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Browsing Enfermedades Desmielinizantes.artículos by Title

Browsing Enfermedades Desmielinizantes.artículos by Title

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  • Latin American consensus recommendations for management and treatment of neuromyelitis optica spectrum disorders in clinical practice 
    Carnero Contentti, Edgar; Rojas, Juan Ignacio; Cristiano, Edgardo; Daccach Marques, Vanessa; Flores, José; Lana Peixoto, Marco; Navas, Carlos; Papais Alvarenga, Regina; Sato, Douglas K; Soto de Castillo, Ibis; Correale, Jorge (Elsevier, 2020-10)
    Background: During the last two decades, neuromyelitis optica spectrum disorder (NMOSD) has undergone important changes, with new diagnostic markers and criteria, better recognition of clinical phenotypes, better disease ...
  • Latin American consensus recommendations on the risk of infections in people with multiple sclerosis treated with disease modifying drugs 
    Silva, Berenice A.; Carnero Contentti, Edgar; Becker, Jefferson; Carranza, José I.; Correa-Díaz, Patricio E.; Galleguillos Goiry, Lorna; Garcea, Orlando; Gracia, Fernando; Hamuy, Fernando; Macías, Miguel Angel; Navas, Carlos; Nuñez, Sebastián; Rojas, Juan Ignacio; Farez, Mauricio Franco; Alonso, Ricardo; López, Pablo (Elsevier, 2023-06-20)
    Introduction: The emergence of several therapeutic options in multiple sclerosis (MS), which significantly modify the immune system functioning, has led to the need for the consideration of additional factors, such as risk ...
  • Long-term follow-up of patients with relapsing multiple sclerosis from the CLARITY/CLARITY Extension cohort of CLASSIC-MS: An ambispective study 
    Giovannoni, Gavin; Boyko, Alexey; Correale, Jorge; Edan, Gilles; Freedman, Mark S.; Montalban, Xavier; Rammohan, Kottil; Stefoski, Dusan; Yamout, Bassem; Leist, Thomas; Aydemir, Aida; Borsi, Laszlo; Verdun di Cantogno, Elisabetta (Sage, 2023-04-03)
    Background: CLASSIC-MS evaluated the long-term efficacy of cladribine tablets in patients with relapsing multiple sclerosis. Objective: Report long-term mobility and disability beyond treatment courses received in ...
  • Mechanisms of Neurodegeneration and Axonal Dysfunction in Progressive Multiple Sclerosis 
    Correale, Jorge; Marrodán, Mariano; Ysrraelit, María Célica (MDPI, 2019-02-20)
    Multiple Sclerosis (MS) is a major cause of neurological disability, which increases predominantly during disease progression as a result of cortical and grey matter structures involvement. The gradual accumulation of ...
  • Menarche, pregnancies, and breastfeeding do not modify long-term prognosis in multiple sclerosis 
    Zuluaga, María I.; Otero Romero, Susana; Rovira, Álex; Perez Hoyos, Santiago; Arrambide, Georgina; Negrotto, Laura; Galán, Ingrid; Río, Jordi; Comabella, Manuel; Nos, Carlos; Arévalo, María Jesus; Vidal Jordana, Angela; Castilló, Joaquín; Rodríguez, Breogán; Midaglia, Luciana; Mulero, Patricia; Mitjana, Raquel; Auger, Cristina; Sastre Garriga, Jaume; Montalban, Xavier; Tintoré, Mar (Lippincott Williams & Wilkins, 2019-03-01)
    Objective: To investigate the effect of menarche, pregnancies, and breastfeeding on the risk of developing multiple sclerosis (MS) and disability accrual using a multivariate approach based on a large prospective cohort ...
  • Microglia-derived extracellular vesicles in homeostasis and demyelination/remyelination processes 
    Wies Mancini, Victoria Sofía Berenice; Mattera, Vanesa S.; Pasquini, Juana María; Pasquini, Laura Andrea; Correale, Jorge (Wiley on behalf of the International Society for Neurochemistry, 2023-12-06)
    Microglia (MG) play a crucial role as the predominant myeloid cells in the central nervous system and are commonly activated in multiple sclerosis. They perform essential functions under normal conditions, such as actively ...
