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Browsing Enfermedades Desmielinizantes.artículos by Title

Browsing Enfermedades Desmielinizantes.artículos by Title

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  • Neuromyelitis optica spectrum disorders: from pathophysiology to therapeutic strategies 
    Carnero Contentti, Edgar; Correale, Jorge (BioMed Central, 2021-09-16)
    Neuromyelitis optica (NMO) is a chronic inflammatory autoimmune disease of the central nervous system (CNS) characterized by acute optic neuritis (ON) and transverse myelitis (TM). NMO is caused by a pathogenic serum IgG ...
  • New potential ligand-receptor axis involved in tissue repair as therapeutic targets in progressive multiple sclerosis 
    Carrera Silva, Eugenio Antonio; Correale, Jorge; Rothlin, Carla V.; Ortiz Wilczyñski, Juan Manuel (American Society for Pharmacology and Experimental Therapeutics, 2024-10-08)
    Progressive multiple sclerosis (PMS) represents the worsening phase of the disease by accumulative neurodegeneration and disability, mainly refractory to current treatments. The therapeutic options remain challenging based ...
  • Obesity and the risk of Multiple Sclerosis. The role of Leptin 
    Marrodán, Mariano; Farez, Mauricio Franco; Balbuena Aguirre, María Eugenia; Correale, Jorge (Wiley Periodicals, 2021-02)
    Objective: To investigate the effects of leptin on different T-cell populations, in order to gain more insight into the link between leptin and obesity. Methods: Three hundred and nine RRMS patients and 322 controls ...
  • Occurrence of area postrema syndrome during follow-up: phenotype and influence over NMOSD activity in LATAM in real-world settings. 
    Pestchanker, Claudia; Bertado Cortez, Brenda; Lana Peixoto, Marco A.; Gortari, José Ignacio; Castro Suarez, Sheila; Caparo Zamalloa, César; Galiana, Graciana Lourdes; Peñalver, Francisco; Daccach Marques, Vanessa; Messias, Katharina; Galleguillos Goiry, Lorna; García, Fernando; Rojas, Juan Ignacio; Patrucco, Liliana; Cristiano, Edgardo; Tkachuk, Verónica A.; Liwacki, Susana; Correale, Jorge; Marrodán, Mariano; Ysrraelit, María Célica; Vrech, Carlos; Deri, Norma; Leguizamon, Felisa; Tavolini, Darío; Mainella, Carolina; Zanga, Gisela; Alonso Serena, Marina; Ciampi, Ethel; Herval Ribeiro Soares Neto, Herval; López, Pablo Adrián; Carnero Contentti, Edgar (Springer-Verlag, 2024-03-17)
    Introduction: We aimed to assess the frequency, duration, and severity of area postrema syndrome (APS) during follow-up in neuromyelitis optica spectrum disorder (NMOSD) patients, as well as its association with inflammatory ...
  • Ofatumumab versus Teriflunomide in Multiple Sclerosis 
    Hauser, Stephen L.; Bar-Or, Amit; Comi, Giancarlo; Correale, Jorge; Coyle, Patricia K.; Cross, Anne H.; de Seze, Jerome; Leppert, David; Montalban, Xavier; Selmaj, Krzysztof; Wiendl, Heinz; Kerloeguen, Cecile; Willi, Roman; Li, Bingbing; Kakarieka, Algirdas; Tomic, Davorka; Goodyear, Alexandra; Pingili, Ratnakar; ASCLEPIOS I and ASCLEPIOS II Trial Groups (Massachusetts Medical Society, 2020-08-06)
    Background: Ofatumumab, a subcutaneous anti-CD20 monoclonal antibody, selectively depletes B cells. Teriflunomide, an oral inhibitor of pyrimidine synthesis, reduces T-cell and B-cell activation. The relative effects of ...
  • Ontogenetic Oligodendrocyte Maturation Through Gestational Iron Deprivation: The Road Not Taken 
    Guitart, María Eugenia; Vence, Marianela; Correale, Jorge; Pasquini, Juana María; Rosato-Siri, María Victoria (Wiley, 2019-06-04)
    Developmental iron deficiency (dID) models facilitate the study of specific oligodendrocyte (OL) requirements for their progression to a mature state and subsequent contribution to myelination. In the current work, we used ...
  • Palmar pustular psoriasis associated with teriflunomide treatment 
    Negrotto, Laura; Correale, Jorge (Elsevier, 2019-01)
    Background Cutaneous adverse effects of Teriflunomide have been rarely reported. Objective and methods We report a relapsing remitting multiple sclerosis patient that developed palmar pustular psoriasis within one ...
