Enfermedades Desmielinizantes.artículos: Envíos recientes

  • Editorial: Immunosuppressive Amino Acid Catabolizing Enzymes in Heallth and Disease 
    Castellano, Flavia; Correale, Jorge; Molinier-Frenkel, Valerie (Frontiers Research Foundation, 2021-05-05)
    Resumen no disponible
  • Combination therapy of apo-transferrin and thyroid hormones enhances remyelination 
    Rosato-Siri, María Victoria; Marziali, Leandro Nazareno; Mattera, Vanesa S.; Correale, Jorge; Pasquini, Juana María (Wiley-Liss, 2020-08-20)
    The current study presents two different approaches with a view to elucidating the interaction between thyroid hormones (TH) and apo-transferrin (aTf) and their role in myelination and remyelination. First, in vitro assays ...
  • GAS6 signaling tempers Th17 development in patients with multiple sclerosis and helminth infection 
    Ortiz Wilczyñski, Juan Manuel; Olexen, Cinthia M.; Errasti, Andrea E.; Schattner, Mirta; Rothlin, Carla V.; Correale, Jorge; Carrera Silva, Eugenio Antonio (Public Library of Science, 2020-11-21)
    Multiple sclerosis (MS) is a highly disabling neurodegenerative autoimmune condition in which an unbalanced immune response plays a critical role. Although the mechanisms remain poorly defined, helminth infections are known ...
  • Absence of latitudinal gradient in oligoclonal bands prevalence in Argentina 
    Negrotto, Laura; Marrodán, Mariano; Fiol, Marcela Paula; Gaitán, María Inés; Ysrraelit, María Célica; Vrech, Carlos; Pappolla, Agustín; Miguez, Jimena; Patrucco, Liliana; Cristiano, Edgardo; Rojas, Juan Ignacio; Carrá, Adriana; Chertcoff, Aníbal; Steinberg, Judith; Martinez, Alejandra D.; Curbelo, María Celeste; Cohen, Leila; Alonso, Ricardo; Garcea, Orlando; Correale, Jorge (Elsevier, 2020-11)
    Background: Like MS prevalence, oligoclonal bands (OCB) frequency seems to follow a latitudinal gradient. Argentina is extensive, latitude-wise, and previous studies have not found an MS prevalence latitudinal gradient. ...
  • Aspectos clínicos y demográficos de los pacientes con esclerosis múltiple secundaria progresiva en Argentina 
    Gaitán, María Inés; Marrodán, Mariano; Negrotto, Laura; Ysrraelit, María Célica; Miguez, Jimena; Alonso Serena, Marina; Pappolla, Agustín; Patrucco, Liliana; Cristiano, Edgardo; Vrech, Carlos; Rojas, Juan Ignacio; Grupo de Trabajo Relevar EM (Fundación Revista Medicina (Buenos Aires), 2020)
    El objetivo del estudio fue evaluar los aspectos clínicos y demográficos de los pacientes con esclerosis múltiple (EM) secundaria progresiva (EMSP) en los pacientes incluidos en el Registro Argentino de EM (RelevarEM, ...
  • Differential diagnosis in acute inflammatory myelitis 
    Marrodán, Mariano; Hernández, Micaela Anahí; Kohler, Alejandro Alfredo; Correale, Jorge (Elsevier, 2020-11)
    Introduction: Establishing differential diagnosis between different inflammatory causes of acute transverse myelitis (ATM) can be difficult. The objective of this study was to see which clinical, imaging or laboratory ...
  • Obesity and the risk of Multiple Sclerosis. The role of Leptin 
    Marrodán, Mariano; Farez, Mauricio Franco; Balbuena Aguirre, María Eugenia; Correale, Jorge (Wiley Periodicals, 2021-02)
    Objective: To investigate the effects of leptin on different T-cell populations, in order to gain more insight into the link between leptin and obesity. Methods: Three hundred and nine RRMS patients and 322 controls ...