  • Microglial modulation through colony-stimulating factor-1 receptor inhibition attenuates demyelination 
    Wies Mancini, Victoria Sofía Berenice; Pasquini, Juana María; Correale, Jorge; Pasquini, Laura Andrea (Wiley, 2018-11-19)
    Multiple sclerosis (MS) is one of the most common causes of progressive disability affecting young people with very few therapeutic options available for its progressive forms. Its pathophysiology involves demyelination ...
  • Mortality of neuromyelitis optica spectrum disorder patients in an Argentinean population: A study from the RelevarEM registry 
    Carnero Contentti, Edgar; López, Pablo A.; Pettinicchi, Juan Pablo; Criniti, Juan; Pappolla, Agustín; Miguez, Jimena; Cristiano, Edgardo; Patrucco, Liliana; Liwacki, Susana; Tkachuk, Verónica; Balbuena, María E.; Vrech, Carlos; Deri, Norma; Correale, Jorge; Marrodán, Mariano; Ysrraelit, María Célica; Leguizamon, Felisa; Luetic, Geraldine; Menichini, María L.; Tavolini, Darío (Sage, 2023-10-17)
    We aimed to evaluate mortality and causes of death among Argentinean neuromyelitis optica spectrum disorder (NMOSD) patients and identify predictors of death. Retrospective study included 158 NMOSD patients and 11 (7%) ...
  • Mucosal associated invariant T cell features and TCR repertoire characteristics during the course of Multiple Sclerosis 
    Carnero Contentti, Edgar; Farez, Mauricio Franco; Correale, Jorge (Frontiers Research Foundation, 2019-10-31)
    Objective: To investigate the frequency, phenotype, function and longitudinal repertoire of Mucosal-associated invariant T (MAIT) cells in relapsing remitting (RRMS) and primary progressive MS (PPMS) patients Methods: ...
  • Multiple sclerosis and neuromyelitis optica spectrum disorders in Argentina: comparing baseline data from the Argentinean MS Registry (RelevarEM) 
    Rojas, Juan Ignacio; Alonso Serena, Marina; Garcea, Orlando; Patrucco, Liliana; Carrá, Adriana; Correale, Jorge; Vrech, Carlos; Pappolla, Agustín; Miguez, Jimena; Doldan, María L.; Silveira, Facundo; Alonso, Ricardo; Cohen, Leila; Pita, Cecilia; Silva, Berenice Anabel; Fiol, Marcela Paula; Gaitán, María Inés; Marrodán, Mariano; Negrotto, Laura; Ysrraelit, María Célica; RelevarEM investigators (Springer-Verlag, 2020-06)
    The objective of this study was to describe and compare the baseline epidemiological data of multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) patients included in RelevarEM (Clinical Trials registry ...
  • Multiple sclerosis and obesity: The role of adipokines 
    Correale, Jorge; Marrodán, Mariano (Frontiers Research Foundation, 2022-11-15)
    Multiple Sclerosis (MS), a chronic inflammatory disease of the central nervous system that leads to demyelination and neurodegeneration has been associated with various environmental and lifestyle factors. Population-based ...
  • Multiple sclerosis care units in Latin America: Consensus recommendations about its objectives and functioning implementation 
    Cristiano, Edgardo; Abad, Patricio; Becker, Jefferson; Carrá, Adriana; Correale, Jorge; Flores, José; Fruns, Manuel; Garcea, Orlando; Garcia Bónitto, Juan; Gracia, Fernando; Hamuy, Fernando; Navas, Carlos; Patrucco, Liliana; Rivera, Víctor M.; Velazquez, Merced; Rojas, Juan Ignacio (Elsevier, 2021-10-15)
    Objective Currently, there are several reasons to promote worldwide the concept of multiple sclerosis care units (MSCU) for a better management of affected patients. Ideally, the MSCU should have some human and technical ...
  • Multiple Sclerosis Misdiagnosis: A Persistent Problem to Solve 
    Gaitán, María Inés; Correale, Jorge (Frontiers Research Foundation, 2019-05-07)
  • Multiple sclerosis progression: time for a new mechanism-driven framework 
    Kuhlmann, Tanja; Moccia, Marcello; Coetzee, Timothy; Cohen, Jeffrey A.; Graves, Jennifer; Marrie, Ruth Ann; Montalban, Xavier; Yong, V. Wee; Thompson, Alan J.; Reich, Daniel S.; Correale, Jorge; International Advisory Committee on Clinical Trials in Multiple Sclerosis (Lancet Pub. Group, 2022-11-18)
    Traditionally, multiple sclerosis has been categorised by distinct clinical descriptors-relapsing-remitting, secondary progressive, and primary progressive-for patient care, research, and regulatory approval of medications. ...
