Repositorio Institucional FLENI: Envíos recientes

  • Palbociclib Effectively Halts Proliferation but Fails to Induce Senescence in Patient-Derived Glioma Stem Cells 
    Morris-Hanon, Olivia; Marazita, Mariela Claudia; Romorini, Leonardo; Isaja, Luciana; Fernandez-Espinosa, Damián Darío; Sevlever, Gustavo Emilio; Scassa, María Élida; Videla Richardson, Guillermo Agustín (Springer, 2019-05-23)
    Glioblastoma multiforme is the most aggressive primary brain tumor. Current knowledge suggests that the growth and recurrence of these tumors are due in part to the therapy-resistant glioma stem cell subpopulation, which ...
  • R534C mutation in hERG causes a trafficking defect in iPSC-derived cardiomyocytes from patients with type 2 long QT syndrome 
    Mesquita, Fernanda C.P.; Arantes, Paulo C.; Kasai-Brunswick, Tais Hanae; Araujo, Dayana S.; Gubert, Fernanda; Monnerat, Gustavo; Silva dos Santos, Danúbia; Neiman, Gabriel; Leitão, Isabela C.; Barbosa, Raiana A. Q.; Coutinho, Jorge L.; Vaz, Isadora M.; dos Santos, Marcus N.; Borgonovo, Tamara; Cruz, Fernando E. S.; Miriuka, Santiago Gabriel; Medei, Emiliano H.; Campos de Carvalho, Antonio C.; Carvalho, Adriana B. (Nature Publishing Group, 2019-12-16)
    Patient-specific cardiomyocytes obtained from induced pluripotent stem cells (CM-iPSC) offer unprecedented mechanistic insights in the study of inherited cardiac diseases. The objective of this work was to study a type 2 ...
  • Clinical, pathophysiological and genetic features of motor symptoms in autosomal dominant Alzheimer’s disease 
    Vöglein, Jonathan; Paumier, Katrina; Jucker, Mathias; Preische, Oliver; McDade, Eric; Hassenstab, Jason; Benzinger, Tammie L.S.; Noble, James M.; Berman, Sarah B.; Graff-Radford, Neill R.; Ghetti, Bernardino; Farlow, Martin R.; Chhatwal, Jasmeer P.; Salloway, Stephen; Xiong, Chengjie; Karch, Celeste M.; Cairns, Nigel; Mori, Hiroshi; Schofield, Peter R.; Masters, Colin L.; Goate, Alison M.; Buckles, Virginia; Fox, Nick C.; Rossor, Martin N.; Chrem Méndez, Patricio Alexis; Allegri, Ricardo Francisco; Ringman, John M.; Höglinger, Günter U.; Steiner, Harald; Dieterich, Marianne; Haass, Christian; Laske, Christoph; Morris, John C.; Bateman, Randall J.; Danek, Adrian; Levin, Johannes; Dominantly Inherited Alzheimer Network (Oxford, 2019-03-20)
    Owing to an early and marked deposition of amyloid-β in the basal ganglia, autosomal dominant Alzheimer’s disease could distinctly involve motor symptoms. Therefore, we aimed to assess the prevalence and characteristics ...
  • Mechanical thrombectomy for reperfusion of acute ischemic stroke in a Stroke Unit in Argentina 
    Alet, Matías Javier; Rodríguez Lucci, Federico; Ameriso, Sebastián Francisco (Associacao Arquivos De Neuro-Psiquitria Dr Oswaldo Lange, 2020-01)
    Objective: Stroke is an important cause of morbidity and mortality worldwide. Reperfusion therapy with intravenous tissue plasminogen activator (IV-tPA) was first implemented in 1996. More recently, endovascular reperfusion ...
  • Acute amnestic syndromes 
    Alessandro, Lucas; Ricciardi, Mario Emiliano; Chaves, Hernán; Allegri, Ricardo Francisco (Elsevier, 2020-03-18)
    Acute amnestic syndromes are usually rare clinical events occurring in emergency situations. Etiological diagnosis can be challenging and underlying causes diverse. They can be transient and totally reversible, or accompanied ...
