Enfermedades Desmielinizantes: Recent submissions

  • Differential diagnosis in acute inflammatory myelitis 
    Marrodán, Mariano; Hernandez, Micaela Anahí; Kohler, Alejandro Alfredo; Correale, Jorge (Elsevier, 2020-11)
    Introduction: Establishing differential diagnosis between different inflammatory causes of acute transverse myelitis (ATM) can be difficult. The objective of this study was to see which clinical, imaging or laboratory ...
  • Obesity and the risk of Multiple Sclerosis. The role of Leptin 
    Marrodán, Mariano; Farez, Mauricio Franco; Balbuena Aguirre, María Eugenia; Correale, Jorge (Wiley Periodicals, 2021-02)
    Objective: To investigate the effects of leptin on different T-cell populations, in order to gain more insight into the link between leptin and obesity. Methods: Three hundred and nine RRMS patients and 322 controls ...
  • Emerging drugs for the treatment of adult MOG-IgG-associated diseases 
    Carnero Contentti, Edgar; Marrodán, Mariano; Correale, Jorge (Taylor & Francis, 2021-04-16)
    Resumen no disponible
  • Ofatumumab versus Teriflunomide in Multiple Sclerosis 
    Hauser, Stephen L.; Bar-Or, Amit; Comi, Giancarlo; Correale, Jorge; Coyle, Patricia K.; Cross, Anne H.; de Seze, Jerome; Leppert, David; Montalban, Xavier; Selmaj, Krzysztof; Wiendl, Heinz; Kerloeguen, Cecile; Willi, Roman; Li, Bingbing; Kakarieka, Algirdas; Tomic, Davorka; Goodyear, Alexandra; Pingili, Ratnakar; ASCLEPIOS I and ASCLEPIOS II Trial Groups (Massachusetts Medical Society, 2020-08-06)
    Background: Ofatumumab, a subcutaneous anti-CD20 monoclonal antibody, selectively depletes B cells. Teriflunomide, an oral inhibitor of pyrimidine synthesis, reduces T-cell and B-cell activation. The relative effects of ...
  • COVID-19 in multiple sclerosis and neuromyelitis optica spectrum disorder patients in Latin America: COVID-19 in MS and NMOSD patients in LATAM 
    Alonso, Ricardo; Silva, Berenice Anabel; Garcea, Orlando; Correa Díaz, Edgar Patricio; Rodrigues Dos Passos, Giordani; Ramirez Navarro, Deyanira A.; Garcia Valle, Luis A.; Rodriguez Salinas, Luis C.; Negrotto, Laura; Luetic, Geraldine G.; Tkachuk, Verónica A.; Míguez, Jimena S.; Hamuy, Fernando; Goiry, Lorna Galleguillos; Ramírez Sánchez, Nicia E.; Burgos, Marcos; Steinberg, Judith; Balbuena Aguirre, María Eugenia; Monterrey Alvarez, Priscilla; Ysrraelit, María Célica (Elsevier, 2021-03-07)
    Background: There is no data regarding COVID-19 in Multiple Sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) patients in Latin America. Objective: The objective of this study was to describe the clinical ...
  • Iron Metabolism in Oligodendrocytes and Astrocytes, Implications for Myelination and Remyelination 
    Cheli, Veronica Teresita; Correale, Jorge; Paez, Pablo M.; Pasquini, Juana María (Sage, 2020-01)
    Iron is a key nutrient for normal central nervous system (CNS) development and function; thus, iron deficiency as well as iron excess may result in harmful effects in the CNS. Oligodendrocytes and astrocytes are crucial ...
  • Spinal cord and brain MRI should be routinely performed during follow-up in patients with NMOSD - Yes 
    Carnero Contentti, Edgar; Correale, Jorge (Sage, 2021-01)
  • Latin American consensus recommendations for management and treatment of neuromyelitis optica spectrum disorders in clinical practice 
    Carnero Contentti, Edgar; Rojas, Juan Ignacio; Cristiano, Edgardo; Daccach Marques, Vanessa; Flores, José; Lana Peixoto, Marco A.; Navas, Carlos; Papais Alvarenga, Regina; Sato, Douglas K; Soto de Castillo, Ibis; Correale, Jorge (Elsevier, 2020-10)
    Background: During the last two decades, neuromyelitis optica spectrum disorder (NMOSD) has undergone important changes, with new diagnostic markers and criteria, better recognition of clinical phenotypes, better disease ...
