Repositorio Institucional Fleni

El Repositorio Institucional Fleni tiene el objetivo reunir, almacenar, preservar y difundir la producción científico-académica de la Institución producto de sus actividades de investigación y docencia, a fin de ponerlas a disposición de la comunidad para su uso, tendiendo a aumentar la visibilidad y la difusión de los documentos generados y colaborar así en la construcción de su memoria institucional.

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  • Refining pituitary adenoma classification: the role of transcription factors in diagnosis and risk assessment 
    Katz, Débora Adela; Slavinsky, Patricia; Pernas, Mariana Gonzalez; Battistone, Maria Florencia; Pingel, Jesica; Arakaki, Naomi; Mezmezian, Mónica Beatriz; Sevlever, Gustavo Emilio; Rojas, Estefanía; Schultz, Marcelo; Cervio, Andrés Eduardo (bioscientifica, 2025-03-10)
    JOINT1942 Introduction: The new classification of pituitary tumors (WHO 2022) is based on transcription factors (TF) detected through immunohistochemistry (IHC) to determine tumor lineage. The aim of our study was to ...
  • Cultural adaptation and validation of the Argentine Children's Orientation and Amnesia Test 
    Dorrego, María Flavia; Colbert, Alison Margaret; Ewing-Cobbs, Linda; Andreu, Mauro Federico (Taylor & Francis, 2025-03-17)
    The Children's Orientation and Amnesia Test (COAT) is a widely used tool for assessing post-traumatic amnesia (PTA) in children, yet no validated Spanish version exists. This study aimed to translate, culturally adapt, and ...
  • Toward equity in MS care: A roadmap for accessible treatment 
    Correale, Jorge (Sage, 2025-03-17)
    Resumen no disponible
  • Generation of human induced pluripotent stem cell lines from two down syndrome patients, including a down syndrome/Alzheimer's disease case (FLENIi002-A) and a beta-amyloid-resistant case (FLENIi003-A) 
    Clas, Giulia Solange; Marazita, Mariela Claudia; Pertierra, Lucía; Vázquez, Silvia; Isaja, Luciana; Rodríguez Varela, María Soledad; Mucci, Sofía; Helou, María Belén; Tapajóz Pereira de Sampaio, Fernanda; Magrath Guimet, Nahuel; Bérgamo, Yanina; Allegri, Ricardo Francisco; Sevlever, Gustavo Emilio; Scassa, María Élida; Surace, Ezequiel Ignacio; Romorini, Leonardo (Elsevier, 2025-05-01)
    Two human induced pluripotent stem cell (hiPSC) lines, FLENIi002-A and FLENIi003-A, were generated from peripheral blood mononuclear cells (PBMCs) using the lentiviral-hSTEMCCA-loxP vector. FLENIi002-A was derived from a ...
  • Resistance and resilience to Alzheimer's disease in Down syndrome 
    Boyle, Rory; Koops, Elouise A.; Ances, Beau; Andrews, Elizabeth J.; Arenaza-Urquijo, Eider M.; Benjanin, Alexandre; Brickman, Adam M.; Buckley, Rachel F.; Clas, Giulia Solange; Costello, Emmet; Coughlan, Gillian T.; Conley, Alexander C.; Deng, Feng; de Paula Faria, Daniele; Edwards, Natalie; Flores-Aguilar, Lisi; Fortea, Juan; Saidi, Ladan Ghazi; Head, Elizabeth; Hom, Christy L. (Wiley, 2025-04-28)
    Due to the high prevalence of Alzheimer's disease (AD) in adults with Down syndrome (DS), trisomy 21 is now considered a genetic form of AD (DSAD). A better understanding of factors that can prevent or delay AD is vital ...

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