  • Emerging drugs for the treatment of adult MOG-IgG-associated diseases 
    Carnero Contentti, Edgar; Marrodán, Mariano; Correale, Jorge (Taylor & Francis, 2021-04-16)
    Resumen no disponible
  • Ofatumumab versus Teriflunomide in Multiple Sclerosis 
    Hauser, Stephen L.; Bar-Or, Amit; Comi, Giancarlo; Correale, Jorge; Coyle, Patricia K.; Cross, Anne H.; de Seze, Jerome; Leppert, David; Montalban, Xavier; Selmaj, Krzysztof; Wiendl, Heinz; Kerloeguen, Cecile; Willi, Roman; Li, Bingbing; Kakarieka, Algirdas; Tomic, Davorka; Goodyear, Alexandra; Pingili, Ratnakar; ASCLEPIOS I and ASCLEPIOS II Trial Groups (Massachusetts Medical Society, 2020-08-06)
    Background: Ofatumumab, a subcutaneous anti-CD20 monoclonal antibody, selectively depletes B cells. Teriflunomide, an oral inhibitor of pyrimidine synthesis, reduces T-cell and B-cell activation. The relative effects of ...
  • COVID-19 in multiple sclerosis and neuromyelitis optica spectrum disorder patients in Latin America: COVID-19 in MS and NMOSD patients in LATAM 
    Alonso, Ricardo; Silva, Berenice Anabel; Garcea, Orlando; Correa Díaz, Edgar Patricio; Rodrigues Dos Passos, Giordani; Ramirez Navarro, Deyanira A.; Garcia Valle, Luis A.; Rodriguez Salinas, Luis C.; Negrotto, Laura; Luetic, Geraldine G.; Tkachuk, Verónica A.; Míguez, Jimena S.; Hamuy, Fernando; Goiry, Lorna Galleguillos; Ramírez Sánchez, Nicia E.; Burgos, Marcos; Steinberg, Judith; Balbuena Aguirre, María Eugenia; Monterrey Alvarez, Priscilla; Ysrraelit, María Célica (Elsevier, 2021-03-07)
    Background: There is no data regarding COVID-19 in Multiple Sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) patients in Latin America. Objective: The objective of this study was to describe the clinical ...
  • Iron Metabolism in Oligodendrocytes and Astrocytes, Implications for Myelination and Remyelination 
    Cheli, Veronica Teresita; Correale, Jorge; Paez, Pablo M.; Pasquini, Juana María (Sage, 2020-01)
    Iron is a key nutrient for normal central nervous system (CNS) development and function; thus, iron deficiency as well as iron excess may result in harmful effects in the CNS. Oligodendrocytes and astrocytes are crucial ...
  • Spinal cord and brain MRI should be routinely performed during follow-up in patients with NMOSD - Yes 
    Carnero Contentti, Edgar; Correale, Jorge (Sage, 2021-01)
  • Latin American consensus recommendations for management and treatment of neuromyelitis optica spectrum disorders in clinical practice 
    Carnero Contentti, Edgar; Rojas, Juan Ignacio; Cristiano, Edgardo; Daccach Marques, Vanessa; Flores, José; Lana Peixoto, Marco A.; Navas, Carlos; Papais Alvarenga, Regina; Sato, Douglas K.; Soto de Castillo, Ibis; Correale, Jorge (Elsevier, 2020-10)
    Background: During the last two decades, neuromyelitis optica spectrum disorder (NMOSD) has undergone important changes, with new diagnostic markers and criteria, better recognition of clinical phenotypes, better disease ...
