Enfermedades Desmielinizantes.artículos: Recent submissions

Anzeige der Dokumente 21-40 von 124

Clinical characterization of long-term multiple sclerosis (COLuMbus) patients in Argentina: A cross-sectional non-interventional study

Deri, Norma; Barboza, Andrés G.; Vrech, Carlos; Rey, Roberto D.; Burgos, Marcos; Fiol, Marcela Paula; Calvo Vildoso, Christian; Patrucco, Liliana; José, Gustavo; Aliberti, Paula; Chirico, Daniela; Federico, María B.; Seifer, Gustavo; Piedrabuena, Raúl (Elsevier, 2023-12-31)

Background: Most Multiple Sclerosis (MS) clinical trials fail to assess the long-term effects of disease-modifying therapies (DMT) or disability. Methods: COLuMbus was a single-visit, cross-sectional study in Argentina ...
Frequency of new asymptomatic MRI lesions during attacks and follow-up of patients with NMOSD in a real-world setting

Carnero Contentti, Edgar; López, Pablo Adrián; Tkachuk, Verónica A.; Vrech, Carlos; Zarate, María Agustina; Correale, Jorge; Deri, Norma; Luetic, Geraldine G.; Marrodán, Mariano; Pagani Cassará, Fátima; Tavolini, Darío; Ysrraelit, María Célica; Balbuena Aguirre, María Eugenia; Hryb, Javier Pablo; Chiganer, Edson Hernán; Leguizamon, Felisa; Knorre, Eduardo; Zanga, Gisela; Pestchanker, Claudia; Barboza, Andrés G. (Sage, 2023-07-25)

Background: We aimed to assess the frequency of new asymptomatic lesions on brain and spinal imaging (magnetic resonance imaging (MRI)) and their association with subsequent relapses in a large cohort of neuromyelitis ...
Differential diagnosis of suspected multiple sclerosis: an updated consensus approach

Solomon, Andrew J.; Arrambide, Georgina; Brownlee, Wallace J.; Flanagan, Eoin P.; Amato, María Pía; Amezcua, Lilyana; Banwell, Brenda L.; Barkhof, Frederik; Corboy, John R.; Correale, Jorge; Fujihara, Kazuo; Graves, Jennifer; Harnegie, Mary Pat; Hemmer, Bernhard; Lechner-Scott, Jeannette; Marrie, Ruth Ann; Newsome, Scott D.; Rocca, Maria A.; Royal, Walter; Waubant, Emmanuelle L. (Lancet, 2023-07-19)

Accurate diagnosis of multiple sclerosis requires careful attention to its differential diagnosis-many disorders can mimic the clinical manifestations and paraclinical findings of this disease. A collaborative effort, ...
Global Barriers to the Diagnosis of Multiple Sclerosis: Data From the Multiple Sclerosis International Federation Atlas of MS, Third Edition

Solomon, Andrew J.; Marrie, Ruth Ann; Viswanathan, Shanthi; Correale, Jorge; Magyari, Melinda; Robertson, Neil P.; Saylor, Deanna R.; Kaye, Wendy; Rechtman, Lindsay; Bae, Eunchan; Shinohara, Russell; King, Rachel; Laurson-Doube, Joanna; Helme, Anne (Lippincott Williams & Wilkins, 2023-06-15)

Background and objectives: Recent data suggest increasing global prevalence of multiple sclerosis (MS). Early diagnosis of MS reduces the burden of disability-adjusted life years and associated health care costs. Yet ...
Latin American consensus recommendations on the risk of infections in people with multiple sclerosis treated with disease modifying drugs

Silva, Berenice Anabel; Carnero Contentti, Edgar; Becker, Jefferson; Carranza, José I.; Correa Díaz, Edgar Patricio; Galleguillos Goiry, Lorna; Garcea, Orlando; Gracia, Fernando; Hamuy, Fernando; Macías, Miguel Angel; Navas, Carlos; Nuñez, Sebastián; Rojas, Juan Ignacio; Farez, Mauricio Franco; Alonso, Ricardo; López, Pablo Adrián (Elsevier, 2023-06-20)

