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Browsing Neurología Cognitiva.artículos by Title

Browsing Neurología Cognitiva.artículos by Title

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  • Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer's disease 
    Johnson, Erik C. B.; Bian, Shijia; Haque, Rafi U.; Carter, E. Kathleen; Watson, Caroline M.; Gordon, Brian A.; Ping, Lingyan; Duong, Duc M.; Epstein, Michael P.; McDade, Eric; Barthélemy, Nicolas R.; Karch, Celeste M.; Xiong, Chengjie; Cruchaga, Carlos; Perrin, Richard J.; Wingo, Aliza P.; Dominantly Inherited Alzheimer Network (Nature Publishing Company, 2023-08-07)
    Alzheimer's disease (AD) pathology develops many years before the onset of cognitive symptoms. Two pathological processes-aggregation of the amyloid-β (Aβ) peptide into plaques and the microtubule protein tau into ...
  • Change in Cerebrospinal Fluid Tau Microtubule Binding Region Detects Symptom Onset, Cognitive Decline, Tangles, and Atrophy in Dominantly Inherited Alzheimer's Disease 
    Horie, Kanta; Li, Yan; Barthélemy, Nicolas R.; Gordon, Brian A.; Hassenstab, Jason; Benzinger, Tammie L.S.; Fagan, Anne M.; Morris, John C.; Karch, Celeste M.; Xiong, Chengjie; Allegri, Ricardo Francisco; Chrem Méndez, Patricio Alexis; Ikeuchi, Takeshi; Kasuga, Kensaku; Noble, James M.; Farlow, Martin R.; Chhatwal, Jasmeer P.; Day, Gregory S.; Schofield, Peter R.; Dominantly Inherited Alzheimer Network (Wiley, 2023-03-16)
    Objective: Identifying cerebrospinal fluid measures of the microtubule binding region of tau (MTBR-tau) species that reflect tau aggregation could provide fluid biomarkers that track Alzheimer's disease related neurofibrillary ...
  • Changes in cognitive functioning after COVID-19: A systematic review and meta-analysis 
    Crivelli, Lucía; Palmer, Katie; Calandri, Ismael Luis; Guekht, Alla; Beghi, Ettore; Carroll, William; Frontera, Jennifer; García-Azorín, David; Westenberg, Érica; Winkler, Andrea Sylvia; Mangialasche, Francesca; Allegri, Ricardo Francisco; Kivipelto, Miia (2022-05)
    Introduction: We conducted a systematic review and meta-analysis of the cognitive effects of coronavirus disease 2019 (COVID-19) in adults with no prior history of cognitive impairment. Methods: Searches in Medline/Web ...
  • Clinical and functional evidence supporting the pathogenicity of the novel PSEN1 p.R358P variant in early-onset Alzheimer's disease 
    García Chialva, Diego; Itzcovich, Tatiana; Cifarelli, Diego; Apecetche, Manuela; Chrem Méndez, Patricio; Magrath Guimet, Nahuel; Vázquez, Silvia; Bérgamo, Yanina; Allegri, Ricardo Francisco; Marazita, Mariela; Sevlever, Gustavo Emilio; Isaja, Luciana; Surace, Ezequiel Ignacio; Romorini, Leonardo (Sage, 2025-11-06)
    BackgroundPathogenic variants in PSEN1, PSEN2, or AβPP cause early-onset Alzheimer's disease (EOAD). Several novel variants remain of uncertain significance (VUS) due to limited evidence. The PSEN1 p.R358P variant has not ...
  • Clinical Manifestations 
    Clarens, María Florencia; Chrem Méndez, Patricio Alexis; Tapajóz Pereira de Sampaio, Fernanda; Martinez, Carlos; Helou, María Belén; Surace, Ezequiel Ignacio; Crivelli, Lucía; Romero, Daniela; Vigo, Gabriela; Allegri, Ricardo Francisco (Wiley, 2023-12-25)
    Background: In recent years, there has been an increase in the number of case reports of families with autosomal dominant Alzheimer's disease (ADAD) in Latin America (LA). Nevertheless, little is known about the clinical ...
