Repositorio Institucional FLENI: Recent submissions

  • Involuntary moaning in a Hispanic family with eight affected members 
    Gisatulin, Maria; Rossi, Malco Damián; Perandones, Claudia; Klein, Christine; Lohmann, Katja; Merello, Marcelo (Elsevier, 2021-03-26)
    Involuntary moaning has been reported in sporadic cases of neurodegenerative diseases. A five-generation Hispanic family with eight members exhibiting involuntary moaning, most of whom with isolated moaning in the absence ...
  • The immune-checkpoint HLA-G/ILT4 is involved in the regulation of VEGF expression in clear cell renal cell carcinoma 
    García, Marcela N.; Palma, María Belén; Verine, Jerome; Miriuka, Santiago Gabriel; Inda, Ana María; Errecalde, Ana Lía; Desgrandchamps, François; Carosella, Edgardo D.; Tronik-Le Roux, Diana (BioMed Central, 2020-07-03)
    Background: Clear cell renal cell carcinoma (ccRCC), the most aggressive renal cancer, is characterized by early lymph node metastases and bad prognosis. Most therapies targeting advanced or metastatic ccRCC are based, as ...
  • Psychological distress associated with COVID-19 quarantine: Latent profile analysis, outcome prediction and mediation analysis 
    Fernández, Rodrigo Sebastián; Crivelli, Lucía; Magrath Guimet, Nahuel; Allegri, Ricardo Francisco; Pedreira, María Eugenia (Elsevier, 2020-12-01)
    Background: Mental health of the population during COVID-19 quarantine could be at risk. Previous studies in short quarantines, found mood-related and anxiety symptomatology. Here we aimed to characterize the subtypes of ...
  • Fading of Deep Brain Stimulation Efficacy Versus Disease Progression: Untangling a Gordian Knot 
    Fasano, Alfonso; Merello, Marcelo (Wiley, 2020-09-21)
  • COVID-19 pneumonia accurately detected on chest radiographs with artificial intelligence 
    Dorr, Francisco; Chaves, Hernán; Serra, María Mercedes; Ramirez, Andrés; Costa, Martín Elías; Seia, Joaquín; Cejas, Claudia Patricia; Castro, Marcelo; Eyheremendy, Eduardo; Fernández Slezak, Diego; Farez, Mauricio Franco; Study Collaborators (Elsevier, 2020-12)
    Purpose: To investigate the diagnostic performance of an Artificial Intelligence (AI) system for detection of COVID-19 in chest radiographs (CXR), and compare results to those of physicians working alone, or with AI ...
  • Insular functional alterations in emotional processing of schizophrenia patients revealed by Multivariate Pattern Analysis fMRI 
    Drucaroff, Lucas Javier; Fazzito, María Lucía; Castro, Mariana Nair; Nemeroff, Charles B.; Guinjoan, Salvador Martín; Villarreal, Mirta Fabiana (Pergamon Press, 2020-11)
    Emotion perception is impaired in schizophrenia patients (SP) and related to reduced social skills performance. There is a remarkable variability across subjects for functional neuroimaging alterations related to this ...
  • Comparing cortical signatures of atrophy between late-onset and autosomal dominant Alzheimer disease 
    Allegri, Ricardo Francisco; Dincer, Aylin; Gordon, Brian A.; Hari-Raj, Amrita; Keefe, Sarah J.; Flores, Shaney; McKay, Nicole S.; Paulick, Angela M.; Shady Lewis, Kristine E.; Feldman, Rebecca L.; Hornbeck, Russ C.; Ances, Beau M.; Berman, Sarah B.; Brickman, Adam M.; Brooks, William S.; Cash, David M.; Chhatwal, Jasmeer P.; Farlow, Martin R.; La Fougère, Christian; Fox, Nick C.; Fulham, Michael J.; Jack Jr, Clifford R.; Joseph-Mathurin, Nelly; Karch, Celeste M.; Lee, Athene; Levin, Johannes; Masters, Colin L.; McDade, Eric; Oh, Hwamee; Perrin, Richard J.; Raji, Cyrus; Salloway, Stephen; Schofield, Peter R.; Su, Yi; Villemagne, Victor L.; Wang, Qing; Weiner, Michael W.; Xiong, Chengjie; Yakushev, Igor; Morris, John C.; Bateman, Randall J.; Benzinger, Tammie L.S.; Dominantly Inherited Alzheimer Network (Elsevier, 2020-11-05)
    Defining a signature of cortical regions of interest preferentially affected by Alzheimer disease (AD) pathology may offer improved sensitivity to early AD compared to hippocampal volume or mesial temporal lobe alone. Since ...
