Enfermedades Desmielinizantes: Envíos recientes

  • Towards imaging criteria that best differentiate MS from NMOSD and MOGAD: Large multi-ethnic population and different clinical scenarios 
    Carnero Contentti, Edgar; Rojas, Juan Ignacio; Criniti, Juan; López, Pablo Adrián; Daccach Marques, Vanessa; Soto de Castillo, Ibis; Tkachuk, Verónica A.; Marrodán, Mariano; Correale, Jorge; Farez, Mauricio Franco; Jin Kim, Ho; Hyun, Jae-Won; Messina, Silvia; Mariano, Romina; Rocca, Maria A.; Cacciaguerra, Laura; Filippi, Massimo; Palace, Jacqueline; Juryńczyk, Maciej (Elsevier B. V., 2022-05)
    Background: The "1/3″ brain magnetic resonance imaging (MRI) criteria including 1) a lesion adjacent to the lateral ventricle and in the inferior temporal lobe, or 2) a juxtacortical lesion, or 3) a Dawson finger-type ...
  • Effect of Ofatumumab on Serum Immunoglobulin Levels and Infection Risk in Patients With Relapsing Multiple Sclerosis Over 3.5 Years 
    Wiendl, Heinz; de Seze, Jerome; Bar-Or, Amit; Correale, Jorge; Cross, Anne H.; Kappos, Ludwig; Selmaj, Krzysztof; Winthrop, Kevin; Giacomini, Paul Steven; Sacca, Francesco; Das Gupta, Ayan; Jehl, Valentine; Pingili, Ratnakar; Mancione, Linda; Zielman, Ronald; Hauser, Stephen L. (37th Congress of the European Committee for Treatment and Research in Multiple Sclerosis, 2021-10)
    Resumen no disponible
  • Multiple sclerosis and obesity: The role of adipokines 
    Correale, Jorge; Marrodán, Mariano (Frontiers Research Foundation, 2022-11-15)
    Multiple Sclerosis (MS), a chronic inflammatory disease of the central nervous system that leads to demyelination and neurodegeneration has been associated with various environmental and lifestyle factors. Population-based ...
  • Multiple sclerosis progression: time for a new mechanism-driven framework 
    Kuhlmann, Tanja; Moccia, Marcello; Coetzee, Timothy; Cohen, Jeffrey A.; Graves, Jennifer; Marrie, Ruth Ann; Montalban, Xavier; Yong, V. Wee; Thompson, Alan J.; Reich, Daniel S.; Correale, Jorge; International Advisory Committee on Clinical Trials in Multiple Sclerosis (Lancet Pub. Group, 2022-11-18)
    Traditionally, multiple sclerosis has been categorised by distinct clinical descriptors-relapsing-remitting, secondary progressive, and primary progressive-for patient care, research, and regulatory approval of medications. ...
  • Colony-stimulating factor-1 receptor inhibition attenuates microgliosis and myelin loss but exacerbates neurodegeneration in the chronic cuprizone model 
    Wies Mancini, Victoria Sofía Berenice; Di Pietro, Anabella A.; de Olmos, Soledad; Silva Pinto, Pablo; Vence, Marianela; Marder, Mariel; Igaz, Lionel M.; Marcora, María Silvina; Pasquini, Juana María; Correale, Jorge; Pasquini, Laura Andrea (Oxford, 2022-03)
    Multiple sclerosis (MS), especially in its progressive phase, involves early axonal and neuronal damage resulting from a combination of inflammatory mediators, demyelination, and loss of trophic support. During progressive ...
  • Childhood focal compressive mononeuropathies during the COVID-19 pandemic in Buenos Aires, Argentina 
    Brand, Patricio; Cejas, Claudia Patricia; Rivero, Alberto Daniel (John Wiley & Sons, 2022-05)
    Introduction/aims: Focal peripheral neuropathies are infrequently seen in pediatric patients. The COVID-19 pandemic has disrupted normal life for many people, including complete lockdowns and school closing for long periods ...
  • Association between infections, the microbiome, vaccination, and neuromyelitis optica spectrum disorder 
    Carnero Contentti, Edgar; Correale, Jorge (Sage, 2022-07-28)
    Neuromyelitis optica spectrum disorder (NMOSD) is a devastating antibody-mediated condition of the central nervous system. As in other autoimmune diseases, there is considerable evidence to suggest that NMOSD arises from ...
