• Microbiome-derived metabolites from vitamin B2 and B9 pathways modulate MAIT cells from multiple sclerosis patients 

  Correale, Jorge; Marrodán, Mariano; Piedrabuena, María Agustina; Soman, Karthik; Farez, Mauricio Franco; Baranzini, Sergio E. (SAGE, 2026-06-01)

  Background: Mucosal-associated invariant T (MAIT) cells recognize microbial vitamin B2 and B9 metabolites via MR1 and have been implicated in multiple sclerosis (MS). How patient-specific gut microbiota shape human MAIT-cell ...
• Awareness, attitudes, and barriers toward Transthyretin Amyloid Cardiomyopathy in Latin America: A questionnaire-based cross-sectional study. 

  Camacho-Hubner, Cecilia; Waddington Cruz, Marcia; Rodríguez González, María Juliana; Simões, Marcus Vinicius; López-Ponce de León, Juan David; Fernandes, Fabio; Martínez Carreño, Erika María; Costabel, Juan Pablo; Berríos Bárcenas, Enrique A.; Barroso, Fabio Adrián; Cigarroa López, José Angel; Ortega Reyes, Rosa; Alvarez, Jaime; Pérez de Arenaza, Diego; Buitrago, Diana; Otero, Constanza; Bertoli de Souza, Claudenice Leite; Molina Gómez, Juan Sebastián; Silva Julian, Guilherme (Public Library of Science, 2026-06-26)

  Background: Cardiac Amyloidosis (CA), specifically Transthyretin Amyloid Cardiomyopathy (ATTR-CM), is an under-recognized, progressive, and fatal disease. Comprehensive primary data describing awareness, attitudes, and ...
• Endovascular embolization of tentorial dural arteriovenous fistulas (EMBOTENT): a retrospective multicenter study 

  Vollherbst, Dominik F.; Krug, Nadja; Zhang, Peng; Ma, Yongjie; Su, Xin; Limbucci, Nicola; Renieri, Leonardo; Mosimann, Pascal J.; Boutet, Alexandre; Cheng, How-Chung; Marnat, Gaultier; Barreau, Xavier; Szikora, Istvan; Czencz, Máté; González, Alejandro; Albóniga-Chindurza, Asier de; Scarcia, Luca; Kalsoum, Erwah; Alexandre, Andrea M.; Pujol Lereis, Virginia Andrea (BMJ Publishing Group, 2026-05-04)

  Background: Tentorial dural arteriovenous fistulas (TDAVFs) are rare but high risk vascular lesions. Although endovascular embolization is often the preferred treatment, large scale data on efficacy and safety are limited. ...
• Generation of a human induced pluripotent stem cell line (FLENIi004-A) from an Autosomal-Dominant Alzheimer's disease PSEN1 p.M146L patient 

  Vautier, Mercedes Florencia; Chrem Méndez, Patricio Alexis; Jerez Ferreyra, Guillermo; Massazza, Victoria; Apecetche, Manuela; Rodríguez Varela, María Soledad; Clas, Giulia Solange; Nievas, Micaela; Allegri, Ricardo Francisco; Sevlever, Gustavo Emilio; Scassa, María Élida; Surace, Ezequiel Ignacio; Marazita, Mariela Claudia; Romorini, Leonardo (Elsevier, 2026-06)

  Human induced pluripotent stem cell (hiPSC) line FLENIi004-A was generated from peripheral blood mononuclear cells (PBMCs) using the lentiviral-hSTEMCCA-loxP vector. FLENIi004-A was derived from a 41-year-old Argentinean ...
• Identification of genetic modifiers of autosomal dominant Alzheimer's disease: a genome-wide association study 

  Patel, Maulikkumar; Feng, Wei; McKay, Nicole S.; Millar, Peter R.; Liu, Menghan; Yang, Chengran; Cetin, Arda; Johnson, Matthew; Budde, John P.; Western, Daniel; Marsh, Thomas W.; Saliu, Ibrahim O.; Gordon, Brian A.; Llibre Guerra, Jorge J.; Morris, John C.; Bateman, Randall J.; Allegri, Ricardo Francisco; Chrem Méndez, Patricio Alexis; Surace, Ezequiel Ignacio; Vázquez, Silvia (Lancet, 2026-06)

  Background: Individuals with autosomal dominant Alzheimer's disease (ADAD) arising from mutations in PSEN1, PSEN2, or APP exhibit variability in clinical presentation. Genetic studies of ADAD have shaped our understanding ...

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