Schultz, Stephanie A.; Allegri, Ricardo Francisco; Schultz, Aaron P.; Goate, Alison M.; Levey, Allan I.; Fagan, Anne M.; Hanseeuw, Bernard J.; Koeppe, Robert A.; Gordon, Brian A.; Cruchaga, Carlos; Karch, Celeste M.; Chen, Charles D.; Xiong, Chengjie; Jack Jr, Clifford R.; Fitzpatrick, Colleen D.; McDade, Eric; Chui, Helena C.; Mori, Hiroshi; Lee, Jae-Hong; Noble, James M.
(Wiley, 2022-12)
Background
Rates of cognitive and biomarker change in Autosomal Dominant Alzheimer disease (ADAD) vary substantially across individuals. Prior cross-sectional work suggests that the location of the pathogenic variant ...