Enfermedades Desmielinizantes.artículos: Recent submissions

  • Computational basis of decision-making impairment in multiple sclerosis 
    Fernández, Rodrigo Sebastián; Crivelli, Lucía; Pedreira, María Eugenia; Allegri, Ricardo Francisco; Correale, Jorge (Sage, 2021-12-21)
    Background: Multiple sclerosis (MS) is commonly associated with decision-making, neurocognitive impairments, and mood and motivational symptoms. However, their relationship may be obscured by traditional scoring ...
  • Seasonal variation in attacks of neuromyelitis optica spectrum disorders and multiple sclerosis: Evaluation of 794 attacks from a nationwide registry in Argentina 
    Carnero Contentti, Edgar; López, Pablo Adrián; Pettinicchi, Juan Pablo; Criniti, Juan; Pappolla, Agustín; Miguez, Jimena; Patrucco, Liliana; Cristiano, Edgardo; Liwacki, Susana; Tkachuk, Verónica A.; Balbuena Aguirre, María Eugenia; Vrech, Carlos; Deri, Norma; Correale, Jorge; Marrodán, Mariano; Ysrraelit, María Célica; Leguizamon, Felisa; Luetic, Geraldine G.; Menichini, María Laura; Tavolini, Darío (Elsevier, 2021-12-13)
    Background: Identification of triggers that potentially instigate attacks in neuromyelitis optica spectrum disorders (NMOSD) and multiple sclerosis (MS) has remained challenging. We aimed to analyze the seasonality of NMOSD ...
  • Clinical and demographic characteristics of male MS patients included in the national registry-RelevarEM. Does sex or phenotype make the difference in the association with poor prognosis? 
    Luetic, Geraldine G.; Menichini, María Laura; Vrech, Carlos; Pappolla, Agustín; Patrucco, Liliana; Cristiano, Edgardo; Marrodán, Mariano; Ysrraelit, María Célica; Fiol, Marcela Paula; Correale, Jorge; Cohen, Leila; Alonso, Ricardo; Silva, Berenice Anabel; Casas, Magdalena; Garcea, Orlando; Deri, Norma; Burgos, Marcos; Liwacki, Susana; Tkachuk, Verónica A.; Barboza, Andrés G. (Elsevier, 2021-11-17)
    Background In multiple sclerosis demographics there is a well-known female prevalence and male patients have been less specifically evaluated in clinical studies, though some clinical differences have been reported between ...
  • Guía de práctica clínica: tratamiento sintomático de esclerosis múltiple. Grupo de Trabajo de Enfermedades Desmielinizantes. Sociedad Neurológica Argentina 
    Barboza, Andrés G.; Sinay, Vladimiro; Zanga, Gisela; Alonso, Ricardo; Silva, Berenice Anabel; Saladino, María Laura; Cohen, Leila; Luetic, Geraldine G.; Camerlingo, Sebastián; Ysrraelit, María Célica; Tenembaum, S. N.; Tarulla, Adriana; Carnero Contentti, Edgar; López, Pablo Adrián; Pita, Cecilia; Tavolini, Darío; Steinberg, Judith; Menichini, María Laura; Rojas, Juan Ignacio; Tizio, Santiago (Elsevier, 2022-06-18)
    Introducción El tratamiento sintomático en la esclerosis múltiple (EM) representa uno de los pilares del abordaje global de esta patología. El tratamiento específico de los síntomas tiene como objetivo reducir o eliminar ...
  • The Immune Response in Multiple Sclerosis 
    Rodríguez Murúa, Sofía; Farez, Mauricio Franco; Quintana, Francisco J. (Annual Reviews, 2021-10-04)
    Multiple sclerosis (MS) is a chronic autoimmune, inflammatory, and neurodegenerative disease that affects the central nervous system (CNS). MS is characterized by immune dysregulation, which results in the infiltration of ...
  • Acting centrally or peripherally: A renewed interest in the central nervous system penetration of disease-modifying drugs in multiple sclerosis 
    Correale, Jorge; Halfon, Mario Javier; Jack, Dominic; Rubstein, Adrián; Villa, Andrés (Elsevier, 2021-09-14)
    With the recent approval of cladribine tablets, siponimod and ozanimod, there has been a renewed interest into the extent to which these current generation disease-modifying therapies (DMTs) are able to cross into the ...
  • Neuromyelitis optica spectrum disorders: from pathophysiology to therapeutic strategies 
    Carnero Contentti, Edgar; Correale, Jorge (BioMed Central, 2021-09-16)
    Neuromyelitis optica (NMO) is a chronic inflammatory autoimmune disease of the central nervous system (CNS) characterized by acute optic neuritis (ON) and transverse myelitis (TM). NMO is caused by a pathogenic serum IgG ...