  • Neuromyelitis optica spectrum disorders: from pathophysiology to therapeutic strategies 
    Carnero Contentti, Edgar; Correale, Jorge (BioMed Central, 2021-09-16)
    Neuromyelitis optica (NMO) is a chronic inflammatory autoimmune disease of the central nervous system (CNS) characterized by acute optic neuritis (ON) and transverse myelitis (TM). NMO is caused by a pathogenic serum IgG ...
  • Obesity and the risk of Multiple Sclerosis. The role of Leptin 
    Marrodán, Mariano; Farez, Mauricio Franco; Balbuena Aguirre, María Eugenia; Correale, Jorge (Wiley Periodicals, 2021-02)
    Objective: To investigate the effects of leptin on different T-cell populations, in order to gain more insight into the link between leptin and obesity. Methods: Three hundred and nine RRMS patients and 322 controls ...
  • Occurrence of area postrema syndrome during follow-up: phenotype and influence over NMOSD activity in LATAM in real-world settings. 
    Pestchanker, Claudia; Bertado Cortez, Brenda; Lana Peixoto, Marco A.; Gortari, José Ignacio; Castro Suarez, Sheila; Caparo Zamalloa, César; Galiana, Graciana; Peñalver, Francisco; Daccach Marques, Vanesa; Messias, Katharina; Galleguillos, Lorna; García, Fernando; Rojas, Juan I.; Patrucco, Liliana; Cristiano, Edgardo; Tkachuk, Verónica; Liwacki, Susana; Correale, Jorge; Marrodan, Mariano; Ysraelit, María Célica; Vrech, Carlos; Deri, Norma; Leguizamon, Felisa; Tavolini, Darío; Mainella, Carolina; Zanga, Gisela; Alonso Serena, Marina; Ciampi, Ethel; Herval Ribeiro Soares Neto, Herval; López, Pablo; Carnero Contentti, Edgar (Springer-Verlag, 2024-03-17)
    Introduction: We aimed to assess the frequency, duration, and severity of area postrema syndrome (APS) during follow-up in neuromyelitis optica spectrum disorder (NMOSD) patients, as well as its association with inflammatory ...
  • Ofatumumab versus Teriflunomide in Multiple Sclerosis 
    Hauser, Stephen L.; Bar-Or, Amit; Comi, Giancarlo; Correale, Jorge; Coyle, Patricia K.; Cross, Anne H.; de Seze, Jerome; Leppert, David; Montalban, Xavier; Selmaj, Krzysztof; Wiendl, Heinz; Kerloeguen, Cecile; Willi, Roman; Li, Bingbing; Kakarieka, Algirdas; Tomic, Davorka; Goodyear, Alexandra; Pingili, Ratnakar; ASCLEPIOS I and ASCLEPIOS II Trial Groups (Massachusetts Medical Society, 2020-08-06)
    Background: Ofatumumab, a subcutaneous anti-CD20 monoclonal antibody, selectively depletes B cells. Teriflunomide, an oral inhibitor of pyrimidine synthesis, reduces T-cell and B-cell activation. The relative effects of ...
  • Ontogenetic Oligodendrocyte Maturation Through Gestational Iron Deprivation: The Road Not Taken 
    Guitart, María Eugenia; Vence, Marianela; Correale, Jorge; Pasquini, Juana María; Rosato-Siri, María Victoria (Wiley, 2019-06-04)
    Developmental iron deficiency (dID) models facilitate the study of specific oligodendrocyte (OL) requirements for their progression to a mature state and subsequent contribution to myelination. In the current work, we used ...
  • Palmar pustular psoriasis associated with teriflunomide treatment 
    Negrotto, Laura; Correale, Jorge (Elsevier, 2019-01)
    Background Cutaneous adverse effects of Teriflunomide have been rarely reported. Objective and methods We report a relapsing remitting multiple sclerosis patient that developed palmar pustular psoriasis within one ...

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