Listar Enfermedades Desmielinizantes.artículos por autor "Marcora, María Silvina"

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2-Chlorodeoxyadenosine (Cladribine) preferentially inhibits the biological activity of microglial cells

Aybar, Florencia; Pérez, María Julia; Marcora, María Silvina; Samman, María Eugenia; Marrodán, Mariano; Pasquini, Juana María; Correale, Jorge (Elsevier Science, 2022-01-29)

Cladribine (2CdA) is a synthetic chlorinated purine nucleoside analogue which acts as a pro-drug requiring intracellular phosphorylation to be activated. It is biologically active in selected cell types, which results in ...
Colony-stimulating factor-1 receptor inhibition attenuates microgliosis and myelin loss but exacerbates neurodegeneration in the chronic cuprizone model

Wies Mancini, Victoria Sofía Berenice; Di Pietro, Anabella A.; de Olmos, Soledad; Silva Pinto, Pablo; Vence, Marianela; Marder, Mariel; Igaz, Lionel M.; Marcora, María Silvina; Pasquini, Juana María; Correale, Jorge; Pasquini, Laura Andrea (Oxford, 2022-03)

Multiple sclerosis (MS), especially in its progressive phase, involves early axonal and neuronal damage resulting from a combination of inflammatory mediators, demyelination, and loss of trophic support. During progressive ...

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