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dc.contributor.author Rodríguez Murúa, Sofía
dc.contributor.author Farez, Mauricio Franco
dc.contributor.author Quintana, Francisco J.
dc.date.accessioned 2021-10-20T17:15:18Z
dc.date.available 2021-10-20T17:15:18Z
dc.date.issued 2021-10-04
dc.identifier.citation Murúa SR, Farez MF, Quintana FJ. The Immune Response in Multiple Sclerosis. Annu Rev Pathol. 2021 Oct 4. doi: 10.1146/annurev-pathol-052920-040318 es_ES
dc.identifier.uri https://doi.org/10.1146/annurev-pathol-052920-040318
dc.identifier.uri https://repositorio.fleni.org.ar/xmlui/handle/123456789/610
dc.description.abstract Multiple sclerosis (MS) is a chronic autoimmune, inflammatory, and neurodegenerative disease that affects the central nervous system (CNS). MS is characterized by immune dysregulation, which results in the infiltration of the CNS by immune cells, triggering demyelination, axonal damage, and neurodegeneration. Although the exact causes of MS are not fully understood, genetic and environmental factors are thought to control MS onset and progression. In this article, we review the main immunological mechanisms involved in MS pathogenesis. es_ES
dc.language.iso eng es_ES
dc.publisher Annual Reviews es_ES
dc.rights info:eu-repo/semantics/openAccess
dc.rights.uri https://creativecommons.org/licenses/by/2.5/ar/
dc.subject Multiple Sclerosis es_ES
dc.subject Esclerosis Múltiple es_ES
dc.subject Immunity es_ES
dc.subject Inmunidad es_ES
dc.title The Immune Response in Multiple Sclerosis es_ES
dc.type info:eu-repo/semantics/article es_ES
dc.type info:eu-repo/semantics/publishedVersion
dc.description.fil Fil: Rodríguez Murúa, Sofía. Fleni. Centro para la Investigación de Enfermedades Neuroinmunológicas; Argentina.
dc.description.fil Fil: Farez, Mauricio Franco. Fleni. Centro para la Investigación de Enfermedades Neuroinmunológicas; Argentina.
dc.description.fil Fil: Quintana, Francisco J. Ann Romney Center for Neurologic Diseases; Estados Unidos.
dc.relation.ispartofCOUNTRY Estados Unidos
dc.relation.ispartofCITY Palo Alto
dc.relation.ispartofTITLE Annual review of pathology
dc.relation.ispartofISSN 1553-4014
dc.type.snrd info:ar-repo/semantics/artículo es_ES


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