  • Paramagnetic Rim Lesions and Development of Clinical MS in Radiologically Isolated Syndrome 
    Lim, Timothy Reynold; Suthiphosuwan, Suradech; Gaitán, María Inés; Marrodán, Mariano; Horwath, Elizabeth A.; Guenette, Melanie; Bharatha, Aditya; Sati, Pascal; Absinta, Martina; Correale, Jorge; Shinohara, Russell; Reich, Daniel S.; Oh, Jiwon (American Medical Association, 2026-03)
    Importance: Most people with radiologically isolated syndrome (RIS) have high proportions of white matter lesions (WMLs) demonstrating the central vein sign (ie, central vein sign-positive lesion [CVS+L]) and at least 1 ...
  • Performance of McDonald 2017 multiple sclerosis diagnostic criteria and evaluation of genetic ancestry in patients with a first demyelinating event in Argentina 
    Marrodán, Mariano; Piedrabuena, María Agustina; Gaitán, María Inés; Fiol, Marcela Paula; Ysrraelit, María Célica; Carnero Contentti, Edgar; López, Pablo Adrián; Peuchot, Verónica; Correale, Jorge (Sage, 2023-03-21)
    Background: Information on performance of multiple sclerosis (MS) diagnostic criteria is scarce for populations from Latin America, Asia, or the Caribbean. Objective: To assess performance of revised 2017 McDonald ...
  • Performance of treatment response scoring systems among patients with multiple sclerosis treated with high-efficacy therapies 
    Marrodán, Mariano; Sao Avilés, Augusto; Río, Jordi; Cobo-Calvo, Álvaro; Fernández, Victoria; Pappolla, Agustin; Castilló, Joaquín; Vidal-Jordana, Ángela; Arrambide, Georgina; Tur, Carmen; Rodríguez-Acevedo, Breogán; Zabalza, Ana; Mongay-Ochoa, Neus; Vilaseca, Andreu; Rodriguez, Marta; Galán, Ingrid; Comabella, Manuel; Sastre-Garriga, Jaume; Tintoré, Mar; Auger, Cristina (Sage, 2025-02-10)
    Background: Predicting treatment response and disease progression in multiple sclerosis (MS) is challenging. Treatment Response Scoring Systems (TRSS) are potentially useful, but their utility in patients receiving ...
  • Plasma levels of an N-terminal tau fragment predict Alzheimer's and neurodegenerative disease biomarkers in autosomal dominant Alzheimer's disease 
    Schultz, Stephanie A.; Rao, Rao; Liu, Lei; Ostaszewski, Beth; Anderson, Amirah K.; Yau, Wai-Ying Wendy; Shirzadi, Zahra; Gordon, Brian A.; Hassenstab, Jason; Morris, John C.; Perrin, Richard J.; Allegri, Ricardo Francisco; Barthélemy, Nicolas R.; Fox, Nick C.; Day, Gregory S.; Jucker, Mathias; Levey, Allan I.; Levin, Johannes; Mori, Hiroshi; Salloway, Stephen (Wiley, 2026-06)
    Introduction: Tau species lacking truncation of the N-terminal region, including plasma N-terminal tau fragment 1 (NT1), have been previously associated with cognitive decline, neurodegeneration, and tau pathology in ...
  • Practice guideline update summary: Vaccine-preventable infections and immunization in multiple sclerosis: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology 
    Farez, Mauricio Franco; Correale, Jorge; Armstrong, Melissa J.; Rae-Grant, Alexander; Gloss, David; Donley, Diane; Holler-Managan, Yolanda; Kachuck, Norman J.; Jeffery, Douglas; Beilman, Maureen; Michelson, David; Lee, Erin; Cox, Julie; Getchius, Tom; Sejvar, James; Narayanaswami, Pushpa; Gronseth, Gary (Lippincott Williams & Wilkins, 2019-08-28)
    OBJECTIVE: To update the 2002 American Academy of Neurology (AAN) guideline regarding immunization and multiple sclerosis (MS). METHODS: The panel performed a systematic review and classified articles using the AAN ...
  • Prevalence of C9orf72 hexanucleotide repeat expansion in Greek patients with sporadic ALS 
    Sokratous, Maria; Schottlaender, Lucía V.; Bourinaris, Thomas; Marogianni, Chrysoula; Arnaoutoglou, Marianthi; Patrikiou, Eleni; Ralli, Styliani; Markou, Aikaterini; Dardiotis, Efthimios; Houlden, Henry; Hadjigeorgiou, Georgios M.; Xiromerisiou, Georgia (Taylor & Francis, 2020-07)
    A total of 178 consecutive patients with definite sALS without frontotemporal dementia (FTD) were enrolled in this study, after complete clinical evaluation. A Repeat-Primed Polymerase Chain Reaction (RP-PCR) protocol was ...