  • Clinical Validation of the SECONDs Tool for Evaluating Disorders of Consciousness in Argentina 
    Russo, María Julieta; Sampayo, María de la Paz; Arias, Paula; García, Vanina; Gambero, Yanina; Maiarú, Mariano; Deschle, Florencia; Pavón, Hernán (MDPI, 2025-10-07)
    Background: The Coma Recovery Scale-Revised (CRS-R) is the gold standard for diagnosing chronic disorders of consciousness (DoC); however, its clinical utility is limited by lengthy administration and the need for specialized ...
  • Clinical, pathophysiological and genetic features of motor symptoms in autosomal dominant Alzheimer’s disease 
    Vöglein, Jonathan; Paumier, Katrina; Jucker, Mathias; Preische, Oliver; McDade, Eric; Hassenstab, Jason; Benzinger, Tammie L.S.; Noble, James M.; Berman, Sarah B.; Graff-Radford, Neill R.; Ghetti, Bernardino; Farlow, Martin R.; Chhatwal, Jasmeer P.; Salloway, Stephen; Xiong, Chengjie; Karch, Celeste M.; Cairns, Nigel; Mori, Hiroshi; Schofield, Peter R.; Masters, Colin L.; Goate, Alison M.; Buckles, Virginia; Fox, Nick C.; Rossor, Martin N.; Chrem Méndez, Patricio Alexis; Allegri, Ricardo Francisco; Ringman, John M.; Höglinger, Günter U.; Steiner, Harald; Dieterich, Marianne; Haass, Christian; Laske, Christoph; Morris, John C.; Bateman, Randall J.; Danek, Adrian; Levin, Johannes; Dominantly Inherited Alzheimer Network (Oxford, 2019-03-20)
    Owing to an early and marked deposition of amyloid-β in the basal ganglia, autosomal dominant Alzheimer’s disease could distinctly involve motor symptoms. Therefore, we aimed to assess the prevalence and characteristics ...
  • Cognitive and physical activities are associated with cognitive resilience in a memory clinic cohort 
    Bocancea, Diana I.; van Loenhoud, Anna C.; Kuijper, Bart; Calandri, Ismael Luis; Groot, Colin; Venkatraghavan, Vikram; de Boer, Casper; Ten Kate, Mara; Trieu, Calvin; Teunissen, Charlotte E.; van de Giessen, Elsmarieke; Leeuwis, Anna E.; Schlueter, Lisa-Marie; van Harten, Argonde C.; Pijnenburg, Yolande A. L.; Barkhof, Frederik; van der Flier, Wiesje M.; Ossenkoppele, Rik (Oxford University Press, 2025-09-06)
    Lifestyle factors such as participation in cognitively stimulating activities and physical activity are hypothesized to foster neural connections and enhance resilience, thereby attenuating cognitive loss in the context ...
  • Cognitive consequences of COVID-19: results of a cohort study from South America 
    Crivelli, Lucía; Calandri, Ismael Luis; Corvalán, Nicolás; Carello, María Agostina; Keller, Greta; Martínez Canyazo, Carlos; Arruabarrena, Micaela María; Allegri, Ricardo Francisco (Associacao Arquivos De Neuro-Psiquitria Dr Oswaldo Lange, 2021-10-11)
    Background: Neurological and psychiatric manifestations associated with SARS-CoV-2 infection have been reported throughout the scientific literature. However, studies on post-COVID cognitive impairment in people with no ...
  • Cognitive Rehabilitation Using Teleneuropsychology. A Cohort Study in South America 
    Martínez Canyazo, Carlos; Fernández, Rodrigo Sebastián; Helou, María Belén; Arruabarrena, Micaela María; Corvalán, Nicolás; Carello, María Agostina; Harris, Paula; Feldman, Mónica; Calandri, Ismael Luis; Martin, María Eugenia; Allegri, Ricardo Francisco; Crivelli, Lucía (Cambridge University Press, 2023-12-21)
    Objective: The COVID-19 pandemic has affected the continuity of cognitive rehabilitation (CR) worldwide. However, the use of teleneuropsychology (TNP) to provide CR has contributed significantly to the continuity of ...
  • Comparative accuracy of Mini-Linguistic State Examination, Addenbrooke's Cognitive Examination, and Depistage Cognitif de Quebec for the diagnosis of primary progressive aphasia 
    Fernández Romero, Lucía; Morello García, Florentina; Laforce Jr, Robert; Delgado Alonso, Cristina; Delgado Álvarez, Alfonso; Gil Moreno, María José; Lavoie, Monica; Cuetos, Fernando; Matias Guiu, Jordi A.; Matias Guiu, Jorge (SAGE, 2024-10-17)
    Background: Clinical diagnosis in primary progressive aphasia (PPA) is challenging. Recently, emphasis has been placed on the importance of screening evaluation. Three different screening tests that use different strategies ...