  • Current Perspectives: Evidence to Date on BTK Inhibitors in the Management of Multiple Sclerosis 
    Carnero Contentti, Edgar; Correale, Jorge (Dove Press Limited, 2022-10-06)
    Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system leading to demyelination and neurodegeneration. Basic and translational studies have shown that B cells and myeloid cells are critical ...
  • Evaluation of the times of disability progression and related factors in patients with primary progressive multiple sclerosis from Argentina 
    Alonso, Ricardo; Garcea, Orlando; Rojas, Juan Ignacio; Alonso Serena, Marina; Lázaro, Luciana; López, Pablo Adrián; Casas, Magdalena; Tkachuk, Verónica A.; Steinberg, Judith; Barboza, Andrés G.; Martínez, Alejandra Diana; Ysrraelit, María Célica; Correale, Jorge; Marrodán, Mariano; Chertcoff, Aníbal; Deri, Norma; Miguez, Jimena; Patrucco, Liliana; Cristiano, Edgardo; Pestchanker, Claudia (Elsevier, 2022-01-02)
    Background PPMS (primary progressive multiple sclerosis) patients represent less than 10% of MS patients in Argentina, men and women were similarly affected and most of them had a severe functional impairment. More rapid ...
  • The role of the gut microbiota in multiple sclerosis 
    Correale, Jorge; Hohlfeld, Reinhard; Baranzini, Sergio E. (Nature Pub. Group, 2022-09)
    During the past decade, research has revealed that the vast community of micro-organisms that inhabit the gut - known as the gut microbiota - is intricately linked to human health and disease, partly as a result of its ...
  • Rebound activity after fingolimod cessation: A case - control study 
    Barboza, Andrés G.; Gaitán, María Inés; Alonso, Ricardo; Ysrraelit, María Célica; Luetic, Geraldine G.; Liwacki, Susana; Patrucco, Liliana; Halfon, Mario Javier; Burgos, Marcos; Mainella, Carolina; Piedrabuena, Raúl; Recchia, Luciano; Steinberg, Judith; Tkachuk, Verónica A.; Zanga, Gisela; Carra, Adriana; Chertcoff, Aníbal; Fernández Liguori, Nora; Lázaro, Luciana; Menichini, María Laura (Elsevier, 2022-02-09)
    Background: There has been an increase in the number of reports of multiple sclerosis (MS) rebound activity (RA), which is usually defined as a severe disease reactivation after natalizumab or fingolimod withdrawal that ...
  • Impact of Andropause on Multiple Sclerosis 
    Ysrraelit, María Célica; Correale, Jorge (Frontiers Research Foundation, 2021-11-05)
    Andropause results from the natural decrease in testosterone levels that occurs with age. In contrast to menopause, which is a universal, well-characterized process associated with absolute gonadal failure, andropause ...
  • Confirming a Historical Diagnosis of Multiple Sclerosis: Challenges and Recommendations 
    Solomon, Andrew J.; Arrambide, Georgina; Brownlee, Wallace J.; Cross, Anne H.; Gaitán, María Inés; Lublin, Fred D.; Makhani, Naila; Mowry, Ellen M.; Reich, Daniel S.; Rovira, Álex; Weinshenker, Brian G.; Cohen, Jeffrey A. (Lippincott Williams & Wilkins, 2022-06)
    Patients with a historical diagnosis of multiple sclerosis (MS)-a patient presenting with a diagnosis of MS made previously and by a different clinician-present specific diagnostic and therapeutic challenges in clinical ...
  • Computational basis of decision-making impairment in multiple sclerosis 
    Fernández, Rodrigo Sebastián; Crivelli, Lucía; Pedreira, María Eugenia; Allegri, Ricardo Francisco; Correale, Jorge (Sage, 2021-12-21)
    Background: Multiple sclerosis (MS) is commonly associated with decision-making, neurocognitive impairments, and mood and motivational symptoms. However, their relationship may be obscured by traditional scoring ...
