Neurología Cognitiva.artículos: Recent submissions

  • Longitudinal clinical, cognitive and biomarker profiles in dominantly inherited versus sporadic early-onset Alzheimer's disease 
    Llibre Guerra, Jorge J.; Iaccarino, Leonardo; Coble, Dean; Edwards, Lauren; Li, Yan; McDade, Eric; Strom, Amelia; Gordon, Brian A.; Mundada, Nidhi; Schindler, Suzanne E.; Tsoy, Elena; Ma, Yinjiao; Lu, Ruijin; Fagan, Anne M.; Benzinger, Tammie L.S.; Soleimani Meigooni, David; Aschenbrenner, Andrew J.; Allegri, Ricardo Francisco; Patricio Alexis, Chrem Méndez; Surace, Ezequiel Ignacio (Oxford University Press, 2023-10-18)
    Approximately 5% of Alzheimer's disease cases have an early age at onset (<65 years), with 5-10% of these cases attributed to dominantly inherited mutations and the remainder considered as sporadic. The extent to which ...
  • Evaluation and treatment approaches for neurological post-acute sequelae of COVID-19: A consensus statement and scoping review from the global COVID-19 neuro research coalition 
    Frontera, Jennifer; Guekht, Alla; Allegri, Ricardo Francisco; Ashraf, Mariam; Baykan, Betül; Crivelli, Lucía; Easton, Ava; Garcia-Azorin, David; Helbok, Raimund; Joshi, Jatin; Koehn, Julia; Koralnik, Igor; Netravathi, M.; Benedict, Michael; Nilo, Annacarmen; Özge, Aynur; Padda, Karanbir; Pellitteri, Gaia; Prasad, Kameshwar; Romozzi, Marina (Elsevier, 2023-11-15)
    Post-acute neurological sequelae of COVID-19 affect millions of people worldwide, yet little data is available to guide treatment strategies for the most common symptoms. We conducted a scoping review of PubMed/Medline ...
  • Presenilin-1 mutation position influences amyloidosis, small vessel disease, and dementia with disease stage 
    Joseph-Mathurin, Nelly; Feldman, Rebecca L.; Lu, Ruijin; Shirzadi, Zahra; Toomer, Carmen; Saint Clair, Junie R.; Ma, Yinjiao; McKay, Nicole S.; Strain, Jeremy F.; Kilgore, Collin; Friedrichsen, Karl A.; Chen, Charles D.; Gordon, Brian A.; Chen, Gengsheng; Hornbeck, Russ C.; Massoumzadeh, Parinaz; McCullough, Austin; Wang, Qing; Li, Yan; Allegri, Ricardo Francisco; Dominantly Inherited Alzheimer Network (John Wiley & Sons, 2024-02-21)
    Introduction: Amyloidosis, including cerebral amyloid angiopathy, and markers of small vessel disease (SVD) vary across dominantly inherited Alzheimer's disease (DIAD) presenilin-1 (PSEN1) mutation carriers. We investigated ...
  • Alzheimer's polygenic risk scores are associated with cognitive phenotypes in Down syndrome 
    Gorijala, Priyanka; Aslam, M. Muaaz; Dang, Lam-Ha T.; Xicota, L.; Fernández, María V.; Sung, Yun Ju; Fan, Kang-Hsien; Feingold, Eleanor; Surace, Ezequiel Ignacio; Chhatwal, Jasmeer P.; Hom, Christy L.; Dominantly Inherited Alzheimer Network; NIA-LOAD family study, for the Alzheimer's Biomarkers Consortium-Down Syndrome (ABC-DS) Investigators; Hartley, Sigan L.; Hassenstab, Jason; Perrin, Richard J.; Mapstone, Mark; Zaman, Shahid H.; Ances, Beau M.; Kamboh, M. Ilyas; Lee, Joseph H.; Cruchaga, Carlos (John Wiley & Sons, 2023-10-19)
    Introduction: This study aimed to investigate the influence of the overall Alzheimer's disease (AD) genetic architecture on Down syndrome (DS) status, cognitive measures, and cerebrospinal fluid (CSF) biomarkers. Methods: ...
  • Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer's disease 
    Johnson, Erik C. B.; Bian, Shijia; Haque, Rafi U.; Carter, E. Kathleen; Watson, Caroline M.; Gordon, Brian A.; Ping, Lingyan; Duong, Duc M.; Epstein, Michael P.; McDade, Eric; Barthélemy, Nicolas R.; Karch, Celeste M.; Xiong, Chengjie; Cruchaga, Carlos; Perrin, Richard J.; Wingo, Aliza P.; Dominantly Inherited Alzheimer Network (Nature Publishing Company, 2023-08-07)
    Alzheimer's disease (AD) pathology develops many years before the onset of cognitive symptoms. Two pathological processes-aggregation of the amyloid-β (Aβ) peptide into plaques and the microtubule protein tau into ...
  • Unravelling the landscape of Cannabis craving pharmacological treatments: a PRISMA-guided review of evidence 
    Cruz Preto, Mayra; Trevizan Kortas, Guilherme; Kanaan Blaas, Israel; Silva Lassi, Dangela Layne; Waisman Campos, Marcela; Torales, Julio César; Ventriglio, Antonio; de Azevedo-Marques Périco, Cintia; Guerra de Andrade, Arthur; Castaldelli-Maia, João Mauricio (Informa Healthcare, 2023-07-21)
    Currently, few treatments are available for craving in general, and none of them have received approval for cannabis craving. The objective of this review is to evaluate existing studies analysing treatments for cannabis ...
  • Positron emission tomography and magnetic resonance imaging methods and datasets within the Dominantly Inherited Alzheimer Network (DIAN) 
    McKay, Nicole S.; Gordon, Brian A.; Hornbeck, Russ C.; Dincer, Aylin; Flores, Shaney; Keefe, Sarah J.; Joseph-Mathurin, Nelly; Jack, Clifford R.; Koeppe, Robert A.; Millar, Peter R.; Ances, Beau M.; Chen, Charles D.; Daniels, Alisha; Hobbs, Diana A.; Jackson, Kelley; Koudelis, Deborah; Massoumzadeh, Parinaz; McCullough, Austin; Allegri, Ricardo Francisco; Dominantly Inherited Alzheimer Network (Nature Publishing Group, 2023-07-10)
    The Dominantly Inherited Alzheimer Network (DIAN) is an international collaboration studying autosomal dominant Alzheimer disease (ADAD). ADAD arises from mutations occurring in three genes. Offspring from ADAD families ...
  • Advanced structural brain aging in preclinical autosomal dominant Alzheimer disease 
    Millar, Peter R.; Gordon, Brian A.; Wisch, Julie K.; Schultz, Stephanie A.; Benzinger, Tammie L.S.; Cruchaga, Carlos; Hassenstab, Jason; Ibanez, Laura; Karch, Celeste M.; Llibre Guerra, Jorge J.; Morris, John C.; Perrin, Richard J.; Supnet Bell, Charlene; Xiong, Chengjie; Allegri, Ricardo Francisco; Berman, Sarah B.; Chhatwal, Jasmeer P.; Chrem Méndez, Patricio Alexis; Day, Gregory S.; Dominantly Inherited Alzheimer Network (BioMed Central, 2023-12-19)
    Background: "Brain-predicted age" estimates biological age from complex, nonlinear features in neuroimaging scans. The brain age gap (BAG) between predicted and chronological age is elevated in sporadic Alzheimer disease ...
  • Effectiveness of cognitive rehabilitation on mild cognitive impairment using teleneuropsychology 
    Martínez Canyazo, Carlos; Keller, Greta; Helou, María Belén; Arruabarrena, Micaela María; Corvalán, Nicolás; Carello, María Agostina; Harris, Paula; Feldman, Mónica; Fernández, Rodrigo Sebastián; Calandri, Ismael Luis; Martin, María Eugenia; Allegri, Ricardo Francisco; Crivelli, Lucía (Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento, 2023-07-24)
    The COVID-19 pandemic has affected the continuity of cognitive rehabilitation worldwide. However, the use of teleneuropsychology to provide cognitive rehabilitation has contributed significantly to the continuity of the ...