  • Comparative diagnostic performance of artificial intelligence models in structural MRI for schizophrenia: A systematic review and meta-analysis 
    Kotochinsky, Martin; Oliveira Fonseca, Pandora Eloa; Ramirez Lopera, Veronica; Mora, Laura; Wellgner Fernandes Oliveira, Amador; Cesar Teixeira Sirena, Eduardo; Bandeira de Melo Guimarães, Felipe; Lahitou Herlyn, Delfina; Norbu Sherpa, Nima; Gonzalez Lezana, Andrea; Pardini Fagundes, Thales (Elsevier, 2025-11-04)
    Introduction: Timely diagnosis of schizophrenia is essential to ensure prompt treatment initiation and adherence. Structural magnetic resonance imaging (sMRI), when combined with artificial intelligence (AI), offers a ...
  • Comparative neurofilament light chain trajectories in CSF and plasma in autosomal dominant Alzheimer's disease 
    Hofmann, Anna; Häsler, Lisa M.; Lambert, Marius; Kaeser, Stephan A.; Gräber-Sultan, Susanne; Obermüller, Ulrike; Kuder-Buletta, Elke; La Fougère, Christian; Laske, Christoph; Vöglein, Jonathan; Levin, Johannes; Fox, Nick C.; Ryan, Natalie S.; Zetterberg, Henrik; Llibre Guerra, Jorge J.; Perrin, Richard J.; Ibanez, Laura; Allegri, Ricardo Francisco; Chrem Méndez, Patricio Alexis; Dominantly Inherited Alzheimer Network (Nature Pub. Group, 2024)
    Disease-modifying therapies for Alzheimer's disease (AD) are likely to be most beneficial when initiated in the presymptomatic phase. To track the benefit of such interventions, fluid biomarkers are of great importance, ...
  • Comparing cortical signatures of atrophy between late-onset and autosomal dominant Alzheimer disease 
    Allegri, Ricardo Francisco; Dincer, Aylin; Gordon, Brian A.; Hari-Raj, Amrita; Keefe, Sarah J.; Flores, Shaney; McKay, Nicole S.; Paulick, Angela M.; Shady Lewis, Kristine E.; Feldman, Rebecca L.; Hornbeck, Russ C.; Ances, Beau M.; Berman, Sarah B.; Brickman, Adam M.; Brooks, William S.; Cash, David M.; Chhatwal, Jasmeer P.; Farlow, Martin R.; La Fougère, Christian; Fox, Nick C.; Fulham, Michael J.; Jack Jr, Clifford R.; Joseph-Mathurin, Nelly; Karch, Celeste M.; Lee, Athene; Levin, Johannes; Masters, Colin L.; McDade, Eric; Oh, Hwamee; Perrin, Richard J.; Raji, Cyrus; Salloway, Stephen; Schofield, Peter R.; Su, Yi; Villemagne, Victor L.; Wang, Qing; Weiner, Michael W.; Xiong, Chengjie; Yakushev, Igor; Morris, John C.; Bateman, Randall J.; Benzinger, Tammie L.S.; Dominantly Inherited Alzheimer Network (Elsevier, 2020-11-05)
    Defining a signature of cortical regions of interest preferentially affected by Alzheimer disease (AD) pathology may offer improved sensitivity to early AD compared to hippocampal volume or mesial temporal lobe alone. Since ...
  • Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study 
    Boerwinkle, Anna H.; Gordon, Brian A.; Wisch, Julie K.; Flores, Shaney; Henson, Rachel L.; Butt, Omar H.; McKay, Nicole S.; Chen, Charles D.; Benzinger, Tammie L.S.; Fagan, Anne M.; Handen, Benjamin L.; Christian, Bradley T.; Head, Elizabeth; Mapstone, Mark; Rafii, Michael S.; Alzheimer's Biomarker Consortium-Down Syndrome; Dominantly Inherited Alzheimer Network; Allegri, Ricardo Francisco; Chrem Méndez, Patricio Alexis; Egido, Noelia (Elsevier, 2022-12-12)
    Background: Important insights into the early pathogenesis of Alzheimer's disease can be provided by studies of autosomal dominant Alzheimer's disease and Down syndrome. However, it is unclear whether the timing and spatial ...