  • Impact of Social Isolation on People with Dementia and Their Family Caregivers 
    Dos Santos Azevedo, Lílian Viana; Calandri, Ismael Luis; Slachevsky, Andrea; Graviotto, Héctor Gastón; Santos Vieira, Maria Carolina; Bezerra de Andrade, Caíssa; Peredo Rossetti, Adriana; Barroso Generoso, Alana; Carvalho Carmona, Karoline; Aparecida Cardoso Pinto, Ludmilla; Sorbara, Marcos; Pinto, Alejandra; Guajardo, Tania; Olavarría, Loreto; Thumala, Daniela; Crivelli, Lucía; Vivas, Ludmila; Allegri, Ricardo Francisco; Tonidandel Barbosa, Maira; Serrano, Cecilia M. (IOS, 2021-03-30)
    Background: People with dementia and their family caregivers may face a great burden through social isolation due to the COVID-19 pandemic, which can be manifested as various behavioral and clinical symptoms. Objective: ...
  • Living with dementia: increased level of caregiver stress in times of COVID-19 
    Cohen, Gabriela; Russo, María Julieta; Campos, Jorge; Allegri, Ricardo Francisco (Cambridge University Press, 2020-11)
    COVID-19 pandemic in Argentina has affected the care of older adults with dementia deeply. Our objective was to study how the obligatory social isolation affected stress caregiver and burden of care of family members of ...
  • Utility of a Spanish version of Three Words-Three Shapes Test to detect memory impairment in primary progressive aphasia 
    Calandri, Ismael Luis; Crivelli, Lucía; Morello García, Florentina; Allegri, Ricardo Francisco (Taylor & Frances, 2021-04-09)
    Introduction: Three Words-Three Shapes (3W3S) is a bedside test that assesses verbal and non-verbal memory and has proven useful in staging memory decline in amnestic disorders and primary progressive aphasia. Given its ...
  • Generation of a human induced pluripotent stem cell line from a familial Alzheimer's disease PSEN1 T119I patient 
    Isaja, Luciana; Rodríguez Varela, María Soledad; Marazita, Mariela Claudia; Mucci, Sofía; Itzcovich, Tatiana; Chrem Méndez, Patricio Alexis; Niikado, Matías; Ferriol Laffouillere, Sofía Luján; Allegri, Ricardo Francisco; Martinetto, Horacio; Sevlever, Gustavo Emilio; Scassa, María Élida; Surace, Ezequiel Ignacio; Romorini, Leonardo (Elsevier, 2021-04-05)
    Human induced pluripotent stem cells (hiPSC) line FLENIi001-A was reprogrammed from dermal fibroblasts using the lentiviral-hSTEMCCA-loxP vector. Fibroblasts were obtained from a skin biopsy of a 72-year-old Caucasian male ...
  • Global Impact of COVID-19 on Stroke Care and Intravenous Thrombolysis 
    Nogueira, Raul G.; Qureshi, Muhammad M.; Abdalkader, Mohamad; Ouriques Martins, Sheila C.; Yamagami, Hiroshi; Qiu, Zhongming; Yassin Mansour, Ossama; Sathya, Anvitha; Czlonkowska, Anna; Tsivgoulis, Georgios; Aguiar de Sousa, Diana; Demeestere, Jelle; Mikulik, Robert; Vanacker, Peter; Siegler, James E.; Kõrv, Janika; Biller, Jose; Liang, Conrad W.; Sangha, Navdeep S.; Pujol Lereis, Virginia Andrea (AAN, 2021-03-25)
    Objective: The objectives of this study were to measure the global impact of the pandemic on the volumes for intravenous thrombolysis (IVT), IVT transfers, and stroke hospitalizations over 4 months at the height of the ...
  • Correlation between 99mTc-TRODAT-1 SPECT and 18F-FDOPA PET in patients with Parkinson’s disease: a pilot study 
    Arena, Julieta E.; Urrutia, Leandro; Falasco, Germán; Ponce de León, Magdalena; Vázquez, Silvia; Rossi, Malco Damián; Merello, Marcelo (Colégio Brasileiro de Radiologia e Diagnóstico por Imagem, 2021-03-05)
    Objective: To determine whether technetium-99m-labeled tropane derivative single-photon emission computed tomography (99mTcTRODAT-1 SPECT) provides results comparable to those of the less widely available, less accessible ...
  • Abstract P80: Control of Vascular Risk Factors and Response to Stroke Symptoms During the Most Restrictive Period of the Covid-19 Quarantine. A Survey of Population Behavior in Argentina 
    Rodriguez Pérez, María Soledad; Rosales, Julieta Soledad; Dossi, Daiana Elizabeth; Ameriso, Sebastián Francisco (Lippincott Williams & Wilkins, 2021-03-11)
    Background and objectives: In preparation for the influx of Covid-19 patients and as a contagion prevention strategy, healthcare systems reduced or discontinued provision of ‘‘non-urgent’’ care. This policy could potentially ...