  • Seasonal variation in attacks of neuromyelitis optica spectrum disorders and multiple sclerosis: Evaluation of 794 attacks from a nationwide registry in Argentina 
    Carnero Contentti, Edgar; López, Pablo Adrián; Pettinicchi, Juan Pablo; Criniti, Juan; Pappolla, Agustín; Miguez, Jimena; Patrucco, Liliana; Cristiano, Edgardo; Liwacki, Susana; Tkachuk, Verónica A.; Balbuena Aguirre, María Eugenia; Vrech, Carlos; Deri, Norma; Correale, Jorge; Marrodán, Mariano; Ysrraelit, María Célica; Leguizamon, Felisa; Luetic, Geraldine G.; Menichini, María Laura; Tavolini, Darío (Elsevier, 2021-12-13)
    Background: Identification of triggers that potentially instigate attacks in neuromyelitis optica spectrum disorders (NMOSD) and multiple sclerosis (MS) has remained challenging. We aimed to analyze the seasonality of NMOSD ...
  • Clinical and demographic characteristics of male MS patients included in the national registry-RelevarEM. Does sex or phenotype make the difference in the association with poor prognosis? 
    Luetic, Geraldine G.; Menichini, María Laura; Vrech, Carlos; Pappolla, Agustín; Patrucco, Liliana; Cristiano, Edgardo; Marrodán, Mariano; Ysrraelit, María Célica; Fiol, Marcela Paula; Correale, Jorge; Cohen, Leila; Alonso, Ricardo; Silva, Berenice Anabel; Casas, Magdalena; Garcea, Orlando; Deri, Norma; Burgos, Marcos; Liwacki, Susana; Tkachuk, Verónica A.; Barboza, Andrés G. (Elsevier, 2021-11-17)
    Background In multiple sclerosis demographics there is a well-known female prevalence and male patients have been less specifically evaluated in clinical studies, though some clinical differences have been reported between ...
  • Guía de práctica clínica: tratamiento sintomático de esclerosis múltiple. Grupo de Trabajo de Enfermedades Desmielinizantes. Sociedad Neurológica Argentina 
    Barboza, Andrés G.; Sinay, Vladimiro; Zanga, Gisela; Alonso, Ricardo; Silva, Berenice Anabel; Saladino, María Laura; Cohen, Leila; Luetic, Geraldine G.; Camerlingo, S.; Ysrraelit, María Célica; Tenembaum, S. N.; Tarulla, Adriana; Carnero Contentti, Edgar; López, Pablo Adrián; Pita, Cecilia; Tavolini, Darío; Steinberg, Judith; Menichini, María Laura; Rojas, Juan Ignacio; Tizio, Santiago (Elsevier, 2022-06-18)
    Introducción El tratamiento sintomático en la esclerosis múltiple (EM) representa uno de los pilares del abordaje global de esta patología. El tratamiento específico de los síntomas tiene como objetivo reducir o eliminar ...
  • The Immune Response in Multiple Sclerosis 
    Rodríguez Murúa, Sofía; Farez, Mauricio Franco; Quintana, Francisco J. (Annual Reviews, 2021-10-04)
    Multiple sclerosis (MS) is a chronic autoimmune, inflammatory, and neurodegenerative disease that affects the central nervous system (CNS). MS is characterized by immune dysregulation, which results in the infiltration of ...
  • Acting centrally or peripherally: A renewed interest in the central nervous system penetration of disease-modifying drugs in multiple sclerosis 
    Correale, Jorge; Halfon, Mario Javier; Jack, Dominic; Rubstein, Adrián; Villa, Andrés (Elsevier, 2021-09-14)
    With the recent approval of cladribine tablets, siponimod and ozanimod, there has been a renewed interest into the extent to which these current generation disease-modifying therapies (DMTs) are able to cross into the ...
  • Neuromyelitis optica spectrum disorders: from pathophysiology to therapeutic strategies 
    Carnero Contentti, Edgar; Correale, Jorge (BioMed Central, 2021-09-16)
    Neuromyelitis optica (NMO) is a chronic inflammatory autoimmune disease of the central nervous system (CNS) characterized by acute optic neuritis (ON) and transverse myelitis (TM). NMO is caused by a pathogenic serum IgG ...

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