  • Prognostic Factors for Multiple Sclerosis Symptoms in Radiologically Isolated Syndrome 
    Fissolo, Nicolás; Schaedelin, Sabine; Villar, Luisa M.; Lünemann, Jan D.; Correale, Jorge; Rejdak, Konrad; Schwab, Nicholas; Vilaseca, Andreu; Held, Friederike; García-Merino, Antonio; Bittner, Stefan; Trojano, María; Furlan, Roberto; Tumani, Hayrettin; Pérez-Miralles, Francisco; Rosenstein, Igal; Galimberti, Daniela; Álvarez-Bravo, Gary; Thouvenot, Eric; Llufriu, Sara (American Medical Associatio, 2025-07-01)
    Importance: Understanding the risk factors for symptom development will allow clinicians to stratify people with radiologically isolated syndrome (pwRIS) more effectively and tailor their management strategies accordingl ...
  • Radiologically isolated syndrome: from biological bases to practical management 
    Barboza, Andrés G.; Carnero Contentti, Edgar; Curbelo, María Celeste; Halfon, Mario Javier; Rojas, Juan Ignacio; Silva, Berenice Anabel; Sinay, Vladimiro; Tizio, Santiago; Ysrraelit, María Célica; Alonso, Ricardo (Springer, 2021-01-25)
    Background: Technological advances and greater availability of magnetic resonance imaging have prompted an increment on incidental and unexpected findings within the central nervous system. The concept of radiologically ...
  • Real-World Effectiveness and Safety of Cladribine in Multiple Sclerosis: Longitudinal Data From the Nationwide Registry in Argentina 
    Rojas, Juan Ignacio; Alonso, Ricardo; Luetic, Geraldine G.; Patrucco, Liliana; Casas, Magdalena; Silva, Berenice Anabel; Miguez, Jimena; Deri, Norma; Vrech, Carlos; Liwacki, Susana; Piedrabuena, Raúl; Silva, Emanuel; Tkachuk, Verónica A.; Burgos, Marcos; Tavolini, Darío; Zanga, Gisela; Alvez Pinheiro, Amelia; Hryb, Javier Pablo; Leguizamon, Felisa; Knorre, Eduardo; López, Pablo Adrián; Martínez, Alejandra Diana; Carrá, Adriana; Alonso Serena, Marina; Cristiano, Edgardo; Correale, Jorge; Garcea, Orlando; Fernández Liguori, Nora; Carnero Contentti, Edgar (Lippincott Williams & Wilkins, 2024-05-23)
    Objective: The aim was to evaluate patient profiles, effectiveness and safety of cladribine (CLAD) in patients with relapsing-remitting multiple sclerosis in Argentina. Methods: This was a substudy included in RelevarEM ...
  • Real-world effectiveness of natalizumab treatment in patients with relapsing multiple sclerosis in Argentina and Chile 
    Ysrraelit, María Célica; Caride, Alejandro; Sinay, Vladimiro; Rivera Kindel, Mario; Halfon, Mario Javier; Patrucco, Liliana; Piedrabuena, Raúl; Diaz Aragunde, Vanina Eleonor (Associacao Arquivos De Neuro-Psiquitria Dr Oswaldo Lange, 2021-05-01)
    Background: The real-world effectiveness of natalizumab in people with relapsing multiple sclerosis (PwRMS) in Argentina and Chile has not been reported. Objective: To evaluate the effectiveness of natalizumab treatment ...
  • Rebound activity after fingolimod cessation: A case - control study 
    Barboza, Andrés G.; Gaitán, María Inés; Alonso, Ricardo; Ysrraelit, María Célica; Luetic, Geraldine G.; Liwacki, Susana; Patrucco, Liliana; Halfon, Mario Javier; Burgos, Marcos; Mainella, Carolina; Piedrabuena, Raúl; Recchia, Luciano; Steinberg, Judith; Tkachuk, Verónica A.; Zanga, Gisela; Carrá, Adriana; Chertcoff, Aníbal; Fernández Liguori, Nora; Lázaro, Luciana; Menichini, María Laura (Elsevier, 2022-02-09)
    Background: There has been an increase in the number of reports of multiple sclerosis (MS) rebound activity (RA), which is usually defined as a severe disease reactivation after natalizumab or fingolimod withdrawal that ...
  • Recognition memory in individuals with mild cognitive impairment and Alzheimer's dementia : a systematic review 
    Russo, María Julieta; Bueri, José; Ferrara, Lucía Alba; Labos, Edith; Sevlever, Gustavo Emilio; Allegri, Ricardo Francisco (Taylor & Francis, 2026-01-06)
    Background: Episodic memory impairment is a hallmark of Alzheimer's disease (AD) and is already present in its prodromal stage. While recall deficits are well established as predictors of memory performance, the role of ...
  • Remyelinating effect driven by transferrin-loaded extracellular vesicles 
    Mattera, Vanesa S.; Occhiuzzi, Federico; Correale, Jorge; Pasquini, Juana María (Wiley, 2023-10-20)
    Extracellular vesicles (EVs) are involved in diverse cellular functions, playing a significant role in cell-to-cell communication in both physiological conditions and pathological scenarios. Therefore, EVs represent a ...

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