  • Bruton's tyrosine kinase inhibitors: a promising emerging treatment option for multiple sclerosis 
    Carnero Contentti, Edgar; Correale, Jorge (Taylor & Francis, 2020-12)
  • Usage trend of oral drugs for multiple sclerosis patients in Argentina 
    Alonso, Ricardo; Garcea, Orlando; Eizaguirre, María Barbara; Man, Federico; Lopez Bizzo, Abril; Cohen, Leila; Rojas, Juan Ignacio; Patrucco, Liliana; Cristiano, Edgardo; Pita, Cecilia; Tkachuk, Verónica A.; Balbuena Aguirre, María Eugenia; Carnero Contentti, Edgar; López, Pablo Adrián; Pettinicchi, Juan Pablo; Deri, Norma; Miguez, Jimena; Pappolla, Agustín; Lázaro, Luciana; Fernández Liguori, Nora; Correale, Jorge; Carrá, Adriana; Silva, Berenice Anabel (Elsevier, 2020-12-02)
    Introduction: Over the past decade, numerous disease modifying drugs (DMDs) for relapsing- remitting multiple sclerosis (RRMS) have been approved in Argentina. The use of oral DMDs (oDMDs) has increased in recent years, ...
  • Immunosuppressive Amino-Acid Catabolizing Enzymes in Multiple Sclerosis 
    Correale, Jorge (Frontiers Research Foundation, 2021-01-20)
    Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease that affects the central nervous system. Although the pathogenesis of MS is not yet fully elucidated, several evidences suggest that autoimmune processes ...
  • Prevalence of C9orf72 hexanucleotide repeat expansion in Greek patients with sporadic ALS 
    Sokratous, Maria; Schottlaender, Lucía V.; Bourinaris, Thomas; Marogianni, Chrysoula; Arnaoutoglou, Marianthi; Patrikiou, Eleni; Ralli, Styliani; Markou, Aikaterini; Dardiotis, Efthimios; Houlden, Henry; Hadjigeorgiou, Georgios M.; Xiromerisiou, Georgia (Taylor & Francis, 2020-07)
    A total of 178 consecutive patients with definite sALS without frontotemporal dementia (FTD) were enrolled in this study, after complete clinical evaluation. A Repeat-Primed Polymerase Chain Reaction (RP-PCR) protocol was ...
  • Radiologically isolated syndrome: from biological bases to practical management 
    Barboza, Andrés G.; Carnero Contentti, Edgar; Curbelo, María Celeste; Halfon, Mario Javier; Rojas, Juan Ignacio; Silva, Berenice Anabel; Sinay, Vladimiro; Tizio, Santiago; Ysrraelit, María Célica; Alonso, Ricardo (Springer, 2021-01-25)
    Background: Technological advances and greater availability of magnetic resonance imaging have prompted an increment on incidental and unexpected findings within the central nervous system. The concept of radiologically ...
  • What percentage of AQP4-ab-negative NMOSD patients are MOG-ab positive? A study from the Argentinean multiple sclerosis registry (RelevarEM) 
    Carnero Contentti, Edgar; López, Pablo Adrián; Pettinicchi, Juan Pablo; Pappolla, Agustín; Miguez, Jimena; Patrucco, Liliana; Cristiano, Edgardo; Vrech, Carlos; Tkachuk, Verónica A.; Liwacki, Susana; Correale, Jorge; Marrodán, Mariano; Gaitán, María Inés; Fiol, Marcela Paula; Negrotto, Laura; Ysrraelit, María Célica; Burgos, Marcos; Leguizamon, Felisa; Tavolini, Darío; Deri, Norma (Elsevier, 2021-01-07)
    Background Myelin oligodendrocyte glycoprotein antibodies (MOG-ab) have been described in aquaporin-4-antibodies(AQP4-ab)-negative neuromyelitis optica spectrum disorder (NMOSD) patients. We aimed to evaluate the percentage ...
  • Vasculitic Peripheral Neuropathy, Differences Between Systemic and Non-Systemic Etiologies: A Case Series and Biopsy Report 
    Castiglione, Juan Ignacio; Marrodán, Mariano; Alessandro, Lucas; Taratuto, Ana Lía; Brand, Patricio; Nogués, Martín; Barroso, Fabio Adrián (IOS, 2021-01-01)
    Background:Vasculitic peripheral neuropathy (VPN) is caused by vessel inflammation leading to peripheral nerve injury of acute-to-subacute onset. When VPN occurs in the context of systemic disease it is classified as ...
