Changes in cognitive functioning after COVID-19: A systematic review and meta-analysis

Crivelli, Lucía; Palmer, Katie; Calandri, Ismael Luis; Guekht, Alla; Beghi, Ettore; Carroll, William; Frontera, Jennifer; García-Azorín, David; Westenberg, Érica; Winkler, Andrea Sylvia; Mangialasche, Francesca; Allegri, Ricardo Francisco; Kivipelto, Miia

dc.contributor.author	Crivelli, Lucía
dc.contributor.author	Palmer, Katie
dc.contributor.author	Calandri, Ismael Luis
dc.contributor.author	Guekht, Alla
dc.contributor.author	Beghi, Ettore
dc.contributor.author	Carroll, William
dc.contributor.author	Frontera, Jennifer
dc.contributor.author	García-Azorín, David
dc.contributor.author	Westenberg, Érica
dc.contributor.author	Winkler, Andrea Sylvia
dc.contributor.author	Mangialasche, Francesca
dc.contributor.author	Allegri, Ricardo Francisco
dc.contributor.author	Kivipelto, Miia
dc.date.accessioned	2023-01-06T14:48:42Z
dc.date.available	2023-01-06T14:48:42Z
dc.date.issued	2022-05
dc.identifier.citation	Crivelli L, Palmer K, Calandri I, Guekht A, Beghi E, Carroll W, Frontera J, García-Azorín D, Westenberg E, Winkler AS, Mangialasche F, Allegri RF, Kivipelto M. Changes in cognitive functioning after COVID-19: A systematic review and meta-analysis. Alzheimers Dement. 2022 May;18(5):1047-1066. doi: 10.1002/alz.12644. Epub 2022 Mar 17.	es_ES
dc.identifier.uri	https://doi.org/10.1002/alz.12644
dc.identifier.uri	https://repositorio.fleni.org.ar/xmlui/handle/123456789/763
dc.description.abstract	Introduction: We conducted a systematic review and meta-analysis of the cognitive effects of coronavirus disease 2019 (COVID-19) in adults with no prior history of cognitive impairment. Methods: Searches in Medline/Web of Science/Embase from January 1, 2020, to December 13, 2021, were performed following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A meta-analysis of the Montreal Cognitive Assessment (MoCA) total score comparing recovered COVID-19 and healthy controls was performed. Results: Oof 6202 articles, 27 studies with 2049 individuals were included (mean age = 56.05 years, evaluation time ranged from the acute phase to 7 months post-infection). Impairment in executive functions, attention, and memory were found in post-COVID-19 patients. The meta-analysis was performed with a subgroup of 290 individuals and showed a difference in MoCA score between post-COVID-19 patients versus controls (mean difference = -0.94, 95% confidence interval [CI] -1.59, -0.29; P = .0049). Discussion: Patients recovered from COVID-19 have lower general cognition compared to healthy controls up to 7 months post-infection.	es_ES
dc.language.iso	eng	es_ES
dc.rights	info:eu-repo/semantics/openAccess
dc.rights.uri	https://creativecommons.org/licenses/by/2.5/ar/
dc.subject	COVID-19	es_ES
dc.subject	Cognitive Dysfunction	es_ES
dc.subject	Disfunción Cognitiva	es_ES
dc.title	Changes in cognitive functioning after COVID-19: A systematic review and meta-analysis	es_ES
dc.type	info:eu-repo/semantics/article	es_ES
dc.type	info:eu-repo/semantics/publishedVersion
dc.description.fil	Fil: Crivelli, Lucía. Fleni. Departamento de Neurología. Servicio de Neurología Cognitiva, Neuropsicología y Neuropsiquiatría; Argentina.
dc.description.fil	Fil: Calandri, Ismael Luis. Fleni. Departamento de Neurología. Servicio de Neurología Cognitiva, Neuropsicología y Neuropsiquiatría; Argentina.
dc.description.fil	Fil: Allegri, Ricardo Francisco. Fleni. Departamento de Neurología. Servicio de Neurología Cognitiva, Neuropsicología y Neuropsiquiatría; Argentina.
dc.description.fil	Fil: Palmer, Katie. Karolinska Institutet; Suecia. FINGERS Brain Health Institute; Suecia.
dc.description.fil	Fil: Guekht, Alla. Pirogov Russian National Research University; Rusia.
dc.description.fil	Fil: Beghi, Ettore. Instituto di Ricerche Farmacologiche Mario Negri IRCCS; Italia.
dc.description.fil	Fil: Carroll, William. Sir Charles Gairdner Hospital and Center for Neuromuscular and Neurological Disorders Perron Institute; Australia.
dc.description.fil	Fil: Frontera, Jennifer. NYU Grossman School of Medicine; Estados Unidos.
dc.description.fil	Fil: García-Azorín, David. Hospital Clínico Universitario de Valladolid; España.
dc.description.fil	Fil: Westenberg, Erica. Technical University of Munich; Alemania.
dc.description.fil	Fil: Winkler, Andrea Sylvia. University of Oslo; Noruega.
dc.description.fil	Fil: Mangialasche, Francesca. Karolinska Institutet; Suecia. FINGERS Brain Health Institute; Suecia.
dc.description.fil	Fil: Mangialasche, Francesca. Karolinska Institutet; Suecia. FINGERS Brain Health Institute; Suecia. Karolinska University Hospital; Suecia. Imperial College London, London; Reino Unido. University of Eastern Finland; Finlandia.
dc.relation.ispartofVOLUME	18
dc.relation.ispartofNUMBER	5
dc.relation.ispartofPAGINATION	1047-1066.
dc.relation.ispartofCOUNTRY	Estados Unidos
dc.relation.ispartofCITY	Hoboken
dc.relation.ispartofTITLE	Alzheimer's & dementia : the journal of the Alzheimer's Association
dc.relation.ispartofISSN	1552-5279
dc.type.snrd	info:ar-repo/semantics/artículo	es_ES