• Real-World Effectiveness and Safety of Cladribine in Multiple Sclerosis: Longitudinal Data From the Nationwide Registry in Argentina 

  Rojas, Juan Ignacio; Alonso, Ricardo; Luetic, Geraldine; Patrucco, Liliana; Casas, Magdalena; Silva, Berenice; Miguez, Jimena; Deri, Norma; Vrech, Carlos; Liwacki, Susana; Piedrabuena, Raúl; Silva, Emanuel; Tkachuk, Verónica; Burgos, Marcos; Tavolini, Darío; Zanga, Gisela; Alvez Pinheiro, Amelia; Hryb, Javier; Leguizamon, Felisa; Knorre, Eduardo; Lopez, Pablo A.; Martínez, Alejandra; Carrá, Adriana; Alonso Serena, Marina; Cristiano, Edgardo; Correale, Jorge; Garcea, Orlando; Fernández Liguori, Nora; Carnero Contentti, Edgar (Lippincott Williams & Wilkins, 2024-05-23)

  Objective: The aim was to evaluate patient profiles, effectiveness and safety of cladribine (CLAD) in patients with relapsing-remitting multiple sclerosis in Argentina. Methods: This was a substudy included in RelevarEM ...
• Country-level gender inequality is associated with structural differences in the brains of women and men 

  Zugman, Andre; Alliende, Luz María; Medel, Vicente; A I Bethlehem, Richard; Seidlitz, Jakob; Ringlein, Grace; Arango, Celso; Arnatkevičiūtė, Aurina; Asmal, Laila; Bellgrove, Mark; Benegal, Vivek; Bernardo, Miquel; Billeke, Pablo; Bosch-Bayard, Jorge; Bressan, Rodrigo; Busatto, Geraldo F.; Castro, Mariana Nair; Chaim-Avancini, Tiffany; Compte, Albert; Villarreal, Mirta Fabiana (National Academy of Sciences, 2023-05-16)

  Gender inequality across the world has been associated with a higher risk to mental health problems and lower academic achievement in women compared to men. We also know that the brain is shaped by nurturing and adverse ...
• Molecular neuroimaging in dominantly inherited versus sporadic early-onset Alzheimer's disease. 

  Iaccarino, Leonardo; Llibre Guerra, Jorge J.; McDade, Eric; Edwards, Lauren; Gordon, Brian; Benzinger, Tammie; Hassenstab, Jason; Kramer, Joel H.; Li, Yan; Mille, Bruce L.; Miller, Zachary; Morris, John C.; Mundada, Nidhi; Perrin, Richard J.; Rosen, Howard J.; Soleimani Meigooni, David; Strom, Amelia; Tsoy, Elena; Wang, Guoqiao; Xiong, Chengjie; Allegri, Ricardo Francisco; Chrem Méndez, Patricio Alexis; Vázquez, Silvia (Oxford University Press, 2024-05-03)

  Approximately 5% of Alzheimer's disease patients develop symptoms before age 65 (early-onset Alzheimer's disease), with either sporadic (sporadic early-onset Alzheimer's disease) or dominantly inherited (dominantly inherited ...
• Efficacy and safety of erdafitinib in pediatric patients with advanced solid tumors and FGFR alterations in the phase 2 RAGNAR trial 

  Olaf Witt, Sameer Farouk Sait; Diez, Blanca; Cardoso, Agustín; Reardon, David A.; Welsh, Liam; Shih, Kent C.; Baldini, Capucine; Massard, Christophe; Loriot, Yohann; Pant, Shubham; Sweiti, Hussein; Thomas, Shibu; Hammond, Constance; Najmi, Saltanat; Triantos, Spyros; Crow, Lauren; Geoerger, Birgit (American Society of Clinical Oncology, 2024-06)

  Background: Erdafitinib is an oral selective pan-fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitor approved in the US for adult patients (pts) with locally advanced or metastatic urothelial carcinoma with ...
• Clinical efficacy of a next-generation sequencing (NGS) and immunohistochemistry (IHC) panel in patients with advanced cancer in Argentina. 

  Cantarella, Florencia; Mendoza Bertelli, Andrea; Girotti, Romina; Marino, Ana Clara; Brest, Esteban; Dibarbora, Delfina; Mahmoud, Yamil; Veigas, Florencia; Enrico, Diego Hernan; Tsou, Florencia; Lacava, Juan A.; Piazzoni, Luciano; Riso, Aldo Alejandro; Martinengo, Gastón L.; Rodriguez, Andrés; Beguelin, Zenon; Cerrato, Sebastián; Jerez, Ignacio; Salanova, Rubén (American Society of Clinical Oncology, 2024-05-29)

  Background: The analysis of somatic genomic alterations, evaluation of DNA mismatch repair (MMR) proteins, and examination of PD-L1 expression in tumor biopsies are crucial for prognosis and informed therapeutic decisions. ...

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