Repositorio Dspace

Listar Neurología Cognitiva.artículos por autor "Schindler, Suzanne E."

Listar Neurología Cognitiva.artículos por autor "Schindler, Suzanne E."

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  • Association of Longitudinal Changes in Cerebrospinal Fluid Total Tau and Phosphorylated Tau 181 and Brain Atrophy With Disease Progression in Patients With Alzheimer Disease 
    Llibre Guerra, Jorge J.; Li, H; Schindler, Suzanne E.; Gordon, Brian A.; Fagan, Anne M.; Morris, John C.; Benzinger, Tammie L.S.; Hassenstab, Jason; Wang, Guoquiao; Allegri, Ricardo Francisco; Berman, Sarah B.; Chhatwal, Jasmeer P.; Farlow, Martin R.; Holtzman, David M.; Jucker, Mathias; Levin, Johannes; Noble, James M.; Salloway, Stephen; Schofield, Peter R.; Karch, Celeste M.; Fox, Nick C.; Xiong, Chengjie; Bateman, Randall J.; McDade, Eric (American Medical Association, 2019-12-02)
    The amyloid/tau/neurodegeneration (A/T/N) framework uses cerebrospinal fluid (CSF) levels of total tau (tTau) as a marker of neurodegeneration and CSF levels of phosphorylated tau 181 (pTau181) as a marker of tau tangles. ...
  • Cross-sectional and longitudinal comparisons of biomarkers and cognition among asymptomatic middle-aged individuals with a parental history of either autosomal dominant or late-onset Alzheimer's disease 
    Xiong, Chengjie; McCue, Lena M.; Buckles, Virginia; Grant, Elizabeth; Agboola, Folasade; Coble, Dean; Bateman, Randall J.; Fagan, Anne M.; Benzinger, Tammie L.S.; Hassenstab, Jason; Schindler, Suzanne E.; McDade, Eric; Moulder, Krista L.; Gordon, Brian A.; Cruchaga, Carlos; Day, Gregory S.; Ikeuchi, Takeshi; Suzuki, Kazushi; Allegri, Ricardo Francisco; Dominantly Inherited Alzheimer Network (Wiley, 2023-01-14)
    Background: Comparisons of late-onset Alzheimer's disease (LOAD) and autosomal dominant AD (ADAD) are confounded by age. Methods: We compared biomarkers from cerebrospinal fluid (CSF), magnetic resonance imaging, and ...
  • Longitudinal clinical, cognitive and biomarker profiles in dominantly inherited versus sporadic early-onset Alzheimer's disease 
    Llibre Guerra, Jorge J.; Iaccarino, Leonardo; Coble, Dean; Edwards, Lauren; Li, Yan; McDade, Eric; Strom, Amelia; Gordon, Brian; Mundada, Nidhi; Schindler, Suzanne E.; Tsoy, Elena; Ma, Yinjiao; Lu, Ruijin; Fagan, Anne M.; Benzinger, Tammie L. S.; Soleimani-Meigooni, David; Aschenbrenner, Andrew J.; Allegri, Ricardo Francisco; Patricio Alexis, Chrem Méndez; Surace, Ezequiel Ignacio (Oxford University Press, 2023-10-18)
    Approximately 5% of Alzheimer's disease cases have an early age at onset (<65 years), with 5-10% of these cases attributed to dominantly inherited mutations and the remainder considered as sporadic. The extent to which ...
  • Multimodal brain age estimates relate to Alzheimer disease biomarkers and cognition in early stages: a cross-sectional observational study 
    Millar, Peter R.; Gordon, Brian A.; Luckett, Patrick H.; Benzinger, Tammie L.S.; Cruchaga, Carlos; Fagan, Anne M.; Hassenstab, Jason; Perrin, Richard J.; Schindler, Suzanne E.; Allegri, Ricardo Francisco; Day, Gregory S.; Farlow, Martin R.; Mori, Hiroshi; Nübling, Georg; Dominantly Inherited Alzheimer Network; Bateman, Randall J.; Morris, John C.; Ances, Beau M. (eLife Sciences Publications, 2023-01-06)
    Background: Estimates of 'brain-predicted age' quantify apparent brain age compared to normative trajectories of neuroimaging features. The brain age gap (BAG) between predicted and chronological age is elevated in symptomatic ...
  • Predicting brain age from functional connectivity in symptomatic and preclinical Alzheimer disease 
    Millar, Peter R.; Luckett, Patrick H.; Gordon, Brian A.; Benzinger, Tammie L.S.; Schindler, Suzanne E.; Fagan, Anne M.; Cruchaga, Carlos; Bateman, Randall J.; Allegri, Ricardo Francisco; Jucker, Mathias; Lee, Jae-Hong; Mori, Hiroshi; Salloway, Stephen; Igor, Yakushev; Morris, John C.; Ances, Beau M.; Dominantly Inherited Alzheimer Network (Academic Press, 2022-08-01)
    "Brain-predicted age" quantifies apparent brain age compared to normative neuroimaging trajectories. Advanced brain-predicted age has been well established in symptomatic Alzheimer disease (AD), but is underexplored in ...

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