  • Interleukin-35 is a critical regulator of immunity during helminth infections associated with multiple sclerosis 
    Correale, Jorge; Marrodán, Mariano; Carnero Contentti, Edgar (Wiley, 2021-07-01)
    Multiple sclerosis (MS) is currently thought to arise by interactions between genetic susceptibility and environmental factors. Infections in general trigger autoimmune responses causing clinical manifestations of disease. ...
  • Research priorities in multiple sclerosis in Latin America: A multi-stakeholder call to action to improve patients care: Research priorities in MS in LATAM 
    Rojas, Juan Ignacio; Carnero Contentti, Edgar; Abad, Patricio; Aguayo, Adriana; Alonso, Ricardo; Bauer, Johana; Becker, Jefferson; Bustos, Andrea K.; Carcamo, Claudia A.; Carrá, Adriana; Correa Díaz, Edgar Patricio; Correale, Jorge; Cristiano, Edgardo; Diaz, Alejandro J.; Fernandez Liguori, Nora; Flores, José; Fruns, Manuel; Garcea, Orlando; Ysrraelit, María Célica; LACTRIMS working group (Elsevier, 2021-05-24)
    As human and economic resources are limited, especially in Latin America (LATAM), it is important to identify research priorities to improve multiple sclerosis (MS) patients care in the region. The objective was to generate ...
  • Multiple sclerosis care units in Latin America: Consensus recommendations about its objectives and functioning implementation 
    Cristiano, Edgardo; Abad, Patricio; Becker, Jefferson; Carrá, Adriana; Correale, Jorge; Flores, José; Fruns, Manuel; Garcea, Orlando; Garcia Bónitto, Juan; Gracia, Fernando; Hamuy, Fernando; Navas, Carlos; Patrucco, Liliana; Rivera, Víctor M.; Velazquez, Merced; Rojas, Juan Ignacio (Elsevier, 2021-10-15)
    Objective Currently, there are several reasons to promote worldwide the concept of multiple sclerosis care units (MSCU) for a better management of affected patients. Ideally, the MSCU should have some human and technical ...
  • Guías de práctica para indicación y contraindicaciones de vacunación de pacientes con esclerosis múltiple 
    Barboza, Andrés G.; Sinay, Vladimiro; Silva, Berenice Anabel; Rojas, Juan Ignacio; Ysrraelit, María Célica; Carnero Contentti, Edgar; Negrotto, Laura; Tavolini, Darío; Deri, Norma; Tizio, Santiago; Gaitán, María Inés; Luetic, Geraldine G.; Patrucco, Liliana; Martínez, Alejandra Diana; Parada Marcilla, Marcela; Hryb, Javier Pablo; Alonso, Ricardo; Bestoso, Santiago; Cabrera, Lorena M.; Cristiano, Edgardo (Elsevier, 2021-03)
    Introducción La esclerosis múltiple es una enfermedad con componente autoinmune, y un número significativo de pacientes se encuentra bajo tratamiento inmunomodulador e inmunosupresor. Frecuentemente los médicos tratantes ...
  • Accumulative risk of clinical event in high-risk radiologically isolated syndrome in Argentina: data from the nationwide registry RelevarEM 
    Rojas, Juan Ignacio; Pappolla, Agustín; Blaya, Patricio A.; Marrodán, Mariano; Ysrraelit, María Célica; Luetic, Geraldine G.; Liwacki, Susana; Barboza, Andrés G.; Burgos, Marcos; Cohen, Leila; Mainella, Carolina; Zanga, Gisela; Menichini, María Laura; Tavolini, Darío; Tkachuk, Verónica A.; López, Pablo Adrián; Leguizamon, Felisa; Knorre, Eduardo; Nofal, Pedro G.; Patrucco, Liliana (Springer, 2021-09-07)
    Introduction: We aimed to analyze the accumulative risk of MRI and OB factors for evolution from RIS to MS in subjects included in the Argentinean MS registry (NCT03375177). Methods: RIS subjects were identified according ...
  • BTK inhibitors as potential therapies for multiple sclerosis 
    Correale, Jorge (Elsevier, 2021-08-19)
    Resumen no disponible
  • Social Cognition In Early Multiple Sclerosis: Neuropsychological And Anatomical Approach 
    Crivelli, Lucía; Calandri, Ismael Luis; Helou, María Belén; Keller, Greta; Fiol, Marcela Paula; Ysrraelit, María Célica; Gaitán, María Inés; Correale, Jorge (Universidad de la Costa, 2021-03-27)
    Cognitive impairment and deficits in social cognition (SC) are frequent in patients with multiple sclerosis (MS). The aim of the present work is to study SC in patients with early MS and to analyze its neuroanatomical ...
