ringman, John M.; Cruchaga, Carlos; Farlow, Martin R.; Hassenstab, Jason; Lee, Jae-Hong; Perrin, Richard J.; Xiong, Chengjie; Gordon, Brian A.; Levey, Allan I.; Goate, Alison M.; Graff-Radford, Neill R.; Levin, Johannes; Dominantly Inherited Alzheimer Network (BMJ Publishing Group, 2022-12-15)
Gender inequalities as contributors to dementia in Latin America and the Caribbean: what factors are missing from research?

Ribeiro, Fabiana S.; Crivelli, Lucía; Leist, Anja K. (Elsevier, 2023-05-11)

The current knowledge of modifiable risk factors for dementia comes mainly from high-income countries. In Latin America and Caribbean countries, where the burden of gender and socioeconomic inequalities is greater than in ...
Impact of Social Isolation on People with Dementia and Their Family Caregivers

Dos Santos Azevedo, Lílian Viana; Calandri, Ismael Luis; Slachevsky, Andrea; Graviotto, Héctor Gastón; Santos Vieira, Maria Carolina; Bezerra de Andrade, Caíssa; Peredo Rossetti, Adriana; Barroso Generoso, Alana; Carvalho Carmona, Karoline; Aparecida Cardoso Pinto, Ludmilla; Sorbara, Marcos; Pinto, Alejandra; Guajardo, Tania; Olavarría, Loreto; Thumala, Daniela; Crivelli, Lucía; Vivas, Ludmila; Allegri, Ricardo Francisco; Tonidandel Barbosa, Maira; Serrano, Cecilia M. (IOS, 2021-03-30)

Background: People with dementia and their family caregivers may face a great burden through social isolation due to the COVID-19 pandemic, which can be manifested as various behavioral and clinical symptoms. Objective: ...
Impaired theory of mind in unaffected first-degree relatives of patients with anorexia nervosa

Tapajóz Pereira de Sampaio, Fernanda; Soneira, Sebastián; Catoira, Natalia; Aulicino, Alfredo; Allegri, Ricardo Francisco (Wiley, 2019-09-08)

OBJECTIVE: Previous studies have shown theory of mind (ToM) is affected in patients with anorexia nervosa (AN). There has also been growing interest in the study of endophenotypes in psychiatric disorders, since they allow ...
Improvement of episodic memory retention by a memory reactivation intervention across the lifespan: from younger adults to amnesic patients

Fernández, Rodrigo Sebastián; Picco, Soledad; Beron, Juan Cruz; Bavassi, Luz; Campos, Jorge; Allegri, Ricardo Francisco; Pedreira, María Eugenia (Nature Pub. Group, 2022-04-05)

Spontaneous reactivation of recently acquired memories is a fundamental mechanism of memory stabilization. Re-exposure to specific learned cues during sleep or awake states, namely targeted memory reactivation, has been ...
Insular functional alterations in emotional processing of schizophrenia patients revealed by Multivariate Pattern Analysis fMRI

Drucaroff, Lucas J.; Fazzito, María Lucía; Castro, Mariana Nair; Nemeroff, Charles B.; Guinjoan, Salvador Martín; Villarreal, Mirta Fabiana (Pergamon Press, 2020-11)

Emotion perception is impaired in schizophrenia patients (SP) and related to reduced social skills performance. There is a remarkable variability across subjects for functional neuroimaging alterations related to this ...
Is the binge-eating disorder a circadian disorder?