  • Multiple sclerosis and neuromyelitis optica spectrum disorders in Argentina: comparing baseline data from the Argentinean MS Registry (RelevarEM) 
    Rojas, Juan Ignacio; Alonso Serena, Marina; Garcea, Orlando; Patrucco, Liliana; Carrá, Adriana; Correale, Jorge; Vrech, Carlos; Pappolla, Agustín; Miguez, Jimena; Doldan, María L.; Silveira, Facundo Oscar; Alonso, Ricardo; Cohen, Leila; Pita, Cecilia; Silva, Berenice Anabel; Fiol, Marcela Paula; Gaitán, María Inés; Marrodán, Mariano; Negrotto, Laura; Ysrraelit, María Célica; RelevarEM investigators (Springer-Verlag, 2020-06)
    The objective of this study was to describe and compare the baseline epidemiological data of multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) patients included in RelevarEM (Clinical Trials registry ...
  • Consenso sobre la identificación y seguimiento de la esclerosis múltiple secundaria progresiva en Argentina 
    Cristiano, Edgardo; Patrucco, Liliana; Ysrraelit, María Célica; Alonso, Ricardo; Balbuena Aguirre, María Eugenia; Ballario, Carlos; Barboza, Andrés G.; Bestoso, Santiago; Burgos, Marcos; Cáceres, Fernando; Carrá, Adriana; Carnero Contentti, Edgar; Deri, Norma; Fernández-Liguori, Nora; Garcea, Orlando; Hryb, Javier Pablo; Jacobo, Miguel; Kohler, Eduardo; Luetic, Geraldine G.; Mainella, Carolina (Revista de Neurología, 2021-01-01)
    Introducción. Existen diferencias significativas en el diagnóstico, la identificación y el seguimiento de pacientes con esclerosis múltiple secundaria progresiva (EMSP) entre los profesionales de la salud a cargo de su ...
  • Extracellular vesicles containing the transferrin receptor as nanocarriers of apotransferrin 
    Mattera, Vanesa S.; Pereyra Gerber, Pehuén; Glisoni, Romina; Ostrowski, Matias; Verstraeten, Sandra V.; Pasquini, Juana María; Correale, Jorge (Raven Press, 2020-11)
    Previous work by our group has shown the pro-differentiating effects of apotransferrin (aTf) on oligodendroglial cells in vivo and in vitro. Further studies showed the remyelinating effect of aTf in animal demyelination ...
  • Spinal Cord Involvement in MS and Other Demyelinating Diseases 
    Marrodán, Mariano; Gaitán, María Inés; Correale, Jorge (MDPI, 2020-05-22)
    Diagnostic accuracy is poor in demyelinating myelopathies, and therefore a challenge for neurologists in daily practice, mainly because of the multiple underlying pathophysiologic mechanisms involved in each subtype. A ...
  • Consensus recommendations for family planning and pregnancy in multiple sclerosis in argentina 
    Liguori, Nora Fernández; Alonso, Ricardo; Pinheiro, Amelia Alves; Balbuena Aguirre, María Eugenia; Barboza, Andrés G.; Bestoso, Santiago; Burgos, Marcos; Cáceres, Fernando; Carnero Contentti, Edgar; Carrá, Adriana; Cristiano, Edgardo; Curbelo, María Celeste; Deri, Norma; Fiol, Marcela Paula; Gaitán, María Inés; Garcea, Orlando; Halfon, Mario Javier; Hryb, Javier Pablo; Jacobo, Miguel; José, Gustavo; Knorre, Eduardo; López, Pablo Adrián; Luetic, Geraldine G.; Mainella, Carolina; Martínez, Alejandra Diana; Miguez, Jimena; Nofal, Pedro G.; Pagani Cassará, Fátima; Parada Marcilla, Marcela; Piedrabuena, Raúl; Pita, Cecilia; Quarracino, Cecilia; Rojas, Juan Ignacio; Silva, Berenice Anabel; Sinay, Vladimiro; Steinberg, Judith; Tarulla, Adriana; Tavolini, Darío; Tkachuk, Verónica A.; Tizio, Santiago; Villa, Andrés; Vrech, Carlos; Ysrraelit, María Célica; Patrucco, Liliana (Elsevier, 2020-08)
    Background: Multiple sclerosis (MS) is the most common chronic immune-mediated neurological disorder in young adults, more frequently found in women than in men. Therefore, pregnancy-related issues have become an object ...

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