  • Comparison of CSF biomarkers in Down syndrome and autosomal dominant Alzheimer's disease: a cross-sectional study 
    Fagan, Anne M.; Henson, Rachel L.; Li, Yan; Boerwinkle, Anna H.; Xiong, Chengjie; Bateman, Randall J.; Goate, Alison M.; Ances, Beau M.; Doran, Eric; Christian, Bradley T.; Lai, Florence; Rosas, H. Diana; Schupf, Nicole; Krinsky-McHale, Sharon J.; Silverman, Wayne; Lee, Joseph H.; Klunk, William E.; Handen, Benjamin L.; Allegri, Ricardo Francisco; Alzheimer's Biomarker Consortium-Down Syndrome; Dominantly Inherited Alzheimer Network (Elsevier, 2021-08)
    Background Due to trisomy of chromosome 21 and the resultant extra copy of the amyloid precursor protein gene, nearly all adults with Down syndrome develop Alzheimer's disease pathology by the age of 40 years and are at ...
  • Comparison of tau spread in people with Down syndrome versus autosomal-dominant Alzheimer's disease: a cross-sectional study 
    Wisch, Julie K.; McKay, Nicole S.; Boerwinkle, Anna H.; Kennedy, James; Flores, Shaney; Handen, Benjamin L.; Christian, Bradley T.; Head, Elizabeth; Mapstone, Mark; Rafii, Michael S.; O'Bryant, Sid E.; Price, Julie C.; Laymon, Charles M.; Krinsky-McHale, Sharon J.; Lai, Florence; Alzheimer's Biomarker Consortium-Down Syndrome; Dominantly Inherited Alzheimer Network; Allegri, Ricardo Francisco; Chrem Méndez, Patricio Alexis; Surace, Ezequiel Ignacio (Lancet Pub. Group, 2024-05)
    Background: In people with genetic forms of Alzheimer's disease, such as in Down syndrome and autosomal-dominant Alzheimer's disease, pathological changes specific to Alzheimer's disease (ie, accumulation of amyloid and ...
  • Connectivity and Patterns of Regional Cerebral Blood Flow, Cerebral Glucose Uptake, and Aβ-Amyloid Deposition in Alzheimer's Disease (Early and Late-Onset) Compared to Normal Ageing 
    Falasco, Germán; Damián, Andrés; Urrutia, Leandro; Niell, Nicolás; Lago, Graciela; Bérgamo, Yanina; Chrem Méndez, Patricio Alexis; Quagliata, Adriana; Bentancourt, Cecilia; Calandri, Ismael Luis; Cordero, Ismael; Ponce de León, Magdalena; Contreras, Valeria; Feuerstein, Viviana; Dansilio, Sergio; Allegri, Ricardo Francisco; Engler, Henry; Vázquez, Silvia (Bentham Science Publishers, 2021-11-15)
    Purpose: The aim of this study was to investigate the differences in early (EOAD) and late (LOAD) onset of Alzheimer´s disease, as well as glucose uptake, regional cerebral blood flow (R1), amyloid depositions, and functional ...
  • Conocimiento sobre demencia en la población general, familiares, estudiantes y trabajadores de la salud en la Ciudad Autónoma de Buenos Aires 
    Gallo, María Fernanda; Tabernero, María Eugenia; Berrios, Waleska; Cores, Evangelina Valeria; Deschle, Florencia (Sociedad Neurológica Argentina, 2022-04)
    Resumen Conocer la presencia de ideas erróneas con relación a las demencias en distintas poblaciones permite llevar a cabo intervenciones tendientes a mejorar el acceso al conocimiento. Objetivo Evaluar el conocimiento ...
  • COVID-19 Epidemic in Argentina: Worsening of Behavioral Symptoms in Elderly Subjects With Dementia Living in the Community 
    Cohen, Gabriela; Russo, María Julieta; Campos, Jorge; Allegri, Ricardo Francisco (Frontiers Research Foundation, 2020-08-28)
    In Argentina, the quality of care that elderly subjects with dementia living in the community received has been deeply affected by COVID-19 epidemic. Our objective was to study to what extend mandatory quarantine imposed ...

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