  • Differential Diagnosis in Late Onset Multiple Sclerosis 
    Yorio, Florencia; Marrodán, Mariano; Farez, Mauricio Franco; Correale, Jorge (AAN, 2019-04-09)
    Objective: To identify clinical-radiological characteristics of patients consulting with suspected Late Onset Multiple Sclerosis (LOMS). Background: LOMS is defined by clinical presentation after 50 years of age, being ...
  • Deep Learning Neural Networks Highly Predict Very Early Onset of Pluripotent Stem Cell Differentiation 
    Waisman, Ariel; La Greca, Alejandro; Möbbs, Alan Miqueas; Scarafía, María Agustina; Santín Velazque, Natalia Lucía; Neiman, Gabriel; Moro, Lucía Natalia; Luzzani, Carlos Daniel; Sevlever, Gustavo Emilio; Guberman, Alejandra S.; Miriuka, Santiago Gabriel (Elsevier, 2019-04-09)
    Deep learning is a significant step forward for developing autonomous tasks. One of its branches, computer vision, allows image recognition with high accuracy thanks to the use of convolutional neural networks (CNNs). Our ...
  • Cell cycle dynamics of mouse embryonic stem cells in the ground state and during transition to formative pluripotency 
    Waisman, Ariel; Sevlever, Federico; Costa, Martín Elías; Cosentino, María Soledad; Miriuka, Santiago Gabriel; Ventura, Alejandra C.; Guberman, Alejandra S. (Nature Publishing Group, 2019-05-29)
    Mouse embryonic stem cells (mESCs) can be maintained as homogeneous populations in the ground state of pluripotency. Release from this state in minimal conditions allows to obtain cells that resemble those of the early ...
  • Video Head Impulse Test Contributes to Susac Syndrome Diagnosis 
    Marrodán, Mariano; Laffue, Alfredo Hernan; Fiol, Marcela Paula; Correale, Jorge; Gualtieri, Francisco José (Springer, 2019-05-07)
    Resumen no disponible
  • Disease activity impacts disability progression in primary progressive multiple sclerosis 
    Marrodán, Mariano; Bensi, Catalina; Pappolla, Agustín; Rojas, Juan Ignacio; Gaitán, María Inés; Ysrraelit, María Célica; Negrotto, Laura; Fiol, Marcela Paula; Patrucco, Liliana; Cristiano, Edgardo; Farez, Mauricio Franco; Correale, Jorge (Elsevier, 2019-12-14)
    Background Although solid information on the natural history of primary progressive multiple sclerosis (PPMS) is available, evidence regarding impact of disease activity on PPMS progression remains controversial. Objective To ...
  • Analysis of the expression of PIWI-interacting RNAs during cardiac differentiation of human pluripotent stem cells 
    La Greca, Alejandro; Scarafía, María Agustina; Hernández Cañás, María Clara; Pérez, Nelba; Castañeda, Sheila; Colli, Carolina; Miqueas Möbbs, Alan; Santín Velazque, Natalia Lucía; Neiman, Gabriel; Garate, Ximena; Aban, Cyntia; Waisman, Ariel; Moro, Lucía Natalia; Sevlever, Gustavo Emilio; Luzzani, Carlos Daniel; Miriuka, Santiago Gabriel (bioRxiv, 2019-05-21)
    El artículo es un preprint que aún no ha pasado por revisión por pares PIWI-interacting RNAs (piRNAs) are a class of non-coding RNAs initially thought to be restricted almost exclusively to germ line cells. In recent ...