Introduction: The emergence of several therapeutic options in multiple sclerosis (MS), which significantly modify the immune system functioning, has led to the need for the consideration of additional factors, such as risk ...
Serological response to SARS-CoV-2 vaccines in patients with multiple sclerosis in Argentina

Rojas, Juan Ignacio; Alonso, Ricardo; Cabrera, Mariela; Carnero Contentti, Edgar; Cristiano, Edgardo; Deri, Norma; Hryb, Javier Pablo; López, Pablo Adrián; Luetic, Geraldine G.; Patrucco, Liliana; Tkachuk, Verónica A.; Ysrraelit, María Célica; Zanga, Gisela; Cruces, Leonel; Turk, Gabriela; Longueira, Yesica; Laufer, Natalia; Nuñez, Sebastián (Fundación Revista Medicina, 2023-03-02)

Introduction: The objective was to assess the immunogenicity and effectiveness of vaccines against SARSCoV-2 in multiple sclerosis (MS) patients included in the Argentinean MS registry. Methods: A prospective cohort ...
Clinically relevant increases in serum neurofilament light chain and glial fibrillary acidic protein in patients with Susac syndrome

Plantone, Domenico; Sabatelli, Eleonora; Locci, Sara; Marrodán, Mariano; Laakso, Sini M.; Mateen, Farrah J.; Feresiadou, Amalia; Buelens, Tom; Bianco, Assunta; Fiol, Marcela Paula; Correale, Jorge; Tienari, Pentti; Calabresi, Paolo; De Stefano, Nicola; Iorio, Raffaele (Wiley, 2023-06-19)

Background and purpose: Serum levels of neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) are promising neuro-axonal damage and astrocytic activation biomarkers. Susac syndrome (SS) is an ...
Clinical characteristics, course and prognosis of Multiple Sclerosis patients with epilepsy. A case control study: MS and epilepsy

Sánchez, M.; Marone, Abril; Silva, Walter H.; Marrodán, Mariano; Correale, Jorge (Elsevier, 2024-01-02)

Background and purpose: Although more common than in the general population, seizures are an atypical manifestation of multiple sclerosis (MS) and their pathophysiology is not well understood. This study aims to examine ...
Clinical impact of gender and age at onset on disease trajectory in primary progressive multiple sclerosis patients

Camerlingo, Sebastián; Rubinstein, Fernando; Ysrraelit, María Célica; Correale, Jorge; Carnero Contentti, Edgar; Rojas, Juan Ignacio; Patrucco, Liliana; Del Valle Leguizamon, Felisa; Tkachuk, Verónica A.; Fernández Liguori, Nora; Cristiano, Edgardo; Mainella, Carolina; Zanga, Gisela; Carrá, Adriana; Marrodán, Mariano; Martínez, Alejandra Diana; Silva, Berenice Anabel; Alonso, Ricardo (Sage Publications, 2024-01-21)

Background and objectives: Primary-progressive multiple sclerosis (PPMS) is characterized by gradual neurological deterioration without relapses. This study aimed to investigate the clinical impact of gender and age at ...
European Committee for Treatment and Research in Multiple Sclerosis and European Academy of Neurology consensus on vaccination in people with multiple sclerosis: Improving immunization strategies in the era of highly active immunotherapeutic drugs

Otero-Romero, Susana; Lebrun-Frenay, Christine; Reyes, Saúl; Amato, María Pía; Campins, Magda; Farez, Mauricio Franco; Filippi, Massimo; Hacohen, Yael; Hemmer, Bernhard; Juuti, Rosa; Magyari, Melinda; Oreja-Guevara, Celia; Siva, Aksel; Vukusic, Sandra; Tintoré, Mar (Wiley, 2023-06-09)