  • Abstract P84: Covid-19 and Stroke in the Latin American Stroke Registry (LASE) 
    Pujol Lereis, Virginia Andrea; Flores, Alan; Arauz-Gongora, Antonio; Abanto Argomedo, Carlos; Amaya, Pablo; Bayona, Hernán; Bonardo, Pablo; Diaz Escobar, Luis; Gomez Schneider, Maia Macarena; Góngora Rivera, Fernando; Lavados, Pablo M.; León, Carolina; Luraschi, Adriana; Márquez Romero, Juan Manuel; Martins, Sheila C.; Navia, Víctor Hugo; Ruiz Franco, Angélica; Vences, Miguel Ángel; Ameriso, Sebastián Francisco; LASE/COVID-19 Collaborators (Lippincott Williams & Wilkins, 2021-03-11)
    Background: Ischemic stroke has been reported to occur in approximately 5% of COVID-19 patients, although some reports are contradictory. Proposed mechanisms of this association are hypercoagulable state, vasculitis and ...
  • Abstract P385: Stroke-Related Hospital Admissions During Covid-19 Pandemic in the Latin American Stroke Registry (LASE) 
    Pujol Lereis, Virginia Andrea; Flores, Alan; Arauz-Gongora, Antonio; Abanto Argomedo, Carlos; Amaya, Pablo; Bayona, Hernán; Bonardo, Pablo; Diaz-Escobar, Luis; Gomez Schneider, Maia Macarena; Góngora Rivera, Fernando; Lavados, Pablo M.; León, Carolina; Luraschi, Adriana; Márquez Romero, Juan Manuel; Martins, Sheila C.; Navia, Víctor Hugo; Ruiz Franco, Angélica; Vences, Miguel Ángel; Ameriso, Sebastián Francisco; LASE/COVID-19 Collaborators (Lippincott Williams & Wilkins, 2021-03-11)
    Background: COVID-19 pandemic has forced important changes in health care worldwide. Stroke care networks have been affected, especially acute admissions and ancillary tests availability. We assessed the impact of the ...
  • COVID-19 Epidemic in Argentina: Worsening of Behavioral Symptoms in Elderly Subjects With Dementia Living in the Community 
    Cohen, Gabriela; Russo, María Julieta; Campos, Jorge; Allegri, Ricardo Francisco (Frontiers Research Foundation, 2020-08-28)
    In Argentina, the quality of care that elderly subjects with dementia living in the community received has been deeply affected by COVID-19 epidemic. Our objective was to study to what extend mandatory quarantine imposed ...
  • Utility of a Screening Test (MoCa) to Predict Amyloid Physiopathology in Mild Cognitive Impairment 
    Clarens, María Florencia; Calandri, Ismael Luis; Helou, María Belén; Martín, María Eugenia; Chrem Méndez, Patricio Alexis; Crivelli, Lucía (Universidad de la Costa, 2020-11-09)
    Introduction: The MoCa (Montreal Cognitive Assessment) Screening test has become relevant in recent years in the screening of patients with Mild Cognitive Impairment (MCI). It is important to seek and study simple and ...
  • Diagnostic accuracy of the UDS 3.0 neuropsychological battery in a cohort with Alzheimer's disease in Colombia 
    Porto, Maria F.; Benitez Agudelo, Juan Camilo; Aguirre Acevedo, Daniel Camilo; Barceló Martínez, Ernesto; Allegri, Ricardo Francisco (Taylor & Francis, 2021-03-24)
    Background: Alzheimer's disease (AD) is a neurodegenerative disease that causes a gradual loss of cognitive functions and limits daily activities performance. Early diagnosis of AD is essential to start timely treatment. ...
  • COVID-19 in multiple sclerosis and neuromyelitis optica spectrum disorder patients in Latin America: COVID-19 in MS and NMOSD patients in LATAM 
    Alonso, Ricardo; Silva, Berenice Anabel; Garcea, Orlando; Correa Díaz, Edgar Patricio; Rodrigues Dos Passos, Giordani; Ramirez Navarro, Deyanira A.; Garcia Valle, Luis A.; Rodriguez Salinas, Luis C.; Negrotto, Laura; Luetic, Geraldine G.; Tkachuk, Verónica A.; Míguez, Jimena S.; Hamuy, Fernando; Goiry, Lorna Galleguillos; Ramírez Sánchez, Nicia E.; Burgos, Marcos; Steinberg, Judith; Balbuena Aguirre, María Eugenia; Monterrey Alvarez, Priscilla; Ysrraelit, María Célica (Elsevier, 2021-03-07)
    Background: There is no data regarding COVID-19 in Multiple Sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) patients in Latin America. Objective: The objective of this study was to describe the clinical ...

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