Enfermedades Desmielinizantes: Recent submissions

  • Interleukin-35 is a critical regulator of immunity during helminth infections associated with multiple sclerosis 
    Correale, Jorge; Marrodán, Mariano; Carnero Contentti, Edgar (Wiley, 2021-07-01)
    Multiple sclerosis (MS) is currently thought to arise by interactions between genetic susceptibility and environmental factors. Infections in general trigger autoimmune responses causing clinical manifestations of disease. ...
  • Research priorities in multiple sclerosis in Latin America: A multi-stakeholder call to action to improve patients care: Research priorities in MS in LATAM 
    Rojas, Juan Ignacio; Carnero Contentti, Edgar; Abad, Patricio; Aguayo, Adriana; Alonso, Ricardo; Bauer, Johana; Becker, Jefferson; Bustos, Andrea K.; Carcamo, Claudia A.; Carrá, Adriana; Correa Díaz, Edgar Patricio; Correale, Jorge; Cristiano, Edgardo; Diaz, Alejandro J.; Fernandez Liguori, Nora; Flores, José; Fruns, Manuel; Garcea, Orlando; Ysrraelit, María Célica; LACTRIMS working group (Elsevier, 2021-05-24)
    As human and economic resources are limited, especially in Latin America (LATAM), it is important to identify research priorities to improve multiple sclerosis (MS) patients care in the region. The objective was to generate ...
  • Multiple sclerosis care units in Latin America: Consensus recommendations about its objectives and functioning implementation 
    Cristiano, Edgardo; Abad, Patricio; Becker, Jefferson; Carrá, Adriana; Correale, Jorge; Flores, José; Fruns, Manuel; Garcea, Orlando; Garcia Bónitto, Juan; Gracia, Fernando; Hamuy, Fernando; Navas, Carlos; Patrucco, Liliana; Rivera, Víctor M.; Velazquez, Merced; Rojas, Juan Ignacio (Elsevier, 2021-10-15)
    Objective Currently, there are several reasons to promote worldwide the concept of multiple sclerosis care units (MSCU) for a better management of affected patients. Ideally, the MSCU should have some human and technical ...
  • Guías de práctica para indicación y contraindicaciones de vacunación de pacientes con esclerosis múltiple 
    Barboza, Andrés G.; Sinay, Vladimiro; Silva, Berenice Anabel; Rojas, Juan Ignacio; Ysrraelit, María Célica; Carnero Contentti, Edgar; Negrotto, Laura; Tavolini, Darío; Deri, Norma; Tizio, Santiago; Gaitán, María Inés; Luetic, Geraldine G.; Patrucco, Liliana; Martínez, Alejandra Diana; Parada Marcilla, Marcela; Hryb, Javier Pablo; Alonso, Ricardo; Bestoso, Santiago; Cabrera, Lorena M.; Cristiano, Edgardo (Elsevier, 2021-03)
    Introducción La esclerosis múltiple es una enfermedad con componente autoinmune, y un número significativo de pacientes se encuentra bajo tratamiento inmunomodulador e inmunosupresor. Frecuentemente los médicos tratantes ...
  • LB82 Effect of Ofatumumab on Serum Immunoglobulin Levels and Infection Risk in Relapsing Multiple Sclerosis Patients from the Phase 3 ASCLEPIOS I and II Trials 
    de Seze, Jerome; Bar-Or, Amit; Correale, Jorge; Cross, Anne H.; Kappos, Ludwig; Selmaj, Krzysztof; Wiendl, Heinz; Kerloeguen, Cecile; Goodyear, Alexandra; Pingili, Ratnakar; Sullivan, Roseanne; Gupta, Ayan Das; Jehl, Valentine; Häring, Dieter A.; Merschhemke, Martin; Hauser, Stephen L. (Wiley, 2020-05)
  • Accumulative risk of clinical event in high-risk radiologically isolated syndrome in Argentina: data from the nationwide registry RelevarEM 
    Rojas, Juan Ignacio; Pappolla, Agustín; Blaya, Patricio A.; Marrodán, Mariano; Ysrraelit, María Célica; Luetic, Geraldine G.; Liwacki, Susana; Barboza, Andrés G.; Burgos, Marcos; Cohen, Leila; Mainella, Carolina; Zanga, Gisela; Menichini, María Laura; Tavolini, Darío; Tkachuk, Verónica A.; López, Pablo Adrián; Leguizamon, Felisa; Knorre, Eduardo; Nofal, Pedro G.; Patrucco, Liliana (Springer, 2021-09-07)
    Introduction: We aimed to analyze the accumulative risk of MRI and OB factors for evolution from RIS to MS in subjects included in the Argentinean MS registry (NCT03375177). Methods: RIS subjects were identified according ...