Plano, Santiago Andrés; Soneira, Sebastián; Tortello, Camila; Golombek, Diego Andrés (Frontiers Media S. A., 2022-07-22)
La investigación y los investigadores clínicos continúan huérfanos en el sistema nacional de ciencia y técnica…

Allegri, Ricardo Francisco (Fundación Revista Medicina (Buenos Aires), 2020-07)
Latin America has been under-represented in dementia clinical trials, we must turn the corner

Allegri, Ricardo Francisco; Román, Fabián; Barceló Martínez, Ernesto (Universidad de la Costa, 2022-06-11)

The world’s population is aging, life expectancy is increasing in the past century as result of the improvements in healthcare and the people arrive to live longer and healthier. However, this has also resulted in increase ...
Latin American Initiative for Lifestyle Intervention to Prevent Cognitive Decline (LatAm-FINGERS): Study design and harmonization

Crivelli, Lucía; Calandri, Ismael Luis; Kimie Suemoto, Claudia; Salinas, Rosa María; Velilla, Lina M.; Sanches Yassuda, Mónica; Caramelli, Paulo; Lopera, Francisco; Nitrini, Ricardo; Sevlever, Gustavo Emilio; Sosa, Ana Luisa; Acosta, Daisy; Bérgamo, Yanina; Clarens, María Florencia; Demey, Ignacio; Helou, María Belén; Martin, María Eugenia; Querzé, Diego; Surace, Ezequiel Ignacio; Allegri, Ricardo Francisco (Wiley, 2023-05-19)

Introduction: Latin American Initiative for Lifestyle Intervention to Prevent Cognitive Decline (LatAm-FINGERS) is the first non-pharmacological multicenter randomized clinical trial (RCT) to prevent cognitive impairment ...
Living with dementia: increased level of caregiver stress in times of COVID-19

Cohen, Gabriela; Russo, María Julieta; Campos, Jorge; Allegri, Ricardo Francisco (Cambridge University Press, 2020-11)

COVID-19 pandemic in Argentina has affected the care of older adults with dementia deeply. Our objective was to study how the obligatory social isolation affected stress caregiver and burden of care of family members of ...
Longitudinal Accumulation of Cerebral Microhemorrhages in Dominantly Inherited Alzheimer Disease

Joseph-Mathurin, Nelly; Wang, Guoquiao; Kantarci, Kejal; Jack Jr, Clifford R.; McDade, Eric; Hassenstab, Jason; Blazey, Tyler M.; Gordon, Brian A.; Su, Yi; Chen, Gengsheng; Massoumzadeh, Parinaz; Hornbeck, Russ C.; Allegri, Ricardo Francisco; Ances, Beau M.; Berman, Sarah B.; Brickman, Adam M.; Brooks, William S.; Cash, David M.; Chhatwal, Jasmeer P.; Dominantly Inherited Alzheimer Network (AAN, 2021-01-25)

Objective: To investigate the inherent clinical risks associated with the presence of cerebral microhemorrhages (CMHs) or cerebral microbleeds (CMBs) and characterize individuals at high risk for developing hemorrhagic ...
Longitudinal clinical, cognitive and biomarker profiles in dominantly inherited versus sporadic early-onset Alzheimer's disease

Llibre Guerra, Jorge J.; Iaccarino, Leonardo; Coble, Dean; Edwards, Lauren; Li, Yan; McDade, Eric; Strom, Amelia; Gordon, Brian; Mundada, Nidhi; Schindler, Suzanne E.; Tsoy, Elena; Ma, Yinjiao; Lu, Ruijin; Fagan, Anne M.; Benzinger, Tammie L. S.; Soleimani-Meigooni, David; Aschenbrenner, Andrew J.; Allegri, Ricardo Francisco; Patricio Alexis, Chrem Méndez; Surace, Ezequiel Ignacio (Oxford University Press, 2023-10-18)

Approximately 5% of Alzheimer's disease cases have an early age at onset (<65 years), with 5-10% of these cases attributed to dominantly inherited mutations and the remainder considered as sporadic. The extent to which ...
Loss of Direct Vascular Contact to Astrocytes in the Hippocampus as an Initial Event in Alzheimer's Disease. Evidence from Patients, In Vivo and In Vitro Experimental Models

Pomilio, Carlos; Presa, Jessica; Oses, Camila; Vinuesa, Ángeles; Bentivegna, Melisa; Gregosa, Amal; Riudavets, Miguel; Sevlever, Gustavo Emilio; Galvan, V.; Levi, V.; Beauquis, Juan; Saravia, Flavia (Humana Press, 2024-01-03)

