Generation of a gene-corrected human isogenic iPSC line from an Alzheimer's disease iPSC line carrying the PSEN1 H163R mutation

Hernández, Damián; Morgan Schlicht, Stephanie; Clarke, Jordan Elli; Daniszewski, Maciej; Karch, Celeste M.; Dominantly Inherited Alzheimer Network; Goate, Alison M.; Pébay, Alice; Allegri, Ricardo Francisco

dc.contributor.author	Hernández, Damián
dc.contributor.author	Morgan Schlicht, Stephanie
dc.contributor.author	Clarke, Jordan Elli
dc.contributor.author	Daniszewski, Maciej
dc.contributor.author	Karch, Celeste M.
dc.contributor.author	Dominantly Inherited Alzheimer Network
dc.contributor.author	Goate, Alison M.
dc.contributor.author	Pébay, Alice
dc.contributor.author	Allegri, Ricardo Francisco
dc.date.accessioned	2024-08-27T13:35:59Z
dc.date.available	2024-08-27T13:35:59Z
dc.date.issued	2024-09
dc.identifier.citation	Hernández D, Morgan Schlicht S, Elli Clarke J, Daniszewski M, Karch CM; Dominantly Inherited Alzheimer Network (DIAN); Goate AM, Pébay A. Generation of a gene-corrected human isogenic iPSC line from an Alzheimer's disease iPSC line carrying the PSEN1 H163R mutation. Stem Cell Res. 2024 Sep;79:103495. doi: 10.1016/j.scr.2024.103495. Epub 2024 Jul 29.	es_ES
dc.identifier.uri	https://doi.org/10.1016/j.scr.2024.103495
dc.identifier.uri	https://repositorio.fleni.org.ar/xmlui/handle/123456789/1198
dc.description.abstract	We report the generation of a gene-edited human induced pluripotent stem cell (iPSC) line from an Alzheimer's disease patient-derived iPSC line harbouring the PSEN1 H163R mutation. This line demonstrates pluripotent stem cell morphology, expression of pluripotency markers, and maintains a normal karyotype.	es_ES
dc.language.iso	eng	es_ES
dc.publisher	Elsevier	es_ES
dc.subject	Alzheimer Disease	es_ES
dc.subject	Enfermedad de Alzheimer	es_ES
dc.subject	Cell Differentiation	es_ES
dc.subject	Diferenciación Celular	es_ES
dc.subject	Mutation	es_ES
dc.subject	Mutación	es_ES
dc.subject	Induced Pluripotent Stem Cells	es_ES
dc.subject	Células Madre Pluripotentes Inducidas	es_ES
dc.subject	Biología Celular
dc.subject	Cell Biology
dc.subject	Stem Cells
dc.subject	Células Madre
dc.title	Generation of a gene-corrected human isogenic iPSC line from an Alzheimer's disease iPSC line carrying the PSEN1 H163R mutation	es_ES
dc.type	info:eu-repo/semantics/article	es_ES
dc.description.fil	Fil: Allegri, Ricardo Francisco. Fleni. Departamento de Neurología. Servicio de Neurología Cognitiva, Neuropsicología y Neuropsiquiatría; Argentina.
dc.relation.ispartofVOLUME	79
dc.relation.ispartofPAGINATION	103495
dc.relation.ispartofCOUNTRY	Inglaterra
dc.relation.ispartofCITY	Oxford
dc.relation.ispartofCITY	Oxford
dc.relation.ispartofTITLE	Stem cell research
dc.relation.ispartofISSN	1876-7753
dc.type.snrd	info:ar-repo/semantics/artículo	es_ES