The Immune Response in Multiple Sclerosis

Rodríguez Murúa, Sofía; Farez, Mauricio Franco; Quintana, Francisco J.

dc.contributor.author	Rodríguez Murúa, Sofía
dc.contributor.author	Farez, Mauricio Franco
dc.contributor.author	Quintana, Francisco J.
dc.date.accessioned	2021-10-20T17:15:18Z
dc.date.available	2021-10-20T17:15:18Z
dc.date.issued	2021-10-04
dc.identifier.citation	Murúa SR, Farez MF, Quintana FJ. The Immune Response in Multiple Sclerosis. Annu Rev Pathol. 2021 Oct 4. doi: 10.1146/annurev-pathol-052920-040318	es_ES
dc.identifier.uri	https://doi.org/10.1146/annurev-pathol-052920-040318
dc.identifier.uri	https://repositorio.fleni.org.ar/xmlui/handle/123456789/610
dc.description.abstract	Multiple sclerosis (MS) is a chronic autoimmune, inflammatory, and neurodegenerative disease that affects the central nervous system (CNS). MS is characterized by immune dysregulation, which results in the infiltration of the CNS by immune cells, triggering demyelination, axonal damage, and neurodegeneration. Although the exact causes of MS are not fully understood, genetic and environmental factors are thought to control MS onset and progression. In this article, we review the main immunological mechanisms involved in MS pathogenesis.	es_ES
dc.language.iso	eng	es_ES
dc.publisher	Annual Reviews	es_ES
dc.rights	info:eu-repo/semantics/openAccess
dc.rights.uri	https://creativecommons.org/licenses/by/2.5/ar/
dc.subject	Multiple Sclerosis	es_ES
dc.subject	Esclerosis Múltiple	es_ES
dc.subject	Immunity	es_ES
dc.subject	Inmunidad	es_ES
dc.title	The Immune Response in Multiple Sclerosis	es_ES
dc.type	info:eu-repo/semantics/article	es_ES
dc.type	info:eu-repo/semantics/publishedVersion
dc.description.fil	Fil: Rodríguez Murúa, Sofía. Fleni. Centro para la Investigación de Enfermedades Neuroinmunológicas; Argentina.
dc.description.fil	Fil: Farez, Mauricio Franco. Fleni. Centro para la Investigación de Enfermedades Neuroinmunológicas; Argentina.
dc.description.fil	Fil: Quintana, Francisco J. Ann Romney Center for Neurologic Diseases; Estados Unidos.
dc.relation.ispartofCOUNTRY	Estados Unidos
dc.relation.ispartofCITY	Palo Alto
dc.relation.ispartofTITLE	Annual review of pathology
dc.relation.ispartofISSN	1553-4014
dc.type.snrd	info:ar-repo/semantics/artículo	es_ES