  • BTK inhibitors as potential therapies for multiple sclerosis 
    Correale, Jorge (Elsevier, 2021-08-19)
    Resumen no disponible
  • Social Cognition In Early Multiple Sclerosis: Neuropsychological And Anatomical Approach 
    Crivelli, Lucía; Calandri, Ismael Luis; Helou, María Belén; Keller, Greta; Fiol, Marcela Paula; Ysrraelit, María Célica; Gaitán, María Inés; Correale, Jorge (Universidad de la Costa, 2021-03-27)
    Cognitive impairment and deficits in social cognition (SC) are frequent in patients with multiple sclerosis (MS). The aim of the present work is to study SC in patients with early MS and to analyze its neuroanatomical ...
  • Assessing attacks and treatment response rates among adult patients with NMOSD and MOGAD: Data from a nationwide registry in Argentina 
    Carnero Contentti, Edgar; López, Pablo Adrián; Pettinicchi, Juan Pablo; Criniti, Juan; Pappolla, Agustín; Miguez, Jimena; Patrucco, Liliana; Cristiano, Edgardo; Liwacki, Susana; Tkachuk, Verónica A.; Balbuena Aguirre, María Eugenia; Vrech, Carlos; Deri, Norma; Correale, Jorge; Marrodán, Mariano; Ysrraelit, María Célica; Leguizamon, Felisa; Luetic, Geraldine G.; Menichini, María Laura; Tavolini, Darío (Sage Publications, 2021-08-20)
    Abstract We aimed to examine treatment interventions implemented in patients experiencing neuromyelitis optica spectrum disorders (NMOSD) attacks (frequency, types, and response). Methods Retrospective study. Data on ...
  • LB62 Ofatumumab vs Teriflunomide in Relapsing Multiple Sclerosis: Analysis of No Evidence of Disease Activity (NEDA-3) from ASCLEPIOS I and II Trials 
    Hauser, Stephen L.; Bar-Or, Amit; Cohen, Jeffrey A.; Comi, Giancarlo; Correale, Jorge; Coyle, Patricia K.; Cross, Anne H.; de Seze, Jerome; Montalban, Xavier; Selmaj, Krzysztof; Wiendl, Heinz; Willi, Roman; Li, Bingbing; Häring, Dieter A.; Ramnathan, Krishnan; Merschhemke, Martin; Kappos, Ludwig (Wiley, 2020-05-27)
  • Therapeutic plasma exchange in MS refractory relapses: Long-term outcome 
    Marrodán, Mariano; Crema, Santiago; Rubstein, Adrián; Alessandro, Lucas; Fernández, José; Correale, Jorge; Ysrraelit, María Célica (Elsevier, 2021-07-25)
    Introduction Therapeutic plasma exchange (TPE) is considered a treatment option for steroid-refractory multiple sclerosis (MS) relapses. Our objective was to assess long-term clinical response to TPE in MS steroid-refractory ...
  • Status of the neuromyelitis optica spectrum disorder in Latin America 
    Rivera, Víctor M.; Hamuy, Fernando; Rivas, Verónica; Gracia, Fernando; Rojas, Juan Ignacio; Bernardi Bichuetti, Denis; Villa, Andrés; Daccach Marques, Vanessa; Soto, Arnoldo; Bertado, Brenda; Treviño Frenk, Irene; Galleguillos Goiry, Lorna; Quiñones, Jairo; Ramírez, Deyanira A.; Caparo Zamalloa, César; Ciampi, Ethel; Lana Peixoto, Marco A.; Rodríguez, Emmanuel; Zarco, Luis; Correale, Jorge (Elsevier, 2021-06-14)
    Background Neuromyelitis optica spectrum disorders (NMOSD) is an increasing diagnostic and therapeutic challenge in Latin America (LATAM). Despite the heterogeneity of this population, ethnic and socioeconomic commonalities ...
  • Real-world effectiveness of natalizumab treatment in patients with relapsing multiple sclerosis in Argentina and Chile 
    Ysrraelit, María Célica; Caride, Alejandro; Sinay, Vladimiro; Rivera Kindel, Mario; Halfon, Mario Javier; Patrucco, Liliana; Piedrabuena, Raúl; Diaz Aragunde, Vanina Eleonor (Associacao Arquivos De Neuro-Psiquitria Dr Oswaldo Lange, 2021-05-01)
    Background: The real-world effectiveness of natalizumab in people with relapsing multiple sclerosis (PwRMS) in Argentina and Chile has not been reported. Objective: To evaluate the effectiveness of natalizumab treatment ...