  • Network analysis of pandemic fatigue symptoms in samples from five South American countries 
    Caycho-Rodríguez, Tomás; Torales, Julio César; Ventura-León, José; Barrios Coronel, Iván; Waisman Campos, Marcela; Terrazas-Landivar, Alexandra; Viola, Laura; Vilca, Lindsey W.; Muñoz-Del-Carpio-Toia, Agueda (Sage Publications, 2024-01-26)
    Background: Pandemic fatigue generates low motivation or the ability to comply with protective behaviors to mitigate the spread of COVID-19. Aims: This study aimed to analyze the symptoms of pandemic fatigue through ...
  • Gender inequalities as contributors to dementia in Latin America and the Caribbean: what factors are missing from research? 
    Ribeiro, Fabiana S.; Crivelli, Lucía; Leist, Anja K. (Elsevier, 2023-05-11)
    The current knowledge of modifiable risk factors for dementia comes mainly from high-income countries. In Latin America and Caribbean countries, where the burden of gender and socioeconomic inequalities is greater than in ...
  • Loss of Direct Vascular Contact to Astrocytes in the Hippocampus as an Initial Event in Alzheimer's Disease. Evidence from Patients, In Vivo and In Vitro Experimental Models 
    Pomilio, Carlos; Presa, Jessica; Oses, Camila; Vinuesa, Ángeles; Bentivegna, Melisa; Gregosa, Amal; Riudavets, Miguel; Sevlever, Gustavo Emilio; Galvan, V.; Levi, Valeria; Beauquis, Juan; Saravia, Flavia (Humana Press, 2024-01-03)
    Alzheimer's disease (AD) is characterized by the accumulation of aggregated amyloid peptides in the brain parenchyma and within the walls of cerebral vessels. The hippocampus-a complex brain structure with a pivotal role ...
  • Actualización en el uso y el manejo del litio en neuropsiquiatría 
    Corrales, Alejo; Cetkovich Bakmas, Marcelo; Abadi, Andrea; Camino, Sebastián; García Bonetto, Gerardo; Márquez López Mato, Andrea; Marengo, Eliana; Abraham, Estela; Maresca, Tomás; Bagnati, Pablo M.; Dallamea, Amalia; Canseco, Diego; Morra, Carlos; Corral, Ricardo; Sotelo, Daniel; Strejilevich, Sergio; Pessio, Julián; Vilapriño, Juan José; Vilapriño, Manuel; Rebok, Federico; Vázquez, Gustavo (Polemos, 2024-01-10)
    Lithium is an alkaline metal, used for more than 60 years in psychiatry, and currently considered the gold standard in the treatment of bipolar disorder (BD). According to recent evidence, this active ingredient is useful ...
  • A task force for diagnosis and treatment of people with Alzheimer's disease in Latin America 
    Lopera, Francisco; Custodio, Nilton; Rico-Restrepo, Mariana; Allegri, Ricardo Francisco; Barrientos, José Domingo; Garcia Batres, Estuardo; Calandri, Ismael Luis; Calero Moscoso, Cristian; Caramelli, Paulo; Duran Quiroz, Juan Carlos; Jansen, Angela Marie; Mimenza Alvarado, Alberto José; Nitrini, Ricardo; Parodi, Jose F.; Ramos, Claudia; Slachevsky, Andrea; Dozzi Brucki, Sonia María (Frontiers Research Foundation, 2023-07-11)
    Alzheimer's disease (AD) represents a substantial burden to patients, their caregivers, health systems, and society in Latin America and the Caribbean (LAC). This impact is exacerbated by limited access to diagnosis, ...
  • Neuroimaging within the Dominantly Inherited Alzheimer’s Network (DIAN): PET and MRI 
    McKay, Nicole S.; Gordon, Brian A.; Hornbeck, Russ C.; Jack, Clifford R.; Koeppe, Robert A.; Flores, Shaney; Keefe, Sarah J.; Hobbs, Diana A.; Joseph-Mathurin, Nelly; Wang, Qing; Rahmani, Farzaneh; Chen, Charles D.; McCullough, Austin; Koudelis, Deborah; Chua, Jasmin; Ances, Beau M.; Millar, Peter R.; Nickels, Mike; Allegri, Ricardo Francisco; Dominantly Inherited Alzheimer Network (bioRxiv, 2022-03-30)
    The Dominantly Inherited Alzheimer Network (DIAN) Observational Study is an international collaboration studying autosomal dominant Alzheimer disease (ADAD). This rare form of Alzheimer disease (AD) is caused by mutations ...