  • Reply to "Reversible Cerebral Vasoconstriction Syndrome Responsive to Intravenous Milrinone" 
    Hawkes, Maximiliano Alberto; Wainsztein, Néstor Adrián; Hlavnicka, Alejandro Félix (Humana Press, 2020-04)
    Resumen no disponible
  • Teaching NeuroImages: A Disintegrating Rock 
    Hawkes, Maximiliano Alberto; Rabinstein, Alejandro A. (Lippincott Williams & Wilkins, 2019-04-16)
    Resumen no disponible
  • Multidisciplinary Rehabilitation for Adult Patients With Stroke 
    Alessandro, Lucas; Olmos, Lisandro Emilio; Bonamico, Lucas; Muzio, Diana María; Ahumada, Martina H.; Russo, María Julieta; Allegri, Ricardo Francisco; Gianella, Matías Gabriel; Campora, Horacio; Delorme, Ricardo; Vescovo, María Ester; Lado, Vanina; Mastroberti, Liliana Roxana; Butus, Ayelén; Galluzzi, Hugo Daniel; Décima, Graciela; Ameriso, Sebastián Francisco (Fundación Revista Medicina, 2020-01)
    It is estimated that two thirds of people who have suffered a stroke have sequels that condition their quality of life. The rehabilitation of the stroke is a complex process, which requires the multidisciplinary approach ...
  • Neurological Prognostication After Cardiac Arrest in the Era of Target Temperature Management 
    Hawkes, Maximiliano Alberto; Rabinstein, Alejandro A. (Current Science Inc, 2019-02-09)
    Purpose of Review The purpose of this study is to provide an updated review on neurological prognostication in comatose patients after cardiac arrest in light of current targeted temperature management (TTM) strategies. Recent ...
  • Importance of Understanding the Real Cause of Death in Status Epilepticus 
    Hawkes, Maximiliano Alberto; Hocker, Sara (Academic Press, 2019-12-24)
    Resumen no disponible
  • Ontogenetic Oligodendrocyte Maturation Through Gestational Iron Deprivation: The Road Not Taken 
    Guitart, María Eugenia; Vence, Marianela; Correale, Jorge; Pasquini, Juana María; Rosato-Siri, María Victoria (Wiley, 2019-06-04)
    Developmental iron deficiency (dID) models facilitate the study of specific oligodendrocyte (OL) requirements for their progression to a mature state and subsequent contribution to myelination. In the current work, we used ...
  • Blood Pressure and Orthostatic Hypotension as Measures of Autonomic Dysfunction in Patients From the Transthyretin Amyloidosis Outcomes Survey (THAOS) 
    González-Duarte, Alejandra; Barroso, Fabio Adrián; Mundayat, Rajiv; Shapiro, Bryan (Elsevier, 2019-10-23)
    Introduction Autonomic dysfunction, an early symptom of transthyretin amyloidosis (ATTR amyloidosis), requires investigations not readily available in many clinics. Although monitoring of orthostatic hypotension (OH) will ...
  • Non-β-Blocking Carvedilol Analog, VK-II-86, Prevents Ouabain-Induced Cardiotoxicity 
    Gonano, Luis A.; Sepúlveda, Marisa; Morell, Malena; Toteff, Tamara; Racioppi, María Florencia; Lascano, Elena; Negroni, Jorge; Fernández Ruocco, María Julieta; Medei, Emiliano H.; Neiman, Gabriel; Miriuka, Santiago Gabriel; Back, Thomas G.; Wayne Chen, S.R.; Mattiazzi, Alicia; Vila Petroff, Martin (Japanese Circulation Society, 2018-12-25)
    Background: It has been shown that carvedilol and its non β-blocking analog, VK-II-86, inhibit spontaneous Ca2+ release from the sarcoplasmic reticulum (SR). The aim of this study is to determine whether carvedilol and ...
  • An Attypical Choroid Plexus Papilloma of IV Ventricle with Dissemination to a Sacral Tarlov Cyst: A Case Report 
    Gentile, Aixa; Diez, Blanca; Cervio, Andrés Eduardo; Arakaki, Naomi; Cejas, Claudia Patricia (Remedy Publications, 2019-02-07)
    Choroid Plexus Papillomas (CPP) is uncommon tumors of the CNS. Atypical CPPs represent an intermediate-grade subtype (Grade II) introduced in the update 2007 of the WHO classification. Distal spread of atypical CPPs ...