  • Bruton's tyrosine kinase inhibitors: a promising emerging treatment option for multiple sclerosis 
    Carnero Contentti, Edgar; Correale, Jorge (Taylor & Francis, 2020-12)
  • Usage trend of oral drugs for multiple sclerosis patients in Argentina 
    Alonso, Ricardo; Garcea, Orlando; Eizaguirre, María Barbara; Man, Federico; Lopez Bizzo, Abril; Cohen, Leila; Rojas, Juan Ignacio; Patrucco, Liliana; Cristiano, Edgardo; Pita, Cecilia; Tkachuk, Verónica A.; Balbuena Aguirre, María Eugenia; Carnero Contentti, Edgar; López, Pablo Adrián; Pettinicchi, Juan Pablo; Deri, Norma; Miguez, Jimena; Pappolla, Agustín; Lázaro, Luciana; Fernández Liguori, Nora; Correale, Jorge; Carrá, Adriana; Silva, Berenice Anabel (Elsevier, 2020-12-02)
    Introduction: Over the past decade, numerous disease modifying drugs (DMDs) for relapsing- remitting multiple sclerosis (RRMS) have been approved in Argentina. The use of oral DMDs (oDMDs) has increased in recent years, ...
  • Immunosuppressive Amino-Acid Catabolizing Enzymes in Multiple Sclerosis 
    Correale, Jorge (Frontiers Research Foundation, 2021-01-20)
    Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease that affects the central nervous system. Although the pathogenesis of MS is not yet fully elucidated, several evidences suggest that autoimmune processes ...
  • Prevalence of C9orf72 hexanucleotide repeat expansion in Greek patients with sporadic ALS 
    Sokratous, Maria; Schottlaender, Lucía V.; Bourinaris, Thomas; Marogianni, Chrysoula; Arnaoutoglou, Marianthi; Patrikiou, Eleni; Ralli, Styliani; Markou, Aikaterini; Dardiotis, Efthimios; Houlden, Henry; Hadjigeorgiou, Georgios M.; Xiromerisiou, Georgia (Taylor & Francis, 2020-07)
    A total of 178 consecutive patients with definite sALS without frontotemporal dementia (FTD) were enrolled in this study, after complete clinical evaluation. A Repeat-Primed Polymerase Chain Reaction (RP-PCR) protocol was ...
  • Radiologically isolated syndrome: from biological bases to practical management 
    Barboza, Andrés G.; Carnero Contentti, Edgar; Curbelo, María Celeste; Halfon, Mario Javier; Rojas, Juan Ignacio; Silva, Berenice Anabel; Sinay, Vladimiro; Tizio, Santiago; Ysrraelit, María Célica; Alonso, Ricardo (Springer, 2021-01-25)
    Background: Technological advances and greater availability of magnetic resonance imaging have prompted an increment on incidental and unexpected findings within the central nervous system. The concept of radiologically ...
  • What percentage of AQP4-ab-negative NMOSD patients are MOG-ab positive? A study from the Argentinean multiple sclerosis registry (RelevarEM) 
    Carnero Contentti, Edgar; López, Pablo Adrián; Pettinicchi, Juan Pablo; Pappolla, Agustín; Miguez, Jimena; Patrucco, Liliana; Cristiano, Edgardo; Vrech, Carlos; Tkachuk, Verónica A.; Liwacki, Susana; Correale, Jorge; Marrodán, Mariano; Gaitán, María Inés; Fiol, Marcela Paula; Negrotto, Laura; Ysrraelit, María Célica; Burgos, Marcos; Leguizamon, Felisa; Tavolini, Darío; Deri, Norma (Elsevier, 2021-01-07)
    Background Myelin oligodendrocyte glycoprotein antibodies (MOG-ab) have been described in aquaporin-4-antibodies(AQP4-ab)-negative neuromyelitis optica spectrum disorder (NMOSD) patients. We aimed to evaluate the percentage ...
  • Vasculitic Peripheral Neuropathy, Differences Between Systemic and Non-Systemic Etiologies: A Case Series and Biopsy Report 
    Castiglione, Juan Ignacio; Marrodán, Mariano; Alessandro, Lucas; Taratuto, Ana Lía; Brand, Patricio; Nogués, Martín; Barroso, Fabio Adrián (IOS, 2021-01-01)
    Background:Vasculitic peripheral neuropathy (VPN) is caused by vessel inflammation leading to peripheral nerve injury of acute-to-subacute onset. When VPN occurs in the context of systemic disease it is classified as ...

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