  • Latin American Initiative for Lifestyle Intervention to Prevent Cognitive Decline (LatAm-FINGERS): Study design and harmonization 
    Crivelli, Lucía; Calandri, Ismael Luis; Kimie Suemoto, Claudia; Salinas Contreras, Rosa María; Velilla, Lina M.; Sanches Yassuda, Mónica; Caramelli, Paulo; Lopera, Francisco; Nitrini, Ricardo; Sevlever, Gustavo Emilio; Sosa, Ana Luisa; Acosta, Daisy; Bérgamo, Yanina; Clarens, María Florencia; Demey, Ignacio; Helou, María Belén; Martin, María Eugenia; Querzé, Diego; Surace, Ezequiel Ignacio; Allegri, Ricardo Francisco (Wiley, 2023-05-19)
    Introduction: Latin American Initiative for Lifestyle Intervention to Prevent Cognitive Decline (LatAm-FINGERS) is the first non-pharmacological multicenter randomized clinical trial (RCT) to prevent cognitive impairment ...
  • Biomarkers for dementia in Latin American countries: Gaps and opportunities 
    Parra, Mario A.; Orellana, Paulina; León, Tomás; Cabello, Victoria G.; Henriquez, Fernando; Gomez, Rodrigo; Avalos, Constanza; Damián, Andrés; Slachevsky, Andrea; Ibañez, Agustín; Zetterberg, Henrik; Tijms, Betty M.; Yokoyama, Jennifer S.; Piña-Escudero, Stefanie D.; Cochran, J. Nicholas; Matallana, Diana L.; Acosta, Daisy; Allegri, Ricardo Francisco (John Wiley & Sons, 2022-09-13)
    Limited knowledge on dementia biomarkers in Latin American and Caribbean (LAC) countries remains a serious barrier. Here, we reported a survey to explore the ongoing work, needs, interests, potential barriers, and opportunities ...
  • Pattern and implications of neurological examination findings in autosomal dominant Alzheimer disease 
    Vöglein, Jonathan; Franzmeier, Nicolai; Morris, John C.; Dieterich, Marianne; McDade, Eric; Simon, Mikael; Preische, Oliver; Hofmann, Anna; Hassenstab, Jason; Benzinger, Tammie L.S.; Fagan, Anne M.; Noble, James M.; Berman, Sarah B.; Graff-Radford, Neill R.; Ghetti, Bernardino; Farlow, Martin R.; Chhatwal, Jasmeer P.; Chrem Méndez, Patricio Alexis; Allegri, Ricardo Francisco; Dominantly Inherited Alzheimer Network (John Wiley & Sons, 2022-05-24)
    Introduction: As knowledge about neurological examination findings in autosomal dominant Alzheimer disease (ADAD) is incomplete, we aimed to determine the frequency and significance of neurological examination findings in ...
  • "Pandemic Fatigue" in South America: A Multi-Center Report from Argentina, Bolivia, Paraguay, Peru, and Uruguay 
    Torales, Julio César; González-Urbieta, Israel; Barrios Coronel, Iván; Waisman Campos, Marcela; Terrazas-Landivar, Alexandra; Viola, Laura; Caycho-Rodríguez, Tomás; Melgarejo, Osvaldo; Navarro, Rodrigo Eduardo; García, Oscar; Almirón Santacruz, José; Castaldelli-Maia, João Mauricio; Ventriglio, Antonio (MDPI, 2023-03-04)
    The COVID-19 pandemic has had a heavy impact on daily life, leading to physical and psychosocial consequences. Nowadays, clinicians and health researchers are particularly interested in describing and facing the long-term ...
  • Design of a Non-Interventional Study to Assess Neurologists' Perspectives and Pharmacological Treatment Decisions in Early Alzheimer's Disease 
    Saposnik, Gustavo; Sánchez-Benavidez, Gonzalo; García-Arcelay, Elena; Franco-Macías, Emilio; Bensi, Catalina; Carmelingo, Sebastián; Allegri, Ricardo Francisco; Pérez-Martíne, David A.; Maurino, Jorge (Springer, 2023-03-23)
    Introduction: The current therapeutic landscape of Alzheimer's disease (AD) is evolving rapidly. Our treatment options include new anti-amyloid-β protein disease-modifying therapies (DMTs) that decrease cognitive decline ...

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