Background and purpose With the new highly active drugs available for people with multiple sclerosis (pwMS), vaccination becomes an essential part of the risk management strategy. We aimed to develop a European evidence-based ...
ECTRIMS/EAN consensus on vaccination in people with multiple sclerosis: Improving immunization strategies in the era of highly active immunotherapeutic drugs

Otero-Romero, Susana; Lebrun-Frenay, Christine; Reyes, Saúl; Amato, María Pía; Campins, Magda; Farez, Mauricio Franco; Filippi, Massimo; Hacohen, Yael; Hemmer, Bernhard; Juuti, Rosa; Magyari, Melinda; Oreja-Guevara, Celia; Siva, Aksel; Vukusic, Sandra; Tintoré, Mar (Sage, 2023-06-09)

Background: With the new highly active drugs available for people with multiple sclerosis (pwMS), vaccination becomes an essential part of the risk management strategy. Objective: To develop a European evidence-based ...
2-Chlorodeoxyadenosine (Cladribine) preferentially inhibits the biological activity of microglial cells

Aybar, Florencia; Pérez, María Julia; Marcora, María Silvina; Samman, María Eugenia; Marrodán, Mariano; Pasquini, Juana María; Correale, Jorge (Elsevier Science, 2022-01-29)

Cladribine (2CdA) is a synthetic chlorinated purine nucleoside analogue which acts as a pro-drug requiring intracellular phosphorylation to be activated. It is biologically active in selected cell types, which results in ...
The risk of infections for multiple sclerosis and neuromyelitis optica spectrum disorder disease-modifying treatments: Eighth European Committee for Treatment and Research in Multiple Sclerosis Focused Workshop Review. April 2021

Tur, Carmen; Dubessy, Anne-Laure; Otero-Romero, Susana; Amato, María Pía; Derfuss, Tobías; Di Pauli, Franziska; Iacobaeus, Ellen; Mycko, Marcin; Abboud, Hesham; Achiron, Anat; Bellinvia, Angelo; Boyko, Alexey; Casanova, Jean-Laurent; Clifford, David; Dobson, Ruth; Farez, Mauricio Franco; Filippi, Massimo; Fitzgerald, Kathryn C.; Fonderico, Mattia; Gouider, Riadh (Stockton Press, 2022-02-23)

Over the recent years, the treatment of multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) has evolved very rapidly and a large number of disease-modifying treatments (DMTs) are now available. ...
From the prodromal stage of multiple sclerosis to disease prevention

Marrie, Ruth Ann; Allegretta, Mark; Barcellos, Lisa F.; Bebo, Bruce; Calabresi, Peter A.; Correale, Jorge; Davis, Benjamin; De Jager, Philip L.; Gasperi, Christiane; Greenbaum, Carla; Helme, Anne; Hemmer, Bernhard; Kanellis, Pamela; Kostich, Walter; Landsman, Douglas; Lebrun-Frenay, Christine; Makhani, Naila; Munger, Kassandra L.; Okuda, Darin T.; Ontaneda, Daniel (Nature Pub. Group, 2022-07-15)

A prodrome is an early set of signs or symptoms that indicate the onset of a disease before more typical symptoms develop. Prodromal stages are well recognized in some neurological and immune-mediated diseases such as ...
Guía de práctica clínica: tratamiento agudo de las enfermedades inflamatorio-desmielinizantes del sistema nervioso central: esclerosis múltiple, espectro de la neuromielitis óptica, encefalomielitis diseminada aguda, enfermedades asociadas a anticuerpos antiglicoproteína de la membrana del oligodendrocito, mielitis aguda y neuritis óptica. Elaborada por el Grupo de Trabajo de Enfermedades Desmielinizantes. Sociedad Neurológica Argentina

