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Diagnostic accuracy of the UDS 3.0 neuropsychological battery in a cohort with Alzheimer's disease in Colombia

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dc.contributor.author Porto, Maria F.
dc.contributor.author Benitez Agudelo, Juan Camilo
dc.contributor.author Aguirre Acevedo, Daniel Camilo
dc.contributor.author Barceló Martínez, Ernesto
dc.contributor.author Allegri, Ricardo Francisco
dc.date.accessioned 2021-03-31T14:38:44Z
dc.date.available 2021-03-31T14:38:44Z
dc.date.issued 2021-03-24
dc.identifier.citation Porto MF, Benitez Agudelo JC, Aguirre Acevedo DC, Barceló Martinez E, Allegri RF. Diagnostic accuracy of the UDS 3.0 neuropsychological battery in a cohort with Alzheimer's disease in Colombia. Appl Neuropsychol Adult. 2021 Mar 24:1-9. doi: 10.1080/23279095.2021.1897007 es_ES
dc.identifier.uri https://doi.org/10.1080/23279095.2021.1897007
dc.identifier.uri https://repositorio.fleni.org.ar/xmlui/handle/123456789/398
dc.description.abstract Background: Alzheimer's disease (AD) is a neurodegenerative disease that causes a gradual loss of cognitive functions and limits daily activities performance. Early diagnosis of AD is essential to start timely treatment. This study aimed to validate the Uniform Data Set neuropsychological battery version 3.0 (UDS 3.0) in a Colombian cohort. Methods: This study is a cross-sectional type, consecutive, incidental, with 143 persons, divided into two groups: 48 diagnosed AD cases and 95 healthy controls, between the ages of 50 and 80+, and between 1 and 19+ years of education. Results: The results indicate differences between the control group and the AD group in most battery tests. A significant correlation was found between the Montreal Cognitive Assessment (MoCA), Multilingual Naming Test (MINT), Craft Story, Benson Figure Test, P-word and F-word Phonemic Fluency Test, and their respective reference tests. Cutoff points were found based on the Youden index for each sub-test. The results indicate that all sub-tests are above the reference line of the ROC curve. Conclusion: The use of the UDS 3.0 in Colombia would help improving clinical diagnostic routes because of its high accuracy and high correlation with tests that measure general impairment; it has good sensitivity and specificity, and it can be a useful tool for AD. es_ES
dc.language.iso eng es_ES
dc.publisher Taylor & Francis es_ES
dc.rights info:eu-repo/semantics/openAccess
dc.rights.uri https://creativecommons.org/licenses/by/2.5/ar/
dc.subject Alzheimer Disease es_ES
dc.subject Enfermedad de Alzheimer es_ES
dc.subject Diagnostic Techniques, Neurological es_ES
dc.subject Técnicas de Diagnóstico Neurológico es_ES
dc.subject ROC Curve es_ES
dc.subject Curva ROC es_ES
dc.title Diagnostic accuracy of the UDS 3.0 neuropsychological battery in a cohort with Alzheimer's disease in Colombia es_ES
dc.type info:eu-repo/semantics/article es_ES
dc.type info:eu-repo/semantics/publishedVersion
dc.description.fil Fil: Porto, Maria F. Universidad de la Costa; Colombia.
dc.description.fil Fil: Benitez Agudelo, Juan Camilo. Universidad de la Costa; Colombia.
dc.description.fil Fil: Aguirre Acevedo, Daniel Camilo. Universidad de Antioquia; Colombia.
dc.description.fil Fil: Barceló Martínez, Ernesto. Universidad de la Costa; Colombia.
dc.description.fil Fil: Allegri, Ricardo Francisco. Fleni. Departamento de Neurología. Servicio de Neurología Cognitiva, Neuropsicología y Neuropsiquiatría; Argentina.
dc.relation.ispartofCOUNTRY Estados Unidos
dc.relation.ispartofCITY Filadelfia
dc.relation.ispartofTITLE Applied neuropsychology. Adult
dc.relation.ispartofISSN 2327-9109
dc.type.snrd info:ar-repo/semantics/artículo es_ES


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