  • Rituximab- and ocrelizumab-induced early- and late-onset neutropenia in a multiple sclerosis patient 
    Marrodán, Mariano; Laviano, Julia; Oneto, Sofía; Reino, Fabricio M.; Delorme, Ricardo; Fornillo, Florencia; Fernández, José; Correale, Jorge (Springer, 2021-06-01)
    Resumen no disponible
  • Aggressive multiple sclerosis in Argentina: Data from the nationwide registry RelevarEM 
    Kohler, Matías; Kohler, Eduardo; Vrech, Carlos; Pappolla, Agustín; Miguez, Jimena; Patrucco, Liliana; Correale, Jorge; Marrodán, Mariano; Gaitán, María Inés; Fiol, Marcela Paula; Negrotto, Laura; Ysrraelit, María Célica; Cristiano, Edgardo; Carrá, Adriana; Steinberg, Judith; Martinez, Alejandra D.; Curbelo, María Celeste; Cohen, Leila; Alonso, Ricardo; Garcea, Orlando (Elsevier, 2021-06-01)
    The objectives of the present study were to describe the frequency of aggressive multiple sclerosis (aMS) as well as to compare clinical and radiological characteristics in aMS and non-aMS patients included in RelevarEM ...
  • Editorial: Immunosuppressive Amino Acid Catabolizing Enzymes in Heallth and Disease 
    Castellano, Flavia; Correale, Jorge; Molinier-Frenkel, Valerie (Frontiers Research Foundation, 2021-05-05)
    Resumen no disponible
  • Combination therapy of apo-transferrin and thyroid hormones enhances remyelination 
    Rosato-Siri, María Victoria; Marziali, Leandro Nazareno; Mattera, Vanesa S.; Correale, Jorge; Pasquini, Juana María (Wiley-Liss, 2020-08-20)
    The current study presents two different approaches with a view to elucidating the interaction between thyroid hormones (TH) and apo-transferrin (aTf) and their role in myelination and remyelination. First, in vitro assays ...
  • GAS6 signaling tempers Th17 development in patients with multiple sclerosis and helminth infection 
    Ortiz Wilczyñski, Juan M.; Olexen, Cinthia M.; Errasti, Andrea E.; Schattner, Mirta; Rothlin, Carla V.; Correale, Jorge; Carrera Silva, Eugenio A. (Public Library of Science, 2020-11-21)
    Multiple sclerosis (MS) is a highly disabling neurodegenerative autoimmune condition in which an unbalanced immune response plays a critical role. Although the mechanisms remain poorly defined, helminth infections are known ...
  • Absence of latitudinal gradient in oligoclonal bands prevalence in Argentina 
    Negrotto, Laura; Marrodán, Mariano; Fiol, Marcela Paula; Gaitán, María Inés; Ysrraelit, María Célica; Vrech, Carlos; Pappolla, Agustín; Miguez, Jimena; Patrucco, Liliana; Cristiano, Edgardo; Rojas, Juan Ignacio; Carrá, Adriana; Chertcoff, Aníbal; Steinberg, Judith; Martinez, Alejandra D.; Curbelo, María Celeste; Cohen, Leila; Alonso, Ricardo; Garcea, Orlando; Correale, Jorge (Elsevier, 2020-11)
    Background: Like MS prevalence, oligoclonal bands (OCB) frequency seems to follow a latitudinal gradient. Argentina is extensive, latitude-wise, and previous studies have not found an MS prevalence latitudinal gradient. ...
  • Aspectos clínicos y demográficos de los pacientes con esclerosis múltiple secundaria progresiva en Argentina 
    Gaitán, María Inés; Marrodán, Mariano; Negrotto, Laura; Ysrraelit, María Célica; Miguez, Jimena; Alonso Serena, Marina; Pappolla, Agustín; Patrucco, Liliana; Cristiano, Edgardo; Vrech, Carlos; Rojas, Juan Ignacio; Grupo de Trabajo Relevar EM (Fundación Revista Medicina (Buenos Aires), 2020)
    El objetivo del estudio fue evaluar los aspectos clínicos y demográficos de los pacientes con esclerosis múltiple (EM) secundaria progresiva (EMSP) en los pacientes incluidos en el Registro Argentino de EM (RelevarEM, ...

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