Alzheimer's disease (AD) is characterized by the accumulation of aggregated amyloid peptides in the brain parenchyma and within the walls of cerebral vessels. The hippocampus-a complex brain structure with a pivotal role ...
Medición del entrenamiento musical como indicador de reserva cognitiva: adaptación y validación de la versión argentina del Musical Training Questionnaire

Feldberg, Carolina; Stefani, Dorina; Moya García, Lydia; Mailing, Ingrid; Caruso, Guido; Somale, María Verónica; Allegri, Ricardo Francisco (Sociedad Neurológica Argentina, 2019-02-04)

Introducción La participación en actividades del tiempo libre, especialmente el entrenamiento musical, puede ser un posible indicador de la reserva cognitiva (RC) del sujeto. La relevancia de su estudio consiste en ...
Microglial autophagy is impaired by prolonged exposure to β-amyloid peptides: evidence from experimental models and Alzheimer's disease patients

Pomilio, Carlos; Gorojod, Roxana M.; Riudavets, Miguel; Vinuesa, Ángeles; Presa, Jessica; Gregosa, Amal; Bentivegna, Melisa; Alaimo, Agustina; Porte Alcon, Soledad; Sevlever, Gustavo Emilio; Kotler, Monica L.; Beauquis, Juan; Saravia, Flavia (Springer, 2020-01-23)

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by the presence of misfolded proteins, amyloid-β (Aβ) aggregates, and neuroinflammation in the brain. Microglial cells are key players in ...
Moving from neurodegenerative dementias, to cognitive proteinopathies, replacing "where" by "what"…

Allegri, Ricardo Francisco (Associação Neurologia Cognitiva e do Comportamento, 2020-07)

Neurodegenerative dementias have been described based on their phenotype, in relation to selective degeneration occurring in a particular neuroanatomical system. More recently however, the term proteinopathy has been ...
Multimodal brain age estimates relate to Alzheimer disease biomarkers and cognition in early stages: a cross-sectional observational study

Millar, Peter R.; Gordon, Brian A.; Luckett, Patrick H.; Benzinger, Tammie L.S.; Cruchaga, Carlos; Fagan, Anne M.; Hassenstab, Jason; Perrin, Richard J.; Schindler, Suzanne E.; Allegri, Ricardo Francisco; Day, Gregory S.; Farlow, Martin R.; Mori, Hiroshi; Nübling, Georg; Dominantly Inherited Alzheimer Network; Bateman, Randall J.; Morris, John C.; Ances, Beau M. (eLife Sciences Publications, 2023-01-06)

Background: Estimates of 'brain-predicted age' quantify apparent brain age compared to normative trajectories of neuroimaging features. The brain age gap (BAG) between predicted and chronological age is elevated in symptomatic ...
Music Based Assessment for Cognitive Functions for Spanish-Speaking Adults With Acquired Brain Injury (ECMUS): A Pilot-Validation Study

Pfeiffer, Camila Floreana; Hanser, Suzanne; Russo, María Julieta; Goyheneix, Mercedes; Oliva, Miguel; Codding, Peggy; Allegri, Ricardo Francisco (Oxford University Press, 2021-07-23)

Acquired brain injury (ABI) commonly causes cognitive dysfunction that needs to be assessed and treated to maximize rehabilitation outcomes. Research suggests that music, emotion, and cognition are intimately linked, and ...
Network analysis of pandemic fatigue symptoms in samples from five South American countries

Caycho-Rodríguez, Tomás; Torales, Julio; Ventura-León, José; Barrios, Iván; Waisman Campos, Marcela; Terrazas-Landivar, Alexandra; Viola, Laura; Vilca, Lindsey W.; Muñoz-Del-Carpio-Toia, Agueda (Sage Publications, 2024-01-26)

Background: Pandemic fatigue generates low motivation or the ability to comply with protective behaviors to mitigate the spread of COVID-19. Aims: This study aimed to analyze the symptoms of pandemic fatigue through ...

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