  • Assessing attacks and treatment response rates among adult patients with NMOSD and MOGAD: Data from a nationwide registry in Argentina 
    Carnero Contentti, Edgar; López, Pablo Adrián; Pettinicchi, Juan Pablo; Criniti, Juan; Pappolla, Agustín; Miguez, Jimena; Patrucco, Liliana; Cristiano, Edgardo; Liwacki, Susana; Tkachuk, Verónica A.; Balbuena Aguirre, María Eugenia; Vrech, Carlos; Deri, Norma; Correale, Jorge; Marrodán, Mariano; Ysrraelit, María Célica; Leguizamon, Felisa; Luetic, Geraldine G.; Menichini, María Laura; Tavolini, Darío (Sage Publications, 2021-08-20)
    Abstract We aimed to examine treatment interventions implemented in patients experiencing neuromyelitis optica spectrum disorders (NMOSD) attacks (frequency, types, and response). Methods Retrospective study. Data on ...
  • Therapeutic plasma exchange in MS refractory relapses: Long-term outcome 
    Marrodán, Mariano; Crema, Santiago; Rubstein, Adrián; Alessandro, Lucas; Fernández, José; Correale, Jorge; Ysrraelit, María Célica (Elsevier, 2021-07-25)
    Introduction Therapeutic plasma exchange (TPE) is considered a treatment option for steroid-refractory multiple sclerosis (MS) relapses. Our objective was to assess long-term clinical response to TPE in MS steroid-refractory ...
  • Status of the neuromyelitis optica spectrum disorder in Latin America 
    Rivera, Víctor M.; Hamuy, Fernando; Rivas, Verónica; Gracia, Fernando; Rojas, Juan Ignacio; Bernardi Bichuetti, Denis; Villa, Andrés; Daccach Marques, Vanessa; Soto, Arnoldo; Bertado Cortez, Brenda; Treviño Frenk, Irene; Galleguillos Goiry, Lorna; Quiñones, Jairo; Ramírez, Deyanira A.; Caparo Zamalloa, César; Ciampi, Ethel; Lana Peixoto, Marco A.; Rodríguez, Emmanuel; Zarco, Luis; Correale, Jorge (Elsevier, 2021-06-14)
    Background Neuromyelitis optica spectrum disorders (NMOSD) is an increasing diagnostic and therapeutic challenge in Latin America (LATAM). Despite the heterogeneity of this population, ethnic and socioeconomic commonalities ...
  • Real-world effectiveness of natalizumab treatment in patients with relapsing multiple sclerosis in Argentina and Chile 
    Ysrraelit, María Célica; Caride, Alejandro; Sinay, Vladimiro; Rivera Kindel, Mario; Halfon, Mario Javier; Patrucco, Liliana; Piedrabuena, Raúl; Diaz Aragunde, Vanina Eleonor (Associacao Arquivos De Neuro-Psiquitria Dr Oswaldo Lange, 2021-05-01)
    Background: The real-world effectiveness of natalizumab in people with relapsing multiple sclerosis (PwRMS) in Argentina and Chile has not been reported. Objective: To evaluate the effectiveness of natalizumab treatment ...
  • Rituximab- and ocrelizumab-induced early- and late-onset neutropenia in a multiple sclerosis patient 
    Marrodán, Mariano; Laviano, Julia; Oneto, Sofía; Reino, Fabricio M.; Delorme, Ricardo; Fornillo, Florencia; Fernández, José; Correale, Jorge (Springer, 2021-06-01)
    Resumen no disponible
  • Aggressive multiple sclerosis in Argentina: Data from the nationwide registry RelevarEM 
    Kohler, Matías; Kohler, Eduardo; Vrech, Carlos; Pappolla, Agustín; Miguez, Jimena; Patrucco, Liliana; Correale, Jorge; Marrodán, Mariano; Gaitán, María Inés; Fiol, Marcela Paula; Negrotto, Laura; Ysrraelit, María Célica; Cristiano, Edgardo; Carrá, Adriana; Steinberg, Judith; Martinez, Alejandra D.; Curbelo, María Celeste; Cohen, Leila; Alonso, Ricardo; Garcea, Orlando (Elsevier, 2021-06-01)
    The objectives of the present study were to describe the frequency of aggressive multiple sclerosis (aMS) as well as to compare clinical and radiological characteristics in aMS and non-aMS patients included in RelevarEM ...

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