Hryb, Javier Pablo; Tavolini, Darío; Pagani Cassará, Fátima; Silva, Berenice Anabel; Rojas, Juan Ignacio; Sinay, Vladimiro; Tkachuk, Verónica A.; Alonso, Ricardo; Carnero Contentti, Edgar; Ysrraelit, María Célica; Cohen, Leila; Rotta Escalante, Roberto; Mainella, Carolina; Diana Martínez, Alejandra; Liwacki, Susana; Luetic, Geraldine G.; Bestoso, Santiago; Vázquez, Guido; Piedrabuena, Raúl; Vrech, Carlos (Elsevier, 2023-06-12)

Introducción El tratamiento adecuado y a tiempo de las manifestaciones agudas de las enfermedades inflamatorias-desmielinizantes del sistema nervioso central incluyendo a la encefalomielitis diseminada aguda, los síndromes ...
Long-term follow-up of patients with relapsing multiple sclerosis from the CLARITY/CLARITY Extension cohort of CLASSIC-MS: An ambispective study

Giovannoni, Gavin; Boyko, Alexey; Correale, Jorge; Edan, Gilles; Freedman, Mark S.; Montalban, Xavier; Rammohan, Kottil; Stefoski, Dusan; Yamout, Bassem; Leist, Thomas; Aydemir, Aida; Borsi, Laszlo; Verdun di Cantogno, Elisabetta (Sage, 2023-04-03)

Background: CLASSIC-MS evaluated the long-term efficacy of cladribine tablets in patients with relapsing multiple sclerosis. Objective: Report long-term mobility and disability beyond treatment courses received in ...
Estrategias de manejo de terapias de alta eficacia para esclerosis múltiple en la práctica clínica

Barboza, Andrés G.; Correale, Jorge; Alonso, Ricardo; Burgos, Marcos; Cáceres, Fernando; Carnero Contentti, Edgar; Carrá, Adriana; Cristiano, Edgardo; Fiol, Marcela Paula; Garcea, Orlando; Luetic, Geraldine G.; Patrucco, Liliana; Piedrabuena, Raúl; Rojas, Juan Ignacio; Silva, Berenice Anabel; Sinay, Vladimiro; Vrech, Carlos; Ysrraelit, María Célica (Elsevier, 2023-06-12)

Introducción En la actualidad existe un importante número de opciones en terapias modificadoras de la enfermedad en esclerosis múltiple (EM), las cuales pueden ser categorizadas como de baja, moderada y alta eficacia según ...
Performance of McDonald 2017 multiple sclerosis diagnostic criteria and evaluation of genetic ancestry in patients with a first demyelinating event in Argentina

Marrodán, Mariano; Piedrabuena, María Agustina; Gaitán, María Inés; Fiol, Marcela Paula; Ysrraelit, María Célica; Carnero Contentti, Edgar; López, Pablo Adrián; Peuchot, Verónica; Correale, Jorge (Sage, 2023-03-21)

Background: Information on performance of multiple sclerosis (MS) diagnostic criteria is scarce for populations from Latin America, Asia, or the Caribbean. Objective: To assess performance of revised 2017 McDonald ...
Are highly active and aggressive multiple sclerosis the same entity?

Correale, Jorge; Rush, Carolina A.; Barboza, Andrés G. (Frontiers Research Foundation, 2023-03-03)

Resumen no disponible.
Disease activity after discontinuation of disease-modifying therapies in patients with multiple sclerosis in Argentina: data from the nationwide registry RelevarEM

Zanga, Gisela; Portinari, Carla; Barber, Josefina; Ibañez, Tomas; Brolese, Lucía; Pappolla, Agustín; Miguez, Jimena; Patrucco, Liliana; Cristiano, Edgardo; Deri, Norma; Tkachuk, Verónica A.; Vrech, Carlos; Cohen, Leila; Alonso, Ricardo; Garcea, Orlando; Ysrraelit, María Célica; Marrodán, Mariano; Gaitán, María Inés; Correale, Jorge; RELEVAREM Study Group (Taylor & Francis, 2022-10-02)

Introduction: The discontinuation of disease-modifying therapies (DMTs) in multiple sclerosis (MS) is commonly seen in real-world settings due to several factors. Area cover: The aim of this study is to describe the ...

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